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Games Like STEM Defense

60+ similar titles based on shared tags and player behavior. Themes include Strategy, Tower Defense, Singleplayer, Procedural Generation.

STEM Defense header art

Engage in epic battles against microscopic foes in 'STEM Defense', a strategic tower defense adventure set on a hex-grid. Harness the immune system's power, BUILD your defenses and fend off waves of pathogens, unlock potent cells and upgrades, and evolve your defenses for a grand survival showdown!

Reviews: 1 user reviews — 100% — of 1 reviews
Released: 2024-06-07
Developer: NoOneGames
Genres: Indie, Strategy
Platforms: Windows, Mac

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  1. #1 One More Tower
    97% matchNo user reviews2026
    Dev: KlartPub: Spelkollektivet
    Windows

    One More Tower is a horde survival TD set in a medieval fantasy world. Pioneer an unexplored forest, build your town and defenses, and hold out against the onslaught of enemies. How long can you survive?

    Why similar: Tower Defense 23.7%, Procedural Generation 10.9%, Roguelike 9.8%, Base Building 9.6%, Roguelite 8.3%

  2. #2 Rogue Tower
    96% matchVery Positive83% of 5,869 reviews2022
    Dev: Die of Death Games
    Windows
    Median: 10.7 hrsMean: 20.3 hrs≥1hr: 91%

    Rogue Tower is a tower defense game with roguelike elements and a continuously expanding path which you can influence. Unlock, build, upgrade, expand, defend.

    Why similar: Tower Defense 39.6%, Roguelike 14.9%, Procedural Generation 9.7%, Base Building 9%, Strategy 8.7%

  3. #3 Hexguardian
    96% matchMostly Positive79% of 691 reviews2024
    Dev: Split Second GamesPub: Yogscast Games
    Windows
    Median: 3.8 hrsMean: 9.2 hrs≥1hr: 77%

    Hexguardian is a roguelite, tower defense game where you build your own maps with hexagonal tiles! Build and upgrade towers, recruit armies, learn spells, construct wonders and place hexagonal tiles to create a path to enhance your defenses. With plenty of game modes and talents to unlock!

    Why similar: Hex Grid 28%, Tower Defense 19.9%, Roguelike 10.1%, Procedural Generation 10%, Roguelite 7.2%

  4. #4 Surging Matrix
    95% matchNo user reviews
    Dev: YX Studio
    Windows

    Upgrade and evolve, expand your territory, and build mighty defense towers to repel hordes of monsters.

    Why similar: Hex Grid 27.8%, Tower Defense 23.2%, Base Building 11.9%, Building 9.9%, Roguelite 8.2%

  5. #5 Volcano Watch
    94% matchNo user reviews2027
    Dev: Meneztan Games
    Windows

    You've been posted to a remote volcanic island with an active volcano and a mandate to monitor it. Build your station, deploy your instruments across the terrain, harvest the ressources of the fertile soil. Learn to read what the volcano is telling you, then make the call.

    Why similar: Outbreak Sim 37.2%, Hex Grid 36%, Base Building 11.4%, Strategy 6.2%, Building 4.7%

  6. #6 Monuments to Ruin
    94% matchNo user reviews
    Dev: OHNSINN
    Windows

    Build defences, explore an all-encompassing fog and pray you can fight off the massive hordes of Ruin. Engage with an expansive unlock system and survive in a world that changes with your decisions. ‘Monuments to Ruin’ is a roguelite, tower defense game set in a world ravaged by a suffocating fog.

    Why similar: Tower Defense 23.9%, Roguelike 12.3%, Procedural Generation 11%, Roguelite 8.4%, Medieval 8.3%

  7. #7 Castles on Clouds
    92% matchPositive100% of 32 reviews2024
    Dev: TJPub: Memori Studios
    Windows

    A Roguelike Tower Defense game set on a user controlled procedurally generated island. Select unique cards and relics that enhance your towers abilities, crafting powerful builds to defend against the growing hordes of enemies.

