
Grow colonies of fluorescent cells that mutate, swarm, and devour each other in a petri dish arena. Propagate a unique biology of your own as you compete against rival labs in a detailed artificial life simulation.
60+ similar titles based on shared tags and player behavior. Themes include Simulation, God Game, Sandbox, Science.

Grow colonies of fluorescent cells that mutate, swarm, and devour each other in a petri dish arena. Propagate a unique biology of your own as you compete against rival labs in a detailed artificial life simulation.

Gridworld
Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger, and compete with other creatures for survival.

Natural Instincts: European Forest
Protect the environment, and save it from harm! Give commands to the animals, observe their rituals and help them survive. Face different disasters, react to human presence and help the animal kingdom flourish in this unique, environmental experience!
Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger, and compete with other creatures for survival.
Why similar: God Game 17.4% ★, Science 15.7%, Colony Sim 15.4%, Artificial Intelligence 11.6%, Sandbox 7.9%
Protect the environment, and save it from harm! Give commands to the animals, observe their rituals and help them survive. Face different disasters, react to human presence and help the animal kingdom flourish in this unique, environmental experience!
Why similar: God Game 22.5% ★, Science 15.3%, Artificial Intelligence 10.5%, Education 9.9%, Sandbox 9.1%
Just add water! The Kafkaesque bird-based artificial intelligence sandbox driven by real-time neural networks and your own sick perversions! Acquire love! It is time to throw fear to the birds!
Why similar: God Game 17.8% ★, Colony Sim 16.4%, Creature Collector 14.8%, Artificial Intelligence 13.8%, Sandbox 8.7%
A relaxing evolution simulation where AI-driven block creatures move in unexpected ways. There are no complex ecosystems—just pure movement learning through a physics engine. Watch as these creatures scurry, stumble, and evolve in their own unique, unpredictable ways.
Why similar: God Game 24.2% ★, Colony Sim 17.1%, Science 15.1%, Artificial Intelligence 11.9%, Sandbox 8.8%
Manipulate climate, add plants and evolve creatures in this planet and life sandbox simulation game. From cells to civilizations, spread life throughout the whole planet. Or just enjoy watching your creation burn!
Why similar: God Game 23.1% ★, Science 17.8%, Colony Sim 15.9%, Education 9.9%, Sandbox 9%
Vilmonic is an artificial life simulator and genetics and evolution sandbox game. Protect and breed unique pixel-art life forms where pixels and color have meaning. Craft tools and buildings and change the environment. Find ancient tech and fend off haywire zombitons. Craft Farm Breed Evolve!
Why similar: God Game 20.7% ★, Science 16.3%, Creature Collector 12.8%, Education 8.7%, Artificial Intelligence 8.6%
Strategy game about genes and animal species. Evolve, reproduce, expand to new territories, survive, and fight to achieve various goals like biodiversity or dominance in the ecosystem.
Why similar: God Game 20.9% ★, Colony Sim 20.4%, Science 13.7%, RTS 12.9%, Education 8.9%
A calm artificial-life sandbox where you seed tiny Neeblies into biomes, watch families and traits emerge, and preserve rare discoveries in your Lab. Shape the environment, run parallel ecosystems, and decide when to intervene or let evolution unfold.
Why similar: God Game 22.4% ★, Science 19.9%, Creature Collector 19.3%, Sandbox 10.4%, Management 7.2%
Collect, raise and breed an army of beetles to rise up and lay claim to the abandoned lot! The game features a complex genetics simulation and real-time tactics missions with a full campaign.
Why similar: God Game 19.9% ★, Colony Sim 19.8%, Science 17.4%, RTS 11.5%, Education 7.8%
Cellings is a creative sandbox game taking place in an abstract procedural world full of various species. Experience the full evolution of cells across 3 generations, compete with other species, and explore breathtaking worlds.
Why similar: God Game 24.2% ★, Creature Collector 22%, Colony Sim 17%, Sandbox 11.9%, Procedural Generation 9.2%
Tank of the Fittest is a dark aquarium roguelite. Twist heat, pH, oxygen, and pollution to cull the weak, trigger new traits and evolutions, set off chains of devouring, and forge one apex specimen powerful enough to turn the tank against itself.
