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Games Like Bacteria

60+ similar titles based on shared tags and player behavior. Themes include Casual, Puzzle, Indie, Singleplayer.

Bacteria header art

'Bacteria' - A relaxing puzzle game based on the rules of the cellular automaton ‘Life’ devised by John Horton Conway in 1970.

Reviews: Mixed — 57% — of 415 reviews
Released: 2016-03-23
Developer: Sometimes You
Genres: Casual, Indie
Platforms: Windows, Mac, Linux
Median playtime: 5.5 hrs
Mean playtime: 6.5 hrs
Players ≥ 1 hr: 97%

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  1. #1 Energy Cycle
    97% matchMixed69% of 294 reviews2016
    Dev: Sometimes You
    Windows · Mac · Linux
    Median: 3.3 hrsMean: 4.9 hrs≥1hr: 96%

    'Energy Cycle' – new puzzle game from the developers of ‘Energy Balance’. When you click each cell on the game field - it changes color, and the colors of adjacent cells horizontally and vertically. Your task to bring all the cells to the same color. Sounds pretty easy, but try to do it!

    Why similar: Casual 90%, Indie 10%

  2. #2 Containment
    96% matchVery Positive85% of 52 reviews2018
    Dev: Finite Reflection Studios
    Windows · Mac · Linux

    Containment is a turn-based, minimalist strategy game about managing the growth of bacteria. Use antibiotics to keep their power under control as you work towards containment.

    Why similar: Casual 77.5%, Indie 22.5%

  3. #3 Splice
    96% matchVery Positive87% of 588 reviews2012
    Dev: Cipher Prime Studios
    Windows · Linux
    Median: 30 minMean: 5.4 hrs≥1hr: 39%

    Splice is an experimental and artistic puzzler. Immerse yourself in its microbial world and start splicing! Every level ("strand") consists of a number of cells that you will need to rearrange into a target structure in several moves ("splices").

    Why similar: Casual 72.7%, Indie 27.3%

  4. #4 SquareCells
    95% matchVery Positive90% of 1,236 reviews2015
    Dev: Matthew Brown
    Windows · Mac · Linux
    Median: 4.0 hrsMean: 5.3 hrs≥1hr: 74%

    SquareCells is an ambient logic puzzle game.

    Why similar: Casual 71.8%, Indie 28.2%

  5. #5 Multimirror
    94% matchMostly Negative40% of 143 reviews2016
    Dev: Cleverweek
    Windows · Mac · Linux
    Median: 3.0 hrsMean: 3.8 hrs≥1hr: 94%

    Multimirror is a minimal grid-based puzzle game.

    Why similar: Casual 67%, Indie 33%

  6. #6 Dexodonex
    94% matchVery Positive84% of 215 reviews2016
    Dev: Volens Nolens Games
    Windows
    Median: 3.1 hrsMean: 4.0 hrs≥1hr: 84%

    Hexagonal puzzle with the ability to edit levels

    Why similar: Casual 88.2%, Indie 11.8%

  7. #7 Estiman: Game of Estimation
    93% matchVery Positive84% of 57 reviews2016
    Dev: Kool2Play
    Windows
    Median: 3.5 hrsMean: 4.2 hrs≥1hr: 96%

    ESTIMAN is a relaxing arcade game with original estimation-based gameplay

    Why similar: Indie 56.6%, Casual 43.4%

  8. #8 OXXO
    91% matchVery Positive95% of 286 reviews2019
    Dev: Hamster On Coke Games
    Windows · Mac · Linux
    Median: 2.6 hrsMean: 4.3 hrs≥1hr: 85%

    Ever evolving puzzle game.

    Why similar: Casual 76.6%, Indie 23.4%

  9. #9 Supesu
    92% matchVery Positive80% of 50 reviews2018
    Dev: Growfall Games
    Windows

    Welcome to Supesu. Relaxing dimensional puzzle game.

    Why similar: Casual 75.8%, Indie 24.2%

  10. #10 Shoot. Push. Repeat.
    91% matchVery Positive85% of 72 reviews2020
    Dev: CrewLab
    Windows

    A dynamic clicker puzzle simulating real physics.

