Games Like Plague Inc: Evolved

Bio Inc.: Redemption is a realistic simulation and strategy game in which you make life or death decisions. Create a deadly illness to infect and torment your victim or play as the head of a medical team and hopefully find a cure to save your human patient. Will you be the plague or preserve humanity?

Why similar: Outbreak Sim 58.1% ★, Strategy 10.1%, Simulation 7.9%, Zombies 6.3%, Multiplayer 4.9%

Why You'll Like It: This medical strategy simulation closely mirrors Plague Inc.'s cause-and-effect design, letting you either sabotage a patient's health or race to diagnose and cure them.

Can you rebuild civilization after a zombie apocalypse? From the creator of Plague Inc. comes a unique blend of strategic simulation, survival city builder and ‘mini 4X’. Build post-apocalyptic settlements, harvest resources and shape society as you lead humanity out of the darkness.

Why similar: Outbreak Sim 61.8% ★, Zombies 11.2%, Strategy 9.8%, Simulation 8.4%, Post-apocalyptic 6.1%

Why You'll Like It: This direct thematic follow-up from Ndemic Games shifts the focus to rebuilding civilization after a zombie pandemic while retaining difficult strategic tradeoffs.

A unique and deeply engaging political/military strategic simulation from the creator of Plague Inc. Balance competing civilian and military priorities and deal with a deadly insurgency in order to stabilise a war-torn country.

Why similar: Strategy 29.7%, Simulation 22.3%, Tactical 16.5%, Multiplayer 14.9%, Co-op 6.7%

Why You'll Like It: From Plague Inc.'s developer, it applies the same accessible global-map strategy and adaptive decision-making to stabilizing a region after conflict.

Choose any real region from the world. Choose your base of operations, then rebuild and readapt the buildings around you to create a self-sustaining settlement. Take charge of a group of survivors from your city. And when the night falls - Defend the zone from the infected!

Why similar: Outbreak Sim 49.6% ★, Zombies 15.2%, Strategy 13.6%, Post-apocalyptic 8%, Simulation 7.8%

Why You'll Like It: This post-pandemic city-building survival game makes you establish and defend a settlement against infected hordes while scavenging a real-world map.

Quarantine is an intense turn-based strategy game about waging war on pandemic disease. Recruit a team of specialized operatives to deploy on worldwide missions. Research the contagion, upgrade your tech, and quarantine the outbreak before it kills us all.

Why similar: Outbreak Sim 72.1% ★, Strategy 13.5%, Simulation 7.3%, Tactical 3.8%, Survival 1.3%

Why You'll Like It: This turn-based global crisis game puts you on the defensive side of an outbreak, balancing containment, research, public order, and limited resources.

A campy, crazy pixelart zombie apocalypse arcade sim where you're the bad guy. Drop your virus and spread it across the globe while you unlock a whole horde of bizarre undead to do your bidding.

Why similar: Outbreak Sim 65.2% ★, Zombies 9.7%, Strategy 9.2%, Simulation 6.7%, Tactical 2.2%

Why You'll Like It: It offers the same satisfying escalation from a small infection to global collapse, but in a lighter pixel-art zombie strategy format.

COVID: The Outbreak is a real-time strategy game in which you play the role of a global organization that has to deal with a global pandemic. Issue decrees, manage resources, develop projects, and construct buildings. A race for the vaccine begins!

Why similar: Outbreak Sim 76.6% ★, Strategy 13.3%, Simulation 5.6%, Indie 2.6%, Difficult 0.8%

Why You'll Like It: It is a worldwide pandemic-management simulation centered on policymaking, medical capacity, research, and the social consequences of containment measures.

Evil Labs is a game about building and managing your own Evil Laboratory. Research and develop diseases, infect people, sell the cure and get rich!

Why similar: Outbreak Sim 76.2% ★, Strategy 11.2%, Simulation 9.5%, Indie 2.3%, Singleplayer 0.7%

Why You'll Like It: You manage an underground laboratory and develop destructive biological threats, making it a close fit for the unethical pathogen-engineering fantasy of Plague Inc.

