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Games Like The Last Leukocyte: Immune Protocol

60+ similar titles based on shared tags and player behavior. Themes include Action, Action Roguelike, Bullet Hell, Arena Shooter.

The Last Leukocyte: Immune Protocol header art

Fight cancer as the last leukocyte in a survivors-like action roguelite. Build your loadout with manual and automatic weapons, perks, and items while surviving in a living ecosystem that reacts to your presence and feeds on the remains of the dead.

Reviews: No user reviews — 50%
Released: Coming soon
Developer: Ballpoint Studios
Genres: Action, Casual, Indie, Simulation, Early Access
Platforms: Windows

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  1. #1 Slime Corp
    97% matchMixed64% of 28 reviews2022
    Dev: Fifth Edge Studios
    Windows

    A minimalist top down shooter with slimes.

    Why similar: Looter Shooter 17.6% ★, Arena Shooter 16%, Action Roguelike 10.7%, Bullet Hell 10.4%, Top-Down Shooter 10%

  2. #2 Cubint
    96% match2 user reviews100% of 2 reviews2024
    Dev: UmadYsot
    Windows

    Cubint is a shooter roguelite where you go against a horde of enemies. Use Ally Shooting Turrets to your advantage. Upgrade different Buffs and unlock various Synergies to get stronger. Get powerful Spells that enable tons of new builds.

    Why similar: Arena Shooter 22%, Action Roguelike 15%, Top-Down Shooter 13.7%, Bullet Hell 13.7%, Perma Death 9.8%

  3. #3 Riot Ride
    96% match5 user reviews100% of 5 reviews2024
    Dev: Suronix
    Windows

    Riot Ride is a car-combat roguelike where you play as a car in retro and Tron-like vibes. Speed, drift, and pull off the craziest maneuvers while crushing challenging enemies and bosses with endless synergies of weapons and items.

    Why similar: Looter Shooter 17.5% ★, Bullet Hell 12.3%, Action Roguelike 12.2%, Top-Down Shooter 11.3%, Arena Shooter 11.1%

  4. #4 School Fighter
    95% match3 user reviews100% of 3 reviews2025
    Dev: Sheep Games Studio
    Windows

    School Fighter is a top-down arena roguelite shooter where you play as a student who fights off school enemies using paper airplanes. You have access to a school shop, unique perks, and an upgrade station to help you create a powerful character and overcome the school nightmare!

    Why similar: Arena Shooter 17.6%, Bullet Hell 15.1%, Action Roguelike 14.6%, Roguelite 11.4%, Top-Down Shooter 10.1%

  5. #5 Deflect Boy
    94% matchMostly Positive79% of 19 reviews2024
    Dev: Reima Project
    Windows

    Deflect Boy is a top-down arena shooter, that instead of guns, you only have a shield. Deflect the bullets and combine new skills to create unique deflection powers and survive until the nightmare ends.

    Why similar: Bullet Hell 19.4%, Top-Down Shooter 16.9%, Arena Shooter 16.7%, Action Roguelike 15.8%, Action 8.6%

  6. #6 Looter Survivors
    94% match1 user reviews100% of 1 reviews2026
    Dev: iida-lab
    Windows · Mac · Linux

    Looter Survivors blends survivors-like combat with hack-and-slash loot. Build around randomized gear effects, summon a massive army beside your hero, and fight horde against horde in a compact roguelite designed to be cleared in about 10 hours by focused players.

    Why similar: Looter Shooter 27.7% ★, Action Roguelike 16.4%, Bullet Hell 13.7%, Top-Down Shooter 13.5%, Roguelite 8%

  7. #7 Cards and Guns
    93% matchPositive96% of 24 reviews2024
    Dev: Family Devs
    Windows

    Cards and Guns is a top-down arena shooter roguelite, where you’ll have to defeat hordes of creatures. Choose from a variety of cards and upgrades to create unique builds and survive to the end.

    Why similar: Arena Shooter 21.9%, Top-Down Shooter 15%, Bullet Hell 14.3%, Action Roguelike 13.9%, Perma Death 12.5%

  8. #8 Carnage Cuisine
    92% matchMixed68% of 22 reviews2024
    Dev: MountQ Studios
    Windows

    You are a banana with a gun! Blast your way through hordes of evil cooks and machines in this survivors-like, action rogue-lite. Collect loot, unlock powerful skills, rally your food allies, and lead them to victory! If you fail, upgrade your character and skills, and rise stronger for the next run!

