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Games Like Antidote to despair

60+ similar titles based on shared tags and player behavior. Themes include Medical Sim, Simulation, Singleplayer, 2D.

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  1. #1 Opawration!
    97% matchNo user reviews
    Dev: chinchingames
    Windows

    A 2D, veterinarian horror game. In this game, select the appropriate treatment and treat patients with topical products injections, surgeries. Treat patients over the course of 7 days, using the in-game computer to research the best treatment option.

    Why similar: Medical Sim 56.4% ★, Point & Click 11.2%, Dark 9.6%, Choices Matter 8.9%, Dystopian 5.4%

  2. #2 The Attending
    96% matchNo user reviews
    Dev: Abreu Data Works
    Windows

    You are the attending physician on the night shift. Your doctors work the cases — and report what they believe, not what's true. Read their workups, catch the miss before it walks out the door, and spend your trust where it counts. One night. One board. Everyone's yours.

    Why similar: Medical Sim 61.6% ★, Management 11.1%, Choices Matter 9.4%, Simulation 8.6%, Story Rich 4.7%

  3. #3 Мне только спросить!
    96% matchNo user reviews
    Dev: Каракули
    Windows

    "I just want to ask!" is a medical registrar simulator with time management elements set in a provincial Russian hospital, featuring humorous elements. Your main task is to help patients, but each one has their own story.

    Why similar: Medical Sim 59.5% ★, Management 10%, Point & Click 9.9%, Simulation 7%, Choices Matter 6.8%

  4. #4 Prescribe and Pray
    95% matchMostly Positive74% of 81 reviews2026
    Dev: Nuclear Rabbits
    Windows

    Awaken the incompetent doctor within you! Diagnose strange patients, examine their absurd symptoms… and prescribe treatments that could change their lives… or cut them short. Your actions will have consequences.

    Why similar: Medical Sim 45.5% ★, Detective 15.6%, Choices Matter 11.1%, Management 6.5%, Point & Click 5.9%

  5. #5 Psyhonds
    93% matchMostly Positive70% of 10 reviews2026
    Dev: Meriteri GamesPub: Terrabyte Games
    Windows

    A satirical mental hospital survival simulator: control four unstable characters, craft from junk, forge dubious alliances, communicate with patients and staff, and choose between a quiet life in a ward, a riot, or a risky escape to freedom.

    Why similar: Medical Sim 63.2% ★, Visual Novel 8.1%, Puzzle 7.3%, Simulation 6.6%, Choices Matter 6.3%

  6. #6 Hospital Manager
    94% matchMixed46% of 255 reviews2015
    Dev: CCCPPub: Microids Indie
    Windows · Mac
    Median: 1.1 hrsMean: 9.4 hrs≥1hr: 56%

    Experience something novel, bursting with extraordinary phenomena and strange situations in your hospital! Only you have the power to make the best decisions and to make your hospital the most popular one! But beware: Several events will add some spice to your life! Embark on the career of your life!

    Why similar: Medical Sim 72.3% ★, Management 18.9%, Simulation 8.7%

  7. #7 Necrologium
    92% matchPositive90% of 31 reviews2025
    Dev: Bob's Cult StudioPub: Ovid Works
    Windows · Mac · Linux

    Seven corrupted souls died in one fateful night. Discover their sins and unravel the mystery that surrounds their mortal shells.

    Why similar: Medical Sim 51.8% ★, Detective 16.6%, Visual Novel 7.4%, Dark 6.5%, Atmospheric 5.5%

  8. #8 Sanatorium - A Mental Asylum Simulator
    91% matchMixed61% of 230 reviews2025
    Dev: ZeitglasPub: Shoreline Games
    Windows · Mac

    The year is 1923—step inside Castle Woods Sanatorium, where care and cruelty blur together. Disguised as a doctor, you’ll diagnose and treat patients using a deck of symptoms, tests, and outdated therapies. But tread carefully: one wrong move could expose you as an impostor.

