Games Like Bio Inc. Redemption

Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.

Why similar: Outbreak Sim 57.8% ★, Strategy 10.4%, Simulation 8.2%, Zombies 6.2%, Multiplayer 4.8%

Why You'll Like It: This is the definitive outbreak simulation that mirrors the core 'plague' gameplay of the seed game with deep strategic evolution mechanics.

Become an ace doctor, an aspiring architect and a successful manager at the same time. Design your very own hospital, tweak every detail or choose one of the prebuilt scenarios and just jump to the doctor’s duty.

Why similar: Medical Sim 55.9% ★, Management 13.2%, Education 11.3%, Sandbox 9.1%, Simulation 5.2%

Why You'll Like It: It provides the most detailed medical management experience, allowing you to oversee every aspect of a hospital's operations and patient care.

A unique and deeply engaging political/military strategic simulation from the creator of Plague Inc. Balance competing civilian and military priorities and deal with a deadly insurgency in order to stabilise a war-torn country.

Why similar: RTS 32.3%, Sandbox 22.5%, Multiplayer 15.8%, Strategy 13.6%, Simulation 12.3%

Why You'll Like It: Developed by the same team as Plague Inc, it offers a similar high-stakes strategic management experience focused on controlling complex, evolving scenarios.

What if you had it in your power to rid the world of disease, to improve the lives of millions, to ease suffering and cure the sick… and earn a tidy profit? As the head of your own Pharmaceutical Conglomerate you have this power resting in your hands. Will you use it for good?

Why similar: Medical Sim 60.7% ★, Management 17.1%, Sandbox 7.2%, Simulation 6.6%, Strategy 5.4%

Why You'll Like It: This game captures the scientific and ethical dilemmas of the pharmaceutical industry, requiring you to balance profit with medical advancement.

A campy, crazy pixelart zombie apocalypse arcade sim where you're the bad guy. Drop your virus and spread it across the globe while you unlock a whole horde of bizarre undead to do your bidding.

Why similar: Outbreak Sim 60.3% ★, Zombies 12.8%, Difficult 8.4%, Strategy 6.1%, Simulation 5.5%

Why You'll Like It: It offers a fast-paced, darkly humorous take on the outbreak simulation genre with a focus on global destruction.

Become a mad scientist! Conduct crazy experiments, mix mutagens, breed abominable creatures, and attach monstrous body parts to them. Manage your inventory, expand your lab, and make sure your hideout is safe. Send your creations into the city to obtain salvage and test subjects!

Why similar: Medical Sim 40.5% ★, Sandbox 12.7%, Zombies 9.9%, Management 8.7%, Horror 7%

Why You'll Like It: This game leans into the 'mad scientist' aspect of biological experimentation, requiring you to manage a lab and create horrific mutations.

Design stunning hospitals, cure peculiar illnesses and manage troublesome staff as you spread your budding healthcare organisation across Two Point County.

Why similar: Medical Sim 64.3% ★, Management 15.9%, Simulation 8.3%, Sandbox 5.9%, Strategy 2.9%

Why You'll Like It: A classic management simulation that focuses on the logistical challenges of running a hospital, albeit with a more comedic tone.

Reanimation inc is a completely realistic simulation - real urgent conditions and diseases, real protocols of care used in an ambulance, realistic simulation of the body! Do you like realistic games about medicine and simulators, games you need to think about? You 'll be happy!

Why similar: Medical Sim 73.4% ★, Gore 14.7%, Simulation 9%, Indie 2.9%

Why You'll Like It: A realistic medical simulator that focuses on the technical aspects of life-saving procedures and patient monitoring.

Manage emergency services in any city in the world! Take calls and dispatch rescue forces. Handle difficult situations, now depending on the weather, and traffic. Help the citizens through cataclysms and natural disasters, becoming a better emergency number operator every day!

Why similar: Medical Sim 41.5% ★, RTS 12.3%, Education 12.1%, Management 11.2%, Sandbox 9%

Why You'll Like It: It emphasizes high-pressure emergency management and critical decision-making, forcing you to prioritize resources during crises.

The Fabulous Fear Machine is a narrative-driven strategy game with a pulp horror style. As the Machine's new Master, you must sow fear and expand your influence by creating Legends, harvesting resources, manipulating events, and spying on your enemies.

