Games Like Bioprototype

The engineering roguelike. Construct your combos by wiring circuits. Build crazy machines to zap the monsters and trigger satisfying chain reactions. Discover devastating synergies and create overpowered builds.

Why similar: Programming 32.4% ★, Deckbuilding 18.7%, Automation 14%, Roguelike 9.4%, Roguelite 8.7%

Why You'll Like It: Features a complex, system-based approach to combat where you must program and chain abilities to survive.

Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.

Why similar: Bullet Hell 24.1%, Roguelike 17.9%, Action Roguelike 15.9%, Roguelite 14.2%, Hack and Slash 14%

Why You'll Like It: Offers deep tactical build-crafting and character customization that mirrors the complexity of Bioprototype's organ-linking system.

"Magicraft" is a Roguelike game that uses a variety of spells to match unimaginable spell effects, and the construction of ultra-high degrees of freedom cannot even be exhausted by developers.

Why similar: Bullet Hell 24.7%, Deckbuilding 21.4%, Roguelite 17.9%, Action Roguelike 17.4%, Roguelike 14.1%

Why You'll Like It: Focuses heavily on spell-crafting and customization, allowing players to build unique magical synergies similar to organ mutations.

Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!

Why similar: Vampires 30.7% ★, Bullet Hell 22%, Action Roguelike 16.7%, Roguelite 12.6%, Pixel Graphics 6.6%

Why You'll Like It: The definitive genre-defining experience that established the core loop of surviving endless waves of enemies.

Bioweaver is an RPG game with the main content of treasure hunting and character building. You can use basic programming logic to deeply customize your skill sets, and you can also create organs with different attributes and functions with the special crafting system.

Why similar: Programming 28.8% ★, Tactical RPG 13.6%, Deckbuilding 11.8%, Bullet Hell 10.9%, Hack and Slash 9%

Why You'll Like It: Shares a strong thematic and mechanical focus on biological customization and tactical action-RPG elements.

20 Minutes Till Dawn is a survival roguelite where endless hordes of creatures lurk from the dark. Craft an array of overpowering builds and eradicate waves of Lovecraftian nightmares. Will you be able to survive the night?

Why similar: Bullet Hell 32.8%, Action Roguelike 23.7%, Roguelite 21.2%, Pixel Graphics 10.7%, Strategy 6.9%

Why You'll Like It: Combines high-intensity bullet-hell action with a robust upgrade system that rewards strategic build choices.

Amass an army of undead to fight endless waves of heroes intent to end your boneraising ways! In this gothic auto-battler rogue-lite Survivor-like, use the bones of slain heroes to raise your minions, collect relics and spells, and unlock meta upgrades, all to survive King Gigald's crusade!

Why similar: Vampires 34.3% ★, Bullet Hell 18.1%, Action Roguelike 12.6%, Roguelite 12.4%, Roguelike 8.5%

Why You'll Like It: A unique take on the survivor genre that focuses on raising and customizing your own army of minions.

A roguelike where you automate combat. Combine skills and conditions to find your own optimal solution! No complicated controls at all!! Sit back with a coffee and watch the beautiful battles you've crafted unfold! Utilize a variety of skills, conditions, and relics to craft the ultimate build!

Why similar: Programming 39% ★, Automation 14.2%, Auto Battler 12.9%, Roguelike 10.8%, Roguelite 9.7%

Why You'll Like It: Emphasizes automation and strategic planning, perfect for players who enjoy the programming aspect of Bioprototype.

Face the Lords of the Void and their endless minions, collect their Soulstones and become a god! In this Action Roguelite, unveil secret spells, craft mighty weapons, unlock multiple characters, discover game-breaking synergies and conquer the power of the void.

Why similar: Bullet Hell 25.4%, Hack and Slash 18.9%, Action Roguelike 18.3%, Roguelite 17.8%, Roguelike 15.4%

Why You'll Like It: Provides a massive skill tree and deep build variety that allows for highly specialized character progression.

Descend the nether in search of Death himself! Choose from God-given powers to slay his hordes of minions. Unlock new heroes, collect powerful items and create game-breaking synergies in this roguelite hack and slash survivors game.