    Why similar: Tower Defense 28%, Base Building 13.7%, Roguelike 12.9%, Procedural Generation 10.2%, Roguelite 9.9%

  8. #8 Prototype TD 2
    93% match6 user reviews100% of 6 reviews2022
    Dev: Faf Games
    Windows · Mac · Linux

    Prototype TD 2 is a rogue-like tower defense game which focuses on replayability, giving the player meaningful decisions and a different experience each game. Design the route that enemies will follow and combine your tower types to adapt to a wide variety of procedurally generated maps.

    Why similar: Hex Grid 34%, Tower Defense 28.7%, Roguelite 12.1%, Strategy 10.9%, Procedural Generation 10.3%

  9. #9 Tower Knight
    91% matchPositive93% of 15 reviews2024
    Dev: Sweet Apple Games
    Windows

    Tower Knight is a deck-building & tower defense strategy game. Build your deck to strengthen your position, level up your knight, and win by capturing enemy towers.

    Why similar: Tower Defense 22.5%, Hex Grid 19.3%, Roguelike 11.2%, Procedural Generation 9.4%, Building 8.2%

  10. #10 Castle Constructor
    91% matchVery Positive81% of 74 reviews2024
    Dev: Sisyphean Games
    Windows

    Build and defend using a modular system of castle blocks. Fend off enemies who will climb over and break through your defenses. Collect new blocks and research techs to improve their strengths. From lowly soldiers to powerful siege weapons; defeat them all as you strive to protect your kingdom.

    Why similar: Hex Grid 36.9%, Tower Defense 30.1%, Medieval 10.7%, Building 10.1%, Strategy 7.4%

  11. #11 Rivet & Ruin
    90% matchNo user reviews
    Dev: Gargantua Interactive
    Windows

    A procedurally generated tower defense game. Shape creep pathing with defenses and buildings. Gather enough resources to keep up with increasingly powerful waves of creeps.

    Why similar: Tower Defense 35.1%, Procedural Generation 16.8%, Roguelike 14%, Strategy 11.7%, Base Building 10.7%

  12. #12 Tiny Kings
    89% match2 user reviews50% of 2 reviews2025
    Dev: Floating Chicken Games
    Windows

    Tiny Kings is the whimsical medieval base builder where your dreams of building and managing a pint-sized kingdom come true! Unleash your inner ruler and build your kingdom, manage your citizens' tasks, and dominate the siege to become the ultimate ruler.

    Why similar: Tower Defense 19.3%, Hex Grid 15.9%, Base Building 12%, Building 10%, Procedural Generation 10%

  13. #13 Crystal Guardians Prologue
    89% matchVery Positive93% of 76 reviews2024
    Dev: Green Pine Studios
    Windows

    Crystal Guardians prologue (small slice of the full game) is a tower defense game with rogue-like elements. Fight off waves and defend the base crystal. Gear up your towers with a powerful combination of items for your personal strategy. In a procedural map, find hidden powers and conquer the enemy.

    Why similar: Tower Defense 29.2%, Roguelike 14.6%, Procedural Generation 14%, Base Building 13.3%, Roguelite 9.9%

  14. #14 Outpost
    88% matchVery Positive87% of 789 reviews2020
    Dev: Open Mid Interactive
    Windows · Mac · Linux

    Outpost brings the perfect mix between survival and roguelite gameplay. Start the game in a randomly generated environment and try to adapt, and make it through as many nights as possible. How long can you survive?

    Why similar: Tower Defense 25.7%, Base Building 12.1%, Roguelike 12.1%, Procedural Generation 11.6%, Building 9.6%

  15. #15 Crystal Tower Defense
    87% matchMixed68% of 34 reviews2023
    Dev: Hot Roof Studios
    Windows

    Stop an endless hoard of crystal-type enemies, with different attributes, from reaching the portal to earth! You can build your own labyrinths, unlock new turrets, upgrade them, unlock abilities, and also gather permanent bonuses.

    Why similar: Tower Defense 29.7%, Procedural Generation 13.8%, Base Building 12.2%, Roguelite 10%, Building 7.8%

  16. #16 Astro company
    86% matchNo user reviews2026
    Dev: Elephant Arts
    Windows

    Defend your Core in an endless tower defense where every decision matters. Build too slow and you’re overrun. Build too fast and chaos breaks your defenses.

