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Games Like PHYSARUM: Slime Mold Simulator

60+ similar titles based on shared tags and player behavior. Themes include Science, Simulation, Education, Sandbox.

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  1. #1 Aggi's Tiny Friends
    97% match3 user reviews100% of 3 reviews2025
    Dev: Autumn SeniorPub: OST Senior
    Windows

    Join Aggi and dive into a world that lies just out of sight. Customize your own cell and see it thrive in a vibrant ecosystem. Discover a wide variety of organisms like you've never seen before. And learn real science in a playful and relaxed environment.

    Why similar: Science 41.7%, Education 22.6%, Sandbox 15.9%, Simulation 12.6%, Casual 5.9%

  2. #2 Substrate: Emergence
    96% matchNo user reviews2026
    Dev: Petri Dish Games LLC
    Windows

    Grow fluorescent cells that create mesmerizing emergent chaos. Simple mechanics hide deep complexity as cells evolve survival strategies through synergistic interactions. Catalogue successful lines and culture them to develop your own unique biology.

    Why similar: God Game 25.5%, Sandbox 16.7%, Simulation 15.8%, Science 14.6%, Education 11.5%

  3. #3 Alchemy Laboratory: Simulator
    96% match5 user reviews100% of 5 reviews2025
    Dev: Afk Pixel Studio
    Windows

    Dive into a world of creation and discovery, where each element combines to form new ones. Experiment freely in this interactive sandbox. But be careful: every combination has its consequences..

    Why similar: Science 29.7%, God Game 20.9%, Sandbox 19.8%, Education 15.6%, Simulation 10.1%

  4. #4 Species: Artificial Life, Real Evolution
    95% matchMostly Positive74% of 988 reviews2018
    Dev: Quasar
    Windows · Mac · Linux
    Median: 2.3 hrsMean: 8.6 hrs≥1hr: 63%

    Play with evolution! Species: ALRE is a scientifically-grounded, emergent simulation of natural selection. Creatures evolve and speciate in response to in-game mutation and selection forces, allowing you to experience and tinker with evolution in real-time.

    Why similar: Science 29.9%, God Game 24%, Sandbox 23.7%, Simulation 15.3%, Education 5.8%

  5. #5 Sandboxels
    94% matchVery Positive95% of 844 reviews2025
    Dev: R74n
    Windows · Mac
    Median: 1.8 hrsMean: 3.4 hrs≥1hr: 60%

    Falling-sand sandbox game with 500+ elements, chemistry, fire, life, food, and anything you can imagine.

    Why similar: Science 30.3%, God Game 23.5%, Sandbox 18.4%, Education 17.8%, Simulation 6.1%

  6. #6 Virtual Chemistry Lab
    93% match1 user reviews100% of 1 reviews2023
    Dev: Alpay Akay
    Windows

    This is a serious game. Made for educational purposes. It was made in order to enable students to understand the high school chemistry curriculum and to provide equality of opportunity.

    Why similar: Science 34%, Education 27.2%, Sandbox 20.1%, Simulation 17.5%, Indie 0.8%

  7. #7 pan·gaia
    92% matchNo user reviews
    Dev: Alex Laing
    Windows · Linux

    pan·gaia is a whole-Earth sandbox fresh outta 1999. Sculpt your planet's climate, balance its ecology, design the perfect species for a niche, and maybe, lead them to sapience. Or... hurl meteors at them.

    Why similar: Sandbox 29.4%, Science 26.5%, God Game 23.1%, Simulation 14.1%, Abstract 6.5%

  8. #8 Atoms and Time
    91% match8 user reviews88% of 8 reviews2023
    Dev: Brain Ranch Games
    Windows

    Survive, evolve, and adapt in a rapidly changing world. Survive the test of time, and become an integral part of your world's biosphere. Or play God and build a full ecosystem in seconds.