Why similar: Bullet Hell 24.5%, Action Roguelike 17.1%, Roguelite 17.1%, Hack and Slash 15.8%, Roguelike 10.7%

Why You'll Like It: Blends classic action-roguelite gameplay with RPG-lite gear and skill systems that emphasize build synergy.

Noita is a magical action roguelite set in a world where every pixel is physically simulated. Fight, explore, melt, burn, freeze and evaporate your way through the procedurally generated world using spells you've created yourself.

Why similar: Roguelike 25.9%, Action Roguelike 19%, Roguelite 18.3%, Pixel Graphics 15.7%, Difficult 8%

Why You'll Like It: The ultimate game for players who love 'programming' their own destruction through complex, physics-based wand building.

Battle against hordes of enemies, conquer Boss encounters, and explore various character and skill combinations in this time-based auto-attacking Roguelite in your quest to become stronger and defeat the most menacing of creatures that lay in wait at the end of each run.

Why similar: Bullet Hell 20%, Auto Battler 15.4%, Deckbuilding 14.6%, Roguelite 14.1%, Action Roguelike 14.1%

Why You'll Like It: A classic entry in the genre that provides a straightforward but highly addictive loop of character growth.

Build a powerful deck, cast spells on the fly, battle evolving enemies, find game-changing artifacts, make friends or make enemies, just make it to Eden.

Why similar: Deckbuilding 19.9%, Bullet Hell 15.2%, Roguelite 12.8%, Action Roguelike 12.3%, Hack and Slash 10.6%

Why You'll Like It: Offers fast-paced, deckbuilding-focused combat that requires quick thinking and strategic card synergy.

Nordic Ashes: Survivors of Ragnarok, is a challenging Norse inspired roguelite-survivor game, where you’ll have to survive hordes of creatures that come your way.

Why similar: Bullet Hell 29.2%, Roguelite 20.2%, Action Roguelike 20%, Roguelike 16.4%, Strategy 6.6%

Why You'll Like It: Features a unique skill tree system that allows for deep customization of your character's abilities as you survive.

An action roguelite game with alien swarms and mechs. Battle enemies to make your way through a mass of spreading and evolving cells hosting dormant enemies. Collect a variety of game-changing skills and upgrades to create unique builds.

Why similar: Bullet Hell 25.4%, Roguelite 18.7%, Action Roguelike 17.3%, Roguelike 17%, Pixel Graphics 8.5%

Why You'll Like It: An action-roguelite that blends bullet-hell combat with unique map-clearing and progression mechanics.

Centipede Gun is a roguelite autobattler where you create bizzare creatures to face hordes of enemies! Combine different guns, modules and skills to make unique synergies and upgrade your cute little destruction machine!

Why similar: Bullet Hell 23%, Auto Battler 17.1%, Roguelite 16.6%, Action Roguelike 15.3%, Deckbuilding 12.6%

Why You'll Like It: Features intense bullet-hell action with a focus on weapon customization and roguelite progression.

Play as your favorite Vtubers from Hololive! Fight, explore, and clear your way through armies of fans and save them from their mind-control in this unofficial free fan-game.

Why similar: Bullet Hell 33.2%, Action Roguelike 22.1%, Roguelite 20.8%, Pixel Graphics 14.7%, 2D 4.6%

Why You'll Like It: A highly polished survivor-like that features deep weapon-merging mechanics and character-specific synergies.

Slay endless hordes of demons to protect the Cosmic Library! Steal their abilities, find powerful equipment, and unlock the secrets of each spellbook to become unstoppable! Will you be able to destroy the demonic legion?

Why similar: Bullet Hell 27%, Roguelite 18%, Action Roguelike 17.7%, Roguelike 15.6%, Pixel Graphics 11.9%

Why You'll Like It: Focuses on spell-based combat with a heavy emphasis on stacking modifiers to create powerful, screen-clearing builds.

A roguelike tower defense where you control a single tower to fight against hordes of aliens coming from all directions. Pick your tower, equip up to 4 skills, and choose from a variety of traits and unique effect items to craft powerful builds that lead you to victory.