"Pathogen" is a STG game base on real human body with little Rogue-Like element. You can propagate evolve infect and hide as different kinds of pathogens in human body.

Why similar: Outbreak Sim 81.9% ★, Simulation 14.3%, Indie 3.7%

Why You'll Like It: A fast-paced digital board game about spreading diseases across a world map, with competing pathogens and tactical control of transmission routes.

DeadOS is an early access zombie outbreak simulator by Benn Powell that focuses on city-wide scenarios where you have access to fully customize your apocalypse experience from beginning to end. Simulation. Sandbox. Survival!

Why similar: Outbreak Sim 84.5% ★, Simulation 6.9%, Zombies 4.6%, Indie 1.8%, Sandbox 1.1%

Why You'll Like It: This outbreak strategy game has you direct the spread of a zombie infection across cities while managing different undead units and resistance.

War of the Zombie brings together the best of turn-based simulation and real-time strategic gameplay action across the entire world at the very start of a mysterious undead outbreak.

Why similar: Outbreak Sim 65.8% ★, Strategy 15.6%, Simulation 11.7%, Zombies 6.9%

Why You'll Like It: It combines a global strategic map, outbreak response, research, and tactical missions in a detailed military campaign against a zombie pandemic.

Play as the zombies! Infect and Destroy is an indie game in which you play as an infectious disease with the sole purpose of eliminating everyone on Earth. Play as an ultra-intelligent self-aware virus capable of reanimating the dead and turning them into your minions.

Why similar: Outbreak Sim 73.5% ★, Strategy 9.6%, Simulation 7.4%, Zombies 5.5%, Indie 2%

Why You'll Like It: A compact infection simulator focused on unleashing diseases and watching their effects spread through populations.

In Pandemic Train you are in charge of the crew aboard a train roaming the postapocalyptic wasteland, ravaged by both war and a deadly plague. Your goal is to survive long enough to discover the cure… or die trying. Humanity’s fate is in your hands! Start your journey now!

Why similar: Strategy 34.7%, Simulation 23.6%, Post-apocalyptic 13.6%, Sandbox 7.1%, Survival 6.9%

Why You'll Like It: Rather than causing the outbreak, you lead a train full of survivors through a plague-ravaged world, making hard calls about supplies, research, and survival.

Play as a lethal virus infecting various organs in your host's body while trying to outsmart the immune cells that seek to eliminate you and your kind. Generate clones and watch them propagate, infecting cells and taking down bosses.

Why similar: Outbreak Sim 79.6% ★, Simulation 10.4%, Realistic 3.1%, Survival 1.8%, Indie 1.6%

Why You'll Like It: Its infection-centered premise and scientific simulation elements make it a fitting smaller-scale alternative for players who enjoy pathogen themes.

Prepare yourself for the most thrilling night of your life! Something strange has happened and people everywhere are turning into blood thirsty walking corpses. But guess who’s the brains behind this hungry undead army? YOU! So spread this pandemic and wipe humanity off the planet.

Why similar: Zombies 48.1%, Strategy 40.3%, Indie 6.3%, Singleplayer 1.9%, 2D 1.6%

Why You'll Like It: It lets you command and mutate a growing zombie horde to overwhelm humanity, providing a more tactical side-scrolling take on engineered apocalypse.

In a world overrun by the undead, build a lab to fight back with science. Manage survivors, gather vital resources, and turn zombies into allies. Defend your base and research the cure to reclaim humanity.

Why similar: Outbreak Sim 59.3% ★, Zombies 11.2%, Strategy 10.4%, Simulation 7.8%, Post-apocalyptic 5.7%

Why You'll Like It: This colony-management game reverses the Plague Inc. fantasy by researching a cure, capturing zombies, and rebuilding society through limited resources.

Rebuild a ruined city in this post-apocalyptic mix of strategy and simulation. Manage survivors, scavenge for food and supplies, deal with rival gangs, illness, interpersonal strife and zombie attacks.

