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Games Like Aptamirror

60+ similar titles based on shared tags and player behavior. Themes include Singleplayer, Puzzle, Science, Indie.

Aptamirror header art

Aptamirror is a meditative physics-based puzzle game inspired by molecular biology. Manipulate RNA strands by grabbing, mutating, cleaving, and ligating to match increasingly complex target structures. Challenge yourself with 50 handcrafted puzzles designed by a PhD Biochemist. Think. Fold. Repeat.

Reviews: No user reviews — 50%
Released: Q4 2026
Developer: Stellar Genesis Games
Genres: Casual, Indie, Simulation, Strategy
Platforms: Windows

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    97% matchVery Positive90% of 60 reviews2021
    Dev: Vectmatica
    Windows

    Play with lasers and solve puzzles in Laser Attraction. Use reflection, refraction, dispersion and filtration to direct the laser beams, mix and separate colours, open doors, hit targets and complete puzzles.

    Why similar: Science 29.2%, Physics 14.8%, Difficult 14.2%, Puzzle 9.6%, Logic 9.2%

  2. #2 Build Molecules for Vick - Chemistry Puzzle
    96% matchPositive80% of 20 reviews2021
    Dev: Sprovieri Games
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    Build molecules for Vick is a Puzzle game about chemistry. Assemble molecules by snapping and swapping atoms together until you assemble the molecule Vick needs. No prior knowledge of chemistry is required.

    Why similar: Science 23.7%, Abstract 11.5%, Education 10.8%, Logic 9.9%, Difficult 8.9%

  3. #3 Colorgrid
    95% matchVery Positive92% of 155 reviews2019
    Dev: Minimol Games
    Windows · Mac

    Colorgrid is a puzzle game about mixing colors in a Lab. Find the correct positions for your lasers and mirrors to get the right mix of colors in each material.

    Why similar: Science 22.2%, Physics 11.8%, Difficult 11.8%, Logic 10.3%, Education 10.2%

  4. #4 Sokobond
    95% matchVery Positive93% of 694 reviews2014
    Dev: Alan HazeldenPub: Draknek & Friends
    Windows · Mac
    Median: 1.6 hrsMean: 4.2 hrs≥1hr: 57%

    Sokobond is an elegantly designed puzzle game about chemistry. It's logical, minimalist, and beautiful - crafted with love and science.

    Why similar: Science 27.7%, Abstract 14%, Difficult 12.1%, Education 11.7%, Logic 7.5%

  5. #5 Unknot!
    93% matchPositive91% of 33 reviews2025
    Dev: P.F.J.
    Windows · Mac

    Unknot! is a physics-simulation puzzle game where you unknot knots with simple controls, based on knot theory. Blending art, puzzles, and math, it delivers a unique experience—whether you’re a casual player or a hardcore puzzle enthusiast.

    Why similar: Science 27.6%, Abstract 16.1%, Physics 15.5%, Logic 13.3%, Puzzle 8.5%

  6. #6 Function Ball(関数球)
    94% matchNo user reviews2024
    Dev: yachi
    Windows

    You input any function to guide the red ball on the xy-plane to the goal.

    Why similar: Science 21.3%, Education 18%, Physics 16.7%, Abstract 13.7%, Puzzle 11.4%

  7. #7 Orbital Trajectory
    93% matchNo user reviews2026
    Dev: ElastiCat
    Windows

    Plan, launch, and observe in a minimalist physics puzzle game about discovering trajectories through gravity fields and orbital currents.

    Why similar: Science 18.4%, Logic 16.5%, Physics 14%, Abstract 13.8%, Strategy 11.2%

  8. #8 Space Thrusters
    92% matchNo user reviews
    Dev: CrystalDam Studios
    Windows

    Space Thrusters is a physics puzzle game where you plan the perfect route through enemy ship vents. Guide a bomb through tight spaces to trigger satisfying, cinematic explosions! The stakes are high: you must visualize your exit before you enter. Unravel the secrets of space-one detonation at a time

    Why similar: Logic 18%, Physics 15.4%, Difficult 15%, Space 14.4%, Puzzle 11.3%

  9. #9 LX Patterns
    91% matchPositive84% of 31 reviews2021
    Dev: Thedox Games
    Windows · Linux

    How smart are you? The ability to recognize patterns is used to measure intelligence. LX patterns is a puzzle game in which you have to identify different patterns while listening to a relaxing soundtrack.

    Why similar: Education 19.1%, Science 18.8%, Difficult 18.1%, Abstract 12.6%, Puzzle 10.2%

  10. #10 Neutrino
    91% match7 user reviews100% of 7 reviews2022
    Dev: Mario Brandao
    Windows · Mac · Linux

    Neutrino, The Mission - a minimalist game where a photon seeks the core of Neutrinos Kingdom, find out why they have mass and destroy them!