    Why similar: Arena Shooter 26.7%, Action Roguelike 17.3%, Bullet Hell 17%, Top-Down Shooter 15.1%, Roguelite 12.9%

  9. #9 Frontline Frenzy
    91% match2 user reviews33% of 3 reviews2026
    Dev: Frostyy
    Windows

    Frontline Frenzy is a fast-paced top-down WW2 roguelite arena shooter where you fight endlessly growing hordes of enemy soldiers in wave-based arenas. Pick your class, level your character and survive the frontline as the battlefield turns into pure chaos.

    Why similar: Arena Shooter 24.3%, Action Roguelike 16.8%, Top-Down Shooter 16.3%, Bullet Hell 14.2%, Roguelite 10.6%

  10. #10 Elemental Survivors : Roguelike
    90% matchNo user reviews
    Dev: Antonio FilipePub: Afil Games
    Windows

    Fight off hordes of enemies, slay Bosses, choose from a variety of upgrades and combine your spells to create unique and game-breaking builds In this auto-attacking roguelite.

    Why similar: Arena Shooter 19%, Top-Down Shooter 15.7%, Bullet Hell 15%, Action Roguelike 14.2%, Perma Death 10.5%

  11. #11 Stickman's Arena
    91% matchPositive80% of 15 reviews2022
    Dev: Afil Games
    Windows

    Stickman's Arena is a top-down arena shooter roguelite where you play a stickman wielding up to 6 weapons at a time to fight off hordes of enemies. Choose from a variety of upgrades and combine your weapons to create unique and game-breaking builds.

    Why similar: Arena Shooter 19.1%, Top-Down Shooter 15.8%, Bullet Hell 15%, Action Roguelike 14.2%, Perma Death 11.2%

  12. #12 Super Infection Massive Pathology
    89% matchPositive89% of 19 reviews2025
    Dev: Criminal Makers
    Windows

    Guide a brave bacteria to rescue his fiancée Zoe from the creatures of the immune system, using an arsenal of organic weapons and unique abilities.

    Why similar: Arena Shooter 21.7%, Top-Down Shooter 14.7%, Bullet Hell 14%, Action Roguelike 13.9%, Roguelite 10%

  13. #13 Raging Bullet
    88% matchNo user reviews
    Dev: Wicked Spice
    Windows

    Raging Bullet is a mindless, roguelite arena shooter. Unlock tons of upgrades, collect power-ups and survive as you battle hordes of monsters. Make yourself the embodiment of destruction in any way you can.

    Why similar: Looter Shooter 16.7% ★, Arena Shooter 14.4%, Top-Down Shooter 10.3%, Bullet Hell 9.6%, Action Roguelike 8%

  14. #14 Mighty Mage
    89% matchMixed46% of 26 reviews2023
    Dev: Afil Games
    Windows

    Mighty Mage is a top-down arena shooter rogue-lite where you play a cute mage wielding up to 5 elemental spells at a time to fight off hordes of enemies. Choose from a variety of upgrades and spells to create unique builds.

    Why similar: Arena Shooter 18.7%, Top-Down Shooter 16.2%, Bullet Hell 15.4%, Action Roguelike 14.6%, Roguelite 10.8%

  15. #15 Bug Drop
    87% matchNo user reviews2026
    Dev: These Are Serious Games
    Windows

    Fight, upgrade, and survive in a fast-paced top-down action roguelite where 20 unique heroes with special traits, weapons and abilities take on the swarm of alien bugs.

    Why similar: Looter Shooter 21.3% ★, Arena Shooter 18.8%, Top-Down Shooter 12.6%, Action Roguelike 12%, Bullet Hell 12%

  16. #16 Vault of Eras
    86% matchNo user reviews
    Dev: Singulith
    Windows · Linux

    A bullet hell shooter, dungeon crawler about robbing a pyramid that rearranges itself after every run.

    Why similar: Arena Shooter 20.9%, Looter Shooter 19.1% ★, Action Roguelike 16.6%, Top-Down Shooter 16%, Bullet Hell 15.9%

  17. #17 Wreckums
    86% matchNo user reviews
    Dev: Whimstead LLC
    Windows

    You're a tiny one-eyed space creature. Humanity wants you contained. Dodge volleys, smash human spacecraft with banked Wreckballs, and eat their wreckage to heal and mutate. Build a hungry little menace in this neon bullet-hell action roguelite.

