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Games Like Bacteria

60+ similar titles based on shared tags and player behavior. Themes include Casual, Puzzle, Indie, Singleplayer.

Bacteria header art

'Bacteria' - A relaxing puzzle game based on the rules of the cellular automaton ‘Life’ devised by John Horton Conway in 1970.

Reviews: Mixed — 57% — of 422 reviews
Released: 2016-03-23
Developer: Sometimes You
Genres: Casual, Indie
Platforms: Windows, Mac, Linux
Median playtime: 5.6 hrs
Mean playtime: 6.5 hrs
Players ≥ 1 hr: 97%

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  1. #1 Energy Cycle
    97% matchMixed69% of 295 reviews2016
    Dev: Sometimes You
    Windows · Mac · Linux
    Median: 3.3 hrsMean: 4.9 hrs≥1hr: 96%

    'Energy Cycle' – new puzzle game from the developers of ‘Energy Balance’. When you click each cell on the game field - it changes color, and the colors of adjacent cells horizontally and vertically. Your task to bring all the cells to the same color. Sounds pretty easy, but try to do it!

    Why similar: Casual 90.1%, Indie 9.9%

  2. #2 Splice
    96% matchVery Positive87% of 590 reviews2012
    Dev: Cipher Prime Studios
    Windows · Linux
    Median: 30 minMean: 5.5 hrs≥1hr: 39%

    Splice is an experimental and artistic puzzler. Immerse yourself in its microbial world and start splicing! Every level ("strand") consists of a number of cells that you will need to rearrange into a target structure in several moves ("splices").

    Why similar: Casual 73%, Indie 27%

  3. #3 Containment
    96% matchVery Positive85% of 53 reviews2018
    Dev: Finite Reflection Studios
    Windows · Mac · Linux

    Containment is a turn-based, minimalist strategy game about managing the growth of bacteria. Use antibiotics to keep their power under control as you work towards containment.

    Why similar: Casual 77.7%, Indie 22.3%

  4. #4 SquareCells
    94% matchVery Positive90% of 1,267 reviews2015
    Dev: Matthew Brown
    Windows · Mac · Linux
    Median: 4.1 hrsMean: 5.3 hrs≥1hr: 74%

    SquareCells is an ambient logic puzzle game.

    Why similar: Casual 72.2%, Indie 27.8%

  5. #5 Multimirror
    95% matchMixed40% of 143 reviews2016
    Dev: Cleverweek
    Windows · Mac · Linux
    Median: 3.0 hrsMean: 3.8 hrs≥1hr: 94%

    Multimirror is a minimal grid-based puzzle game.

    Why similar: Casual 67.2%, Indie 32.8%

  6. #6 Dexodonex
    94% matchVery Positive84% of 221 reviews2016
    Dev: Volens Nolens Games
    Windows
    Median: 3.1 hrsMean: 4.0 hrs≥1hr: 84%

    Hexagonal puzzle with the ability to edit levels

    Why similar: Casual 88.4%, Indie 11.6%

  7. #7 Puzlogic
    93% matchVery Positive88% of 50 reviews2018
    Dev: Eduardo Barreto
    Windows · Mac · Linux

    Unique puzzle game inspired by sudoku and kakuro (cross sums).

    Why similar: Casual 68.8%, Indie 31.2%

  8. #8 OXXO
    91% matchVery Positive95% of 292 reviews2019
    Dev: Hamster On Coke Games
    Windows · Mac · Linux
    Median: 2.6 hrsMean: 4.3 hrs≥1hr: 83%

    Ever evolving puzzle game.

    Why similar: Casual 76.8%, Indie 23.2%

  9. #9 Supesu
    92% matchMostly Positive79% of 52 reviews2018
    Dev: Growfall Games
    Windows

    Welcome to Supesu. Relaxing dimensional puzzle game.

    Why similar: Casual 76%, Indie 24%

  10. #10 Shoot. Push. Repeat.
    91% matchVery Positive84% of 76 reviews2020
    Dev: CrewLab
    Windows

    A dynamic clicker puzzle simulating real physics.

    Why similar: Casual 76.5%, Indie 23.5%

  11. #11 CrossCells
    90% matchVery Positive83% of 912 reviews2017
    Dev: Matthew Brown
    Windows · Mac · Linux
    Median: 1.9 hrsMean: 3.0 hrs≥1hr: 63%

    CrossCells is an ambient logic puzzle game.