    Why similar: Tower Defense 30.9%, Roguelike 14.1%, Roguelite 13%, Base Building 11.7%, Strategy 10.5%

  17. #17 ThrowDown
    86% matchNo user reviews2025
    Dev: Meisel
    Windows

    ThrowDown is a familiar yet unique tower defense game with randomly generated maps, reactive mobs, and is designed for replayability.

    Why similar: Tower Defense 34.9%, Hex Grid 32.1%, Strategy 15.9%, Procedural Generation 10.7%, 3D 5.2%

  18. #18 Rogue Cube Defense
    85% matchNo user reviews
    Dev: aurimas.dev
    Windows

    Rogue Cube Defense is a minimalist roguelite tower defense game with procedurally generated path that you gradually build up. Each run is different as the upgrades you get from leveling up are random. Pick your towers loadout and come up with the best strategy to beat the hordes of enemies.

    Why similar: Tower Defense 26%, Roguelike 13%, Base Building 12.7%, Procedural Generation 12.4%, Building 8.8%

  19. #19 Crystal Guardians TD
    84% matchVery Positive88% of 115 reviews2024
    Dev: Green Pine Studios
    Windows

    Crystal Guardians is a tower defense game with rogue-like elements. Fight of waves and defend the world crystal. Gear up your towers with a powerful combination of items for your strategy. In an ever expanding map, find hidden powers and conquer the enemies.

    Why similar: Tower Defense 27.3%, Roguelike 13.2%, Procedural Generation 11.2%, Roguelite 9.7%, Base Building 9%

  20. #20 Gods Of Defense
    84% matchMostly Positive70% of 50 reviews2023
    Dev: Blue Math
    Windows

    Tower Defense Rogue-like. Defend a temple on a procedural map with variety of towers. Craft your strategy through Boon and Curse cards. With every run earn faith to upgrade the weapons. Many progression paths keep you engaged and entertained without getting stuck.

    Why similar: Tower Defense 36%, Roguelike 19.9%, Procedural Generation 18.1%, Strategy 9%, Base Building 7.3%

  21. #21 Circle TD:Defence War
    83% matchPositive86% of 14 reviews2024
    Dev: 小东马
    Windows

    A tower defense game.In the wave after wave of enemy attacks like a tide, constantly configure defense tower ties, player talents, props and equipment, build a powerful defense position, and eliminate the enemy before they fill the map!

    Why similar: Tower Defense 30%, Roguelike 14.7%, Base Building 13.9%, Building 12.1%, Roguelite 10%

  22. #22 Kingdom's Path
    82% matchNo user reviews
    Dev: Sönmez Cankurt
    Windows

    In Kingdom’s Path, each battle is your own living battlefield. Every zone you place shifts enemy flow, pushing you to adapt and outsmart them. Towers rise, leaders guide, and no run plays the same. Build, defend, and carve victory from chaos.

    Why similar: Tower Defense 24.6%, Base Building 12.9%, Roguelike 11.8%, Procedural Generation 10%, Building 8.9%

  23. #23 Eversiege
    82% matchNo user reviews2026
    Dev: Sebastian Romejko
    Windows

    Eversiege is a roguelike, tower defense in which you'll defend a castle in procedurally generated terrain. Establish a production, build defending buildings and survive waves of enemies coming from everywhere! After defeat, buy new buildings, unlock new leaders and prepare to fight again.

    Why similar: Tower Defense 24.6%, Procedural Generation 13.6%, Roguelike 12.6%, Base Building 9.8%, Roguelite 8.7%

  24. #24 Dreadful Defenders
    81% matchNo user reviews
    Dev: Erelag Studio
    Windows

    Choose an ancient deity to worship and use its power to defeat the unbelievers. Find Relics with eldritch abilities. Summon dreadful Defenders with unique traits, control the path by placing them, and combine their Benedictions to create otherworldly synergies!

    Why similar: Tower Defense 33.4%, Procedural Generation 14.5%, Strategy 14.2%, Roguelike 11.7%, Roguelite 11.5%

  25. #25 Endless Desert TD
    81% match3 user reviews67% of 3 reviews2024
    Dev: Paw Strike Games
    Windows

    Endless Desert TD is a tower defense game with roguelike elements. Carefully choose the rewards after each conquered stage, your survival will depend on it. Adapt to survive a challenging world where every playthrough is a new experience.