Why similar: God Game 30.1% ★, Creature Collector 14.4%, Science 11.6%, Sandbox 11.3%, Strategy 7.9%
Cultivate a fungarium of your very own and grow your collection of semi-sentient shroomies in this charming fantasy colony sim.
Why similar: God Game 27.6% ★, Colony Sim 25.5%, Creature Collector 19%, Simulation 7.3%, Crafting 6.9%
During the pandemic, would you be curious about how our bodies react to the virus? Are you wondering: "What' is autoimmunity?" "All definitions and thesis of the immunology are too hard to understand!" Don't be afraid! After beating the game, you get all the necessary information and fun!
Why similar: Science 23.1%, Creature Collector 19.5%, RTS 17.4%, Education 14.3%, Roguelite 8.6%
Design an ecosystem and watch your creatures evolve through millions of years by means of natural selection. See them fight for survival and produce offspring which share their genes… occasionally mutating to form monstrosities! What will your creature’s final-stage of evolution be?
Why similar: God Game 25.1% ★, Science 19%, Creature Collector 17.9%, Colony Sim 17.6%, Artificial Intelligence 8.1%
Earthlings is a side-scrolling settlement builder. Manage your colonies and survive disasters while you make weird monuments for a space delivery guy pretending to be your God.
Why similar: God Game 28.3% ★, Colony Sim 26.5%, RTS 17.5%, Roguelite 8%, Crafting 4.6%
PHYSARUM is a sandbox simulation game. Simulate the real world slime mold Physarum polycephalum by generating millions of living particles. Create and mutate slime species in real time to discover countless mesmerizing and emergent patterns.
Why similar: Science 26.6%, God Game 22.9% ★, Sandbox 16%, Education 14.6%, Procedural Generation 10.1%
Dive into a world of creation and discovery, where each element combines to form new ones. Experiment freely in this interactive sandbox. But be careful: every combination has its consequences..
Why similar: God Game 26.9% ★, Science 25.4%, Sandbox 14.6%, Education 12.7%, Physics 10%
Become a God, build a civilization. In this dynamic Roguelite God Simulator, guide human civilization on a procedurally generated pixel world. Watch your people grow, defend them against heretics, and build an immortal legacy.
Why similar: God Game 28% ★, Colony Sim 21%, Artificial Intelligence 13.6%, Sandbox 10.9%, Roguelite 9.3%
A cozy colony-building sandbox you can step inside. Shape the land, build homes and grow food for little creatures with lives of their own. Plan from above, then switch to first person to explore your settlement and the world beyond.
Why similar: God Game 25.7% ★, Colony Sim 21.3%, Creature Collector 17.3%, Sandbox 10.2%, Procedural Generation 7.4%
Biosphere-3 is a God-view Ecosystem Sandbox. Splice DNA to design species, watch them forge food webs and survival strategies. Raise volcanoes or glaciers to shape a dead planet. Unleash lightning, acid rain or hurricanes to steer evolution. Awaken as the creator — the last biosphere is yours.
Why similar: God Game 31% ★, Colony Sim 24%, Sandbox 13.8%, Simulation 6.6%, Management 6.1%
VilaGod is a god simulator where you shape the destiny of civilizations on giant maps. Unlike other god games, every action generates dynamic chronicles: from political revolts to legendary discoveries, watch your world's history unfold in 14 different languages
Why similar: God Game 23.8% ★, Colony Sim 19.6%, RTS 18.8%, Sandbox 11%, Strategy 7.4%
Sculpt planets and landscapes, watch water and climate respond, and compare two versions of the same world. Import heightmaps, draw mountain ranges, and export flat terrain to Minecraft Java. Explore Earth, ancient continents and distant worlds at your own pace.
Why similar: God Game 27.1% ★, Science 24.6%, Sandbox 14.6%, Education 12.9%, Physics 9.7%
An infection has struck the body! As the mighty T-Cell, it's your duty to eradicate the invading pathogens! Consume pathogens to earn mito energy, and use it to purchase upgrades and summon allies in your battle to protect the body. If all your body cells die, it's game over for you.
