60+ similar titles based on shared tags and player behavior. Themes include Singleplayer, Strategy, Tower Defense, Casual.
Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time!
Welcome To Your Immune System
Welcome to Your Immune System is an addictive retro arcade-style video game where you defend human cells from invading bacteria. Use all the weapons in your arsenal from macrophages, killer T cells, to cytokines and learn how these work in real life.
Defend Your Life: TD
Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy.
Welcome to Your Immune System is an addictive retro arcade-style video game where you defend human cells from invading bacteria. Use all the weapons in your arsenal from macrophages, killer T cells, to cytokines and learn how these work in real life.
Why similar: Medical Sim 37% ★, Science 30.5% ★, Education 21.7%, Action 4.9%, Colorful 3.4%
Defend Your Life! Is tower defense set in human body where players are fighting against villain hordes of viruses and bacteria. Levels and units correspond to reality of human anatomy.
Why similar: Tower Defense 46.7%, Education 25.5%, Strategy 12%, Tactical 6.9%, Colorful 4.1%
Play a doctor in Vital Signs: Emergency Department and challenge your medical knowledge to help treat a wide array of cases who come into the ER.
Why similar: Medical Sim 55.7% ★, Education 27.1%, Simulation 10.5%, Colorful 3.3%, 2D 2.7%
Play as a lethal virus infecting various organs in your host's body while trying to outsmart the immune cells that seek to eliminate you and your kind. Generate clones and watch them propagate, infecting cells and taking down bosses.
Why similar: Science 42.9% ★, Outbreak Sim 41.4% ★, Simulation 10.7%, Action 3.8%, 2D 1%
PolyCore Defense is a tower defense game where you have to raise your defenses in order to defend your core. Build unique turrets, upgrade them with special effects and use abilities to survive waves of enemies that are trying to destroy your core!
Why similar: Tower Defense 63.8%, Strategy 15.9%, Action 8%, Tactical 7.3%, Colorful 3.9%
Infinitode 2 - a strategy in the Tower Defense genre, in which the player will have to build towers to protect his base from endless waves of enemies. The game features huge maps, lots of towers, resource miners, upgrade tree and map editor.
Why similar: Tower Defense 53.2%, Strategy 13.7%, Tactical 12.7%, PvE 8.4%, Colorful 6.4%
Auto Cell run in a two-dimensional grid world. Each grid can be regarded as a small life. It has two states: survival or death.
Why similar: Science 42.9% ★, Simulation 29.6%, Strategy 23.5%, 2D 3.5%, Singleplayer 0.5%
"Last Stand:Defense" is a tower defense-themed Rogue-like game. Players need to defend against waves of enemies by building bases, matching talents, and performing delicate operations during battles. Remember, every choice you make will affect the final outcome of the battle!
Why similar: Tower Defense 71.2%, Strategy 20.2%, Tactical 7.5%, Singleplayer 1.2%
A tower defense action roguelike where you control a single tower to fight against hordes of aliens coming from all directions. Pick your tower, equip up to 4 skills, and choose from a variety of traits and items to craft powerful builds that lead you to victory.
Why similar: Tower Defense 65.7%, Strategy 17.7%, Action 10.1%, 2D 5.7%, Singleplayer 0.9%
In a world overrun by the undead, build a lab to fight back with science. Manage survivors, gather vital resources, and turn zombies into allies. Defend your base and research the cure to reclaim humanity.
Why similar: Science 40.5% ★, Tower Defense 30.2%, Base Building 10.5%, Simulation 9.9%, Strategy 8.2%
Cyber Tower 2048 is an action tower defense game where players fight insectoids by building defenses and developing tactics.
Why similar: Tower Defense 67.8%, Action 13.3%, Colorful 8.1%, Strategy 6.4%, 2D 3.5%
Build your biome! With an empty biodome as your canvas, add plants and animals from three different ecosystems. Observe interactions like hunting, blooming, and even decomposing! Will your biodome last for decades, or will it experience a total ecosystem collapse? You’re in control!
Why similar: Science 44.2% ★, Education 24.2%, Simulation 21.3%, Strategy 10.4%
Trial of Empires TD, is a Free to Play 3D tower defense game. Pick your ally and build your strategy with different combinations. Compete with other players on the Leaderboards with Single-Player or CO-OP game modes
Why similar: Tower Defense 57.8%, Strategy 14.7%, Action 12.3%, Tactical 9.5%, Colorful 4.9%
Play as an Octopus scientist fighting off sunken skeletons in this frantic aquatic Tower Defense! Discover sea life turrets from unique biomes: Pistol Shrimp! Navy Seal! Death Ray! Deploy turrets whilst dodging enemy bullets as you venture the seven seas!