    Why similar: Tower Defense 38.6%, Roguelike 18.4%, Procedural Generation 17.2%, Strategy 9.3%, Survival 8.7%

  26. #26 ArcaneOutpost
    80% match4 user reviews100% of 4 reviews2024
    Dev: VortexRingGame
    Windows

    A strategy game that combines MOBA and Tower Defence, You would control guardians with different skills,building your outpost to fend off enemy attacks.

    Why similar: Tower Defense 33.1%, Base Building 18.7%, Strategy 14.2%, Building 12.2%, Tactical 6.9%

  27. #27 Kofoin - Swarm Defense
    79% matchNo user reviews2025
    Dev: Tokiko Studio
    Windows · Linux

    Kofoin is a real-time Tower Defense game where you command your swarm of bees, expand your territory, use powerful flowers to upgrade your defenses, and harness the power of Basque divinities to survive hordes of enemies

    Why similar: Tower Defense 27.4%, Hex Grid 23.8%, Procedural Generation 10%, Roguelike 9%, Roguelite 7.8%

  28. #28 Gattai TD
    79% matchNo user reviews
    Dev: Benign Games
    Windows

    Gattai TD is a roguelike, mazing tower defense in which you merge towers and gain ancient wonders to hold back waves of cursed keepsakes.

    Why similar: Tower Defense 30.1%, Base Building 16.5%, Roguelike 13.5%, Strategy 7.7%, Procedural Generation 7.2%

  29. #29 Another TD
    78% match3 user reviews67% of 3 reviews2026
    Dev: LazyDogs
    Windows

    You're the Tower Marshal at the Elderglen kingdom, and you have a terrible job. Your king really likes to send letters to neighbours. Ones that make them offended enough to send armies at your castle. They're already on the way, so get back to work!

    Why similar: Tower Defense 31.2%, Roguelike 14.9%, Base Building 13.5%, Roguelite 12.4%, Strategy 7.5%

  30. #30 Block Tower TD 2: Prologue
    78% matchPositive93% of 30 reviews2024
    Dev: MyDreamForever
    Windows

    Block Tower TD 2 is a strategic game in the roguelike style with original innovations. Build worlds from blocks, choose random upgrades, each game will be unique.

    Why similar: Tower Defense 26.6%, Roguelike 13.7%, Base Building 10.6%, Roguelite 8.7%, Strategy 8%

  31. #31 Dawn Of Defense
    77% matchNo user reviews2026
    Dev: 6side Studio
    Windows

    Dawn of Defense blends RTS, Tower Defense, and Roguelite progression. In a last defense, lead your tribe against the Empire: Command warriors in battle, fortify defenses, and build an economy as you fight to reclaim your ancestral homeland.

    Why similar: Tower Defense 23.5%, Hex Grid 18.9%, Base Building 13.3%, Procedural Generation 9.7%, Roguelite 8.3%

  32. #32 Tides of Lava
    77% matchNo user reviews
    Dev: YOXE Studios
    Windows

    A strategic tower defense roguelike game with a grid-based building system and constantly changing enemy paths and environments. Manage your builders efficiently to defend your base against a variety of enemies. Adaptiveness is the key to winning - do you have what it takes?

    Why similar: Tower Defense 32%, Roguelike 19.1%, Building 12.8%, Strategy 12.2%, Procedural Generation 11.3%

  33. #33 Terrorformer TD
    76% matchPositive89% of 27 reviews2024
    Dev: onewinter games
    Windows · Mac · Linux

    Terrorformer TD is a tower defense roguelite with a procedurally generated map that YOU shape! Raise or lower tiles, divert enemy paths and funnel monsters into perfectly designed killzones. Randomly drawn cards result in plenty of run variety, as you seek to survive endless waves of enemies.

