Top Outbreak Sim Games

Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.

The post-apocalyptic dark comedy is back - remastered and even more radioactive than before! Scavenge supplies, rescue your family, and stay alive in your fallout shelter. Make difficult decisions, hunt mutant roaches... and maybe survive. Or not.

60 Seconds! is a dark comedy atomic adventure of scavenge and survival. Collect supplies and rescue your family before the nuke hits. Stay alive in your fallout shelter. Make difficult decisions, ration food and hunt mutant cockroaches. And maybe survive. Or not.

A campy, crazy pixelart zombie apocalypse arcade sim where you're the bad guy. Drop your virus and spread it across the globe while you unlock a whole horde of bizarre undead to do your bidding.

Bio Inc.: Redemption is a realistic simulation and strategy game in which you make life or death decisions. Create a deadly illness to infect and torment your victim or play as the head of a medical team and hopefully find a cure to save your human patient. Will you be the plague or preserve humanity?

Quarantine is an intense turn-based strategy game about waging war on pandemic disease. Recruit a team of specialized operatives to deploy on worldwide missions. Research the contagion, upgrade your tech, and quarantine the outbreak before it kills us all.

DeadOS is an early access zombie outbreak simulator by Benn Powell that focuses on city-wide scenarios where you have access to fully customize your apocalypse experience from beginning to end. Simulation. Sandbox. Survival!

ICBM is a real-time strategy game of nuclear destruction. Research new technologies, build up your nuclear stockpile and use a combination of ships, planes and missiles to strike at the heart of your opponents’ cities while keeping your population safe from harm.

Can you rebuild civilization after a zombie apocalypse? From the creator of Plague Inc. comes a unique blend of strategic simulation, survival city builder and ‘mini 4X’. Build post-apocalyptic settlements, harvest resources and shape society as you lead humanity out of the darkness.

Discover a post-apocalyptic world Collect resources and manage people Build your colony on the remains of an oil tanker Prepare supplies and vehicles for a dangerous expedition. Complete challenging tasks from the council of elders

Take on the role of a Dark Elder God and lead your agents to bring about an apocalypse in a fantasy world. Work in the shadows, avoiding the heroes who will try to stop you, as you bring about plague and famine, ice age and volcanic destruction, madness and never ending night.

Manage the night shift of an ER during the apocalypse, solo or with friends online: Diagnose patients. Design and grow your hospital, and defend against the undead while treating the living. If you're a creator, connect the game to Twitch and make the audience your patients for even more fun!

The Fabulous Fear Machine is a narrative-driven strategy game with a pulp horror style. As the Machine's new Master, you must sow fear and expand your influence by creating Legends, harvesting resources, manipulating events, and spying on your enemies.

Will you be able to infect all devices of the world? «Trojan Inc.» - simulator, which will involve you in a world of computer viruses and trojans.

Kill everyone in the world with a guillotine… on a cursed Win98 desktop.

Evil Labs is a game about building and managing your own Evil Laboratory. Research and develop diseases, infect people, sell the cure and get rich!

Become an inspector examining causes of plane crashes. Visit the crash site, gather evidence and interrogate witnesses. Explain whether the accident was caused by independent factors or human errors.

It started in your foot. Now it’s in your head. All that remains is the command: GO UP. Meet strange neighbors. Make bad trades. Every ascent teaches you what you should have done differently.

Join the persistent open world of OZERSK! Choose your way to play on PvE or PvP servers, fight for precious loot and gear, and risk it all in a hostile environment. Die, lose all your gear and loot, then return to the same server in hopes of retrieving what you lost. This is your story!

In the game, day and night alternate. Zombies will not be active during the day, so you can build your home with confidence. But at night you have to resist hordes of zombies and guard your camp!

Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.

Survive the Zombies War in this RPG game of Apocalypse and Survival

War of the Zombie brings together the best of turn-based simulation and real-time strategic gameplay action across the entire world at the very start of a mysterious undead outbreak.

End humanity using disasters, plagues, and war. Spread chaos worldwide, combine catastrophic events, and stop them before they escape to the Ark.

Afterinfection is a brand new zombie survival game designed in Unreal 4 and being developed by a small team from Thailand. After creating your survivor, you’ll start with nothing and have to make your way across a large island searching for food, water, weapons, and crafting supplies.

In a world overrun by the undead, build a lab to fight back with science. Manage survivors, gather vital resources, and turn zombies into allies. Defend your base and research the cure to reclaim humanity.

Hit the pedal, run out the offroad.

In Walking Survival, the darkness is closing in, and monstrous creatures are coming for you! Harness the power of magic, develop unique abilities, and obliterate waves of enemies before they overwhelm you.

In 'Evotinction', a third-person hacking and stealth game, you are Dr. Liu, the only one who can stop rogue AIs in a futuristic research facility. Use a variety of hacking skills to overcome robotic threats and uncover the secrets that hold the key to humanity's survival or its potential extinction.