    Why similar: Medical Sim 42.5% ★, Detective 12.8%, Point & Click 8.9%, Choices Matter 7.4%, Dark 6.8%

  9. #9 All Our Broken Parts
    91% matchNo user reviews
    Dev: 锡鸟 Tin BirdPub: GCORES PUBLISHING
    Windows

    Experience a story-driven adventure game as a robot doctor. In a city of robots, illness is looming. Crack open ports and units to trace causes. Diagnose, repair and cross paths with robots and stories. Uncover secrets buried in the past and future, discover the truth that makes each robot unique.

    Why similar: Medical Sim 39% ★, Dystopian 10.2%, Point & Click 8.5%, Choices Matter 8.2%, Visual Novel 6.6%

  10. #10 Epi Derick
    90% matchPositive80% of 10 reviews2025
    Dev: Fireslug Studios
    Windows

    You run the only pharmacy in a rural town. Each face at the counter is the same, each ailment slightly different. Provide Care - Follow Our Rules - Stay Safe.

    Why similar: Medical Sim 59.6% ★, Simulation 10.3%, Management 8.5%, Stylized 8.1%, Resource Management 5.5%

  11. #11 Doctor Dash ASMR Hospital
    89% matchVery Positive88% of 99 reviews2024
    Dev: Friedegggames OUPub: Brightika, Inc.
    Windows

    💊 Your dream hospital awaits! 🏥❤️ Addictive levels and unique locations ✈️ Hours of entertainment in the time-management genre ⏰

    Why similar: Medical Sim 60.8% ★, Point & Click 14.8%, Simulation 10.6%, Management 9.8%, 2D 3.3%

  12. #12 PSY in Apocalypse
    89% matchNo user reviews
    Dev: Quantum Strawberry
    Windows

    PSY in Apocalypse는 사실적인 2D 정신과 어드벤처 게임입니다. 여러분은 게임 속에서 정신과 의사가 되어 환자들을 직접 치료하게 됩니다. 포스트 아포칼립스 세계를 의사의 관점이라는 다소 새로운 시각으로 이야기를 풀어나가게 됩니다.

    Why similar: Medical Sim 67.6% ★, Puzzle 7%, Atmospheric 6.4%, Story Rich 5.8%, Simulation 4.6%

  13. #13 Elixir
    87% matchPositive93% of 44 reviews2024
    Dev: Moxu Projects
    Windows

    Welcome to Elixir, a 2D strategic puzzle experience. Become an ancient alchemist with a mysterious past to unlock. Explore & find lost souls who need your help. Uncover Elixirs and experiment on them, and yourself. Embark on a dark journey to solve puzzles, unlock recipes and unearth hidden secrets.

    Why similar: Medical Sim 53.6% ★, Point & Click 10.1%, Puzzle 7.3%, Dark 6.1%, Stylized 5.8%

  14. #14 Dr Greenstuff
    88% matchVery Positive87% of 149 reviews2018
    Dev: Black DiskettePub: Black Diskette Studio
    Windows

    Discover the life of Dr Greenstuff, grow marijuana, coca, make meth', drugs and more to keep your legal/illegal business running.

    Why similar: Medical Sim 76.5% ★, Simulation 12.7%, Resource Management 6.4%, Indie 4.3%

  15. #15 Pompiers Simulator
    86% match4 user reviews100% of 4 reviews2025
    Dev: Vincent TartarPub: Oasis Video Games
    Windows

    You’re not a firefighter, but you dream of experiencing the intensity of a real emergency rescue operation? Pompiers Simulator puts you at the heart of first aid missions, in the shoes of a responder, within a simulation designed by real firefighters.

    Why similar: Medical Sim 67.8% ★, Point & Click 11.3%, Simulation 7.6%, Choices Matter 7.1%, Pixel Graphics 3.7%

  16. #16 Underdose
    86% matchNo user reviews
    Dev: Big Cheese Studio
    Windows

    In a not-too-distant, retro-future world shaken by a shortage of medicine, a talented pharmacist is accused of murdering Patient Zero. He flees to the slums, where he tries to survive in isolation until he can recreate the formula for the drug that will save his life.