    Why similar: Tower Defense 25.6%, Hex Grid 19.6%, Procedural Generation 13.3%, Roguelike 12.6%, Building 8.9%

  34. #34 Shrooms! Tower Defence
    75% matchNo user reviews100% of 18 reviews2025
    Dev: Terra Mater Games
    Windows · Mac

    Grow, evolve, and command a tribe of adorable mushrooms to defend your forest from axe-wielding invaders. Play across infinite procedurally generated islands, stack wild modifiers, and make every lumberjack regret picking up an axe in this 3D TD game.

    Why similar: Tower Defense 27.3%, Hex Grid 21.5%, Procedural Generation 14.1%, Nature 9.5%, Tactical 6.9%

  35. #35 Layered Loop层叠环道
    74% matchNo user reviews2026
    Dev: Zack
    Windows

    Layered Loop is a minimalist tower defense game built on stacking & evolution. Towers auto-level to boost damage/production, evolve via devouring key structures for new abilities or stat boosts. Stack towers with full effects retained, unlock global buffs at 5 layers.

    Why similar: Tower Defense 45.2%, Roguelike 14.2%, Strategy 11.3%, Base Building 10.2%, Roguelite 9.3%

  36. #36 Dofense
    75% match6 user reviews83% of 6 reviews2022
    Dev: Blue Math
    Windows

    Defend the energy cores from ever increasing enemy waves by destroying their spawn gates. Build tower mazes on Hex grid. Adapt them to dynamic changes in the terrain. Face quirky bosses. Design your own levels and share them on the Steam Workshop.

    Why similar: Hex Grid 39.9%, Tower Defense 28.1%, Building 10.4%, Tactical 7.9%, Strategy 6%

  37. #37 Twisted Tower Tactics
    73% matchNo user reviews
    Dev: Team Sämst
    Windows

    You have awoken from your century long slumber only to find out your domain has been occupied by invading forces. Drive these invaders out and reclaim what is rightfully yours in this roguelike tower defense game.

    Why similar: Tower Defense 34.5%, Roguelike 19.5%, Strategy 16.8%, Roguelite 11.7%, Procedural Generation 10.6%

  38. #38 Evil Labs
    76% matchMixed70% of 82 reviews2018
    Dev: Mirabolis Studios
    Windows
    Median: 4.3 hrsMean: 5.6 hrs≥1hr: 96%

    Evil Labs is a game about building and managing your own Evil Laboratory. Research and develop diseases, infect people, sell the cure and get rich!

    Why similar: Outbreak Sim 69.8%, Base Building 11.4%, Strategy 8.8%, Building 7%, Indie 2%

  39. #39 Creeping Dusk
    73% matchMixed67% of 94 reviews2024
    Dev: PolyShroom
    Windows · Linux

    Creeping Dusk is a tower defense game. Build a town around an abandoned gold mine and defend against monsters that swarm the area. Fortify your defenses, and prepare for the increasingly challenging nights. Will you be able to protect your town from the encroaching darkness?

    Why similar: Tower Defense 32.7%, Base Building 17.7%, Building 13%, Roguelite 11.5%, Tactical 9.9%

  40. #40 Hexual Deflection
    73% match7 user reviews86% of 7 reviews2024
    Dev: reiti.net
    Windows

    Multiplayer Tower Defense Game - Send out units and defend against enemy units in this Arena RTS with up to 32 players

    Why similar: Hex Grid 33%, Tower Defense 24.6%, Base Building 14.1%, Procedural Generation 11.2%, Tactical 6.6%

  41. #41 MINOS
    70% matchVery Positive91% of 459 reviews2026
    Dev: ArtificerPub: Devolver Digital
    Windows

    Minos is a maze-building roguelite where you, the fabled Minotaur, must defend your sanctuary from bloodthirsty adventurers. Design and re-design deadly labyrinths, set traps, and turn every brave fool into your next victim.

    Why similar: Tower Defense 28.5%, Base Building 15.3%, Roguelike 10.2%, Building 9.6%, Roguelite 9%

  42. #42 Archipelago
    74% matchMostly Positive76% of 38 reviews2022
    Dev: Isaac Lee
    Windows

    Archipelago is a roguelike tower defense game about defending randomly generated islands. Setup your defenses, manage your income, and find powerful charms to repel the enemy. Archipelago introduces tension and strategy to the tower defense genre.