    Why similar: Casual 76.6%, Indie 23.4%

  12. #12 Inline
    89% matchVery Positive94% of 124 reviews2018
    Dev: Light Bringer Games inc.
    Windows · Mac · Linux
    Median: 2.6 hrsMean: 4.7 hrs≥1hr: 63%

    Inline is an atmospheric, relaxing and minimalist experience reminiscent of classic puzzle games. Arrange the shapes you are given on a grid to form and clear as many lines as possible in this simple yet challenging game.

    Why similar: Casual 79.5%, Indie 20.5%

  13. #13 Auto Cell: Game of Life
    88% matchVery Positive86% of 70 reviews2021
    Dev: 日辰星火
    Windows

    Auto Cell run in a two-dimensional grid world. Each grid can be regarded as a small life. It has two states: survival or death.

    Why similar: Casual 100%

  14. #14 Square Logic
    86% matchVery Positive98% of 83 reviews2023
    Dev: Climbing Goat Games
    Windows · Linux

    Square Logic is a minimalist puzzle game about coloring the grid with squares and rectangles, respecting the number of each cell.

    Why similar: Casual 100%

  15. #15 Estiman: Game of Estimation
    89% matchVery Positive83% of 58 reviews2016
    Dev: Kool2Play
    Windows
    Median: 3.5 hrsMean: 4.2 hrs≥1hr: 96%

    ESTIMAN is a relaxing arcade game with original estimation-based gameplay

    Why similar: Indie 56.3%, Casual 43.7%

  16. #16 TRIOS - lofi beats / numbers to chill to
    87% matchVery Positive91% of 53 reviews2021
    Dev: Samurai Punk
    Windows · Mac · Linux

    TRIOS is a relaxing, minimalist maths puzzle game. Take your time, chill out with some numbers. Deceptively simple, surprisingly challenging.

    Why similar: Casual 85.7%, Indie 14.3%

  17. #17 LOOP: A Tranquil Puzzle Game
    86% matchVery Positive97% of 136 reviews2015
    Dev: John Cullen
    Windows · Mac · Linux

    LOOP is a tranquil puzzle game, with a unique, simple, meditative feel. Inspired by Zen philosophy, the minimal UI has no timers, move limit or score; allowing you to just relax and focus. Includes over 1 BILLION Levels.

    Why similar: Casual 76.7%, Indie 23.3%

  18. #18 Sorting Inc
    82% matchVery Positive94% of 110 reviews2025
    Dev: AstroTechnician
    Windows · Linux

    A casual and relaxing game about sorting various items. Join Sorting Inc and climb up through the departments to become the absolute expert in the field of sorting.

    Why similar: Casual 74.7%, Indie 25.3%

  19. #19 hocus 2
    84% matchVery Positive86% of 71 reviews2021
    Dev: Yunus Ayyildiz
    Windows · Mac

    ■■■■■■■..........º.......º......º.......

    Why similar: Casual 90.6%, Indie 9.4%

  20. #20 Atomic Reconstruction
    85% matchMostly Positive77% of 60 reviews2016
    Dev: Teawork Dev
    Windows · Linux
    Median: 3.3 hrsMean: 4.9 hrs≥1hr: 76%

    Atomic Reconstruction is a atmospheric Puzzle game, where you have to use the power of fusion and fission to create and modify specific atoms or groups of atoms.

    Why similar: Casual 75.4%, Indie 24.6%

  21. #21 Zen of Sudoku
    84% matchVery Positive89% of 375 reviews2006
    Dev: Unknown Worlds Entertainment
    Windows
    Median: 1.5 hrsMean: 72.1 hrs≥1hr: 61%

    From the creators of Natural Selection comes Zen of Sudoku, a relaxing, easy to play version of Sudoku for your PC.Relax with hand-painted Japanese-styled backgrounds, no timer and lush natural soundscapes.Stimulates your brain to keep it healthy and alert.

    Why similar: Casual 79.7%, Indie 20.3%

  22. #22 Mega Mosaic
    80% matchVery Positive91% of 456 reviews2024
    Dev: Mark FfrenchPub: Divide The Plunder
    Windows · Mac
    Median: 28.5 hrsMean: 48.9 hrs≥1hr: 87%

    Mega Mosaic is a meditative game about completing a single enormous puzzle

    Why similar: Casual 100%

  23. #23 Swapperoo
    83% matchVery Positive92% of 78 reviews2015
    Dev: Fallen Tree Games Ltd
    Windows
    Median: 3.0 hrsMean: 3.9 hrs≥1hr: 92%

    The friendly puzzle game intent on your defeat.