    Why similar: Medical Sim 43.2% ★, Dystopian 12.2%, Point & Click 11%, Choices Matter 7.3%, Management 6.7%

  17. #17 Dilemma
    84% matchPositive95% of 22 reviews2026
    Dev: DrAxelStudio
    Windows

    You don't cure patients; you decide their fate. In this grim medical sim, review records and face impossible bioethical dilemmas. Consult the Medical Bible and choose who gets the bed. Every signature impacts your Ethics, Reputation, and Legal Risk. In a broken system, mercy is a dangerous luxury.

    Why similar: Medical Sim 50.8% ★, Dark 8.7%, Visual Novel 7.8%, Simulation 7.2%, Management 6.7%

  18. #18 Heart's Medicine - Hospital Heat
    84% matchVery Positive96% of 366 reviews2017
    Dev: Blue GiraffePub: GameHouse
    Windows · Mac
    Median: 5.1 hrsMean: 8.7 hrs≥1hr: 93%

    The long awaited sequel to "Heart's Medicine - Time to Heal". An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring doctor at Little Creek Hospital!

    Why similar: Medical Sim 78.9% ★, Simulation 11.3%, Adventure 3.7%, Indie 3.7%, Story Rich 2.4%

  19. #19 Hot Seat Triage
    82% matchNo user reviews2026
    Dev: System Two Games
    Windows

    Triage is easy until your own brain starts lying to you. Pick patients from a crowded ER, question them under time pressure, and call NOW, SOON or WAIT before their aura fades. Every case hides a cognitive bias built to fool you. Made by an emergency physician.

    Why similar: Medical Sim 65.9% ★, Simulation 10%, Management 9.9%, Choices Matter 6.8%, Resource Management 4.1%

  20. #20 Brain Bomb
    82% matchNo user reviews2027
    Dev: Sea of GhostsPub: PlayWay S.A.
    Windows

    Concepts are bombs. Association is death. An cult-like anti-utopian psychological horror puzzle game. The subject has a concept bomb implanted in brain. If a subject thinks of the [Fuse Word], their head detonates. You, as the "cognitive bomb defuser", dismantling the deadly "brain bomb".

    Why similar: Medical Sim 61.1% ★, Detective 16.7%, Puzzle 8%, Simulation 6.9%, Atmospheric 5.1%

  21. #21 Medical verdict
    83% matchMixed57% of 53 reviews2018
    Dev: Volokitin Andrey
    Windows

    Here is a fun simulator of passing a medical examination in the Chelyabinsk clinic with realistic graphics and interesting gameplay! Take the coronavirus test! Collect as many virtual health points as you can, but remember ... this is just a game!

    Why similar: Medical Sim 83.9% ★, Simulation 12%, Indie 4.1%

  22. #22 Smile More
    79% matchVery Positive95% of 347 reviews2026
    Dev: Pixel Poxet
    Windows · Mac

    A short medical simulation horror game with multiple endings where the imperfect are made HAPPY. Perform tasks and operations on sedated patients to fix their defects before submitting your files to the Ministry of Happiness & Peace!

    Why similar: Medical Sim 57.7% ★, Dystopian 11.9%, Stylized 7.8%, Simulation 6.7%, Atmospheric 4.8%

  23. #23 Two Point Hospital
    81% matchVery Positive92% of 35,001 reviews2018
    Dev: Two Point StudiosPub: SEGA
    Windows · Mac · Linux
    Median: 5.5 hrsMean: 35.4 hrs≥1hr: 89%

    Design stunning hospitals, cure peculiar illnesses and manage troublesome staff as you spread your budding healthcare organisation across Two Point County.

    Why similar: Medical Sim 71.4% ★, Management 15.8%, Simulation 11.1%, Indie 1.1%, Singleplayer 0.5%

  24. #24 Field Hospital: Dr. Taylor's Story
    81% matchVery Positive89% of 112 reviews2020
    Dev: Gard Interactive
    Windows · Mac

    Field Hospital is a text-based bureaucratic detective game about hard decisions. Decide who to treat and whom to refuse. Face consequences. Study patients’ info and read their stories. Investigate the tangled case of Dr. Taylor.