    Why similar: Science 38.1%, Education 22%, Simulation 19%, God Game 12.8%, Procedural Generation 7.6%

  9. #9 Planetary Life
    90% matchOverwhelmingly Positive95% of 743 reviews2025
    Dev: Sotenbox
    Windows
    Median: 3.5 hrsMean: 7.9 hrs≥1hr: 86%

    Manipulate climate, add plants and evolve creatures in this planet and life sandbox simulation game. From cells to civilizations, spread life throughout the whole planet. Or just enjoy watching your creation burn!

    Why similar: Science 27.4%, God Game 24.6%, Sandbox 16.4%, Procedural Generation 10.7%, Education 10.3%

  10. #10 Natural Instincts: European Forest
    91% matchMixed47% of 289 reviews2021
    Dev: DreamStorm StudiosPub: Games Operators
    Windows
    Median: 36 minMean: 2.3 hrs≥1hr: 36%

    Protect the environment, and save it from harm! Give commands to the animals, observe their rituals and help them survive. Face different disasters, react to human presence and help the animal kingdom flourish in this unique, environmental experience!

    Why similar: Science 23.7%, God Game 23.2%, Sandbox 16.2%, Education 16.1%, Procedural Generation 8.9%

  11. #11 Thrive
    89% matchVery Positive92% of 1,599 reviews2021
    Dev: Revolutionary Games Studio
    Windows · Mac · Linux
    Median: 2.1 hrsMean: 6.2 hrs≥1hr: 66%

    An evolution simulation game. Take control of your species in the environment and edit your species as a whole. Compete with other evolving species for resources on an alien planet.

    Why similar: Science 34.1%, Education 18.9%, Sandbox 18.7%, Procedural Generation 12.2%, Simulation 12%

  12. #12 THE UNIVERSE
    89% match3 user reviews33% of 3 reviews2020
    Dev: Enrique Salvador
    Windows

    Feel like you are in space ! This application has been created in a photorealistic way, you will feel like you are on Mars, Jupiter, Mercury ... and ISS ! The best education game. If you like astronomy this is your application. You will feel that you are in space observing the entire universe.

    Why similar: Science 40.7%, Education 25.3%, Simulation 21%, Casual 12.1%, Singleplayer 0.9%

  13. #13 Tyto Ecology
    88% matchMostly Positive76% of 434 reviews2016
    Dev: Immersed Games
    Windows · Mac

    Build your biome! With an empty biodome as your canvas, add plants and animals from three different ecosystems. Observe interactions like hunting, blooming, and even decomposing! Will your biodome last for decades, or will it experience a total ecosystem collapse? You’re in control!

    Why similar: Science 41.9%, Simulation 26%, Education 24.2%, Casual 5.1%, Indie 2.8%

  14. #14 The Sapling
    87% matchVery Positive90% of 1,846 reviews2019
    Dev: Wessel Stoop
    Windows · Linux
    Median: 3.9 hrsMean: 11.7 hrs≥1hr: 86%

    The Sapling is a short simulation game where you design your own plants and animals, and put them in a world together. Or you turn on random mutations, and see what evolution does to your ecosystem!

    Why similar: Science 28.1%, God Game 22.6%, Sandbox 16.4%, Education 11.6%, Procedural Generation 9.8%

  15. #15 Wuli Sandbox
    86% matchNo user reviews
    Dev: Happy百万
    Windows

    In this physics-based particle sandbox, everything is in flux: water, steam, ice, magma, acid... Blast it. Wreck it. Build it!

    Why similar: Science 34.1%, Sandbox 23.6%, God Game 19.5%, Simulation 15.2%, Casual 5.1%

  16. #16 Chimp Memory
    86% matchPositive94% of 17 reviews2024
    Dev: Windmill's Light
    Windows

    Chimp Memory is a logical puzzle game and memory challenge. Take on the same tests faced by lab monkeys and prove your memory skills are sharper than theirs. Can you outperform the primates? Test yourself and find out!