    Why similar: Tower Defense 41.3%, Roguelite 14.5%, Procedural Generation 11.8%, Base Building 11.6%, Strategy 9.7%

  43. #43 Castella
    72% matchNo user reviews2026
    Dev: Slime Potion Games
    Windows

    Castella is a Tower Defense Rogue-like, where you will build a fortress to defend yourself from Hordes of monsters besieging your Castle. During the game you will unlock and upgrade a great variety of Towers and Buildings. You will build walls to block the path and defend your resources and Castle.

    Why similar: Tower Defense 27.7%, Roguelike 14%, Procedural Generation 11.6%, Roguelite 9.7%, Building 9.1%

  44. #44 Atlanta TD
    72% matchNo user reviews
    Dev: GarnetPub: Tin Man Games
    Windows · Mac

    Atlanta TD is a roguelite tower defense game where the armies of the underworld descend onto the Four Spectacular Realms in waves as it falls unto the remaining Gods to protect the city of Atlanta!

    Why similar: Tower Defense 34.4%, Strategy 12.6%, Roguelike 12.2%, Building 11.2%, Roguelite 11.2%

  45. #45 Thunder Age
    71% matchMixed62% of 28 reviews2024
    Dev: FunLinePub: Ahlman Games
    Windows

    In the flooded future world, mankind has built floating islands where electricity is harnessed during the raging thunderstorms. This unstable energy is crucial for survival, but also poses the greatest risk in this Tower Defense game.

    Why similar: Hex Grid 39.4%, Tower Defense 28.4%, Strategy 8.4%, Base Building 7.4%, Tactical 6.6%

  46. #46 Treasure's Mine!
    69% matchVery Positive100% of 51 reviews2026
    Dev: FatFishGame
    Windows

    Build defenses on randomly generated archipelagos and fend off waves of pirates! Expand land plots, combine defense towers, and collect treasures to strengthen your islands. Guard your treasures and become the wealthiest lord!

    Why similar: Tower Defense 30.7%, Hex Grid 18.9%, Roguelike 12.9%, Roguelite 12.8%, Strategy 8.7%

  47. #47 Method to Madness
    71% matchNo user reviews
    Dev: Jörn Lindner
    Windows · Mac

    Defend against waves of enemies with a strategic mix of spellcasting and tower defense. Explore new spells, towers, and artifacts in each run and discover your own playstyle in this rougelike Tower Defense game.

    Why similar: Tower Defense 30%, Base Building 17.2%, Roguelike 15.3%, Procedural Generation 12.4%, Strategy 9.5%

  48. #48 Defense of the Offensive King
    70% matchNo user reviews
    Dev: YawningCat Games
    Windows

    Save the king from hordes of angry orcs, elves, and various other fantasy races in this castle-building tower defense game. Build a maze of walls using tetromino-shaped pieces and fortify it with loyal soldiers, powerful mages, and defensive siege weapons. Can your fortress withstand the onslaught?

    Why similar: Tower Defense 41.7%, Base Building 16.9%, Roguelite 13.4%, Medieval 12.7%, Strategy 11.2%

  49. #49 Life on the Edge
    71% matchVery Positive90% of 98 reviews2022
    Dev: LOTE Team
    Windows · Mac

    Life on the Edge is an educational tower defense game. You play as a cell struggling to survive waves of bacteria and the COVID-19 virus. Protect your cell and build an understanding of cell biology at the same time!

    Why similar: Tower Defense 30.7%, Outbreak Sim 27.1%, Education 19.9%, Strategy 7.8%, Base Building 6.8%

  50. #50 Rampart
    70% matchNo user reviews2026
    Dev: Sazanami
    Windows

    Build and upgrade towers, defend your fortress from the growing onslaught. With each wave, the challenges become more difficult, but a smart strategy and the right decisions will help you endure and prevail!

    Why similar: Tower Defense 36.6%, Building 14.3%, Strategy 12.2%, Base Building 10.9%, Tactical 10.4%

  51. #51 Sushi Cat - Tower Defense
    68% matchPositive86% of 42 reviews2026
    Dev: OverPowered TeamPub: Armor Games Studios
    Windows

    Battle back waves of rogue sushi in this cute-but-chaotic roguelite tower defense! Build, upgrade, and reshape the battlefield each run.