    Why similar: Casual 76.3%, Indie 23.7%

  11. #11 Inline
    90% matchVery Positive95% of 120 reviews2018
    Dev: Light Bringer Games inc.
    Windows · Mac · Linux
    Median: 2.6 hrsMean: 4.8 hrs≥1hr: 61%

    Inline is an atmospheric, relaxing and minimalist experience reminiscent of classic puzzle games. Arrange the shapes you are given on a grid to form and clear as many lines as possible in this simple yet challenging game.

    Why similar: Casual 79.3%, Indie 20.7%

  12. #12 CrossCells
    89% matchVery Positive83% of 887 reviews2017
    Dev: Matthew Brown
    Windows · Mac · Linux
    Median: 1.9 hrsMean: 3.0 hrs≥1hr: 63%

    CrossCells is an ambient logic puzzle game.

    Why similar: Casual 76.4%, Indie 23.6%

  13. #13 Auto Cell: Game of Life
    89% matchVery Positive87% of 63 reviews2021
    Dev: 日辰星火
    Windows

    Auto Cell run in a two-dimensional grid world. Each grid can be regarded as a small life. It has two states: survival or death.

    Why similar: Casual 100%

  14. #14 Square Logic
    87% matchVery Positive97% of 76 reviews2023
    Dev: Climbing Goat Games
    Windows · Linux

    Square Logic is a minimalist puzzle game about coloring the grid with squares and rectangles, respecting the number of each cell.

    Why similar: Casual 100%

  15. #15 TRIOS - lofi beats / numbers to chill to
    88% matchVery Positive92% of 50 reviews2021
    Dev: Samurai Punk
    Windows · Mac · Linux

    TRIOS is a relaxing, minimalist maths puzzle game. Take your time, chill out with some numbers. Deceptively simple, surprisingly challenging.

    Why similar: Casual 85.6%, Indie 14.4%

  16. #16 LOOP: A Tranquil Puzzle Game
    86% matchVery Positive97% of 136 reviews2015
    Dev: John Cullen
    Windows · Mac · Linux

    LOOP is a tranquil puzzle game, with a unique, simple, meditative feel. Inspired by Zen philosophy, the minimal UI has no timers, move limit or score; allowing you to just relax and focus. Includes over 1 BILLION Levels.

    Why similar: Casual 76.5%, Indie 23.5%

  17. #17 Sorting Inc
    82% matchVery Positive97% of 62 reviews2025
    Dev: AstroTechnician
    Windows · Linux

    A casual and relaxing game about sorting various items. Join Sorting Inc and climb up through the departments to become the absolute expert in the field of sorting.

    Why similar: Casual 74.5%, Indie 25.5%

  18. #18 Atomic Reconstruction
    86% matchMostly Positive77% of 60 reviews2016
    Dev: Teawork Dev
    Windows · Linux
    Median: 3.3 hrsMean: 4.9 hrs≥1hr: 76%

    Atomic Reconstruction is a atmospheric Puzzle game, where you have to use the power of fusion and fission to create and modify specific atoms or groups of atoms.

    Why similar: Casual 75.2%, Indie 24.8%

  19. #19 hocus 2
    84% matchVery Positive86% of 70 reviews2021
    Dev: Yunus Ayyildiz
    Windows · Mac

    ■■■■■■■..........º.......º......º.......

    Why similar: Casual 90.5%, Indie 9.5%

  20. #20 Zen of Sudoku
    85% matchVery Positive89% of 359 reviews2006
    Dev: Unknown Worlds Entertainment
    Windows
    Median: 1.5 hrsMean: 72.2 hrs≥1hr: 60%

    From the creators of Natural Selection comes Zen of Sudoku, a relaxing, easy to play version of Sudoku for your PC.Relax with hand-painted Japanese-styled backgrounds, no timer and lush natural soundscapes.Stimulates your brain to keep it healthy and alert.

    Why similar: Casual 79.6%, Indie 20.4%

  21. #21 Swapperoo
    84% matchVery Positive92% of 78 reviews2015
    Dev: Fallen Tree Games Ltd
    Windows
    Median: 3.0 hrsMean: 3.9 hrs≥1hr: 92%

    The friendly puzzle game intent on your defeat.