Why similar: Outbreak Sim 50.3% ★, Strategy 14.1%, Zombies 13.2%, Simulation 9%, Post-apocalyptic 7%

Why You'll Like It: A highly replayable strategic city survival game about reclaiming a zombie-infested region through scouting, diplomacy, resource allocation, and expansion.

Frostpunk is the first society survival game. As the ruler of the last city on Earth, it is your duty to manage both its citizens and infrastructure. What decisions will you make to ensure your society's survival? What will you do when pushed to breaking point? Who will you become in the process?

Why similar: Strategy 47.5%, Post-apocalyptic 21%, Simulation 14.1%, Survival 9.6%, Difficult 3.6%

Why You'll Like It: Although driven by climate catastrophe rather than disease, its bleak survival governance, crisis management, and morally difficult policies strongly suit Plague Inc. players.

The epic story of evolution, technology, humanity, and dinosaurs is yours to tap.

Why similar: Simulation 66.9%, Casual 9.5%, Multiplayer 7.2%, Strategy 5.8%, Singleplayer 5%

Why You'll Like It: A science-focused evolution simulator that scratches the progression and organism-development side of Plague Inc. in a far more relaxed format.

They Are Billions is a Steampunk strategy game set on a post-apocalyptic planet. Build and defend colonies to survive against the billions of the infected that seek to annihilate the few remaining living humans. Can humanity survive after the zombie apocalypse?

Why similar: Strategy 38.7%, Zombies 35.3%, Post-apocalyptic 7.2%, Survival 6.5%, Tactical 5.3%

Why You'll Like It: Its relentless infected hordes and settlement-defense systems capture the pressure of trying to preserve humanity after a runaway outbreak.

Contagion isn't your average Zombie Shooter but instead takes a more realistic and different approach to the popular genre with unique characters, environments, weapons, items, and a built in system that makes every round completely unpredictable with resources, objectives, and paths ever changing.

Why similar: Zombies 58.5%, Post-apocalyptic 20.5%, Co-op 10.8%, Survival 6.6%, Atmospheric 3.5%

Why You'll Like It: A co-op zombie outbreak game where infection can turn players against the group, emphasizing the panic and collapse that Plague Inc. simulates globally.

WorldBox is the ULTIMATE god simulator and sandbox game. A petri dish for your fantasy civilizations. Create your own world or destroy it using many powers. Watch civilizations grow, form kingdoms, colonize new lands, sail to far continents, wars to ignite, empires to fall and towns to burn!

Why similar: Simulation 62%, Sandbox 26.2%, Indie 9.1%, Atmospheric 2.7%

Why You'll Like It: This sandbox lets you shape civilizations and unleash disasters, plagues, and creatures from a similarly omnipotent strategic viewpoint.

Create & destroy on an unimaginable scale with a realistic physics-based space simulator. Explore the beauty of our universe and the fragility of our planet. Use science to bend the laws of gravity, collide planets, boil away oceans, fire epic space lasers, and customize your universe.

Why similar: Simulation 41.8%, Realistic 14.6%, Sandbox 13.6%, Indie 10.1%, Casual 7.6%

Why You'll Like It: Its realistic planetary sandbox provides the same fascination with observing cascading global consequences, albeit through physics and cosmic disasters rather than disease.

Project Zomboid is the ultimate in zombie survival. Alone or in MP: you loot, build, craft, fight, farm and fish in a struggle to survive. A hardcore RPG skillset, a vast map, massively customisable sandbox and a cute tutorial raccoon await the unwary. So how will you die? All it takes is a bite..

Why similar: Zombies 36.2%, Multiplayer 15.7%, Simulation 10.6%, Post-apocalyptic 10%, Survival 8.3%

Why You'll Like It: A deep sandbox survival simulation set during a zombie pandemic, with detailed infection mechanics and an uncompromising societal-collapse atmosphere.

Endzone is a post-apocalyptic survival city builder, where you start a new civilization with a group of people after an ecological disaster. Build them a new home and ensure their survival in a shattered world, threatened by constant radiation, toxic rain, sandstorms and droughts.