    Why similar: Science 43.3%, Education 31.2%, Simulation 15.2%, Casual 6.4%, 2D 2.2%

  17. #17 Universe Sandbox
    85% matchOverwhelmingly Positive96% of 30,587 reviews2015
    Dev: Giant Army
    Windows · Mac
    Median: 2.4 hrsMean: 23.5 hrs≥1hr: 71%

    Create & destroy on an unimaginable scale with a realistic physics-based space simulator. Explore the beauty of our universe and the fragility of our planet. Use science to bend the laws of gravity, collide planets, boil away oceans, fire epic space lasers, and customize your universe.

    Why similar: Science 30.5%, Sandbox 23.5%, God Game 17.2%, Education 12.8%, Simulation 11.5%

  18. #18 Eureka! Superconductor Lab
    84% matchNo user reviews
    Dev: GomulGames
    Windows

    Eureka! Superconductor Lab is a crafting+simulation game where you synthesize materials and witness the astonishing scientific phenomena. Work alongside scholars, science geeks, and your girlfriend to synthesize the Holy Grail of modern physics: a room-temperature superconductor!

    Why similar: Science 33.9%, God Game 22%, Education 15.2%, Simulation 11%, Sandbox 10.7%

  19. #19 Nanoscape
    84% matchMixed60% of 20 reviews2021
    Dev: 3D Visualisation Aesthetics Lab
    Windows

    A first person exploration of a cancer cell deep in the human body, featuring a highly detailed simulation of cellular anatomy and processes based on the latest scientific research!

    Why similar: Science 40.6%, Education 27.2%, Simulation 20.9%, Casual 8.5%, Atmospheric 2.3%

  20. #20 GeneEvolution
    83% matchNo user reviews
    Dev: SingularPixel
    Windows

    Gene Evolution is a game that simulates the microscopic world. You can design unique cells, edit their attributes, functions, and intelligence. Then release them into the microscopic world and watch them forage, reproduce, compete, and continually evolve through mutations.

    Why similar: Simulation 22.9%, Sandbox 22.3%, Science 21.4%, Education 14.7%, Procedural Generation 8.2%

  21. #21 Chemistry My Love
    82% matchNo user reviews
    Dev: SPIN Software
    Windows

    Chemistry My Love is the ultimate gamified educational tool for high school and college level chemistry. Balance chemical reaction coefficients, masses and concentrations, with step-by-step explanations. Level up your knowledge playing chemical games and solving computer-generated quizzes.

    Why similar: Science 37.4%, Simulation 32.7%, Education 25.4%, Indie 4.4%

  22. #22 Project Chemistry
    82% matchMostly Positive76% of 212 reviews2021
    Dev: Ata TürkoğluPub: Espale Studios
    Windows
    Median: 3.6 hrsMean: 26.4 hrs≥1hr: 88%

    Interact with elements and molecules in a way that you have never before! Observe them and make them react with each other in the sandbox mode. Synthesize every molecule in the quest mode. Discover countless macromolecules and the elegancy of chemistry.

    Why similar: Science 36.6%, Education 21.2%, Sandbox 15.1%, God Game 14.4%, Simulation 9%

  23. #23 FireStarter 2
    81% matchPositive96% of 23 reviews2024
    Dev: Arthur Giraud
    Windows

    FireStarter 2 is a simplified forest fire simulation game that offers a first approach to fire science for all.

    Why similar: Science 38.7%, Sandbox 25.5%, Simulation 23%, Procedural Generation 11.3%, Indie 0.9%

  24. #24 Creatura
    81% matchMixed68% of 228 reviews2021
    Dev: Koksny.com
    Windows · Linux
    Median: 30 minMean: 8.3 hrs≥1hr: 35%

    Seed, Breed, Create. From single cell organisms to complex ecosystems. Evolve every part of your own unique aquarium / terrarium by applying scientifically accurate principles of natural and artificial selection, in Creatura - ultimate Virtual Evolution Vivarium Simulator.