    Why similar: Science 30.2%, Logic 14.8%, Space 13%, Puzzle 8.7%, Abstract 7.9%

  11. #11 Chimp Memory
    89% matchPositive94% of 17 reviews2024
    Dev: Windmill's Light
    Windows

    Chimp Memory is a logical puzzle game and memory challenge. Take on the same tests faced by lab monkeys and prove your memory skills are sharper than theirs. Can you outperform the primates? Test yourself and find out!

    Why similar: Science 41.1%, Education 23.8%, Logic 16.5%, Simulation 6.8%, Casual 5.8%

  12. #12 MarbleFlow
    90% matchNo user reviews2026
    Dev: WayCrest
    Windows

    MarbleFlow is a physics-based puzzle game where you place various devices and rails to guide a marble to its goal. Arrange objects and use their interactions to solve each puzzle. Enjoy calm yet challenging puzzles with the gentle sounds of marbles and mechanisms.

    Why similar: Logic 21.2%, Difficult 20.3%, Physics 20.2%, Puzzle 13.2%, Strategy 9%

  13. #13 OCTOPTICOM
    88% matchVery Positive95% of 56 reviews2018
    Dev: UP DEVELOPMENT LTD.
    Windows · Linux

    OCTOPTICOM is an open-ended puzzle programming game about designing and optimizing optical computing devices. Use lasers, mirrors, filters and other components to read, transform and write sequences of colored squares.

    Why similar: Science 26.3%, Abstract 13.6%, Education 12.6%, Logic 12%, Difficult 11.5%

  14. #14 ColorSweeper
    88% matchNo user reviews
    Dev: ARRKKA
    Windows

    A unique and addictive color puzzle game that combines Minesweeper and Nonogram! Like Minesweeper, the player's goal is to fill in all the blanks with the correct color, using the information given on the 8 adjacent squares.

    Why similar: Education 22.9%, Difficult 19.4%, Abstract 13.4%, Puzzle 13.2%, Logic 10.2%

  15. #15 NBody Gravitation
    87% match4 user reviews100% of 4 reviews2023
    Dev: Sean Frett
    Windows · Linux

    Place asteroids and planets and send them orbiting into targets in a physics-based puzzle game where everything attracts everything.

    Why similar: Science 30.3%, Education 20.6%, Puzzle 11.7%, Space 11.2%, Physics 10.2%

  16. #16 Rela
    86% match1 user reviews100% of 1 reviews2026
    Dev: Relavity
    Windows · Linux

    This program simulates astrophysics, allowing the creation of stellar systems in the void and the experience of being one of the celestial bodies.

    Why similar: Science 35.3%, Education 18.6%, Physics 16.2%, Space 12.8%, Stylized 8.3%

  17. #17 Newton's Fourth Law
    86% matchVery Positive94% of 217 reviews2025
    Dev: Newtonian Studios
    Windows

    Fight against brain-rot in this story-driven educational physics puzzle game. You will need to learn and apply high school physics concepts to solve increasingly challenging problems and uncover a galaxy spanning plot. When you have finished, you will be able to take a college level physics course.

    Why similar: Science 27%, Education 16.2%, Difficult 13.8%, Physics 13.2%, Logic 12.2%

  18. #18 Portal Journey: Portarius
    85% matchPositive81% of 26 reviews2018
    Dev: Dmitry Poznukhov
    Windows · Mac · Linux

    Open a portal and begin your journey! Teleport rocks, water and your spaceship. Immerse in handcrafted colorful worlds, solve puzzles and be the first at the center of the Earth.

    Why similar: Science 29.1%, Physics 11.6%, Difficult 11.2%, Space 10.8%, Puzzle 10.8%

  19. #19 SPACE TOW TRUCK - ISAAC NEWTON's Favorite Puzzle Game
    84% matchPositive95% of 22 reviews2021
    Dev: Eric Laflamme
    Windows

    Control gravity, orbit around black holes, and have fun mastering physics with your car in space! With this educational puzzle game, only your genius and your analytical skills can get you out of trouble after a painful car crash on the Moon!

    Why similar: Science 39.7%, Education 20.6%, Physics 15.2%, Puzzle 11.4%, Space 7%

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    84% match4 user reviews100% of 4 reviews2022
    Dev: Sergey Krasnikov
    Windows

    Ecocoru is a puzzle game where you have to solve compass and ruler construction problems.

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    83% match2 user reviews100% of 2 reviews2024
    Dev: kakeia
    Windows

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    Dev: Milky Fox
    Windows

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    Windows · Mac · Linux

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    81% matchNo user reviews
    Dev: Neutrino Interactive
    Windows

    One Degree Off is a 2D puzzle game that turns laser physics into captivating brain teasers. Master reflection and refraction to guide multiple lasers through intricate levels, Mix and split colors and, Control your beam's intensity to reach your goals.