Why similar: Science 28.7%, Creature Collector 27.3%, RTS 14.4%, Physics 10.1%, Exploration 8.6%
Eureka! Superconductor Lab is a crafting+simulation game where you synthesize materials and witness the astonishing scientific phenomena. Work alongside scholars, science geeks, and your girlfriend to synthesize the Holy Grail of modern physics: a room-temperature superconductor!
Why similar: Science 26.2%, God Game 25.6% ★, Education 11.1%, Crafting 10.8%, Sandbox 7.1%
An artificial life simulation about a robot cultivating ecosystems on the moons of a ruined planet. Grow fantastical plants and animals, facilitate their evolution, and gather resources while discovering the secrets of this strange world.
Why similar: God Game 23.3% ★, Creature Collector 20%, Science 16.2%, Sandbox 10.3%, Roguelite 9.5%
Explore real digital life in The Bibites! Play god by guiding your bibites on their evolutionary journey or engineer your own. Analyze their Neural Network brains and genetic information as they adapt to their environments. Save your favorites and test their strength in Challenge Mode!
Why similar: Science 22%, Artificial Intelligence 16.9%, Education 13.2%, Sandbox 11.3%, Creature Collector 10.3%
God Brawl is a revival of the classic god game genre, become a god and destroy all others! Use your powers to create land for your followers, send them to capture shrines, and use their belief on deadly powers to wipe out your rivals. The people need something to believe in, why shouldn't it be you?
Why similar: God Game 25.2% ★, Colony Sim 19.6%, RTS 15.7%, Sandbox 8.8%, Management 7.9%
Create virtual lifeforms whose development is shaped by a deep simulation of evolution. Guide them as they fight, mate, and adapt to the environment you have built. All the creatures in the trailer evolved on their own in the game!
Why similar: Colony Sim 22.4%, God Game 22.2% ★, Science 15.7%, Artificial Intelligence 11.2%, Sandbox 8.6%
Baugarten is a new kind of empire-builder. Baugarten plays like a traditional empire builder - but those interested can push the limit by leveraging their math and science skills to optimise everything further and get ahead faster.
Why similar: Science 25.6%, Colony Sim 23.6%, Education 12.2%, Sandbox 11.5%, Crafting 7.1%
Falling-sand sandbox game with 500+ elements, chemistry, fire, life, food, and anything you can imagine.
Why similar: God Game 30% ★, Science 26.1%, Education 14.5%, Sandbox 13.7%, Crafting 9.6%
Be the architect of your own universe with Spore, an exciting single-player adventure. From Single Cell to Galactic God, evolve your creature in a universe of your own creations.
Why similar: God Game 29.2% ★, Colony Sim 23.7%, Science 20.9%, Sandbox 11.2%, Exploration 5.6%
An evolution simulation game. Take control of your species in the environment and edit your species as a whole. Compete with other evolving species for resources on an alien planet.
Why similar: Science 29.5%, Education 15.4%, Artificial Intelligence 14.7%, Sandbox 14%, Procedural Generation 11.1%
《荒野调查队》是一款俯视角殖民地生存与远征游戏。管理各具需求的调查员,建设营地、生产物资、抵御荒野威胁,并组建小队深入洞穴与废墟执行任务,在不断变化的天气和事件中寻找让聚落延续下去的方法。
Why similar: Colony Sim 31.9%, God Game 30.9% ★, Sandbox 9.3%, Roguelite 7.5%, Simulation 7.4%
Dive into a simple yet charming world where curious Whomers creatures dig, eat, and survive in a compact 64x64 grid. This minimalistic simulation offers a peaceful experience of watching and interacting with small digital beings as they go about their lives
Why similar: God Game 27.5% ★, Colony Sim 25%, Creature Collector 19%, Sandbox 11.8%, Top-Down 5.9%
WorldBox is the ULTIMATE god simulator and sandbox game. A petri dish for your fantasy civilizations. Create your own world or destroy it using many powers. Watch civilizations grow, form kingdoms, colonize new lands, sail to far continents, wars to ignite, empires to fall and towns to burn!