    Why similar: Casual 75.8%, Indie 24.2%

  22. #22 Unitied
    82% matchVery Positive98% of 53 reviews2019
    Dev: Peter Hijma
    Windows · Mac · Linux

    Unitied is a minimalistic & relaxing puzzle game

    Why similar: Casual 76.3%, Indie 23.7%

  23. #23 Mega Mosaic
    79% matchVery Positive93% of 342 reviews2024
    Dev: Mark FfrenchPub: Divide The Plunder
    Windows · Mac
    Median: 26.5 hrsMean: 26.3 hrs≥1hr: 88%

    Mega Mosaic is a meditative game about completing a single enormous puzzle

    Why similar: Casual 100%

  24. #24 Meta Sudoku
    79% matchVery Positive83% of 75 reviews2023
    Dev: Matrix Science
    Windows

    Meta Sudoku is a minimalist game, fresh interface and quiet music is very suitable for relaxation, reduce fatigue, give you the most comfortable experience.

    Why similar: Casual 100%

  25. #25 ClickCells: CPU girls
    81% matchVery Positive90% of 98 reviews2020
    Dev: Crew Lab
    Windows

    A casual clicker puzzle simulating real physics.

    Why similar: Casual 75.6%, Indie 24.4%

  26. #26 Jacob
    83% matchMostly Negative36% of 102 reviews2016
    Dev: Duck Duck ZeusPub: Centre For Longitudinal Studies
    Windows

    Jacob: an evidence-based puzzle

    Why similar: Casual 74.1%, Indie 25.9%

  27. #27 Linked
    80% matchVery Positive91% of 583 reviews2017
    Dev: ThinkOfGamesPub: Conglomerate 5
    Windows
    Median: 3.0 hrsMean: 18.9 hrs≥1hr: 83%

    Relaxing, minimalistic 2d-puzzle game.

    Why similar: Casual 70%, Indie 30%

  28. #28 Circularity
    81% matchMixed61% of 64 reviews2017
    Dev: Giorgi AbelashviliPub: SA Industry
    Windows · Mac · Linux
    Median: 36 minMean: 8.5 hrs≥1hr: 42%

    Relaxing puzzle with interesting game mechanics - bring your character to the final portal which will transit you to the next level. You will need to move straight, avoid obstacles, jump through portals, ricochet from walls and a lot more.

    Why similar: Casual 75.8%, Indie 24.2%

  29. #29 808s&Genetics
    77% matchVery Positive97% of 78 reviews2023
    Dev: Magnesiumteng Machine
    Windows

    A puzzle game that combines nonogram and genetics rules.

    Why similar: Casual 88.6%, Indie 11.4%

  30. #30 Quell
    78% matchVery Positive98% of 448 reviews2015
    Dev: Fallen Tree Games LtdPub: Green Man Gaming Publishing
    Windows
    Median: 2.2 hrsMean: 7.9 hrs≥1hr: 69%

    An enchanting game of logic and relaxation.

    Why similar: Casual 67.6%, Indie 32.4%

  31. #31 PEG
    78% matchVery Positive92% of 242 reviews2017
    Dev: Arzola's
    Windows · Mac · Linux
    Median: 3.0 hrsMean: 4.8 hrs≥1hr: 85%

    Blue eats blue. Red eats red. Until one of each remains. A puzzler that is deceptively simple but hard to master.

    Why similar: Casual 75.8%, Indie 24.2%

  32. #32 Delete
    75% matchOverwhelmingly Positive96% of 1,648 reviews2018
    Dev: PONY
    Windows · Mac
    Median: 2.7 hrsMean: 63.2 hrs≥1hr: 79%

    Let the number tell you what to do

    Why similar: Casual 77.5%, Indie 22.5%

  33. #33 Chicken Labyrinth Puzzles
    77% matchMixed68% of 228 reviews2018
    Dev: ZemunBREPub: SA Industry
    Windows
    Median: 2.8 hrsMean: 3.4 hrs≥1hr: 86%

    Guide the lost chicken through mazes and solve puzzles to get home.

    Why similar: Casual 82.7%, Indie 17.3%

  34. #34 My Sudoku
    73% matchMostly Positive76% of 85 reviews2024
    Dev: Dr. Cyril Splutterworth
    Windows

    Beginners, casual players and experts will find an enjoyable challenge in My Sudoku. Solve puzzles at your own pace in a pleasant and relaxing atmosphere.

    Why similar: Casual 100%

  35. #35 Quell Reflect
    76% matchVery Positive95% of 188 reviews2015
    Dev: Fallen Tree Games LtdPub: Green Man Gaming Publishing
    Windows
    Median: 1.8 hrsMean: 8.7 hrs≥1hr: 66%

    An enchanting puzzle game of logic and relaxation.