    Why similar: Science 29%, Physics 17.2%, Puzzle 13.7%, Logic 11.4%, Simulation 9.4%

  25. #25 Ideal Gas
    82% matchNo user reviews2022
    Dev: Rude Fox Games
    Windows

    In this Explosive Ballon Based Puzzler, all you have to do is get the balloons safely to the end zone. Simple, right? Use a variety of fans and other tools to avoid obstacles and finish the experiment.

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  26. #26 TraptionBakery
    80% match8 user reviews100% of 8 reviews2020
    Dev: Jon PrestidgePub: ProperBostin Interactive
    Windows

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    Dev: Dirty Paws Studio
    Windows

    You are an electrician, moving back to your hometown in the Austrian Alps, which you find lacks a certain... spark. Promptly tasked with wiring up the village, you solve electrical puzzles, blow fuses and master real-world circuitry techniques. Electrify the Alps, one circuit at a time.

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    78% matchNo user reviews2026
    Dev: Pentu
    Windows

    Step into Zodiacra - an atmospheric puzzle game with calming stellar visuals. Connect the stars to reveal constellations across a serene night sky, uncovering zodiac signs, mythical creatures, divine beings, and the stories behind them.

    Why similar: Education 24.1%, Abstract 16.1%, Puzzle 13.2%, Logic 10%, Space 8.4%

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    79% matchMixed61% of 130 reviews2017
    Dev: Snkl Studio
    Windows
    Median: 18 minMean: 6.8 hrs≥1hr: 21%

    You are a pilot of the spaceship "Znkl - 177". You need to deliver a capsule with important information to the cargo spaceship.

    Why similar: Difficult 13.6%, Space 13%, Logic 13%, Education 12.4%, Physics 11.9%

  30. #30 PlanetariumVR
    78% match9 user reviews78% of 9 reviews2021
    Dev: hublab
    Windows

    Planetarium for VR to learn about the stars, constellations, and deep sky objects from the Messier, Caldwell, Herschel400, NGC, IC, Sharpless, and Arp catalogs. Learn the positions of stars and the Messier objects; play the minesweeper in VR in a polyhedron.

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  31. #31 That Rocket Game
    77% matchPositive85% of 26 reviews2023
    Dev: Dan's Games
    Windows

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  32. #32 Futuclass Education
    77% matchPositive80% of 10 reviews2021
    Dev: Futuclass
    Windows

    ** 10 Chemistry and 1 Physics VR Modules – Available for $7.99 Each! ** Learn STEM through gamified experiences in VR! Co-created with award-winning science teachers, tested with students in classroom and at home.

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  33. #33 TerraBlocks
    76% match5 user reviews40% of 5 reviews2024
    Dev: shrubec
    Windows · Linux

    TerraBlocks is a geography-based puzzle game where you move and rotate drifting continent pieces from the North Pole to their correct places. As you progress, the challenge increases. Test your spatial awareness and geographic knowledge while rebuilding the world!

    Why similar: Education 23.6%, Science 19.8%, Puzzle 13.2%, Space 11.5%, Physics 9.7%

  34. #34 Senalux
    76% matchPositive97% of 29 reviews2017
    Dev: Pixel with Hat
    Windows · Mac · Linux

    Senalux is a hex-based puzzle game about optics where you solve challenging puzzles with colorful lasers. Use the red, green and blue lasers, combine them to the right color and illuminate the target.

    Why similar: Science 28.1%, Difficult 17.6%, Logic 16.4%, Puzzle 12%, Abstract 6.5%

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    75% matchPositive93% of 14 reviews2022
    Dev: RainForest GamesPub: Ratalaika Games S.L.
    Windows

    Move the blocks strategically, your objective is to change the trajectory of the cannonballs until they reach the pirate ship. Simple yet challenging.

    Why similar: Abstract 22.2%, Strategy 15.2%, Difficult 14.6%, Physics 11.5%, Logic 11.1%

  36. #36 Sokobond Express
    73% matchVery Positive89% of 101 reviews2024
    Dev: José HernándezPub: Draknek & Friends
    Windows · Mac · Linux

    Sokobond Express is a beautifully minimalist puzzle game that combines chemical bonds and puzzling pathfinding in novel ways.

    Why similar: Science 36.8%, Abstract 18.3%, Logic 16.9%, Puzzle 10%, Education 4.1%

  37. #37 Logos Orbit
    74% matchNo user reviews2026
    Dev: IS Product
    Windows

    Logos Orbit is an emergent cosmic tuning simulation where you rewrite the "Logos" of an ever-expanding universe to control the collision and equilibrium of stars. Place gravity-altering Sigils to tune the orbits of star systems on the brink of collapse.