Why similar: Outbreak Sim 54.8% ★, Difficult 11%, Management 8%, Horror 6.4%, Simulation 6.1%

Why You'll Like It: It focuses on the strategic manipulation of public opinion and the spread of influence, similar to the tactical depth of Bio Inc.

Choose any real region from the world. Choose your base of operations, then rebuild and readapt the buildings around you to create a self-sustaining settlement. Take charge of a group of survivors from your city. And when the night falls - Defend the zone from the infected!

Why similar: Outbreak Sim 31.2% ★, Post-apocalyptic 13.9%, Zombies 12.2%, RTS 11.5%, Management 10.1%

Why You'll Like It: Focuses on base-building and survival in a world devastated by a biological threat.

Evil Labs is a game about building and managing your own Evil Laboratory. Research and develop diseases, infect people, sell the cure and get rich!

Why similar: Outbreak Sim 79.2% ★, Simulation 8.7%, Strategy 8.1%, Indie 2.8%, Singleplayer 1.2%

Why You'll Like It: This game combines base-building with biological research, tasking you with managing a secret facility to unleash a virus.

Quarantine is an intense turn-based strategy game about waging war on pandemic disease. Recruit a team of specialized operatives to deploy on worldwide missions. Research the contagion, upgrade your tech, and quarantine the outbreak before it kills us all.

Why similar: Outbreak Sim 76.7% ★, Strategy 9.8%, Simulation 6.8%, Difficult 3.4%, Atmospheric 2%

Why You'll Like It: A turn-based strategy game that focuses on the tactical containment of global outbreaks.

Autopsy Simulator is a first-person horror-sim hybrid where players take on the role of a practice pathologist and study case files, created in collaboration with real-world forensic doctors, to help guide their dissection of anatomically accurate bodies to determine each subject’s cause of death.

Why similar: Medical Sim 56.2% ★, Gore 16.9%, Simulation 11.5%, Horror 6.2%, Sexual Content 2.9%

Why You'll Like It: Focuses on the morbid, anatomical side of medical simulation with a strong emphasis on realistic procedure.

Frostpunk is the first society survival game. As the ruler of the last city on Earth, it is your duty to manage both its citizens and infrastructure. What decisions will you make to ensure your society's survival? What will you do when pushed to breaking point? Who will you become in the process?

Why similar: Post-apocalyptic 33.4%, Strategy 17.5%, Management 15.1%, RTS 11.7%, Difficult 8.6%

Why You'll Like It: A high-stakes management game where every decision involves life-or-death consequences for your population.

Potion Craft is an alchemist simulator where you physically interact with your tools and ingredients to brew potions. You're in full control of the whole shop: invent new recipes, attract customers and experiment to your heart's content. Just remember: the whole town is counting on you.

Why similar: Management 38.6%, Sandbox 29.6%, Simulation 19.7%, Singleplayer 7%, Indie 5.1%

Why You'll Like It: It focuses on the scientific process of experimentation and resource management to create specific concoctions.

Surgeon Simulator is an over-the-top operation sim, stitching together pitch-black humour with life-saving surgery. Become Dr. Burke, a would-be surgeon with a less than conventional toolkit, as he performs procedures on patients including the Heavy from TF2! ...is that a hammer?

Why similar: Medical Sim 69.5% ★, Difficult 14.5%, Simulation 7.4%, Gore 4.8%, Indie 2.5%

Why You'll Like It: It highlights the visceral, physics-based gore and medical challenge aspect of the genre.

Lovecraftian Doctor Simulator. Diagnose patients by analyzing unsettling symptoms and treat them using your Book of Medicine. Make moral choices — decide who to save or kill, discover whom to trust, and unlock multiple endings! Can you endure 30 days of perilous decisions?

Why similar: Medical Sim 79.6% ★, Management 11.3%, Atmospheric 4.9%, Simulation 4.2%

Why You'll Like It: A narrative-driven medical simulator that forces players to make difficult ethical choices in a high-pressure environment.

Dedicate your life to saving others. As soon as you receive the emergency call, speed off to the site of the accident in your ambulance, sirens wailing. Apply first aid and transport the seriously injured to hospital. Every second counts!

Why similar: Medical Sim 69.3% ★, Simulation 10.7%, Gore 7.6%, Management 7.3%, Atmospheric 3.5%

Why You'll Like It: Provides a real-time, hands-on perspective of medical emergency management and triage.