Why similar: Strategy 37.3%, Simulation 20.8%, Post-apocalyptic 18.5%, Survival 6.9%, Indie 3.9%

Why You'll Like It: This post-apocalyptic colony sim focuses on guiding a vulnerable population through contamination, scarcity, disasters, and long-term rebuilding.

Command the checkpoint in a collapsing city. Screen survivors, manage scarce resources, and hold back the undead. Every choice matters and one mistake could unleash the plague beyond your walls.

Why similar: Zombies 37.3%, Simulation 29.4%, Post-apocalyptic 17.4%, Realistic 8.1%, Singleplayer 4.6%

Jump straight into managing your own planets as you guide a civilization through the ages. Build the ultimate empire in The Universim, a new breed of God Game in development by Crytivo.

Why similar: Strategy 41.4%, Simulation 31.4%, Sandbox 14.3%, Survival 9.2%, Singleplayer 3.8%

Why You'll Like It: A god-game civilization simulator where you guide a species through disasters, technological development, population pressures, and planetary survival.

ICBM is a real-time strategy game of nuclear destruction. Research new technologies, build up your nuclear stockpile and use a combination of ships, planes and missiles to strike at the heart of your opponents’ cities while keeping your population safe from harm.

Why similar: Outbreak Sim 75.1% ★, Strategy 15%, Tactical 7.8%, Multiplayer 2.2%

Why You'll Like It: A streamlined grand-strategy game about global nuclear escalation, where planning routes, timing attacks, and outmaneuvering defenses can end the world.

Return to the roots of co-op survival horror as you face monstrous hordes, scrounge for supplies and attempt to survive the nightmare. You have one life. Make it count!

Why similar: Zombies 45.7%, Multiplayer 26.7%, Indie 9.2%, Survival 7.7%, Singleplayer 5.6%

Why You'll Like It: This survival-horror game delivers the immediate human-scale consequences of a biohazard outbreak through scarce resources, infection, and branching scenarios.

End humanity using disasters, plagues, and war. Spread chaos worldwide, combine catastrophic events, and stop them before they escape to the Ark.

Why similar: Outbreak Sim 78.8% ★, Simulation 10%, Post-apocalyptic 4.8%, Sandbox 3%, Indie 1.2%

Inspired by the 1983 cult classic film, Wargames, DEFCON superbly evokes the tension, paranoia and suspicion of the Cold War era, playing on the fascinating aspects of psychological gameplay that occur during strategic nuclear warfare.

Why similar: Strategy 31%, Tactical 26.5%, Multiplayer 16.6%, Co-op 10%, Difficult 8.9%

Why You'll Like It: Its minimalist global map, escalating tension, and civilization-ending strategic warfare evoke Plague Inc.'s detached but unsettling world-scale perspective.

Be the architect of your own universe with Spore, an exciting single-player adventure. From Single Cell to Galactic God, evolve your creature in a universe of your own creations.

Why similar: Simulation 65.8%, Sandbox 22.2%, Casual 12%

Why You'll Like It: Its creature editor and evolution-driven progression offer a playful counterpart to designing and adapting an organism across changing environments.

Place yourself at the heart of the Jurassic franchise and build your own Jurassic World. Bioengineer dinosaurs that think, feel and react intelligently to the world around them and face threats posed by espionage, breakouts and devastating tropical storms in an uncertain world where life always finds a way.

Why similar: Strategy 40.8%, Simulation 37.9%, Sandbox 8.9%, Multiplayer 4.7%, Singleplayer 4%

Examine and test patients for common and novel infections using sophisticated medical instrumentation. Isolate and treat infected patients. Discover the wonders, mysteries, and horrors of medical science. Rumors of mysterious diseases and human experimentation are unconfirmed.

Why similar: Outbreak Sim 82.2% ★, Simulation 15%, Singleplayer 2.1%, 2D 0.7%

WARNING. Stay inside. Lock your doors. Close the blinds. Only let humans in. Eliminate all Visitors. An anxiety horror about paranoia in the End of Times.