    Why similar: Medical Sim 37.4% ★, Detective 13.1%, Point & Click 10.3%, Choices Matter 8.9%, Dark 8.4%

  25. #25 Do No Harm
    78% matchMostly Positive75% of 950 reviews2025
    Dev: Darts Games
    Windows
    Median: 2.3 hrsMean: 5.7 hrs≥1hr: 75%

    Lovecraftian Doctor Simulator. Diagnose patients by analyzing unsettling symptoms and treat them using your Book of Medicine. Make moral choices — decide who to save or kill, discover whom to trust, and unlock multiple endings! Can you endure 30 days of perilous decisions?

    Why similar: Medical Sim 51.6% ★, Choices Matter 9.8%, Point & Click 8.1%, Dark 7.5%, Management 6.5%

  26. #26 Dr. Cares - Amy's Pet Clinic
    80% matchMostly Positive79% of 77 reviews2018
    Dev: NitrealPub: GameHouse
    Windows · Mac

    Get ready to test your vet skills in Dr. Cares - Amy's Pet Clinic!

    Why similar: Medical Sim 81.7% ★, Simulation 14%, Adventure 4.3%

  27. #27 Tell me your Problem
    78% matchNo user reviews
    Dev: Alzakprod.Games
    Windows · Mac

    You think you’re healthy? There’re no healthy people — just those who haven’t been checked enough. And you definitely have problems. Try this pill. And, by the way, that’ll be five gold coins from you. A simulator of a rural psychiatrist who badly needs money.

    Why similar: Medical Sim 43.7% ★, Simulation 13.7%, Management 12.6%, Visual Novel 7.4%, Puzzle 6.6%

  28. #28 Reanimation Inc.
    79% matchVery Positive81% of 134 reviews2019
    Dev: Dmitrii Lomakin
    Windows

    Reanimation inc is a completely realistic simulation - real urgent conditions and diseases, real protocols of care used in an ambulance, realistic simulation of the body! Do you like realistic games about medicine and simulators, games you need to think about? You 'll be happy!

    Why similar: Medical Sim 83.5% ★, Simulation 12.4%, Indie 4.1%

  29. #29 Welcome Demon
    76% match4 user reviews75% of 4 reviews2026
    Dev: NurRam
    Windows

    You are a dungeon warden. Sitting in the chair of the previous warden you killed, you must cleanse yourself of your sins within 666 hours. Place the incoming demons into six different dungeons based on your information, intuition, and limited resources.

    Why similar: Medical Sim 43.2% ★, Choices Matter 11.9%, Point & Click 10.7%, Simulation 8.7%, Management 7.4%

  30. #30 Over the Counter
    77% matchVery Positive91% of 418 reviews2022
    Dev: Brody Rampono
    Windows · Mac · Linux

    A pharmaceutical business management game.

    Why similar: Medical Sim 69.6% ★, Resource Management 11.7%, Simulation 11%, Pixel Graphics 4.9%, 2D 2.3%

  31. #31 Mad Tilly's - Magical Amulets
    77% matchNo user reviews
    Dev: Favorite Ice Cream Studios
    Windows · Mac

    Heal your patients from curses and possessions as a shunned witch doctor in this creepy, cozy witch-life adventure: Care for your plants, craft magical amulets and analyse what is wrong with your neighbors so they start trusting in magic again. Make mythical new friends and heal what is broken.

    Why similar: Medical Sim 46.5% ★, Detective 12.3%, Choices Matter 9.3%, Dark 8.4%, Puzzle 6.6%

  32. #32 Donor Clinic Simulator
    76% matchNo user reviews
    Dev: 2 Stula Games
    Windows

    Manage your own reproductive medicine clinic! Choose donors based on their physical traits, research the effectiveness of biomaterials, upgrade the donor room, improve your laboratory, purchase new equipment, and help couples have a baby and become happy parents!

    Why similar: Medical Sim 62.3% ★, Management 15%, Simulation 14.6%, Choices Matter 6.2%, Indie 1.5%

  33. #33 BLACKWELL
    74% matchNo user reviews2027
    Dev: PolyDraft Studio
    Windows

    You are a Mech plague doctor treating a family infected by a disease that spreads through emotions, and mutates them into monsters. Your choices decide their fate.