    Why similar: Casual 76%, Indie 24%

  24. #24 Meta Sudoku
    79% matchVery Positive81% of 81 reviews2023
    Dev: Matrix Science
    Windows

    Meta Sudoku is a minimalist game, fresh interface and quiet music is very suitable for relaxation, reduce fatigue, give you the most comfortable experience.

    Why similar: Casual 100%

  25. #25 Circularity
    82% matchMixed61% of 66 reviews2017
    Dev: Giorgi AbelashviliPub: SA Industry
    Windows · Mac · Linux
    Median: 36 minMean: 8.3 hrs≥1hr: 42%

    Relaxing puzzle with interesting game mechanics - bring your character to the final portal which will transit you to the next level. You will need to move straight, avoid obstacles, jump through portals, ricochet from walls and a lot more.

    Why similar: Casual 76%, Indie 24%

  26. #26 ClickCells: CPU girls
    81% matchVery Positive90% of 98 reviews2020
    Dev: Crew Lab
    Windows

    A casual clicker puzzle simulating real physics.

    Why similar: Casual 75.9%, Indie 24.1%

  27. #27 Jacob
    81% matchMostly Negative36% of 102 reviews2016
    Dev: Duck Duck ZeusPub: Centre For Longitudinal Studies
    Windows

    Jacob: an evidence-based puzzle

    Why similar: Casual 74.3%, Indie 25.7%

  28. #28 Linked
    78% matchVery Positive91% of 583 reviews2017
    Dev: ThinkOfGamesPub: Conglomerate 5
    Windows
    Median: 3.0 hrsMean: 19.8 hrs≥1hr: 83%

    Relaxing, minimalistic 2d-puzzle game.

    Why similar: Casual 70.5%, Indie 29.5%

  29. #29 808s&Genetics
    76% matchVery Positive98% of 81 reviews2023
    Dev: Magnesiumteng Machine
    Windows

    A puzzle game that combines nonogram and genetics rules.

    Why similar: Casual 88.7%, Indie 11.3%

  30. #30 Chicken Labyrinth Puzzles
    79% matchMixed68% of 231 reviews2018
    Dev: ZemunBREPub: SA Industry
    Windows
    Median: 2.8 hrsMean: 3.4 hrs≥1hr: 86%

    Guide a lost chicken through a series of mazes and puzzles as it searches for the way home.

    Why similar: Casual 82.9%, Indie 17.1%

  31. #31 Quell
    78% matchVery Positive98% of 452 reviews2015
    Dev: Fallen Tree Games LtdPub: Green Man Gaming Publishing
    Windows
    Median: 2.2 hrsMean: 7.8 hrs≥1hr: 69%

    An enchanting game of logic and relaxation.

    Why similar: Casual 67.2%, Indie 32.8%

  32. #32 Unitied
    77% matchVery Positive98% of 53 reviews2019
    Dev: Peter Hijma
    Windows · Mac · Linux

    Unitied is a minimalistic & relaxing puzzle game

    Why similar: Casual 76.5%, Indie 23.5%

  33. #33 PEG
    77% matchVery Positive92% of 256 reviews2017
    Dev: Arzola's
    Windows · Mac · Linux
    Median: 3.1 hrsMean: 4.9 hrs≥1hr: 86%

    Blue eats blue. Red eats red. Until one of each remains. A puzzler that is deceptively simple but hard to master.

    Why similar: Casual 75.5%, Indie 24.5%

  34. #34 Delete
    74% matchOverwhelmingly Positive96% of 1,691 reviews2018
    Dev: PONY
    Windows · Mac
    Median: 2.7 hrsMean: 62.5 hrs≥1hr: 79%

    Let the number tell you what to do

    Why similar: Casual 78.1%, Indie 21.9%

  35. #35 Colors!
    75% matchVery Positive83% of 94 reviews2021
    Dev: Vergiu
    Windows

    Minimalist and intuitive puzzle game with relaxing music.