A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more.

Why similar: Management 30%, Sandbox 28.1%, Strategy 13.8%, Simulation 13%, Atmospheric 7.8%

Why You'll Like It: Features a deep medical system where you must manage the health, surgery, and survival of your colonists in a complex environment.

Play a doctor in Vital Signs: Emergency Department and challenge your medical knowledge to help treat a wide array of cases who come into the ER.

Why similar: Medical Sim 73.6% ★, Education 18.2%, Simulation 6.4%, Singleplayer 1.8%

Why You'll Like It: A realistic simulator that focuses on the diagnostic and time-management challenges of an emergency room.

Only the world’s most ruthless Warden can contain the world’s most ruthless inmates. Design and develop your personalized penitentiary in Prison Architect.

Why similar: Management 28.7%, Sandbox 28.4%, Simulation 14.6%, Strategy 13.1%, Multiplayer 10.6%

Why You'll Like It: A complex management simulation that requires balancing infrastructure, resources, and the well-being of individuals in a confined space.

COVID: The Outbreak is a real-time strategy game in which you play the role of a global organization that has to deal with a global pandemic. Issue decrees, manage resources, develop projects, and construct buildings. A race for the vaccine begins!

Why similar: Outbreak Sim 55.7% ★, Education 12.5%, RTS 10%, Management 8.6%, Strategy 6.7%

Why You'll Like It: A grand strategy game that simulates the global response to a pandemic, focusing on policy and resource management.

Potion Tycoon is a management simulator with a witchy twist! Build and develop your very own magic shop. Manage resources, set up production lines, mix potions and sell them smartly to stay ahead of the competition. Welcome to the potion business!

Why similar: Medical Sim 46.4% ★, Management 20.4%, Sandbox 16.1%, Simulation 8.2%, Strategy 7.3%

Why You'll Like It: Combines the management of a business with the scientific process of developing and refining medical-adjacent products.

Manage an ER during the apocalypse, solo or with friends online: diagnose patients, design and grow your hospital, and defend against the undead while treating the living. Integrate with Twitch chat for even more fun!

Why similar: Medical Sim 38% ★, Outbreak Sim 30.8% ★, Management 8.7%, Zombies 8%, Post-apocalyptic 7.8%

Congratulations. The October labor lottery is complete. Your name was pulled. For immediate placement, report to the Ministry of Admission at Grestin Border Checkpoint. An apartment will be provided for you and your family in East Grestin. Expect a Class-8 dwelling.

Why similar: Simulation 33.2%, Difficult 17.8%, Indie 17.1%, Atmospheric 12.6%, Strategy 10.9%

Why You'll Like It: A masterclass in high-stakes, morally ambiguous decision-making under strict time and resource constraints.

A young Plague Doctor, only to learn that the Academy sent to a small village, which, like the whole country is gripped by plague

Why similar: Medical Sim 42.9% ★, Outbreak Sim 36.4% ★, Education 12.6%, Horror 4.7%, Simulation 3.4%

Why You'll Like It: A survival-focused game that emphasizes the medical and societal challenges of living through a plague.

Person of European Heritage #112: Welcome to Relocation Block B, your new home. Your designated role is 'Bouncer'. Work hard, stay out of trouble, and we might let you stay in the UK.

Why similar: Simulation 63.5%, Difficult 22.8%, Indie 7.5%, Singleplayer 6.1%

Why You'll Like It: A high-pressure management game that requires strict adherence to rules and rapid decision-making under stress.

Can you rebuild civilisation after a zombie apocalypse? From the creator of Plague Inc. comes a unique blend of strategic simulation, survival city builder and ‘mini 4X’. Build settlements, harvest resources and shape society as you lead Humanity out of the darkness.

Why similar: Outbreak Sim 50% ★, Post-apocalyptic 14%, Zombies 12.9%, Management 10.4%, Simulation 6%

Command the checkpoint in a collapsing city. Screen survivors, manage scarce resources, and hold back the undead. Every choice matters and one mistake could unleash the plague beyond your walls.

Why similar: Zombies 27.7%, Post-apocalyptic 26.7%, Management 20%, Simulation 13.1%, Atmospheric 8.7%

This is a 18+ hospital simulation game. You will play the role of the hospital director and manage a hospital.