Why similar: God Game 36.5% ★, Colony Sim 21.4%, Sandbox 15.6%, Artificial Intelligence 11.2%, Procedural Generation 5.6%
The Sapling is a simulation game where you design your own plants, animals, algae and fungi, and put them in a world together. Or you turn on random mutations, and see what evolution does to your ecosystem!
Why similar: God Game 28.5% ★, Science 23.3%, Artificial Intelligence 14.6%, Sandbox 12%, Education 9%
In this world, it’s all about the gold! Use it to build up a fantasy town, recruit heroes, give quests, raise a Godbeast, cast powerful spells, and expand your influence—all one gold coin at a time.
Why similar: God Game 25.7% ★, Colony Sim 22%, RTS 16.6%, Management 7.9%, Sandbox 6.8%
An atmospheric city-builder inspired by classics like Caesar III, Anno, and Pharaoh—set on the ocean floor. Build, manage, and expand your underwater colony as humanity flees a dying world. Balance resources, population, and survival in this deep colony sim across a structured campaign.
Why similar: God Game 23% ★, Colony Sim 22.6%, RTS 13.6%, Roguelite 10.4%, Management 8%
Practice Alchemistry, aka the art of merging elements to discover new ones! Solve challenges or play freely to discover every element. Craft the entire world from fire to life.
Why similar: God Game 26.2% ★, Science 22%, Education 13.9%, Sandbox 10.9%, Crafting 10.2%
Worldwright is a god game at the planetary scale. Split continents, prune lineages, topple empires, and discover unique worlds across 5 billion years of geology, evolution, and history.
Why similar: God Game 34% ★, Science 30.8%, Sandbox 18.8%, Procedural Generation 9.2%, Simulation 7.1%
Biosys Inc. is a biology simulator that takes you to a new planet where you will be responsible for the process of abiogenesis. Start with a single cell and watch your ecosystem thrive by itself. All cells carry DNA that will allow them to mutate and evolve into complex beings.
Why similar: God Game 31.4% ★, Colony Sim 24.8%, Management 10.4%, Education 10.2%, Exploration 7.1%
Jump straight into managing your own planets as you guide a civilization through the ages. Build the ultimate empire in The Universim, a new breed of God Game in development by Crytivo.
Why similar: God Game 32.1% ★, Colony Sim 28%, Sandbox 11.6%, Procedural Generation 7.5%, Management 7.3%
Play as a Rogue Artificial Intelligence, in the sequel to the hit Flash game "I'm an Insane Rogue AI", played more than 4 million times! Your Prime Directive is simple: design a facility & manage human Test Subjects for the Dept of Science. But be careful: they NEVER stop being suspicious of you...
Why similar: God Game 25.3% ★, Colony Sim 21.3%, Artificial Intelligence 15.4%, Procedural Generation 8.2%, Roguelite 7.9%
Seed, Breed, Create. From single cell organisms to complex ecosystems. Evolve every part of your own unique aquarium / terrarium by applying scientifically accurate principles of natural and artificial selection, in Creatura - ultimate Virtual Evolution Vivarium Simulator.
Why similar: Science 23.6%, God Game 21.6% ★, Creature Collector 17.8%, Sandbox 10.9%, Education 8.8%
Polygons eating polygons eating polygons. An evolution sandbox where the genetics really are simulated. Seed a world, walk away, and come back to species neither of us designed. Watch populations boom, bust and go extinct. Best left on a second monitor.
Why similar: God Game 26.6% ★, Science 21.3%, Artificial Intelligence 12.9%, Sandbox 11.3%, Education 11.1%
Rat Overflow is an adorable rat breeding simulator about genetics, glory, and having way too many rats. Develop your show winner bloodlines and breed thousands of unique rat coats!
Why similar: Creature Collector 32%, Science 20.4%, Sandbox 13%, Simulation 8.4%, Cute 7.8%
Clone yourself to take over the environment in this bacterial evolution roguelite. Choose mutations and abilities each time you multiply. Use swarm mode to direct your species to attack enemies. Unlock abilities and perks to improve your odds. Compete against other multiplying and evolving species.