This Is the President is a political thriller. You are the newly elected leader with a shady background. It is up to you to abuse the position of the most powerful man in the world to escape justice for past crimes – even if that pitches the country into utter chaos.

Play as the zombies! Infect and Destroy is an indie game in which you play as an infectious disease with the sole purpose of eliminating everyone on Earth. Play as an ultra-intelligent self-aware virus capable of reanimating the dead and turning them into your minions.

A world where you can create your own zombie apocalypse to your liking!

Perfect Heist is a round-based online game, where the robber team tries to execute a bank robbery without getting noticed, and the cop team tries to prevent it. Robbers hide in plain sight and try to slowly infiltrate the bank while the Cops try to figure out who is a normal customer, and who is a robber!

Examine and test patients for common and novel infections using sophisticated medical instrumentation and disinfection procedures. All infected patients must be sent to the isolation ward for further evaluation or treatment. Rumors of mysterious diseases and human experimentation are unconfirmed.

Explore infinite possibilities with INFINITE LIVES - where superhumans and subhumans fight for control of the ultimate shared universe! Bursting into the 3rd dimension brings new powers with unprecedented freedom, in a vicious cycle that never ends...

40 Days is a special strategy simulation game related to infectious diseases spread all over the city. You, as ahead of the quarantine department, have been given full authority and manpower to contain the city, deal with different parties, virus in the city and most importantly find out the cure.

A first-person shooter meets quarantine inspection in post-apocalyptic Chicago. You’ve got 30 days until the army arrives. Hold out, fix your car, and fight your way through Chicago to the main checkpoint to save your little brother.

Dive into the heart of aviation mysteries in "Plane Accident: Prologue." Explore realistic crash sites, analyze evidence, and solve puzzles. Unveil the truth in this thrilling prelude to the full "Plane Accident" experience.

WARNING. Stay inside. Lock your doors. Close the blinds. Only let humans in. Eliminate all Visitors. An anxiety horror about paranoia in the End of Times.

A Huge Wave of Zombies Are Coming! Control hundreds of swarming zombies to conquer the entire city!

COVID: The Outbreak is a real-time strategy game in which you play the role of a global organization that has to deal with a global pandemic. Issue decrees, manage resources, develop projects, and construct buildings. A race for the vaccine begins!

You will have to visit the patient's apartment, find out about the agent's disappearance and submit a report to VGL Corporation. The task is easy, but after you enter the apartment, the picture will change and only the goal will remain - to survive!

You play as a salaryman who gets caught in various everyday troubles and overcomes them with acrobatic bows. From boss reprimands to client complaints and family issues, showcase your elegant apology skills across different scenarios. What shocking ending awaits?

A story-driven survival visual novel inspired by SCP-610. Face a flesh-spreading outbreak, make brutal moral choices, protect the people you can’t let go of, and uncover the terrifying truth behind the disease.

THE SHRiNK is an AVN. You play as Alex (default name) you can choose your name, and the names of the rest of the main cast. You can also choose your relationship with them from the very start of the game. Choices in this game will decide the type of content you see or miss out on.

Virus Petya - a simulator of the system administrator. In this game you need to run from one computer to another, to remove from the computer a terrible virus "PETYA". But it's not easy, because with each attempt of the virus to infect the computer, the virus gets closer to the end of his successful work

Sweet raging fast zombie revenge!

Undead Inc. is a high-risk, high-reward resource management simulator where you establish and manage a local subsidiary of the Endswell Medical Corporation. Build, manage staff, conduct research, and trade in both cutting edge medical treatments and bleeding edge bioweapons.

A free, first-person, short medical horror experience that is an early rendition of the prequel we envisioned for Negative Atmosphere.

Erotic text-based adventure of blue alien women, parasites, and spaceships.

COVID SIMULATOR is an outbreak simulation that visualizes how quickly Covid-19 spreads, becoming a disaster. The game is an open sandbox where you can add (or remove) Covid mandates and see what happens! Create your workplace, enact your mandates, and roll the dice with your workers.

Become a parliamentarian, create a powerful party, and lead it to victory in this humorous adventure game. Manage your popularity and dignity, use unique powers, and navigate a storyline inspired by current events.

Zombies Attack is a retro pixel horizontal action game. You will face a large number of zombies and bosses in the doomsday. Pick up your weapons and fight your way out of the zombies! !

Distancing is a social distancing game where you are going to a party, but on the way you need to try and keep the social distancing.

Extremely realistic simulator with unprecedented features that let you finally vent all the anxiety modern world induces in you.

No More Room in Hell 2 is an intense 8 player zombie shooter. Overcome the endless undead. Avoid infection. Survive hell together.

The apocalypse is here, and you saw it coming. Survival Log is a zombie-apocalypse hoarding survival sim. Hoard supplies, reinforce your home, and optimize every run before zombies flood the city. Every failure becomes experience. You must adapt and survive this time.

Inspired by Max Brooks' World War Z novel, Z-Collapse takes you into a worldwide zombie apocalypse. As leader of the government of your choosing, make sure your country survives! Dramatic decisions are ahead of you. How do you manage them?