    Why similar: Arena Shooter 26.2%, Action Roguelike 18.2%, Top-Down Shooter 16.4%, Bullet Hell 16.3%, Roguelite 11.3%

  18. #18 Bullet Chess
    85% matchNo user reviews
    Dev: The Zoo
    Windows

    A new twist on an age-old game, Bullet Chess is a top-down roguelike shooter where all of the enemies move and attack like chess pieces. Your weapons are also inspired by chess pieces, so everything is intuitive and easy to pick up. Beware though, it gets very hectic very quickly!

    Why similar: Looter Shooter 21.5% ★, Arena Shooter 21.4%, Bullet Hell 14.7%, Action Roguelike 12.8%, Roguelite 9.5%

  19. #19 Goldmourne
    84% matchNo user reviews2026
    Windows

    A roguelike wave survival game where greed is your greatest weapon—and your deadliest risk. Fight as 8 unique heroes, upgrade weapons infinitely, and choose from 30 perks with powerful benefits and painful drawbacks. How far will your greed take you?

    Why similar: Arena Shooter 26.2%, Action Roguelike 17.8%, Top-Down Shooter 16.4%, Bullet Hell 16.3%, Roguelite 11.1%

  20. #20 King Krieg
    84% matchMostly Positive71% of 31 reviews2023
    Dev: SUPERita
    Windows

    Combine abilites to create infinite possibilities of spells and decimate thousands of enemies. King Krieg is a top-down arena roguelite where YOU are the KING and you buy mystical items, find powerful guns, and craft new spells

    Why similar: Arena Shooter 24.7%, Bullet Hell 12.8%, Action Roguelike 12.4%, Top-Down Shooter 10.7%, Shooter 8.9%

  21. #21 Voids Vigil
    82% matchVery Positive94% of 384 reviews2025
    Dev: caiysPub: caiysware
    Windows
    Median: 3.6 hrsMean: 7.8 hrs≥1hr: 70%

    Blast through robotic hordes in this arena auto-battler rogue-lite Brotato-like. Use auto-firing weapons and drones, timely dashes and special abilities to reach the Void where a final Conservator awaits convergence. Spend your Cogs wisely within the varied shops to create unique builds!

    Why similar: Arena Shooter 20.8%, Bullet Hell 14.1%, Action Roguelike 14%, Top-Down Shooter 12.7%, Roguelite 10.9%

  22. #22 Gunclone Arena
    82% matchPositive100% of 17 reviews2026
    Dev: Off North Games
    Windows · Linux

    Gunclone Arena is a fast-paced, top-down looter-shooter roguelite. It's the year 2250, and you are the star of the highest-rated bloodsport live stream! Mow down enemies with chaotic bullet physics, hoard Cash to build your loadout, and win over the crowd to earn Likes for permanent upgrades.

    Why similar: Action Roguelike 18.7%, Bullet Hell 16.8%, Top-Down Shooter 13.7%, Roguelite 12%, Arena Shooter 11.8%

  23. #23 Donut Die
    83% matchNo user reviews2026
    Dev: Five Rooms
    Windows

    Unleash violent magic in Donut Die, a top-down auto-shooter Roguelike. Wield multiple staves, synergize runes, and blast through hordes of enemies to crush the Evil Dessert Corp's conspiracy. The donuts must die!

    Why similar: Arena Shooter 23.5%, Top-Down Shooter 17.9%, Action Roguelike 17%, Bullet Hell 13.7%, Roguelite 11.5%

  24. #24 Frogmancer
    81% matchNo user reviews
    Dev: guizera
    Windows

    A survivors-like shooter where you play as a frog wizard defending your home from swarms of flying enemies. Aim, shoot, level up, and shape your build through a variety of overpowered magical attack patterns!

    Why similar: Arena Shooter 22.8%, Bullet Hell 16.3%, Action Roguelike 16.2%, Top-Down Shooter 13.7%, Roguelite 12.7%

  25. #25 Sweet Skullvivors
    81% matchNo user reviews
    Dev: Jorge T. Vargas
    Windows

    Unleash the power of Mexican food to survive the hordes of hungry Alebrijes. Make the most colorful and delicious Ofrenda the world has ever seen.