    Why similar: Medical Sim 48% ★, Choices Matter 13.3%, Point & Click 10.2%, Dark 8.1%, Visual Novel 8%

  34. #34 Code Blue Idle
    73% match2 user reviews50% of 2 reviews2026
    Dev: Sulcus Games
    Windows

    A medical idle game with real hospital depth. Treat patients, hire staff, and unlock departments from the ED to the ICU — then watch your hospital run itself while you sleep.

    Why similar: Medical Sim 57.3% ★, Management 15%, Resource Management 12%, Simulation 8.1%, Atmospheric 4.1%

  35. #35 Surgeon Simulator VR: Meet The Medic
    75% matchMostly Positive77% of 598 reviews2016
    Dev: Bossa Studios
    Windows
    Median: 18 minMean: 1.6 hrs≥1hr: 14%

    Surgeon Simulator VR: Meet the Medic – be the Medic and operate on the Heavy in this free and exclusive teaser for the HTC Vive!

    Why similar: Medical Sim 90% ★, Simulation 8.1%, Indie 1.9%

  36. #36 Song of Farca
    74% matchMostly Positive79% of 1,693 reviews2021
    Dev: Wooden MonkeysPub: Alawar
    Windows · Mac · Linux
    Median: 3.5 hrsMean: 6.6 hrs≥1hr: 93%

    Hack into crime scenes, look for evidence, analyze data, interrogate criminals, track suspects and deal with the consequences of your decisions. This is a dark and brutal detective story with a Black Mirror-esque atmosphere of digital dominance and the narrative structure of a US crime procedural.

    Why similar: Detective 16.9%, Dystopian 13%, Choices Matter 12.2%, Point & Click 11.8%, Dark 7.6%

  37. #37 Magical Girl ER
    73% matchNo user reviews2026
    Dev: noranuco
    Windows

    A medical simulation where you examine and treat magical girls injured in kaiju disasters. With limited hospital beds and stamina, decide who to accept, who to refuse, and which treatment to choose.

    Why similar: Medical Sim 57.9% ★, Dark 9.9%, Visual Novel 8%, Resource Management 7.7%, Simulation 6.1%

  38. #38 Bacterium / 生命之旅
    75% matchPositive84% of 49 reviews2018
    Dev: Dragon Whisper GamePub: Zodiac Interactive
    Windows

    In the coming decades, a huge breakthrough in nano-medical technology will bring a new light to cure terminally ill patients. As a nano-robot operator, you will be involved in a battle between nanobots and diseases!

    Why similar: Medical Sim 79.3% ★, Simulation 12.3%, Indie 4.3%, Adventure 4%

  39. #39 The Death Handover
    72% matchNo user reviews
    Dev: Micronovae
    Windows

    Play as a novice mortician where every 'Death Handover' hides an unpaid debt. Through 'Soul-Returning,' relive final moments to break a five-life cycle. More than a simulation, it’s a rehearsal for death—until the next name on the list feels terrifyingly familiar.

    Why similar: Medical Sim 58.5% ★, Simulation 10.8%, Dark 5.9%, Point & Click 5.8%, Atmospheric 5.4%

  40. #40 Heart's Medicine - Time to Heal
    73% matchVery Positive94% of 884 reviews2016
    Dev: Blue GiraffePub: GameHouse
    Windows · Mac
    Median: 6.0 hrsMean: 12.2 hrs≥1hr: 92%

    An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring surgeon at Little Creek Hospital!

    Why similar: Medical Sim 82.4% ★, Simulation 7.9%, Indie 3.3%, Story Rich 3.3%, Adventure 2.4%

  41. #41 Rites & Receipts
    70% match2 user reviews67% of 9 reviews2026
    Dev: Infinite Inbox
    Windows

    Clock in at the Dark Magic Federation. As a ritual clerk, you must verify public requests, consult the manual, and process the paperwork for a world of petty hexes. Stamp requests, catch counterfeits, and avoid costly compliance fines. The quota is rising. Work starts now.