Why similar: Deckbuilding 19.8%, Bullet Hell 18.7%, Auto Battler 17.7%, Action Roguelike 14.4%, Roguelite 13.9%

Why You'll Like It: Blends tower defense mechanics with survivor-like action, requiring careful placement and build synergy.

Wreak havoc on countless foes with mighty weapons and deadly spells! Enhance your skills and face even greater dangers! Army of Ruin is an auto-shooter where you become the Bullet Hell.

Why similar: Bullet Hell 26.9%, Hack and Slash 19.8%, Action Roguelike 18.2%, Roguelite 17.4%, Roguelike 15%

Why You'll Like It: A high-quality bullet-hell survivor that excels at providing satisfying visual feedback and diverse build paths.

In this tactical rogue-like auto battler, you'll build your unique team of robots and keep them alive as they fight. Battle through waves of enemies as you travel from planet to planet on a mission to fix the sun. Strategize, protect, survive. A Mechanibot's wrench never rests.

Why similar: Deckbuilding 21.1%, Auto Battler 20.8%, Action Roguelike 15.9%, Roguelite 15%, Roguelike 12.1%

Why You'll Like It: A tactical auto-battler that rewards players for building and managing a team of specialized units.

All heroes got corrupted! Unlock a diverse cast of crafty professionals, use their unique skills, create your own builds and defend your home by eliminating hordes of monsters. Gather materials, rebuild your village and craft your way to the origin of this malignous curse!

Why similar: Bullet Hell 26.4%, Roguelite 20.7%, Action Roguelike 19.8%, Roguelike 17.8%, Pixel Graphics 9.5%

Why You'll Like It: Integrates crafting and progression systems into the survivor loop, rewarding players for thoughtful build planning.

Burst Hero is a pixel roguelike shooting survival game. You can choose heroes with different abilities and use various weapons to resist a steady stream of enemies. In the battle, you can customize your build by weapons bullets and cards. Each battle will have different experiences and challenges.

Why similar: Bullet Hell 20.5%, Vampires 16.8% ★, Auto Battler 16%, Deckbuilding 14.1%, Roguelite 13.9%

Why You'll Like It: A twin-stick shooter that incorporates roguelite elements and bullet-hell intensity for a challenging experience.

CODE OR DIE! Hack enemy systems & survive the security response by engineering lethal bullet-heaven algorithms. Your brain power determines your firepower across 190+ programming nodes. Debug your failures. Optimize your code. Complete the heist. HACK THE PLANET!

Why similar: Programming 46.5% ★, Bullet Hell 16.5%, Roguelite 10.7%, Action Roguelike 10.3%, Sci-fi 5.2%

Why You'll Like It: Directly appeals to the programming and logic-based interests of players who enjoy the technical side of Bioprototype.

Splatter slimes, massacre mutants, and assemble your perfect Gunbot! Survive the wasteland in this top-down shooter roguelite by customizing your weapons on the unique upgrade grid, and pick from tons of build-defining modules and wacky bots for a new experience every run. Prologue teaser build.

Why similar: Bullet Hell 33%, Action Roguelike 21.2%, Roguelite 19.5%, Roguelike 13.5%, Action 4.5%

Why You'll Like It: Focuses on gun-customization and tactical shooting, appealing to those who enjoy tinkering with their loadouts.

A rogue-lite game where you must face hundreds of monsters with increasingly difficult bosses that strong enough to take you down. Choose your abilities, build your favorite combat style, become stronger and survive as long as you can!

Why similar: Bullet Hell 24.2%, Roguelike 19.2%, Roguelite 17.9%, Action Roguelike 17.5%, Pixel Graphics 11.5%

Why You'll Like It: Provides a classic pixel-art aesthetic combined with the satisfying progression loop of the survivor genre.

Design your defenses, build your module board, and manage your wires. Combine signals and create synergies to empower your weapons and survive in this base-defense roguelike auto-battler.

Why similar: Programming 31.3% ★, Deckbuilding 14.7%, Auto Battler 14.1%, Automation 14.1%, Roguelite 8%

Blast hordes of alien ships into junk. Collect the scrap to upgrade your ship into an unstoppable force of destruction. Unlock new characters and weapons and upgrade your stats between runs.