    Why similar: Arena Shooter 21.8%, Bullet Hell 15.2%, Action Roguelike 14.4%, Top-Down Shooter 14.4%, Inventory Management 12.6%

  26. #26 Just Shoot
    80% matchNo user reviews
    Dev: Ernandes DiasPub: Texcine Games
    Windows

    Fight through hordes of enemies in this action roguelite, find random weapons and discover secret card combos to create devastating builds and survive the chaos.

    Why similar: Arena Shooter 26%, Bullet Hell 16.9%, Action Roguelike 16.8%, Roguelite 13.3%, Shooter 8.1%

  27. #27 Saucers
    79% matchNo user reviews
    Dev: Elwha Games
    Windows · Mac · Linux

    Saucers is a rogue-lite top-down twin-stick arena style shooter featuring extensive weaponry and upgrade paths so that every run is unique. The further you get, the more weaponry you can stack up to devastating effect. THIS GAME REQUIRES A TWIN STICK GAME CONTROLLER TO PLAY.

    Why similar: Arena Shooter 19.7%, Top-Down Shooter 14.4%, Bullet Hell 13.8%, Action Roguelike 13.4%, Class-Based 12.8%

  28. #28 Chain of Command
    78% matchNo user reviews2026
    Dev: Blinkstrike
    Windows

    Chain of Command is a top-down arena shooter roguelike, where you control a snake-like chain of fighters that attack automatically. Choose your Commander and build your party to create high-synergy builds to crush the invading demon armies.

    Why similar: Arena Shooter 19%, Bullet Hell 16.7%, Action Roguelike 16.5%, Top-Down Shooter 10.4%, Class-Based 9.7%

  29. #29 Chamberflame
    79% match2 user reviews100% of 2 reviews2024
    Dev: Jira Games
    Windows

    Chamberflame is an permadeath roguelike synergy shooter. Wake up with no memory, only to discover there is no easy escape. The only clue is a gateway that teleports you across monster infested lands.

    Why similar: Action Roguelike 16.1%, Perma Death 16.1%, Looter Shooter 14.5% ★, Bullet Hell 9.4%, Arcade 9.3%

  30. #30 Bot Survivors
    77% matchNo user reviews2026
    Dev: SEYSA GAMES
    Windows

    Bot Survivors is a fast-paced action roguelite where you fight off relentless waves of killer robots. Choose your upgrades, build devastating synergies, and survive the mechanical apocalypse!

    Why similar: Arena Shooter 22.3%, Action Roguelike 14.8%, Bullet Hell 14.3%, Top-Down Shooter 14%, Perma Death 11.7%

  31. #31 God Of Weapons
    76% matchVery Positive84% of 5,254 reviews2023
    Dev: Imagine Games
    Windows
    Median: 5.6 hrsMean: 14.4 hrs≥1hr: 86%

    Embark on a thrilling journey in God of Weapons, an action roguelike where you must ascend the tower of Zhor to reclaim the last light for the world. To survive the monster onslaught on each tower's level, you'll need to obtain and carefully organize weapons and accessories in your inventory.

    Why similar: Arena Shooter 20.7%, Action Roguelike 14.3%, Inventory Management 13.9%, Bullet Hell 13.9%, Roguelite 11.9%

  32. #32 NEON STORM
    77% matchNo user reviews2026
    Dev: QuackByte Studio
    Windows

    NEON STORM is a fast-paced top-down Roguelite bullet hell shooter. Pilot your fighter, auto-fire through waves of enemies, dodge deadly attacks, and build powerful upgrades. Survive each run, unlock permanent upgrades, defeat bosses, and chase your highest score!

    Why similar: Arena Shooter 23.1%, Action Roguelike 18%, Bullet Hell 16.4%, Top-Down Shooter 15.4%, Shooter 9.9%

  33. #33 Glorp
    76% matchNo user reviews
    Dev: Raster.Software
    Windows

    Shoot your way through an endless stream of enemies! GLORP is an action roguelike where you must upgrade your skills and weapons to become overpowered

    Why similar: Arena Shooter 22.4%, Action Roguelike 14.9%, Bullet Hell 14%, Perma Death 12.9%, Roguelite 12.2%

  34. #34 Predictile
    78% matchNo user reviews2024
    Dev: AbstrCAT
    Windows

    Predictile" is a unique twin-stick shooting game where the trajectory of enemy attacks is displayed. Overcome waves of randomly placed enemies using skill and the power of prediction lines.