Why similar: Tower Defense 56.5%, Strategy 14.4%, Base Building 9.5%, Tactical 7.5%, Action 5.8%
In a near future, the world has been devastated by a virus turning humanity into zombies. You are Iron Corps, the last defense of civilization traveling the world to find resources, help people and find answers. Will you survive long enough?
Why similar: Tower Defense 46.1%, Strategy 19.9%, Simulation 17.5%, Action 8.4%, Tactical 8.1%
Zero Zone 2020 is a classic Tower defense game where you will need to defend a home base from swarms of enemies
Why similar: Tower Defense 69.7%, Strategy 18.9%, Action 11.4%
Firebase Defence is a new spin on the traditional tower defence gameplay. You have to defend yourself from the waves upon waves of incoming enemies. You are free to build, place and manage your available resources and units in any way you want. But failing to balance those will result in defeat!
Why similar: Tower Defense 50.3%, Strategy 18.2%, Base Building 11.5%, Action 11.3%, Tactical 5.9%
DEFENSURVIVOR is a strategy game where you build obstacles and place and move units to block zombies. There are various units with unique characteristics and powerful high-level units that can be obtained through combination. Use randomly given units to survive until the end!
Why similar: Tower Defense 47%, Base Building 13.6%, Simulation 11%, Strategy 10.8%, PvE 7.6%
COVID SIMULATOR is an outbreak simulation that visualizes how quickly Covid-19 spreads, becoming a disaster. The game is an open sandbox where you can add (or remove) Covid mandates and see what happens! Create your workplace, enact your mandates, and roll the dice with your workers.
Why similar: Science 35.3% ★, Outbreak Sim 34.9% ★, Education 22%, Simulation 5.4%, 2D 2.3%
Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its functions to a fully fledged system! Assemble, breathe, eat, fight threats, produce energy, grow, anything is possible!
Why similar: Science 59.4% ★, Base Building 13.2%, Strategy 11.4%, Simulation 9.7%, 2D 3.2%
Farm Defense pits you against waves of increasingly difficult enemies in a Tower Defense environment. Mitigate the random elements to defend the farm. Conquer all 40 waves to live and fight another day.
Why similar: Tower Defense 76.8%, Strategy 22.4%, Singleplayer 0.8%
Defense Clicker is an clicker game which will be soon F2P, with an tower defense theme and a few twists which make it very unique. You have to build an defense line with towers and upgrade them to stay alive as long as possible. when you die the map resets but you get a few special points depending on how long you survived.
Why similar: Tower Defense 72.8%, Strategy 27.2%
Crypto: Against all odds is a tower defense game, where you take the role of a cybersecurity expert to fight against hackers and other blockchain threats in this cypherpunk interactive fiction. Combined with squad customization, base/tower building, and simulation. Defend the blockchain!
Why similar: Tower Defense 56.4%, Base Building 14.5%, Strategy 14.2%, Tactical 13.8%, Singleplayer 1.1%
M.A.C.E. Tower Defense is a classic tower defense game with unique towers and enemies and an ingame shop system for getting better towers, upgrade existing towers and buy special items.
Why similar: Tower Defense 57.2%, Strategy 27%, Action 15.8%
Get ready for the ULTIMATE tower defense onslaught. Build, deploy, research and upgrade your defenses in this epic, old school RTS inspired sci-fi adventure.
Why similar: Tower Defense 54.3%, Strategy 14.1%, Tactical 12.4%, Action 7.7%, PvE 6.6%
Last Outpost is a minimalist Base Building & Strategy game where you build and defend your outpost in zombie apocalypse. Choose your vehicle and loadout before embarking on your adventure. Use your abilities and control your units to eliminate all threats. Will you manage to defend your outpost?
Why similar: Tower Defense 59.5%, Base Building 15.5%, Strategy 15.1%, Tactical 9.2%, Singleplayer 0.6%
Zombie Tower Defense: Join the ongoing war, in an open world, against the undead zombie horde. Choose between multiple powerful heroes all with unique epic gear and skills! With the wide variety of towers you can create your own perfect strategy.
Why similar: Tower Defense 85.4%, Strategy 14.6%
Take control of the hive and protect it from enemies. Build factories and defence, research technologies and, if necessary, use nuclear weapons, but do not let the enemies harm the queen!
Why similar: Tower Defense 48.6%, Tactical 12.2%, Base Building 11.5%, Strategy 11.1%, Physics 8.1%
Build and protect your home after a nuclear apocalypse!