    Why similar: Casual 70.5%, Indie 29.5%

  36. #36 Quell Reflect
    76% matchVery Positive94% of 193 reviews2015
    Dev: Fallen Tree Games LtdPub: Green Man Gaming Publishing
    Windows
    Median: 1.8 hrsMean: 12.8 hrs≥1hr: 66%

    An enchanting puzzle game of logic and relaxation.

    Why similar: Casual 65%, Indie 35%

  37. #37 Quell Memento
    75% matchVery Positive96% of 227 reviews2015
    Dev: Fallen Tree Games LtdPub: Green Man Gaming Publishing
    Windows
    Median: 3.2 hrsMean: 9.4 hrs≥1hr: 71%

    An enchanting puzzle game of logic and relaxation.

    Why similar: Casual 60.7%, Indie 39.3%

  38. #38 Post Apocalypse Microbe Lab
    70% matchVery Positive95% of 60 reviews2026
    Dev: SKIPMOREPub: Flyhigh Works
    Windows · Mac

    This is an idle game you can leave in the corner of your desktop. Watch at your leisure as an android girl researches microbes in a post-apocalyptic world.

    Why similar: Casual 89.7%, Indie 10.3%

  39. #39 Scalak
    73% matchOverwhelmingly Positive97% of 1,129 reviews2018
    Dev: Hamster On Coke Games
    Windows · Mac · Linux
    Median: 2.6 hrsMean: 3.9 hrs≥1hr: 78%

    Fulfilling puzzle game.

    Why similar: Casual 82.1%, Indie 17.9%

  40. #40 Lines Infinite
    74% matchVery Positive91% of 588 reviews2017
    Dev: KonstructorsPub: Hook Games
    Windows · Mac · Linux
    Median: 2.0 hrsMean: 3.4 hrs≥1hr: 63%

    Beautiful & relaxing Numberlink puzzles.

    Why similar: Casual 76.9%, Indie 23.1%

  41. #41 My Sudoku
    72% matchMostly Positive75% of 103 reviews2024
    Dev: Dr. Cyril Splutterworth
    Windows

    Beginners, casual players and experts will find an enjoyable challenge in My Sudoku. Solve puzzles at your own pace in a pleasant and relaxing atmosphere.

    Why similar: Casual 100%

  42. #42 Astra Ignota
    69% matchVery Positive93% of 55 reviews2025
    Dev: Xavi Artigas
    Windows

    A relaxing, space-themed puzzle game where you fill a board using symmetrical figures, while uncovering a mysterious sci-fi story. All boards are hand-crafted for maximum enjoyment.

    Why similar: Casual 100%

  43. #43 Wayout
    72% matchVery Positive88% of 1,177 reviews2016
    Dev: KonstructorsPub: Hook Games
    Windows · Mac · Linux
    Median: 2.9 hrsMean: 7.6 hrs≥1hr: 78%

    Relax, clear your mind and find the way out.

    Why similar: Casual 73.7%, Indie 26.3%

  44. #44 Hex
    73% matchVery Positive88% of 58 reviews2017
    Dev: Studio Goya
    Windows · Mac
    Median: 1.2 hrsMean: 4.2 hrs≥1hr: 60%

    Hex is a unique puzzle game with a simple goal, clear the tiles to win. Tiles might multiply, explode, toggle on and off, and more as you jump between them in this exciting journey through over 80 challenging levels.

    Why similar: Casual 56.6%, Indie 43.4%

  45. #45 Puzzle - LINES AND KNOTS
    71% matchVery Positive87% of 261 reviews2020
    Dev: PlayToday
    Windows

    Logical puzzle game for meditation. The goal of the player is to assemble a puzzle consisting of nodes. Easy to understand mechanics, swap hexagons with lines.

    Why similar: Casual 79.3%, Indie 20.7%

  46. #46 Microcosmum: survival of cells
    70% matchVery Positive84% of 1,421 reviews2015
    Dev: Satur Entertainment
    Windows
    Median: 3.4 hrsMean: 5.5 hrs≥1hr: 92%

    Microcosmum: survival of cells. Join the wonderful and amazing world of microorganisms.

    Why similar: Casual 100%

  47. #47 Game Of Puzzles: Nature
    71% matchVery Positive90% of 52 reviews2019
    Dev: Snkl Studio
    Windows

    A puzzle game in which you have to assemble a single image from individual pieces.