Why similar: Outbreak Sim 74.8% ★, Simulation 11.1%, Indie 5.6%, Singleplayer 3.5%, Atmospheric 2.9%

The post-apocalyptic dark comedy is back - remastered and even more radioactive than before! Scavenge supplies, rescue your family, and stay alive in your fallout shelter. Make difficult decisions, hunt mutant roaches... and maybe survive. Or not.

Why similar: Outbreak Sim 72.5% ★, Strategy 13.5%, Post-apocalyptic 6.5%, Difficult 4%, Survival 2.3%

Only the world’s most ruthless Warden can contain the world’s most ruthless inmates. Design and develop your personalized penitentiary in Prison Architect.

Why similar: Strategy 35.9%, Simulation 31.6%, Multiplayer 13%, Sandbox 9.4%, Indie 3.7%

Game about the difficult work of people that manage emergency lines and services. Answer incoming calls and react properly - give first aid instructions, advise, dispatch correct number of firemen / police / ambulances, or sometimes - just ignore the call. Play on ANY CITY in the world!

Why similar: Strategy 35.5%, Simulation 30.5%, Addictive 10.5% ★, Tactical 6.1%, Realistic 4.8%

In This War Of Mine you do not play as an elite soldier, rather a group of civilians trying to survive in a besieged city; struggling with lack of food, medicine and constant danger from snipers and hostile scavengers. The game provides an experience of war seen from an entirely new angle.

Why similar: Strategy 34%, Simulation 22.1%, Survival 14.2%, Post-apocalyptic 11.5%, Realistic 5.6%

You are a disease. Infect the human body as a lone pathogen in this cellular roguelike shooter. Collect organelles to evolve your parasite in a microscopic arms race against your host's immune system. Conquer a beautiful, procedurally generated world of tiny proportions.

Why similar: Difficult 34.5%, Co-op 27.2%, Survival 16.5%, Casual 13.3%, 2D 8.5%

Jurassic World Evolution 2 is the much-anticipated sequel to Frontier’s highly successful Jurassic World Evolution. This bold new era in the Jurassic World Evolution game franchise builds upon the ground-breaking and immersive 2018 management simulation.

Why similar: Simulation 35.9%, Strategy 35.8%, Sandbox 11.2%, Multiplayer 8.6%, Singleplayer 4.6%

Victory is at your fingertips! Your ability to lead your nation is your supreme weapon, the strategy game Hearts of Iron IV lets you take command of any nation in World War II; the most engaging conflict in world history.

Why similar: Strategy 52%, Simulation 15.2%, Multiplayer 12.7%, Tactical 11.6%, Sandbox 3.4%

COVID SIMULATOR is an outbreak simulation that visualizes how quickly Covid-19 spreads, becoming a disaster. The game is an open sandbox where you can add (or remove) Covid mandates and see what happens! Create your workplace, enact your mandates, and roll the dice with your workers.

Why similar: Outbreak Sim 89.3% ★, Simulation 7%, Casual 1.5%, 2D 1.1%, Atmospheric 0.4%

Zombies are invading your home, and the only defense is your arsenal of plants! Armed with an alien nursery-worth of zombie-zapping plants like peashooters and cherry bombs, you'll need to think fast and plant faster to stop dozens of types of zombies dead in their tracks.

Why similar: Zombies 37.6%, Strategy 30.5%, Addictive 13.7% ★, Tactical 4.7%, Casual 3.4%

The Fabulous Fear Machine is a narrative-driven strategy game with a pulp horror style. As the Machine's new Master, you must sow fear and expand your influence by creating Legends, harvesting resources, manipulating events, and spying on your enemies.

Why similar: Outbreak Sim 71% ★, Strategy 11.3%, Simulation 9%, Difficult 3.2%, Indie 2.5%

2D pixel style simulation business strategy game Build and operate your own survivor base, recruit and cultivate various professional combatants. Clear zombie strongholds, reduce regional infections, survive in the apocalypse, and establish your own power.

Why similar: Outbreak Sim 53% ★, Zombies 12.6%, Strategy 11.6%, Simulation 11%, Post-apocalyptic 6.8%

In Game Dev Tycoon you replay the history of the gaming industry by starting your own video game development company in the 80s. Create best selling games. Research new technologies and invent new game types. Become the leader of the market and gain worldwide fans.