    Why similar: Tower Defense 28.2%, Base Building 14.1%, Roguelike 14%, Procedural Generation 10.6%, Roguelite 10.6%

  52. #52 Rogue Tiles
    69% matchMixed60% of 42 reviews2024
    Dev: Possibility Paradox
    Windows

    Rogue Tiles merges tower defense with roguelike elements, offering a dynamic experience where you shape the expanding path. Unlock, build, upgrade, and defend against waves of enemies.

    Why similar: Tower Defense 33.6%, Procedural Generation 16.7%, Roguelike 16.4%, Roguelite 10.7%, Tactical 8.3%

  53. #53 Tower Dominion
    66% matchVery Positive86% of 4,988 reviews2025
    Dev: Parallel 45 Games
    Windows
    Median: 11.7 hrsMean: 21.8 hrs≥1hr: 89%

    Build and design the terrain while defending your stronghold against alien invasion in this unique Roguelike tower defense. Choose from 30 heroes, survive enemy waves, and upgrade a variety of destructive towers to hold the line!

    Why similar: Tower Defense 28.2%, Base Building 14.3%, Roguelike 12.2%, Procedural Generation 10.7%, Building 8.5%

  54. #54 Isle of Arrows
    69% matchMostly Positive79% of 1,082 reviews2022
    Dev: Gridpop
    Windows · Mac
    Median: 2.9 hrsMean: 16.1 hrs≥1hr: 68%

    Isle of Arrows is a Puzzle Tower Defense game in which you build a fortress in the sky. Place towers, expand the isle, and build your own paths. Can you find the perfect spot for each tile to beat the RNG and defend against waves of invaders?

    Why similar: Tower Defense 31.2%, Roguelike 15%, Procedural Generation 12.6%, Roguelite 8.9%, Strategy 7.4%

  55. #55 Hexistence
    67% matchNo user reviews2027
    Dev: Xufa Games
    Windows

    Hexistence is a Tower Defense Roguelike Deckbuilder. Expand a procedural map, build towers, and cast spells while managing your hand in real time. Optimize your resources to survive increasingly demanding waves!

    Why similar: Tower Defense 26.5%, Hex Grid 21.4%, Roguelike 14.8%, Procedural Generation 10.1%, Roguelite 7.4%

  56. #56 Pingdom
    67% matchNo user reviews
    Dev: Zennahoj
    Windows

    Pingdom is a Tower Defence game with endless replayability with the random terrain generation and wave system.

    Why similar: Hex Grid 34.9%, Tower Defense 25.7%, Building 11.4%, Base Building 11.3%, Nature 8.7%

  57. #57 Fortifend
    65% matchPositive91% of 35 reviews2026
    Dev: Side Crumb
    Windows

    Fortifend is a fantasy city builder with a mix of resource management and strategic tower defense. As Lord Mayor, build your settlement into a fortified city capable of fending off waves of demonic invaders. Guard the gates!

    Why similar: Tower Defense 32.5%, Base Building 21.8%, Procedural Generation 14%, Strategy 11.3%, Building 8.2%

  58. #58 Mineral Defense
    66% matchVery Positive90% of 241 reviews2024
    Dev: Corestone Games
    Windows · Linux

    Mineral Defense combines tower defense with roguelite elements and procedural generation. Build paths, unlock upgrades, and unleash powerful synergies to conquer evolving challenges in an ever-expanding world.

    Why similar: Tower Defense 27.7%, Base Building 14.7%, Roguelike 13.8%, Procedural Generation 12.1%, Roguelite 10.3%

  59. #59 Stand Your Ground
    68% match1 user reviews0% of 1 reviews2023
    Dev: Noahstar365
    Windows · Mac

    Defend attacks from enemies from all directions within a limited time. Only by making full use of the differences in each tower and choosing appropriate random rewards can you survive.

    Why similar: Tower Defense 27.6%, Roguelike 14%, Hex Grid 12.5%, Roguelite 9.1%, Building 8.7%

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