Why similar: Bullet Hell 24.7%, Action Roguelike 23%, Roguelite 19.9%, Roguelike 16.7%, Sci-fi 8.1%

Why You'll Like It: A fast-paced bullet-hell survivor that focuses on chaotic, high-speed combat and weapon upgrades.

Deckbuilding empowers this challenging bullet hell adventure! Each character is a unique experience: Choose a deck of unlockable cards to boost you in new ways every battle - "My whirlwind shoots fireballs!?". Battle hordes of brutal foes to become a superstar in C-SAR’s ever-changing game show.

Why similar: Deckbuilding 21.4%, Bullet Hell 18.5%, Action Roguelike 13.7%, Roguelite 12.4%, Hack and Slash 11.6%

Why You'll Like It: Combines action-roguelite combat with deckbuilding elements to create a unique tactical challenge.

Craft Your Ultimate Circular Fortress! Dive into SHOOPER NOVA, where you choose props and components to build a unique fortress. Unlock combos to shape your strategy and battle style. Become an unstoppable barrage machine and obliterate waves of enemies from all directions!

Why similar: Bullet Hell 23.5%, Roguelite 20.3%, Action Roguelike 13.1%, Roguelike 10.7%, Deckbuilding 9.7%

Demolish hordes of enemies and survive against all odds! Unlock different characters, find powerful skill combinations and embark on an exciting journey through the variety of very different worlds in this cute but unforgiving roguelike game!

Why similar: Vampires 47.2% ★, Action Roguelike 17.2%, Roguelite 17%, Roguelike 12%, 2D 3.1%

Why You'll Like It: A solid vampire-like experience that emphasizes arena-based survival and character-specific builds.

Annihilate hordes of enemies in this thrilling, fast-paced action roguelite rpg and fill the screen with your magic. Kill your foes, become stronger each second and upgrade your characters with new spells and abilities. Can you survive the monsters that threaten your very existence?

Why similar: Vampires 23.8% ★, Bullet Hell 22.5%, Action Roguelike 15.8%, Roguelite 11.8%, Roguelike 11.4%

Why You'll Like It: A spell-focused survivor-like that emphasizes score-attack mechanics and magical build variety.

Blast through robotic hordes in this arena auto-battler rogue-lite Brotato-like. Use auto-firing weapons and drones, timely dashes and special abilities to reach the Void where a final Conservator awaits convergence. Spend your Cogs wisely within the varied shops to create unique builds!

Why similar: Bullet Hell 22.4%, Hack and Slash 16.6%, Action Roguelike 15.9%, Roguelike 15.1%, Roguelite 15%

Bullet Heaven x Endless Loot! Create Your Own Build in this Roguelite Action RPG.

Why similar: Bullet Hell 25.2%, Action Roguelike 17.4%, Roguelite 17.4%, Hack and Slash 16.8%, Roguelike 14.8%

Archons is a Roguelite/Survivor game where you control two characters, the Archons- simultaneously! Customize your build and abilities to fit your own unique playstyle and blast your way through enemy parasites and bosses!

Why similar: Bullet Hell 20.1%, Deckbuilding 15.9%, Hack and Slash 15.7%, Roguelite 13.7%, Action Roguelike 13.7%

Embark on an epic saga in Asgard's Fall, a norse Survivors-like Roguelite. Fight your way through hordes of creatures and let the gods feel your relentless wrath. How will your saga unfold?

Why similar: Vampires 22.8% ★, Bullet Hell 17%, Roguelite 11.8%, Action Roguelike 11.4%, Hack and Slash 11.3%

The AUTOMATION bullet heaven! Build your custom spellcasting factory and tear through endless waves of monsters. Unlock 20+ characters and 100+ golden totems to craft broken roguelite synergies and survive the swarm! Build, automate, autocast, OBLITERATE!

Why similar: Automation 29.4%, Action Roguelike 21.4%, Roguelite 17.6%, Roguelike 13.9%, Pixel Graphics 11.7%

Arcane Trigger is a bullet-building roguelike where every shot is crafted before it's fired. Forge over 220 bullets, shape their effects with 150+ magical seals, and master infinite synergies in this endlessly replayable strategic shooter.