Why similar: Simulation 42.8%, Strategy 27.1%, Addictive 12.5% ★, Indie 6.8%, Casual 3.7%

Manipulate climate, add plants and evolve creatures in this planet and life sandbox simulation game. From cells to civilizations, spread life throughout the whole planet. Or just enjoy watching your creation burn!

Why similar: Strategy 46.7%, Simulation 37%, Sandbox 12.4%, Atmospheric 3.9%

Swarm the City: Zombie Evolved is a villain protagonist real-time strategy game. You will play as the King of the Dead and rule the world once again by creating zombie legions and destroying human cities. As the King of the Dead, you can infect humans, turn them into zombies and rule the world!

Why similar: Zombies 23.7%, Strategy 21.2%, Simulation 14.7%, Tactical 12.3%, Post-apocalyptic 11.6%

Rule your land and dominate the world with unparalleled freedom, depth and historical accuracy. Write a new history of the world and build an empire for the ages.

Why similar: Strategy 42.3%, Simulation 31%, Multiplayer 10.4%, Sandbox 8.4%, Co-op 5.6%

A Huge Wave of Zombies Are Coming! Control hundreds of swarming zombies to conquer the entire city!

Why similar: Outbreak Sim 66.7% ★, Simulation 14.7%, Zombies 11%, Post-apocalyptic 3.4%, Survival 2.4%

An evolution simulation game. Take control of your species in the environment and edit your species as a whole. Compete with other evolving species for resources on an alien planet.

Why similar: Simulation 56.8%, Sandbox 16.1%, Realistic 10.4%, Casual 7.2%, Survival 5.6%

Here is a sandbox like no other. Create massive battles with absolutely no limits. Want to see 10,000 chickens fight an army of Romans?? Sure, why not. Want to see a company of WW2 U.S soldiers fight 11,000 Medieval soldiers?? There are simply no limits to the carnage you can achieve in UEBS.

Why similar: Simulation 37.2%, Strategy 31%, Zombies 12.7%, Sandbox 10.9%, Indie 3.3%

Can you survive a zombie apocalypse? Day Zero is a text-based survival game where choices determine fate and ethical and moral decisions matter. Every choice shapes the story. Are you ready to test your limits in a zombie apocalypse?

Why similar: Outbreak Sim 66.7% ★, Zombies 13.1%, Simulation 8.3%, Post-apocalyptic 6.9%, Survival 2.7%

Expand your empire, advance your culture and go head-to-head against history’s greatest leaders. Will your civilization stand the test of time?

Why similar: Strategy 57.3%, Multiplayer 15.8%, Simulation 13.6%, Tactical 8%, Singleplayer 2.9%

Destroy Humanity with virus outbreaks, asteroid impacts and more as Planet Earth! Or team up with up to five friends as the World Leaders, Industry, Media, Scientists and Public, and try to survive. Impossible dilemmas and choices-matter create countless paths in this strategy party game!

Why similar: Outbreak Sim 78.2% ★, Strategy 13.4%, Multiplayer 8.4%

Explore a galaxy full of wonders in this sci-fi grand strategy game from Paradox Development Studios. Interact with diverse alien races, discover strange new worlds with unexpected events and expand the reach of your empire. Each new adventure holds almost limitless possibilities.

Why similar: Strategy 44.6%, Simulation 28.8%, Multiplayer 12.5%, Sandbox 9.7%, Singleplayer 2.5%

Play with evolution! Species: ALRE is a scientifically-grounded, emergent simulation of natural selection. Creatures evolve and speciate in response to in-game mutation and selection forces, allowing you to experience and tinker with evolution in real-time.

Why similar: Simulation 57.7%, Strategy 17%, Sandbox 16%, Indie 5.9%, Singleplayer 3.3%

An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam.

Why similar: Strategy 39.7%, Simulation 28.6%, Indie 13.4%, Casual 10.2%, Singleplayer 4.6%