    Why similar: Arena Shooter 28.8%, Action Roguelike 15.6%, Bullet Hell 14.6%, Top-Down Shooter 14.4%, Perma Death 10.9%

  35. #35 Pirate Escape
    75% matchNo user reviews
    Dev: JayFiArts
    Windows

    Pirate Escape is a top-down arena shooter roguelite where you are the captain of you own pirate ship as you raid merchant ships and fight against the navy. Choose from a variety of crew members and items to create unique builds and survive until you reach Tortuga.

    Why similar: Arena Shooter 26.6%, Action Roguelike 18.6%, Top-Down Shooter 16.5%, Roguelite 11.4%, Hack and Slash 8.9%

  36. #36 Comet Force
    74% match2 user reviews100% of 2 reviews2025
    Dev: Radiant Sloth
    Windows · Linux

    Comet Force is a Space Arena Shooter Action Roguelite. Build your camp, recruit to compose and grow your troop, collect upgrades and unique effects, fight enemies and bosses, and choose how the threat evolves. Keep your troop strong enough to survive all waves and close off the anomaly.

    Why similar: Arena Shooter 21.8%, Top-Down Shooter 15.1%, Action Roguelike 14.1%, Bullet Hell 13.6%, Perma Death 12%

  37. #37 NightMare King
    72% matchVery Positive87% of 82 reviews2025
    Dev: Starmoon Cat
    Windows

    Dive into a nightmare-ridden world in this fast-paced roguelite! Choose from 42 characters, 84 weapons, and 176 items to forge your own build. Battle through 8 maps, slay hordes of monsters, level up, collect gold, and upgrade. Can you survive the endless nightmare?

    Why similar: Looter Shooter 28.5% ★, Arena Shooter 23.2%, Bullet Hell 11.5%, Action Roguelike 10.3%, Roguelite 9.6%

  38. #38 Rogue Survivors
    74% match2 user reviews67% of 2 reviews2024
    Dev: Kiro Games
    Windows

    Rogue Survivor is a casual top-down shooter game where you try to survive as long as enemy waves finishes. Choose different heroes and different skills to make better builds.

    Why similar: Arena Shooter 24.3%, Bullet Hell 15.9%, Action Roguelike 15.3%, Roguelite 11.9%, Hack and Slash 8.3%

  39. #39 POOBO
    73% matchPositive85% of 20 reviews2025
    Dev: Merlot Games
    Windows · Mac

    A fast-paced action roguelike where you play as a tiny and adorable poop fighting off bacteria. Upgrade your weapons and items to escape the toilet and claim victory!

    Why similar: Arena Shooter 21.5%, Bullet Hell 15.5%, Action Roguelike 14.6%, Top-Down Shooter 12.1%, Roguelite 11%

  40. #40 Tiny Survivors
    73% matchMixed59% of 349 reviews2023
    Dev: Terry Brash
    Windows

    Tiny Survivors is a chill top-down autobattler with lots of enemies and randomly generated synergies.

    Why similar: Bullet Hell 18.3%, Action Roguelike 17.5%, Roguelite 13.4%, Arena Shooter 10.8%, Hack and Slash 9.5%

  41. #41 Cyber Sentinel: Bullet Hell Breach
    73% matchNo user reviews2025
    Dev: Martin Edmaier
    Windows

    A minimalist top-down bullet hell. Weave through dense patterns, unlock new abilities, and craft busted upgrade combos to survive ever faster waves

    Why similar: Looter Shooter 19.5% ★, Arena Shooter 17.1%, Top-Down Shooter 11.4%, Action Roguelike 10.7%, Bullet Hell 10.3%

  42. #42 Let's KILL This GUY with HAMMERS!!!
    72% matchPositive100% of 11 reviews2024
    Dev: Hammersuck Studios
    Windows

    You heard the title right! This is my life story- an arena game where you kill GUYS with HAMEMRS. It's as shrimple as that! Freaking GET TO IT! My wife is dead. Avenger her.