    Why similar: Casual 65.5%, Indie 34.5%

  36. #36 Quell Memento
    76% matchVery Positive96% of 225 reviews2015
    Dev: Fallen Tree Games LtdPub: Green Man Gaming Publishing
    Windows
    Median: 3.2 hrsMean: 9.4 hrs≥1hr: 71%

    An enchanting puzzle game of logic and relaxation.

    Why similar: Casual 60.4%, Indie 39.6%

  37. #37 Colors!
    74% matchVery Positive84% of 94 reviews2021
    Dev: Vergiu
    Windows

    Minimalist and intuitive puzzle game with relaxing music.

    Why similar: Casual 70.3%, Indie 29.7%

  38. #38 Astra Ignota
    70% matchVery Positive94% of 54 reviews2025
    Dev: Xavi Artigas
    Windows

    A relaxing, space-themed puzzle game where you fill a board using symmetrical figures, while uncovering a mysterious sci-fi story. All boards are hand-crafted for maximum enjoyment.

    Why similar: Casual 100%

  39. #39 Lines Infinite
    74% matchVery Positive92% of 580 reviews2017
    Dev: KonstructorsPub: Hook Games
    Windows · Mac · Linux
    Median: 2.0 hrsMean: 3.4 hrs≥1hr: 63%

    Beautiful & relaxing Numberlink puzzles.

    Why similar: Casual 76.7%, Indie 23.3%

  40. #40 Hex
    75% matchVery Positive88% of 57 reviews2017
    Dev: Studio Goya
    Windows · Mac

    Hex is a unique puzzle game with a simple goal, clear the tiles to win. Tiles might multiply, explode, toggle on and off, and more as you jump between them in this exciting journey through over 80 challenging levels.

    Why similar: Casual 56.3%, Indie 43.7%

  41. #41 Wayout
    73% matchVery Positive88% of 1,173 reviews2016
    Dev: KonstructorsPub: Hook Games
    Windows · Mac · Linux
    Median: 2.8 hrsMean: 7.5 hrs≥1hr: 78%

    Relax, clear your mind and find the way out.

    Why similar: Casual 73.4%, Indie 26.6%

  42. #42 Puzzle - LINES AND KNOTS
    72% matchVery Positive87% of 260 reviews2020
    Dev: PlayToday
    Windows

    Logical puzzle game for meditation. The goal of the player is to assemble a puzzle consisting of nodes. Easy to understand mechanics, swap hexagons with lines.

    Why similar: Casual 79.1%, Indie 20.9%

  43. #43 Microcosmum: survival of cells
    71% matchVery Positive83% of 1,412 reviews2015
    Dev: Satur Entertainment
    Windows
    Median: 3.4 hrsMean: 5.4 hrs≥1hr: 92%

    Microcosmum: survival of cells. Join the wonderful and amazing world of microorganisms.

    Why similar: Casual 100%

  44. #44 Bombe
    67% matchVery Positive96% of 371 reviews2023
    Dev: Charlie Brej
    Windows · Mac · Linux

    Minesweeper, but you only solve each situation once.

    Why similar: Casual 100%

  45. #45 Puzzle Car
    70% matchVery Positive95% of 102 reviews2021
    Dev: Rising Moon Games
    Windows · Linux

    A minimalist and relaxing experience. Challenge yourself to move pieces to assemble a safe path for your car and collect all the items on the way, while listening to a relaxing soundtrack in a totally minimalist environment.

    Why similar: Casual 81.2%, Indie 18.8%

  46. #46 ClickCells: Winter Lady
    71% matchVery Positive87% of 59 reviews2020
    Dev: Crew Lab
    Windows

    Erotic casual puzzle!

    Why similar: Casual 76.1%, Indie 23.9%

  47. #47 Cozy Sudoku
    66% matchVery Positive80% of 141 reviews2024
    Dev: CozyPuzzleGames
    Windows · Linux

    Sudoku, tunes, and some furry friends.

    Why similar: Casual 81.1%, Indie 18.9%

  48. #48 Lines X
    70% matchVery Positive82% of 972 reviews2017
    Dev: KonstructorsPub: Hook Games
    Windows · Mac · Linux
    Median: 1.3 hrsMean: 28.9 hrs≥1hr: 58%

    Beautiful & relaxing Numberlink puzzles.