Why similar: Medical Sim 64.5% ★, RTS 17.6%, Sexual Content 7.7%, Simulation 7.7%, Indie 2.2%

COVID SIMULATOR is an outbreak simulation that visualizes how quickly Covid-19 spreads, becoming a disaster. The game is an open sandbox where you can add (or remove) Covid mandates and see what happens! Create your workplace, enact your mandates, and roll the dice with your workers.

Why similar: Outbreak Sim 59.8% ★, Education 18.7%, Management 15.2%, Simulation 4.1%, Atmospheric 1.5%

DeadOS is an early access zombie outbreak simulator by Benn Powell that focuses on city-wide scenarios where you have access to fully customize your apocalypse experience from beginning to end. Simulation. Sandbox. Survival!

Why similar: Outbreak Sim 72.8% ★, Gore 9.2%, Zombies 5.5%, Simulation 5.1%, Sandbox 5%

《中国战疫》是一款科普防疫知识的模拟经营类游戏，玩家将临危受命地前往不同地区进行疫情控制，展示中国防疫的成功经验，最终达成疫情控制和经济稳定的双赢。

Why similar: Medical Sim 42.8% ★, Outbreak Sim 36.7% ★, RTS 10.6%, Simulation 4.4%, Strategy 3.2%

Play as the zombies! Infect and Destroy is an indie game in which you play as an infectious disease with the sole purpose of eliminating everyone on Earth. Play as an ultra-intelligent self-aware virus capable of reanimating the dead and turning them into your minions.

Why similar: Outbreak Sim 75.9% ★, Zombies 8.2%, Strategy 6.9%, Simulation 6.7%, Indie 2.4%

A short medical simulation horror game with multiple endings where the imperfect are made HAPPY. Perform tasks and operations on sedated patients to fix their defects before submitting your files to the Ministry of Happiness & Peace!

Why similar: Medical Sim 72.7% ★, Gore 7.8%, Simulation 7.4%, Horror 6.6%, Atmospheric 4%

Game about the difficult work of people that manage emergency lines and services. Answer incoming calls and react properly - give first aid instructions, advise, dispatch correct number of firemen / police / ambulances, or sometimes - just ignore the call. Play on ANY CITY in the world!

Why similar: Management 34.2%, Simulation 21.1%, Strategy 19.3%, Education 14.4%, Atmospheric 3.8%

Awaken the incompetent doctor within you! Diagnose strange patients, examine their absurd symptoms… and prescribe treatments that could change their lives… or cut them short. Your actions will have consequences.

Why similar: Medical Sim 77.8% ★, Management 12.3%, Simulation 7.6%, Singleplayer 2.3%

2D pixel style simulation business strategy game Build and operate your own survivor base, recruit and cultivate various professional combatants. Clear zombie strongholds, reduce regional infections, survive in the apocalypse, and establish your own power.

Why similar: Outbreak Sim 40% ★, RTS 16.1%, Post-apocalyptic 15.2%, Zombies 13.7%, Simulation 7.3%

Live the experience of being a powerful god and create the world to see the growth of mankind.

Why similar: Outbreak Sim 48.5% ★, God Game 13.8% ★, Sandbox 13.2%, Difficult 7.2%, Strategy 5.6%

Experience a realistic pharmacy management experience with Pharmacy Simulator. Set up your shop, decorate it as you wish, and purchase over a hundred types of medications. Pharmacy Simulator offers you an incredibly realistic pharmacy experience. Prove your skills in a challenging economic system.

Why similar: Medical Sim 66.2% ★, Simulation 12.3%, Education 11.4%, Management 8%, Indie 1.3%

You have awoken as a small god. As you accumulate the faith and souls of your followers, you will learn incredible new abilities. Protect, guide your people and smite any threats that may arise. The fate of your world is in your hands.

Why similar: Outbreak Sim 44.7% ★, God Game 13.6% ★, Management 13.4%, Sandbox 11.9%, Strategy 6.5%

Step into the shoes of a dedicated medical professional in Doctor Life Simulator. Experience the challenges and triumphs of running your own medical practice, from diagnosing complex illnesses to performing life-saving surgeries.

Why similar: Medical Sim 72.3% ★, Management 16.5%, Simulation 8.2%, Singleplayer 1.8%, Indie 1.3%

Weedcraft Inc explores the business of producing, breeding and selling weed in America, delving deep into the financial, political and cultural aspects of the country's complex relationship with this troublesome and promising plant.