    Why similar: Science 29.7%, God Game 18.2%, Sandbox 16%, Education 11.7%, Simulation 9.8%

  25. #25 Size Matters
    80% matchVery Positive87% of 509 reviews2021
    Dev: Mazen GamesPub: GrabTheGames
    Windows
    Median: 1.9 hrsMean: 2.8 hrs≥1hr: 69%

    You play as a scientist who is shrinking every second in a race against time! Find all the ingredients and formulas scattered around the laboratory, which are necessary for producing the life-saving antidote. But beware, your time is very precious.

    Why similar: Science 37%, Education 22.3%, Sandbox 19.1%, Simulation 12%, Casual 4.3%

  26. #26 Terra Firma 2
    78% matchVery Positive89% of 103 reviews2025
    Dev: Working as Intended
    Windows

    Shape breathtaking worlds in Terra Firma 2, a vast simulation where your creations evolve through the forces of nature. Sculpt the land, then watch as weather, erosion, and life itself transform your world into a dynamic, living ecosystem- right down to every plant and creature.

    Why similar: God Game 30.9%, Science 24.7%, Sandbox 23.2%, Simulation 13.5%, Atmospheric 3%

  27. #27 Vilmonic
    79% matchMostly Positive72% of 85 reviews2018
    Dev: Bludgeonsoft
    Windows · Mac · Linux

    Vilmonic is an artificial life simulator and genetics and evolution sandbox game. Protect and breed unique pixel-art life forms where pixels and color have meaning. Craft tools and buildings and change the environment. Find ancient tech and fend off haywire zombitons. Craft Farm Breed Evolve!

    Why similar: Science 26.3%, God Game 22.2%, Sandbox 16.1%, Education 14.9%, Simulation 9.3%

  28. #28 The Sandbox
    79% matchMixed55% of 571 reviews2015
    Dev: PIXOWL INC.
    Windows
    Median: 1.2 hrsMean: 5.5 hrs≥1hr: 55%

    READY FOR CRAFTING VIRTUAL WORLDS ON YOUR PC?The acclaimed world-building game featuring a unique mission-based approach is coming onto PC via Steam Early Access. With over 16 million players on mobile & tablets versions and 1,500,000 pixel blocks creations shared in the Online Gallery to date, this PC version is taking world...

    Why similar: Sandbox 50.7%, God Game 27.1%, Simulation 15.5%, Casual 4.2%, Indie 1.8%

  29. #29 Solarium
    78% matchMixed69% of 130 reviews2017
    Dev: Sunfleck Software
    Windows
    Median: 30 minMean: 8.8 hrs≥1hr: 37%

    Challenge yourself. What do you really know about plants? Want to find out? And win some points to build your own custom plants? Then welcome to Solarium!

    Why similar: Science 41.8%, Education 29.4%, Simulation 26.8%, Indie 2%

  30. #30 Mission To Fission
    76% matchPositive100% of 20 reviews2025
    Dev: Higgsino
    Windows · Linux

    Nuclear fission simulator. Control A nuclear reactor, balancing Uranium fissile material. The game features a oversimplified reactor and the R.B.M.K Reactor in Chernobyl.

    Why similar: Education 36.5%, Simulation 29.9%, Sandbox 29.6%, 2D 3%, Singleplayer 0.9%

  31. #31 Orbit Simulator
    77% matchNo user reviews
    Dev: Tonia Sanzo
    Windows

    Space Simulator and Music Machine!

    Why similar: Science 36%, Simulation 17.9%, Education 16.8%, Sandbox 14.2%, Casual 7.5%

  32. #32 Gridworld
    77% matchVery Positive86% of 243 reviews2015
    Dev: DopplerFrog
    Windows · Linux
    Median: 3.8 hrsMean: 5.6 hrs≥1hr: 84%

    Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger, and compete with other creatures for survival.

    Why similar: Science 27.8%, God Game 20.5%, Sandbox 16.2%, Education 12.5%, Procedural Generation 11.7%

  33. #33 Galimulator
    76% matchVery Positive91% of 497 reviews2018
    Dev: Snoddasmannen
    Windows · Mac · Linux
    Median: 1.6 hrsMean: 9.8 hrs≥1hr: 68%

    Galimulator is a galactic empire simulation and sandbox game. See how Empires rise and fall, and how the people in them climb through the ranks to bring prestige to their Dynasty. Then throw in an invasion of self replicating Smatter monsters if you want to spice things up.