    Why similar: Casual 78.9%, Indie 21.1%

  49. #49 Perfection.
    73% matchMostly Negative39% of 66 reviews2013
    Dev: Greg Lobanov
    Windows · Mac
    Median: 6 minMean: 10.1 hrs≥1hr: 13%

    Perfection. is a simple, soothing puzzle game about cutting shapes to fit into outlines. There are an infinite number of puzzles, each randomly generated to be unique and interesting.Its gameplay is very minimalistic and very forgiving; there is no time limit, and you can cut as many times as you want and undo as many times as you want...

    Why similar: Casual 77.7%, Indie 22.3%

  50. #50 Puzzle Galaxies
    71% matchMixed59% of 176 reviews2016
    Dev: Evermore Game StudiosPub: Sometimes You
    Windows · Mac
    Median: 3.3 hrsMean: 3.5 hrs≥1hr: 90%

    Puzzle Galaxies is a groundbreaking puzzle video game similar to games like Bejeweled and Candy Crush. You must match jewels stored in a space station in a manner similar to Bejeweled, but there's a twist - there are enemies that will come by and try to take matching jewels on you!

    Why similar: Casual 62.6%, Indie 37.4%

  51. #51 Hexcells Infinite
    68% matchOverwhelmingly Positive97% of 4,629 reviews2014
    Dev: Matthew Brown
    Windows · Mac · Linux
    Median: 6.8 hrsMean: 36.0 hrs≥1hr: 78%

    Hexcells Infinite is an ambient logic puzzle game for PC, Mac and Linux.

    Why similar: Casual 78.9%, Indie 21.1%

  52. #52 Sandtrix+
    66% matchVery Positive93% of 152 reviews2023
    Dev: msky
    Windows · Mac · Linux

    Retro Falling Sand Puzzle Game

    Why similar: Casual 74.8%, Indie 25.2%

  53. #53 Hexcells
    67% matchOverwhelmingly Positive97% of 5,865 reviews2014
    Dev: Matthew Brown
    Windows · Mac · Linux
    Median: 2.1 hrsMean: 4.7 hrs≥1hr: 70%

    Hexcells is an ambient logic puzzle game for PC, Mac and Linux.

    Why similar: Casual 78.7%, Indie 21.3%

  54. #54 LYSER
    69% matchVery Positive90% of 84 reviews2019
    Dev: Growfall Games
    Windows

    Casual puzzle with laser reflections.

    Why similar: Casual 75.8%, Indie 24.2%

  55. #55 THE ART - Metamorphosis
    68% matchVery Positive91% of 80 reviews2020
    Dev: Life Jumb DTPub: Red twice potato
    Windows

    THE ART is a puzzle game where you have to arrange the fragments of the picture in the correct sequence.

    Why similar: Casual 76.3%, Indie 23.7%

  56. #56 Strata
    69% matchVery Positive87% of 360 reviews2014
    Dev: GraveckPub: GLITCH
    Windows · Mac · Linux
    Median: 1.1 hrsMean: 3.7 hrs≥1hr: 52%

    Simple. Elegant. Challenging.

    Why similar: Casual 78.7%, Indie 21.3%

  57. #57 No.9
    64% matchVery Positive89% of 102 reviews2024
    Dev: Maciej Targoni
    Windows · Mac · Linux

    Synchronizing form and time.

    Why similar: Casual 82%, Indie 18%

  58. #58 Pure Logic
    65% matchVery Positive93% of 91 reviews2023
    Dev: Sigmund Hoien
    Windows

    Explore logic symbols. Discover the rules. Solve complex puzzles. Feel the power of your logical side!

    Why similar: Casual 79.8%, Indie 20.2%

  59. #59 Energy Balance
    69% matchMixed69% of 322 reviews2015
    Dev: Sometimes You
    Windows · Mac · Linux
    Median: 4.2 hrsMean: 5.9 hrs≥1hr: 98%

    Energy Balance is a number puzzle. You have to swap power units in such a way that their sums form correct chains both vertically and horizontally. The game is easy to learn, but very hard to master. So, are you ready to peep under the hood of an alien spaceship?

    Why similar: Casual 52.5%, Indie 47.5%

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Games Like Bacteria

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