Why similar: Strategy 48.8%, Tower Defense 39.2%, Simulation 11.2%, Singleplayer 0.7%
"Age of Steel: Recharge" is a 2D strategy with a view from the side. You're taking the role of commander, who was entrusted the management of the military base. Your mission is to defend a base from the waves of enemies at any price.
Why similar: Tower Defense 44.2%, Strategy 38.4%, Action 17.4%
Employ lethal turrets, traps, and gadgets to defend against an onslaught of evolving creeps! Step into a twisted, hyper 3D, mind bending realm. Upgrade and adapt your defenses. Become a master maze crafter. Collect bizarre artifacts. Rush creeps for lucrative rewards, and succumb to greed!
Why similar: Tower Defense 64%, Strategy 15.3%, Tactical 8.7%, Action 6.2%, Colorful 4.7%
Idle Tower Defense is a game where you control a single tower to fight off hordes of enemies. No randomization. Choose from a variety of modules to create unique builds and upgrade modules and survive endless waves.
Why similar: Tower Defense 76.9%, Strategy 11.8%, Colorful 8.5%, 2D 2.4%, Singleplayer 0.4%
Defend against thousands of enemies in this explosive tower defense game. Deploy upgradable towers and unleash powerful orbital abilities as you try to protect Earth's first colony world from destruction.
Why similar: Tower Defense 47.5%, Base Building 12.4%, Strategy 11.8%, Tactical 9.6%, PvE 7.5%
Colony Siege combines the best of RTS and tower defense, including base building, mazing, and unit physics. Defend Earth's remaining colonies using an arsenal of deadly weapons to torch, slice, throw, and impale swarms of alien invaders.
Why similar: Tower Defense 42%, Strategy 29.5%, Simulation 23.3%, Base Building 5.2%
Rush for Glory is featuring challenging and rewarding Tower Defense battles, in which players are defending their base against an alien invasion. By strategically building towers and upgrading them, the player can keep his base safely and further progress through the extensive singleplayer campaign.
Why similar: Tower Defense 70.1%, Strategy 20.3%, Action 9.6%
Defense Task Force Featuring Large Scale Procedurally Generated Tower Defense Battles with FPS Quality Visuals and Infinite Waves. 10 tower types, with different attacks , 3 levels plus boosts. 25 Enemy alien species: Regulars, Swarmers, Racers, Cloakers, Healers, Boss Units and Spawners.
Why similar: Tower Defense 62.1%, Simulation 19.3%, Strategy 18.6%
A minimalist rogue-like tower defense where you protect Earth against humanity.
Why similar: Tower Defense 77.7%, Action 11%, Colorful 10.2%, Singleplayer 1.1%
InCell is an action/racing VR game with a bit of strategy and science thrown into the mix. You'll take an exciting journey inside the highly unusual micro world of human cell and stop the virus advance. The game is focused on VR but you can play just fine without a set.
Why similar: Science 47.9% ★, Education 18.8%, Strategy 16.3%, Simulation 8.2%, Physics 4.8%
Mechs V Kaijus is an addictive hardcore tower defense gameplay. In Mechs V Kaijus you take on the role of Commander of a powerful Mechs squadron. Improve your Mech, strategically place towers and factories on the battlefield. Deploy support units on the battlefield, and save our civilization.
Why similar: Tower Defense 79.3%, Strategy 9.4%, Action 4.2%, Tactical 3.4%, Base Building 3.4%
In Your Face TD is a Tower Defense, which utilises room scale VR to give a new dimension to a classic genre. Fight the invading monsters face-to-face using a laser minigun, or even an exploding sawblade frisbee and build towers to stand your ground.
Why similar: Tower Defense 56.8%, Strategy 27%, Action 16.3%
"Infectonator : Survivors" is a Randomized Permadeath Survival Simulator that combines RTS, Tower Defense, Roguelike, and Management-Simulation gameplay. The goal is to lead a group of survivors in a struggle to stay alive and find rescue in a zombie apocalyptic world.
Why similar: Tower Defense 51.1%, Strategy 23.1%, Simulation 16.5%, Action 7.5%, 2D 1.3%
Multicellular will take you back in time, to the dawn of life. Build your multicellular organism and combat hunger, the environment, darkness and other organisms. Everything in this new world can kill you, will you be able to survive?
Why similar: Science 62.7% ★, Simulation 19.9%, Physics 11.5%, Colorful 5.9%
An exciting tower defense game where you have to defend your island from the invasion of enemy forces. Your task is to build and upgrade towers to repel waves of attacking enemies.
Why similar: Tower Defense 90%, Action 9.1%, Singleplayer 0.9%
Barricadez is a mix of tower defense and survival game. Take on your care robot and explore the underground, find new blueprints, gather resources and build your defenses and traps to survive through the night against a myriad of zombie-like creatures. Your goal: to defend the defenseless cradle.