    Why similar: Arena Shooter 17.9%, Top-Down Shooter 12.3%, Action Roguelike 11.4%, Bullet Hell 11.3%, Perma Death 10.4%

  43. #43 Chaotic World
    70% matchNo user reviews100% of 1 reviews2026
    Dev: technologicalpixel
    Windows

    Chaotic World is a top-down PvE arena shooter where your objective is to clear waves of different and unique enemies until you destroy them all. Set across colorful maps, you will have the opportunity to make yourself stronger by leveling up and finding loot on your way to the last wave!

    Why similar: Arena Shooter 31.3%, Looter Shooter 27.4% ★, Top-Down Shooter 19.6%, Shooter 8.2%, Arcade 6.6%

  44. #44 Guns and Donuts
    71% matchNo user reviews
    Dev: TubbyYoungbrosPub: TubbyGames
    Windows

    Donuts! and Guns!? Choose from a host of Donut! characters (each with multiple unique Guns!) and traverse wonderfully large locations in search for more Donut! companions. Fight through hordes of miscellaneous enemies by using either your Guns!, your Donuts!, or your puzzle solving skills!

    Why similar: Arena Shooter 22.9%, Bullet Hell 14.7%, Top-Down Shooter 14.2%, Roguelite 11.2%, Arcade 9.5%

  45. #45 Robot Arena Survivors
    70% matchPositive90% of 49 reviews2024
    Dev: ShidyGames
    Windows

    Robot Arena Survivors is a single-player arena auto-shooter where you're fighting against waves of hostile robots using a powerful arsenal made of hover tank units. Customize your own set of abilities and dismantle your enemies to claim your fame into the leaderboards.

    Why similar: Arena Shooter 16.4%, Bullet Hell 16.2%, Action Roguelike 15.5%, Top-Down Shooter 15%, Roguelite 13.2%

  46. #46 Mighty X Arms
    69% match2 user reviews100% of 2 reviews2026
    Dev: Stale Boi
    Windows

    Mighty X Arms is a roguelike survivor inspired by Brotato, featuring collectible weapon-creatures called Arms. Build your loadout, upgrade them, and mow down enemy swarms to survive.

    Why similar: Arena Shooter 22.5%, Top-Down Shooter 15.1%, Action Roguelike 14.6%, Bullet Hell 13.7%, Roguelite 10.3%

  47. #47 Shoot & Sow
    71% match8 user reviews100% of 8 reviews2024
    Dev: Taskaev Iurii
    Windows

    Shoot & Sow is a top-down arena shooter roguelite, where players control unique characters and fight vegetables and fruits. Players can plant seeds to grow special items, as well as buy a variety of weapons and items. Complete the talent tree to gain more power. Can you survive on your own farm?

    Why similar: Arena Shooter 22.3%, Bullet Hell 17.8%, Top-Down Shooter 17.4%, Action Roguelike 16.9%, Roguelite 12.2%

  48. #48 X-Mutation
    70% matchVery Positive85% of 53 reviews2024
    Dev: ProjectX
    Windows

    Survive thousands of monsters in X-Mutation, a hardcore 3D top-down rogue-lite action game. Mutate your body into diverse weapons, choose from hundreds of mutations, and uniquely upgrade to craft your personal combat style!

    Why similar: Arena Shooter 19.5%, Action Roguelike 14.6%, Bullet Hell 14.3%, Top-Down Shooter 13.7%, Roguelite 11.8%

  49. #49 2 Many Pixels
    71% match2 user reviews50% of 2 reviews2022
    Dev: Alex Le Mesurier
    Windows

    2 Many Pixels is an endless & fast-paced 2D minimal shooter. Blast enemies & unlock upgrades to help you survive for as long as possible!

    Why similar: Arena Shooter 26%, Top-Down Shooter 15.9%, Bullet Hell 15.3%, Perma Death 12.8%, Roguelite 11.2%

  50. #50 07GORILLAS
    67% matchPositive93% of 41 reviews2026
    Dev: Highway404
    Windows

    07 GORILLAS is an arena kung fu shooter Game where players control a squad that automatically eliminates nearby enemies. Choose different gorilla units and unlock gorillas resonance bonuses and create unique builds, Lead your gorillas and wreak havoc in the enemy tide.