    Why similar: Science 29.2%, Logic 17.1%, Physics 16.6%, Space 15.3%, Puzzle 7.3%

  38. #38 Molecule - a chemical challenge
    75% matchMostly Positive71% of 28 reviews2018
    Dev: a.mighty.dish
    Windows

    Discover molecules and learn about science in this addictive Sokoban-style puzzle game!

    Why similar: Science 44.3%, Education 22.2%, Difficult 18.4%, Puzzle 10.7%, Indie 4.3%

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    74% matchNo user reviews2028
    Dev: Hanoi Studios
    Windows · Mac · Linux

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  40. #40 Reflect
    73% match6 user reviews100% of 7 reviews2024
    Dev: Zebra Games
    Windows

    This is a simple and complex puzzle game about light. You need to use Optical components to direct lights and lit up the rings.

    Why similar: Science 20%, Difficult 19.7%, Physics 14.7%, Puzzle 12.7%, Logic 12.4%

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    73% matchVery Positive99% of 149 reviews2019
    Dev: Bart Bonte
    Windows

    You might think that working on the assembly line is tedious work, but not if you're manufacturing Factory Balls! Your job in this logic puzzle game is to custom craft each ball to a specific order. You've got all the tools you need to fulfill each order... except the instruction manual.

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    71% matchPositive93% of 14 reviews2025
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    Windows · Mac

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    72% matchPositive100% of 12 reviews2023
    Dev: design.reject
    Windows

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  44. #44 Pythagoria
    72% matchMostly Positive75% of 258 reviews2016
    Dev: Vladimir Maslov
    Windows
    Median: 3.1 hrsMean: 215.5 hrs≥1hr: 79%

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  45. #45 AntiMatcher
    71% matchNo user reviews2026
    Dev: GigoMakes
    Windows

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  46. #46 AToM - 1974
    69% match1 user reviews100% of 1 reviews2026
    Dev: TMWFAPub: The Man Who Flew Away
    Windows

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    68% matchPositive83% of 12 reviews2026
    Dev: kazakovstudios
    Windows

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  48. #48 Gearplexed
    71% matchNo user reviews2026
    Dev: Train of Thought Games
    Windows

    Enjoy playing with gears? Gearplexed is a constructive problem-solving game with a variety of gear-based puzzles ranging from opening gates to building factories. Build gears to get the right amount of speed or torque to the target gears and be careful not to lock up your gear train.

    Why similar: Science 31.6%, Education 17.1%, Physics 11.6%, Logic 9.7%, Puzzle 9.1%

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    70% matchPositive100% of 10 reviews2023
    Dev: UP DEVELOPMENT LTD.
    Windows · Linux

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    69% matchPositive100% of 20 reviews2023
    Dev: Fabien Corblin
    Windows · Linux

    COSMIC HOLES is a logic puzzle game based on the 5 elements of Chinese cosmology: Wood, Fire, Earth, Metal, and Water. Solve and maintain the balance of the elements in an environment that adapts to your own energy. Relaxing and explosive!

    Why similar: Difficult 22.3%, Logic 22.1%, Puzzle 13.2%, Space 11.9%, Education 10.3%

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    70% matchMostly Positive75% of 305 reviews2017
    Dev: The Young Socratics
    Windows · Mac
    Median: 1.5 hrsMean: 9.1 hrs≥1hr: 62%

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    67% matchPositive95% of 21 reviews2025
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    Windows · Linux

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    70% matchNo user reviews2026
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    67% matchPositive90% of 10 reviews2025
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    Windows · Mac

    Move the ball, avoid obstacles, earn coins, and reach the destination using only circular orbits! It sounds easy and simple... but it's not! Immerse yourself in a world of deep and challenging puzzles!

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    67% match2 user reviews67% of 3 reviews2025
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    67% match8 user reviews100% of 8 reviews2024
    Dev: JHSSF
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  57. #57 HoloLAB Champions
    69% matchPositive88% of 24 reviews2018
    Dev: Schell Games
    Windows

    Grab your safety goggles and set out on a chemical-burning, liquid-stirring, camera-whirring competition in HoloLAB Champions, a virtual reality chemistry game show.

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    66% matchPositive100% of 12 reviews2024
    Dev: BABYCOCO
    Windows · Mac · Linux

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    68% matchMostly Positive75% of 163 reviews2018
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    Windows
    Median: 48 minMean: 6.1 hrs≥1hr: 40%

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    64% matchPositive100% of 12 reviews2025
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    Axona is a grid-based puzzle game that brings the challenge of 3D cube solving to a 2D plane. Strategically roll your cube, match the correct faces to collect the keys, and unlock glyphs to solve each level.

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Aptamirror cover art

Games Like Aptamirror

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