    Why similar: Casual 76%, Indie 24%

  48. #48 Bombe
    66% matchVery Positive96% of 385 reviews2023
    Dev: Charlie Brej
    Windows · Mac · Linux

    Minesweeper, but you only solve each situation once.

    Why similar: Casual 100%

  49. #49 Puzzle Car
    68% matchVery Positive94% of 108 reviews2021
    Dev: Rising Moon Games
    Windows · Linux

    A minimalist and relaxing experience. Challenge yourself to move pieces to assemble a safe path for your car and collect all the items on the way, while listening to a relaxing soundtrack in a totally minimalist environment.

    Why similar: Casual 81.4%, Indie 18.6%

  50. #50 Hexcells
    68% matchOverwhelmingly Positive97% of 5,925 reviews2014
    Dev: Matthew Brown
    Windows · Mac · Linux
    Median: 2.1 hrsMean: 4.7 hrs≥1hr: 70%

    Hexcells is an ambient logic puzzle game for PC, Mac and Linux.

    Why similar: Casual 78.9%, Indie 21.1%

  51. #51 Sandtrix+
    66% matchVery Positive93% of 157 reviews2023
    Dev: msky
    Windows · Mac · Linux

    Retro Falling Sand Puzzle Game

    Why similar: Casual 75.1%, Indie 24.9%

  52. #52 Lines X
    69% matchVery Positive82% of 984 reviews2017
    Dev: KonstructorsPub: Hook Games
    Windows · Mac · Linux
    Median: 1.3 hrsMean: 28.5 hrs≥1hr: 58%

    Beautiful & relaxing Numberlink puzzles.

    Why similar: Casual 79.1%, Indie 20.9%

  53. #53 Hexcells Infinite
    67% matchOverwhelmingly Positive97% of 4,699 reviews2014
    Dev: Matthew Brown
    Windows · Mac · Linux
    Median: 6.9 hrsMean: 36.8 hrs≥1hr: 78%

    Hexcells Infinite is an ambient logic puzzle game for PC, Mac and Linux.

    Why similar: Casual 79.1%, Indie 20.9%

  54. #54 ClickCells: Winter Lady
    69% matchVery Positive87% of 59 reviews2020
    Dev: Crew Lab
    Windows

    Erotic casual puzzle!

    Why similar: Casual 76.3%, Indie 23.7%

  55. #55 Perfection.
    73% matchMixed39% of 66 reviews2013
    Dev: Greg Lobanov
    Windows · Mac
    Median: 6 minMean: 10.7 hrs≥1hr: 13%

    Perfection. is a simple, soothing puzzle game about cutting shapes to fit into outlines. There are an infinite number of puzzles, each randomly generated to be unique and interesting.Its gameplay is very minimalistic and very forgiving; there is no time limit, and you can cut as many times as you want and undo as many times as you want...

    Why similar: Casual 77.9%, Indie 22.1%

  56. #56 Cozy Sudoku
    65% matchMostly Positive77% of 178 reviews2024
    Dev: CozyPuzzleGames
    Windows · Linux

    Sudoku, tunes, and some furry friends.

    Why similar: Casual 81.3%, Indie 18.7%

  57. #57 Puzzle Galaxies
    70% matchMixed59% of 180 reviews2016
    Dev: Evermore Game StudiosPub: Sometimes You
    Windows · Mac
    Median: 3.3 hrsMean: 3.5 hrs≥1hr: 90%

    Puzzle Galaxies is a groundbreaking puzzle video game similar to games like Bejeweled and Candy Crush. You must match jewels stored in a space station in a manner similar to Bejeweled, but there's a twist - there are enemies that will come by and try to take matching jewels on you!

    Why similar: Casual 62.9%, Indie 37.1%

  58. #58 Brainfuck Challenge
    63% matchVery Positive98% of 53 reviews2025
    Dev: Lyric Law
    Windows · Mac · Linux

    A minimalist programming puzzle game based on the esoteric language Brainfuck. Learn its rules, solve clever challenges, and even run your code in an external terminal.

    Why similar: Casual 72.5%, Indie 27.5%

  59. #59 LYSER
    68% matchVery Positive90% of 87 reviews2019
    Dev: Growfall Games
    Windows

    Casual puzzle with laser reflections.

    Why similar: Casual 76%, Indie 24%

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Games Like Bacteria

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