Why similar: Tower Defense 50.4%, Base Building 14.3%, Strategy 14.1%, Tactical 10.4%, Physics 6.5%
Protolife is an unique tower-based strategy game which gives you a direct control over the builder robot in a struggle against the hungry proto-life organism.
Why similar: Tower Defense 64.7%, Base Building 18.2%, Strategy 16.3%, Singleplayer 0.8%
Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.
Why similar: Tower Defense 78%, Strategy 12.8%, Simulation 4.5%, Base Building 3.6%, 2D 0.6%
The Territory of Egg is a unique twist on tower defense game. You need to build defense lines with egg warriors to protect the Holy Egg, the core of all eggs. Remember to upgrade your Tech Tree with the resources you've collected and unlock more skills to fight against the evil monsters.
Why similar: Tower Defense 78.5%, Strategy 20.4%, Singleplayer 1.1%
Crystal Guardians prologue (small slice of the full game) is a tower defense game with rogue-like elements. Fight off waves and defend the base crystal. Gear up your towers with a powerful combination of items for your personal strategy. In a procedural map, find hidden powers and conquer the enemy.
Why similar: Tower Defense 63.7%, Strategy 16%, Base Building 14.5%, Colorful 5.5%, Singleplayer 0.2%
Survivor Challenge TD - is a Tower Defense game where you manage a single tower and add upgrades to it. Buy abilities, enhance upgrades, and defeat the boss!
Why similar: Tower Defense 59.4%, Strategy 12.1%, Tactical 11.8%, Colorful 5.9%, PvE 5.1%
Tower defense Game to safeguard the land of Rome.
Why similar: Tower Defense 63.1%, Strategy 18.5%, Simulation 7%, PvE 6.3%, 2D 4.5%
这是一款休闲益智类游戏。根据经典的PVZ类游戏的核心玩法的基础上，创新题材，创新无尽模式。
Why similar: Tower Defense 35.7%, Outbreak Sim 34.9% ★, Simulation 12.5%, Strategy 10.7%, Colorful 3.5%
Cluckmech Oasis, a top-down shooting Roguelike tower defense game. Play as the Warcluck and lead your team of animal heroes in a fight for survival. Collect, build and upgrade defenses, and engage in intense battle against waves of plant enemies.
Why similar: Tower Defense 66.8%, Strategy 18.7%, Action 8.9%, Colorful 5.4%, Singleplayer 0.3%
Defense Technica is the next evolution in hardcore tower defense strategy games. Protect the core from an onslaught of unrelenting biomechanical terrors with a powerful range of tower defense units – each with their own upgradable features and methods of attacks.
Why similar: Tower Defense 86.2%, Strategy 13.8%
Explore a war-torn city, avoid capture by soldiers, and collect the supplies Albert and Camille need to create the first vaccine to fight tuberculosis. As you progress, you will learn about the methods used to create BCG and how vaccines work.
Why similar: Education 50.9%, Science 43.2% ★, 2D 5.4%, Singleplayer 0.6%
The original, uncompleted version of Vectorio. Claim resources, unlock new buildings, and expand your defenses as you fight back against enemy forces in the classic edition of Vectorio! Play for free now.
Why similar: Tower Defense 52.9%, Base Building 16.6%, Strategy 13.6%, PvE 7.8%, Colorful 4.4%
Get ready to rethink all your defense strategies! Build barricades to stop monsters, or lure them into a maze and attack. A variety of stages that change each time depending on how you play them.
Why similar: Tower Defense 49.2%, Strategy 13.4%, Base Building 12.2%, Simulation 8.5%, PvE 6.7%
Until We Die is a side-scrolling strategy game about defending your base where you have to run around as Ivan, assign tasks to people, and fight mutants in the post-apocalyptic subway!
Why similar: Tower Defense 48%, Base Building 16.6%, Strategy 16.5%, Action 7.5%, Simulation 7.3%
You are an archer tasked with defending a castle from invading monsters. Inside the castle, you can manage resources and harvest crops, gather experience points to level up, and learn new skills and abilities to face stronger enemies.
Why similar: Tower Defense 68.8%, Strategy 16.8%, Action 9.9%, 2D 3.6%, Singleplayer 0.8%
DPSWTF is a base defense game with roguelike elements, where instead of placing towers, you build the best tower of them all. Combine the best projectiles with effective modifiers and push back the incoming hordes. Research them all to conquer the secrets of the Great North!
Why similar: Science 42.6% ★, Tower Defense 37.7%, Simulation 8.6%, Strategy 8.2%, 2D 2.8%