    Why similar: Simulation 40.9%, God Game 30.6%, Sandbox 28.5%

  34. #34 Antbox
    75% matchNo user reviews
    Dev: nonanonanonanonanonanona
    Windows

    Customize your own ant colony. Test its viability against starvation and predation. Pit rival colonies against each other and see who comes out on top. Do you like to watch ants go about their day?

    Why similar: God Game 33.4%, Sandbox 28.6%, Simulation 18.4%, Procedural Generation 9.8%, Casual 7.5%

  35. #35 Mini Eco
    75% matchNo user reviews
    Dev: OHyatsu
    Windows

    MiniEco is a cozy top-down nature sim that combines laid-back idle gameplay, hands-on ecosystem management, and a hint of god-like power. Nurture or disrupt evolving species, shape their habitats, and watch as thousands of organisms adapt—or clash—in real time.

    Why similar: Science 35.7%, God Game 26.6%, Sandbox 23%, Simulation 11.6%, 2D 1.6%

  36. #36 GalactiWar - Empire Simulator
    74% matchNo user reviews2026
    Dev: Silver
    Windows

    Watch empires rise and fall, or intervene with godly powers, in GalactiWar, a space empire simulation sandbox game.

    Why similar: God Game 28.3%, Sandbox 24%, Science 23.5%, Simulation 16.9%, Procedural Generation 6.4%

  37. #37 Jingjie: Signals
    73% match2 user reviews100% of 2 reviews2026
    Dev: JK Studio
    Windows

    Jingjie: Reject grinding. Embrace chaos. Victory isn't won by memorizing formulas, but by scripting robust laws to tame the probability cloud. Here, you write the rules of nature. From simple logic, complex life emerges. Observe. Experiment. Evolve.

    Why similar: God Game 30%, Science 20.6%, Sandbox 18.2%, Simulation 12.8%, Procedural Generation 9.4%

  38. #38 Apples Gone Wild Simulator 2025
    73% matchNo user reviews
    Dev: OnTriggerJoy
    Windows

    Apples Gone Wild Simulator lets you play mad scientist with apple DNA. Plant mutated apples, grow experimental trees, and uncover delightfully strange traits from musical fruit to apples that stare into your soul.

    Why similar: Sandbox 29%, Simulation 27.9%, Science 25.1%, Casual 9.4%, Atmospheric 4%

  39. #39 Pretty Buttons
    74% matchNo user reviews2025
    Dev: Valkyrja GamesPub: EINHERJAR ENTERPRISES LLC
    Windows

    Pretty Buttons makes the buttons on your keyboard do pretty things. Its a visual sensory experience to engage any who need a little engagement.

    Why similar: Education 30%, Sandbox 29.6%, Simulation 27.1%, Casual 11.1%, Indie 1.3%

  40. #40 Parametric Creature: Lab
    73% matchPositive97% of 32 reviews2021
    Dev: Ni Hao
    Windows · Mac

    Explore and create parametric creatures

    Why similar: Science 26.4%, Sandbox 21.2%, Procedural Generation 14.4%, Simulation 13.4%, Education 12.7%

  41. #41 Reactonix Sandbox
    72% matchNo user reviews
    Dev: Dark Games DGG
    Windows · Linux

    Reactonix is a flexible and enjoyable simulation sandbox where every force is at your command. Create ecosystems alone or with friends, experiment with physics and watch life evolve—or start an apocalypse for the sake of science. Complete freedom to create and destroy is in your hands.

    Why similar: Science 35.7%, God Game 26.9%, Sandbox 23.9%, Simulation 12.5%, Indie 0.6%

  42. #42 Sand in a Box
    71% match7 user reviews71% of 7 reviews2024
    Dev: Tiliasoft.com
    Windows · Linux

    Sand in a Box is a 'falling sand' game that simulates thermal flow, electricity, radioactive decay, and gravity. Create art, experiment with physics, and craft your own simulation rules with user-friendly mod support!

