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Games Like Plague Doctor: Life in Pestilence

60+ similar titles based on shared tags and player behavior. Themes include Simulation, Singleplayer, Immersive Sim, Management.

Plague Doctor: Life in Pestilence header art

From an unknown quack to a reputable Plague Doctor, watch the plague unfold before your eyes. Gather ingredients, brew remedies, expand your clinic, and perform surgeries alone or up to 4 player co-op. Will you uphold the Hippocratic Oath... or watch the world rot and darken with every death.

Reviews: No user reviews — 50%
Released: Coming soon
Developer: PST Games
Genres: Adventure, Indie, Simulation
Platforms: Windows

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    Windows

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    Why similar: Medical Sim 42%, Management 11.9%, Simulation 10.2%, Economy 8.2%, Immersive Sim 7.4%

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    Dev: Altai Entertainment
    Windows

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    Why similar: Medical Sim 39.9%, Life Sim 12.8%, Immersive Sim 12.7%, Simulation 9.1%, Economy 8%

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    95% matchVery Positive90% of 50,786 reviews2021
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    Windows
    Median: 11.8 hrsMean: 36.2 hrs≥1hr: 91%

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    Why similar: Crafting 14.5%, Building 12.2%, Medieval 10.8%, Co-op 9.2%, Base Building 9%

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    94% matchNo user reviews
    Dev: FrogVille Games
    Windows

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    94% matchNo user reviews
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    Windows

    Store Life Simulator is a simulation and management game where you start with a small grocery store and have to expand it until you create a true business empire! Hire employees, manage your stock, serve customers and open new stores while facing the daily challenges of an entrepreneur.

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    93% matchNo user reviews
    Dev: GamesUP StudioPub: T-Bull
    Windows

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    91% matchNo user reviews2026
    Dev: CozyPlayPub: Polden Publishing
    Windows

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    92% matchVery Positive87% of 1,110 reviews2017
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    Windows · Mac · Linux
    Median: 2.0 hrsMean: 12.6 hrs≥1hr: 62%

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    90% matchNo user reviews
    Dev: SolidGames
    Windows

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  12. #12 Pharma Craft
    88% matchPositive89% of 18 reviews2026
    Dev: ZD Yazilim
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    89% matchMixed48% of 25 reviews2025
    Dev: Prosuntal Games Studio
    Windows

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    89% matchVery Positive92% of 34,521 reviews2018
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    Windows · Mac · Linux
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    87% matchMixed58% of 31 reviews2024
    Dev: Eathrabaria
    Windows

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  16. #16 Blacksmith's Kingdom
    86% matchNo user reviews
    Dev: HinkoStudio
    Windows

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    Windows

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    Windows

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    Windows

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    Windows
    Median: 7.5 hrsMean: 16.3 hrs≥1hr: 86%

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    Windows · Linux

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    Windows

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    Windows

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    72% matchNo user reviews
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    71% matchNo user reviews
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    75% match2 user reviews50% of 2 reviews2021
    Dev: Valley General
    Windows

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    Windows · Mac · Linux

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    69% match8 user reviews63% of 8 reviews2026
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    67% matchMostly Positive71% of 249 reviews2024
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Games Like Plague Doctor: Life in Pestilence

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