Why similar: Medical Sim 42.9% ★, Management 17.8%, Simulation 17.5%, Strategy 15.7%, Indie 4.9%

Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.

Why similar: Medical Sim 39% ★, Outbreak Sim 32.6% ★, RTS 11.5%, Management 9%, Strategy 4.1%

Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time!

Why similar: Medical Sim 40% ★, Outbreak Sim 29.3% ★, Education 15.6%, Simulation 7.9%, Strategy 6.8%

Plague M.D. is a medieval medicine simulator. Become a quack doctor stuck in a backwater village in the 16th century.

Why similar: Medical Sim 51.9% ★, Simulation 15.8%, Difficult 14.4%, Atmospheric 8.3%, Indie 6%

Stop a deadly plague in a medieval fantasy tale of swords and surgery! Unearth medical knowledge, prevent the town’s purge, or plot your own escape.

Why similar: Medical Sim 82.7% ★, Horror 8.5%, Indie 6.1%, Singleplayer 2.7%

Take charge of a WW1 field hospital on the Western Front, and make all the decisions necessary to help the soldiers recover and to support the war effort. In this narrative management game, you are the last bastion of humanity.

Why similar: Medical Sim 61.9% ★, RTS 17.1%, Management 14.5%, Strategy 6.5%

In this psychological horror game, you are a doctor with only 12 days to save a town from a mysterious plague. Make ruthless decisions and diagnose with precision. Shape the town's future and rewrite the past. Hold yourself together while it all falls apart.

Why similar: Horror 31.4%, Difficult 27.6%, Atmospheric 21.2%, Simulation 19.8%

Discover the life of Dr Greenstuff, grow marijuana, coca, make meth', drugs and more to keep your legal/illegal business running.

Why similar: Medical Sim 76.5% ★, Simulation 10.5%, Sandbox 9.5%, Indie 3.5%

The most blasphemous, diabolical and insane management game ever created. Aided by a lascivious nun in a grim prison, rig executions, conduct horrid experiments and do the unspeakable to cook up your cure-all: The Kindeman Remedy. Do not be afraid. This time, you're the monster.

Why similar: Medical Sim 71.1% ★, Management 16%, Horror 6.2%, Simulation 5.1%, Singleplayer 1.6%

The post-apocalyptic dark comedy is back - remastered and even more radioactive than before! Scavenge supplies, rescue your family, and stay alive in your fallout shelter. Make difficult decisions, hunt mutant roaches... and maybe survive. Or not.

Why similar: Outbreak Sim 49.9% ★, Management 13.1%, Post-apocalyptic 13%, Difficult 12.2%, Strategy 6.3%

Play as a lethal virus infecting various organs in your host's body while trying to outsmart the immune cells that seek to eliminate you and your kind. Generate clones and watch them propagate, infecting cells and taking down bosses.

Why similar: Outbreak Sim 81.2% ★, Simulation 9.3%, Atmospheric 7%, Indie 1.9%, Singleplayer 0.6%

Rebuild a ruined city in this post-apocalyptic mix of strategy and simulation. Manage survivors, scavenge for food and supplies, deal with rival gangs, illness, interpersonal strife and zombie attacks.

Why similar: Outbreak Sim 35.2% ★, Post-apocalyptic 14.5%, Zombies 13.2%, Management 12.6%, Sandbox 12%

The Last Plague: Blight is an authentic survival experience rooted in realism and immersion. Endure the hazards of a brutal open world and uncover the origins of a mysterious disease. You are humanity’s final hope in ending the Blight

Why similar: Sandbox 44.6%, Post-apocalyptic 36.8%, Atmospheric 13.5%, Singleplayer 5.1%

Cepheus Protocol is an Open World RTS Military Survival Game. Play as the CERC hunting Patient 0, maintain Quarantine camps, fight dangerous mutations & Rogue Civilian Combatants . There’s nobody else coming, it’s up to you now.

Why similar: RTS 21.7%, Sandbox 17.1%, Gore 16.3%, Zombies 16%, Post-apocalyptic 15.8%

Create your own unique religion in god simulator strategy sandbox games

Why similar: RTS 38.1%, God Game 30.3% ★, Strategy 16.3%, Simulation 15.3%