Why similar: Roguelite 22.2%, Auto Battler 20.1%, Roguelike 18.3%, Pixel Graphics 11.5%, Deckbuilding 9.8%

Salvo Shuffle is a bullet-hell roguelike that mixes turn-based and action-based combat.

Why similar: Deckbuilding 27.6%, Bullet Hell 25.5%, Action Roguelike 17.3%, Roguelite 9.5%, Strategy 6.9%

A mini topdown action roguelike with chaotic spell-slinging hack-n-slash combat. Collect spells, choose perks and discover powerful synergies to become an unstoppable monster-slaying wizard.

Why similar: Action Roguelike 31.6%, Roguelite 27.3%, Roguelike 19.3%, Pixel Graphics 8.4%, Action 5.4%

Adapt your strategy to a skill tree that changes every run, combine pieces of equipment to form powerful synergies and create a game-changing build capable of defeating the bosses that will try to stop you. In this Inventory Management Roguelike two games never feel the same!

Why similar: Roguelite 26.2%, Roguelike 20.4%, Auto Battler 17.6%, Deckbuilding 16.5%, Pixel Graphics 12.7%

Bronana is a thrilling and hilarious survival roguelike. Embody the spirit of a fearless banana warrior to take down waves of vicious snack monsters. Through a rich variety of random events, grow stronger, evolve abilities, and face off against challenging bosses to save the homeland.

Why similar: Vampires 32.2% ★, Bullet Hell 19.4%, Roguelite 13.3%, Action Roguelike 13.1%, Roguelike 11.7%

Walk upon a new world and slay foes endangering it. Rogue : Genesia is an action rogue-lite game, where you fight relentless hordes consisting of hundreds and thousands of monsters, make your build, break the balance, defeat bosses and save one of the many worlds.

Why similar: Bullet Hell 29.3%, Roguelite 19.8%, Action Roguelike 19.3%, Roguelike 13.8%, Pixel Graphics 6.1%

Slay never-ending legions of monsters while running in circles! SuperTotalCarnage! is a gory and dark horror casual game with rogue-lite elements. Choose from a variety of weapons and perks and make every playthrough a different experience. Unlock many characters each one with different abilities.

Why similar: Bullet Hell 23.8%, Vampires 17.6% ★, Action Roguelike 17.1%, Roguelite 15.7%, Auto Battler 9.5%

You are the first party mech pilot of alien planet colonizers! Project Lazarus is a survival game with rogue-lite elements. Deploy and upgrade your mech to the metal!

Why similar: Bullet Hell 46%, Action Roguelike 36.9%, Sci-fi 9.9%, Action 6.3%, Singleplayer 0.9%

Disfigure is a grim-dark action rogue-like where you battle relentless hordes of monsters lurking in the shadows. Unlock powerful weapons, craft god-like builds with hundreds of upgrades, slay colossal bosses, and push your limits in intense 20–30 minute survival runs!

Why similar: Bullet Hell 30%, Action Roguelike 20%, Roguelite 15.4%, Roguelike 15.4%, Pixel Graphics 8.7%

A pixel-art action roguelike with dynamic combat, player-led combo crafting and a post-apocalyptic battle of wolf and lamb. Step into the shoes of the robot-sheep Omega to wield sci-fi weapons and gather evolving skills to protect your flock. Jump into the loop and create a unique combat style.

Why similar: Deckbuilding 23.7%, Hack and Slash 17.2%, Action Roguelike 15.8%, Roguelite 14.8%, Roguelike 12.8%

Battle and survive hordes of monsters in this high octane casual game with rogue-lite elements. Defeat bosses, hot-wire cars and stack powerups. How long will you survive?

Why similar: Bullet Hell 38.7%, Action Roguelike 27.5%, Roguelite 26.2%, Action 5.9%, Indie 1.1%

Survive waves! Choose new abilities! Modify your hero in any way you like! Craft a powerful masterpiece, or a horrible concoction of awful ideas! Discover secrets! Sandbox your way to victory! Boost! Survive! Boosted Survivors!