    Why similar: Science 30.4%, God Game 22.2%, Education 17.5%, Sandbox 16.8%, Simulation 8.4%

  43. #43 EvoLife
    72% matchPositive86% of 28 reviews2022
    Dev: Mihaly Sisak
    Windows

    Create and evolve your own digital lifeforms! Watch or interact as your creations adapt and thrive in a world governed by the laws of physics. Download now and start your own evolutionary journey!

    Why similar: Science 29.7%, God Game 25.7%, Sandbox 18.6%, Procedural Generation 13.2%, Simulation 10.5%

  44. #44 Rela
    70% match1 user reviews100% of 1 reviews2026
    Dev: Relavity
    Windows · Linux

    This program simulates astrophysics, allowing the creation of stellar systems in the void and the experience of being one of the celestial bodies.

    Why similar: Science 42.3%, Education 27.6%, Simulation 16.4%, Sandbox 11.3%, Indie 1.5%

  45. #45 Sandbox:God Simulator
    71% match7 user reviews29% of 7 reviews2023
    Dev: JYS
    Windows

    This is a pixel sandbox game where you can place multiple different elements into the scene to create a unique little world.

    Why similar: God Game 38.9%, Sandbox 25.9%, Simulation 24.5%, Abstract 10.2%, Singleplayer 0.5%

  46. #46 Intelligent Design: An Evolutionary Sandbox
    71% matchMixed45% of 147 reviews2017
    Dev: Pill Bug Interactive
    Windows · Mac · Linux
    Median: 18 minMean: 3.2 hrs≥1hr: 26%

    A toy ecosystem with fully simulated genetics and evolution. Will you tinker with DNA or sit back, relax, and see if life finds a way?

    Why similar: Science 27.8%, God Game 20.2%, Education 19.7%, Sandbox 17.5%, Abstract 7%

  47. #47 Stardust Sandbox
    68% match1 user reviews100% of 1 reviews2026
    Dev: Starciad
    Windows · Linux

    A creative sandbox simulation where you experiment with physical interactions, build structures, and observe emergent behaviors in a world fully under your control.

    Why similar: Science 27.5%, God Game 20.9%, Education 17.6%, Sandbox 16.3%, Simulation 9.5%

  48. #48 The Bibites: Digital Life
    67% matchVery Positive97% of 213 reviews2025
    Dev: Omnia Studios
    Windows · Mac · Linux

    Explore real digital life in The Bibites! Play god by guiding your bibites on their evolutionary journey or engineer your own. Analyze their Neural Network brains and genetic information as they adapt to their environments. Save your favorites and test their strength in Challenge Mode!

    Why similar: Science 33%, Education 20.9%, Sandbox 19.7%, Simulation 11.4%, Procedural Generation 10.8%

  49. #49 Momentum Mayhem
    70% matchNo user reviews2024
    Dev: UnscriptedLogic
    Windows

    A casual 2.5D physics oriented game about building unorthodox contraptions to solve puzzles with a variety of items at disposal

    Why similar: Science 38.5%, Education 24.9%, Sandbox 23.7%, Simulation 8.7%, Casual 4.1%

  50. #50 Legendary mobile phone store simulator
    68% match3 user reviews100% of 3 reviews2025
    Dev: Gold Treasure
    Windows

    Start your own local game store. Fix your phone, or hack them. Set your own prices, expand your stores, and open the secret room that has been sealed for a long time.Unravel the secrets left by Xiao Wang.

    Why similar: God Game 33.2%, Simulation 23.4%, Sandbox 22%, Education 12.2%, Casual 7.6%

  51. #51 Osy Osmosis
    70% match4 user reviews75% of 4 reviews2017
    Dev: Cogent Education
    Windows · Mac · Linux

    Osy Osmosis is a fun game for all ages where you must help Osy stay safe as she navigates through her world collecting stars. To help Osy, you will use osmosis to keep her in balance with the world around her.