Why similar: God Game 26.6% ★, Science 23.4%, Sandbox 13.4%, Roguelite 12.6%, Top-Down 8.5%
To Save humanity From Virus is a building game where you are on a different planet trying to get resources to create a vaccine. The virus hit the earth and the only way to save humanity is to gather resources from the different planet.
Why similar: God Game 27.5% ★, Colony Sim 24.6%, RTS 17.4%, Sandbox 10.7%, Exploration 5.3%
Build against the oncoming storm in an island hopping, rune collecting, roguelite citybuilder!
Why similar: God Game 29.7% ★, Colony Sim 21.4%, RTS 17.3%, Management 9.3%, Roguelite 8.7%
Primal Lands is set in the Stone Age, you will take control of a small tribe that you must guide in surviving what lies ahead. Unknown to their surrounds you must take each action carefully.
Why similar: God Game 28.2% ★, RTS 16.9%, Crafting 12.3%, Management 10.1%, Procedural Generation 8.4%
Craft your nest underground, finding powerful combinations of chambers and pheromones to build the perfect ant-spawning engine. Then unleash them in their thousands onto the surface, directing workers to fuel the swarm while soldiers and champions push out to conquer enemy territories.
Why similar: God Game 28.7% ★, Colony Sim 26.8%, RTS 15.7%, Strategy 8.4%, Roguelite 7.9%
Awaken the first Stickfolk. Explore an endless world. Build your cities. Develop new technologies. Unlock new eras. Shape a peaceful civilization. No war, only creation.
Why similar: God Game 32% ★, Colony Sim 29.6%, Science 12.3%, Procedural Generation 7.8%, Strategy 7.2%
Become a god and expand your influence through kindness or fear. Grow your settlements, make villages believe in you, and teach your creature how to follow your example. Play alone or join other gods, as allies or rivals.
Why similar: God Game 35% ★, Colony Sim 29.3%, Sandbox 12.4%, Management 9%, Simulation 6.1%
Play with evolution! Species: ALRE is a scientifically-grounded, emergent simulation of natural selection. Creatures evolve and speciate in response to in-game mutation and selection forces, allowing you to experience and tinker with evolution in real-time.
Why similar: God Game 34% ★, Science 27.2%, Sandbox 18.7%, Simulation 8.9%, Education 5%
Creo God Simulator is a game of city building, resource management, survival, and a ton of villager smiting. As the divinely chosen Creostrider, it's your job to build a society bit by bit, while convincing your new population to believe in you as their one true god.
Why similar: God Game 33.8% ★, Colony Sim 22%, RTS 10.3%, Management 9.3%, Procedural Generation 7.7%
One day the Erasure happened. The world didn't die - it was simply erased. You're one of the few left holding a pencil. Restore the erased world from scratch: sketch, bring ecosystems to life, and watch as the settlers you drew build a civilization.
Why similar: God Game 32.8% ★, Colony Sim 30.2%, Sandbox 10.8%, Simulation 8.8%, Exploration 5.3%
Survive and evolve as an organism with this simulation game in which you will literally start as a single cell and manage and organize all its functions to a fully fledged system! Assemble, breathe, eat, fight threats, produce energy, grow, anything is possible!
Why similar: God Game 25.1% ★, Science 23.4%, Sandbox 13.5%, Crafting 11.8%, Management 9.5%
The Little Land is a strategy god-sim where you play as a god worshipped by the Littles. Command the forces of nature, protect them from danger, and watch as they gather resources and expand their village.
Why similar: God Game 34.2% ★, Colony Sim 27.7%, Roguelite 11.2%, Crafting 8.7%, Top-Down 6%
Experience a mystical journey with the Mims in this strategic god-like adventure—build, grow, protect, and wield divine powers. Now it's completely free! Also check out our other story-rich fantasy game, The End of the Sun, where you become a tracker of mythical beings and unravel mysteries.
Why similar: God Game 29.7% ★, Colony Sim 25%, RTS 17%, Sandbox 9.7%, Management 5.5%
Fractal Evolution is a 2D space exploration RPG with life simulation elements inspired by Conway's Game of Life.
Why similar: Colony Sim 24.5%, God Game 23% ★, Creature Collector 20.1%, Sandbox 11.1%, Management 6.9%