    Why similar: Arena Shooter 26.4%, Bullet Hell 18.1%, Top-Down Shooter 14.7%, Shooter 9.5%, Action Roguelike 9.5%

  51. #51 Too Many CUBES!
    69% matchNo user reviews
    Dev: Jacob BattsPub: Stand Gaming
    Windows

    Shatter overwhelming cube swarms in a fast arena-survival roguelite. Aim your evolving arsenal, conquer five hazardous zones, destroy their Guardians, and climb five Fracture difficulty tiers—solo or in two-player local co-op.

    Why similar: Arena Shooter 21%, Action Roguelike 13.3%, Bullet Hell 12.8%, Top-Down Shooter 11.7%, Roguelite 9.3%

  52. #52 Hamdy: a Roguelike Farm Mayhem
    68% matchNo user reviews
    Dev: POFU Games
    Windows

    The farm is under attack! Fight against an alien invasion as Hamdy, an armed scarecrow. In this top-down arena roguelike, build your loadout with up to 6 weapons, grow stronger after each wave, and survive until the very end.

    Why similar: Arena Shooter 20.6%, Bullet Hell 17.4%, Action Roguelike 16.6%, Roguelite 10.6%, Top-Down Shooter 10.2%

  53. #53 Broken Scary Skeleton
    68% matchNo user reviews
    Dev: GDAEON
    Windows

    Broken Scary Skeleton is a rogue-like top-down shooter in which you are cursed with love. Fight and possess defeated enemies to change your character's abilities and use different types of weapons.

    Why similar: Arena Shooter 22.4%, Bullet Hell 14.5%, Top-Down Shooter 13.7%, Action Roguelike 11.1%, Roguelite 10.7%

  54. #54 PlatinumS
    69% match2 user reviews50% of 2 reviews2024
    Dev: lucemCD
    Windows

    PlatinumS is a roguelite top-down arena shooter that brings the ultimate hero's party-building experience to life, empowering heroes to conquer dungeons. Players have the option to select from a range of items and buffs to craft their own distinctive builds.

    Why similar: Arena Shooter 21.2%, Action Roguelike 13.5%, Bullet Hell 13.4%, Top-Down Shooter 11.9%, Roguelite 10.2%

  55. #55 Dreadlight
    68% matchNo user reviews
    Dev: Odd Lantern Games
    Windows

    Hold back the dark in a horror arena-survival roguelite. Fight inside your lantern's glow, build a six-weapon arsenal, and brave cursed relics. Rising Dread tears scars into the arena that persist between waves. Spend scrap to seal them, or save it for your next upgrade.

    Why similar: Arena Shooter 24.9%, Action Roguelike 19.9%, Bullet Hell 19%, Top-Down Shooter 16.4%, Roguelite 14.3%

  56. #56 Rip & Tear
    67% matchMostly Positive70% of 10 reviews2025
    Dev: CJPub: Outofthematrix
    Windows

    Rip &Tear is a brutal top-down 2D arcade shooter where your shotgun is your only lifeline. Face endless waves of demons, cultists, and biomechanical horrors in a blood-soaked battle for survival. No gimmicks—just pure, relentless carnage.

    Why similar: Looter Shooter 16.9% ★, Arena Shooter 14.8%, Perma Death 12.7%, Action Roguelike 9.8%, Arcade 8.6%

  57. #57 Killdozer
    66% match7 user reviews86% of 7 reviews2026
    Dev: SpliceDev
    Windows · Mac

    Destroy the town! Killdozer is an action roguelike where you fight off a police onslaught while bulldozing towns. Unlock items and upgrades along the way to build your Killdozer into the ultimate destruction machine.

    Why similar: Arena Shooter 22.6%, Bullet Hell 14.7%, Action Roguelike 14.4%, Top-Down Shooter 14.1%, Roguelite 10.4%

  58. #58 Noobs Are Coming
    64% matchVery Positive82% of 1,615 reviews2025
    Dev: Overboy
    Windows
    Median: 3.6 hrsMean: 11.0 hrs≥1hr: 72%

    YOU ARE THE FINAL BOSS. Brutal synergy arena roguelike. Pick your Final Boss character, equip boss patterns and combine tons of attacks to create unique builds. Play solo or in co-op!

    Why similar: Arena Shooter 22.6%, Bullet Hell 14.7%, Action Roguelike 14.6%, Top-Down Shooter 13.6%, Roguelite 12.1%

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Games Like The Last Leukocyte: Immune Protocol

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