    Why similar: Science 52.4%, Education 32.6%, Simulation 9.8%, Casual 3.8%, Indie 1.4%

  52. #52 Futuclass Education
    69% matchPositive80% of 10 reviews2021
    Dev: Futuclass
    Windows

    ** 10 Chemistry and 1 Physics VR Modules – Available for $7.99 Each! ** Learn STEM through gamified experiences in VR! Co-created with award-winning science teachers, tested with students in classroom and at home.

    Why similar: Science 34.9%, Education 22.9%, Sandbox 21%, Simulation 14.7%, Casual 4.2%

  53. #53 Sheep Island
    69% match2 user reviews100% of 2 reviews2020
    Dev: Arkhamsoft
    Windows

    You've get a no people island. Then there is only one thing to do. Use your hands to increase the number of sheep.

    Why similar: God Game 40.6%, Sandbox 29.9%, Simulation 26.2%, 2D 2.7%, Singleplayer 0.6%

  54. #54 Idol Hands
    69% matchMixed44% of 188 reviews2015
    Dev: Pocket GamesPub: Green Man Gaming Publishing
    Windows · Mac · Linux
    Median: 3.3 hrsMean: 4.1 hrs≥1hr: 97%

    Idol Hands is a strategy game where you gradually take over the world by guiding your people and defeating other gods.

    Why similar: God Game 41.6%, Sandbox 29.1%, Simulation 22.8%, Casual 5%, Indie 1.4%

  55. #55 VERDURE
    67% matchNo user reviews2025
    Dev: LXP
    Windows

    Shape nature your way in a surreal playground of infinite plants and trees. Tweak their recipes, prune or let them flourish, and save your best creations into an ever growing collection.

    Why similar: Sandbox 37.8%, Simulation 27%, Procedural Generation 23.2%, Casual 7.6%, 2D 1.9%

  56. #56 Equilibrium
    68% match2 user reviews0% of 2 reviews2021
    Dev: Ayrshire Interactive
    Windows

    Equilibrium combines god-game, resource management, and planetary simulation. Minimise atmospheric pollutants, and keep global temperatures hospitable for human life. Or let dirty industry run rampant and produce a blazing hot tomb world. We're not your boss, it's up to you.

    Why similar: God Game 27.5%, Education 25.3%, Simulation 19.9%, Sandbox 18.7%, Procedural Generation 6.4%

  57. #57 Nature & Life - Drunk On Nectar
    65% matchVery Positive88% of 277 reviews2025
    Dev: Venugopalan Sreedharan
    Windows · Linux
    Median: 3.1 hrsMean: 3.8 hrs≥1hr: 81%

    Play as Animals, Live in Nature! Multiple game modes include Realistic Lifecycles, Survival, Sandbox, Fantasy and Exploration. Unique gameplay for each species! Currently featuring Monarch Butterfly, Praying Mantis, Jumping Spider and other iconic creatures. Mammals, Birds, Reptiles coming soon!

    Why similar: Science 26.4%, God Game 19.5%, Education 15.9%, Sandbox 15.2%, Procedural Generation 12%

  58. #58 MiTOSSis
    66% matchNo user reviews
    Dev: Allen Institute
    Windows

    A biology puzzle with real microscopy data

    Why similar: Science 60.4%, Education 32.3%, Casual 6.5%, Singleplayer 0.8%

  59. #59 Proto-GO-a
    67% matchNo user reviews2025
    Dev: Allen B. Moore
    Windows · Mac

    Enter the world of tiny, virtual protozoa. Take control of one in free play to just explore or attempt to outlast another in a variety of custom boards. The controls are simple, but in the spirit of experimentation you'll have to figure them out on your own by playing...

    Why similar: Science 36.2%, Simulation 20.7%, Sandbox 19.3%, Abstract 9.8%, Casual 8%

PHYSARUM: Slime Mold Simulator cover art

Games Like PHYSARUM: Slime Mold Simulator

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