Why similar: Action Roguelike 44.5%, Roguelike 30%, Pixel Graphics 12.3%, Action 8.4%, Indie 3.6%

Orbital Bullet is a fast paced 360° action-platformer with rogue-lite elements, where all actions take place in a circular pattern. Fight your way through a variety of procedural planets and use body modifications, crafting and heavy weaponry. Kill. Die. Modify.

Why similar: Action Roguelike 22.5%, Roguelike 21.7%, Hack and Slash 15.2%, Pixel Graphics 13.6%, Sci-fi 8.4%

Deckstination is a real-time combat and deck-building hybrid. In this action roguelike, players use customized skill decks to overcome enemies in battles. Combine randomly drawn skills to survive intense encounters and take control of the battlefield with your own actions and strategy.

Why similar: Deckbuilding 40%, Roguelike 15.9%, Action Roguelike 11.3%, Strategy 10.7%, Pixel Graphics 7.8%

Welcome to Slime 3K, an unhinged roguelite bullet-heaven set in the Despot’s Game universe! Build a deck of crazy weapons, grow stronger and devour hordes of pink puny humans as a murderous jelly blob on a warpath of death, violence and pretzels.

Why similar: Deckbuilding 20.8%, Bullet Hell 19.8%, Action Roguelike 13.4%, Roguelite 13.2%, Hack and Slash 12.8%

NET.CRAWL is a grid-building roguelike about a White Rabbit trapped in an unfriendly cyberspace. Dive deep into a bizarre digital world where levels are built with the nodes you drafted. Short runs, satisfying combos, dozens of unique bosses, and a ton of replayability.

Why similar: Programming 31% ★, Deckbuilding 19.5%, Tactical RPG 17.5%, Roguelite 12.6%, Roguelike 10.5%

Survive thousands of monsters in X-Mutation, a hardcore 3D top-down rogue-lite action game. Mutate your body into diverse weapons, choose from hundreds of mutations, and uniquely upgrade to craft your personal combat style!

Why similar: Bullet Hell 25%, Hack and Slash 19.5%, Action Roguelike 18.3%, Roguelite 18.1%, Roguelike 16.4%

Slay waves of spooky enemies for 20 nights to survive 'The Demonic Conveyor Belt'. Talented is an arcade roguelite with randomly generated skill trees. Choose your upgrades and abilities wisely and you might just make it out alive. Are you truly Talented?

Why similar: Action Roguelike 23.2%, Roguelite 22.1%, Roguelike 16.5%, Programming 13.4% ★, Pixel Graphics 12.6%

Survive waves of enemies in this horde survival roguelite. Unleash devastating spells, master unique skills, and craft unstoppable builds. Between battles, fortify your tower and unlock powerful upgrades in a strategic meta-game. Will your magic outlast the chaos?

Why similar: Bullet Hell 27.9%, Roguelite 19.2%, Action Roguelike 18.9%, Roguelike 15.9%, Pixel Graphics 8.7%

Slash and survive a typical workday as Dracula's overworked and underappreciated servant! You'll have a bloody good time as you rampage through New Orleans to find fresh victims for your narcissistic boss.

Why similar: Vampires 34% ★, Bullet Hell 19%, Action Roguelike 13.3%, Roguelite 12.7%, Pixel Graphics 7.2%

A roguelite horde-survival bullet heaven with QUINTILLIONS of bullets over QUINTILLIONS of hordes. Mix weapons with items, modify, control chaos at terminals and break through tightening waves.

Why similar: Bullet Hell 29.9%, Action Roguelike 22.2%, Roguelite 19.7%, Roguelike 15.9%, Sci-fi 11.2%

Miracle Brave blends inventory management, deck-building, tower defense, and shooter combat! Strategize your gear, forge your unique build from countless progression paths, take control of your hero, and hold back endless waves of beasts. Carve out your path to victory and forge your own legend!

Why similar: Bullet Hell 18.7%, Roguelite 15.5%, Deckbuilding 15.4%, Auto Battler 12.8%, Automation 12.5%

Build unique synergy spell combos to destroy the hordes of monsters and bosses in this rogue-lite action game.

Why similar: Hack and Slash 21.2%, Action Roguelike 18.3%, Roguelite 18.2%, Roguelike 14.5%, Bullet Hell 11.7%