    Why similar: Point & Click 20%, Simulation 16%, Choices Matter 15.3%, Dark 11.3%, Dystopian 9.5%

  42. #42 Neo Harbor Rescue Squad
    71% matchMostly Positive77% of 13 reviews2024
    Dev: BancyCo
    Windows

    Live the life of a rookie paramedic through frantic minigame action and a wild, funny story. Juggle waves of patients with a battle-like triage system; master dozens of treatment minigames; and win the city's recognition from the rival fire department!

    Why similar: Medical Sim 62.3% ★, Simulation 14.3%, Visual Novel 10.1%, Choices Matter 6.4%, 2D 2.9%

  43. #43 Ultrasound
    71% matchNo user reviews
    Dev: Walter Woods
    Windows

    A sci-fi horror 3D point&click game. Use an ultrasound machine to diagnose and do surgery on a grotesque infection spreading aboard a space freighter. Craft meds, upgrade your machine, find new surgical tools, and restore ship systems before you collide with a star. Soon, something will be born.

    Why similar: Medical Sim 59% ★, Point & Click 10.5%, Management 9.9%, Puzzle 7.4%, Choices Matter 5.1%

  44. #44 Oops! INC. Emergency Center
    70% match6 user reviews100% of 6 reviews2026
    Dev: CCS
    Windows

    Run the galaxy’s most chaotic hospital in Oops! INC. Emergency Center! Play as a diploma-free robot doctor, diagnose bizarre space illnesses, craft the right remedies, and treat patients fast before insurance turns you into a fridge. Funny, frantic, and out of this world!

    Why similar: Medical Sim 73.1% ★, Management 13.4%, Simulation 8.6%, Puzzle 3.2%, Indie 1.3%

  45. #45 The Apothecary
    71% matchNo user reviews
    Dev: Rufalicious Gaming
    Windows

    The realm depends on your help: mix ingredients and create potions to cure wild, fantastical illnesses that befall your fellow citizens. But be warned, you are all on your own. Enjoy figuring out which ingredients work and which don't -- curing or killing those who ask for your help!

    Why similar: Medical Sim 68.7% ★, Point & Click 10%, Simulation 9.6%, Puzzle 5.6%, Resource Management 3.7%

  46. #46 Big Pharma
    72% matchMostly Positive77% of 1,939 reviews2015
    Dev: Twice CircledPub: Positech Games
    Windows · Mac · Linux
    Median: 5.8 hrsMean: 9.5 hrs≥1hr: 85%

    What if you had it in your power to rid the world of disease, to improve the lives of millions, to ease suffering and cure the sick… and earn a tidy profit? As the head of your own Pharmaceutical Conglomerate you have this power resting in your hands. Will you use it for good?

    Why similar: Medical Sim 60.1% ★, Management 15%, Simulation 7.9%, Resource Management 6.4%, Puzzle 6%

  47. #47 Dr. Oops!
    69% matchNo user reviews
    Dev: Black Tower Studios
    Windows

    Treat bizarre patients, solve outrageous medical mysteries, and pay off your crushing debt in this dark comedy deduction adventure! Every diagnosis relies on your observation, deduction, and some real-world knowledge. Pay off your debt, or skip a payment if needed, and fight for your freedom.

    Why similar: Medical Sim 57.8% ★, Point & Click 10.5%, Management 10.1%, Choices Matter 9.8%, Simulation 4.7%

  48. #48 Cutting Edge: Roots Of Mutation
    69% matchNo user reviews2027
    Dev: Wizbird Games LLC
    Windows

    Perform life-saving operations in this fast-paced surgery sim. As lizard surgeon Dr. Peri Maddock, you'll treat injuries, excise tumors, and hack corporate organs with speedy, surgical precision. The patient's life is in your claws!

    Why similar: Medical Sim 65.9% ★, Point & Click 12.5%, Visual Novel 7.8%, Simulation 7.1%, Story Rich 3.9%

  49. #49 Alien Morgue
    67% matchPositive95% of 37 reviews2026
    Dev: BurGum Games
    Windows

    You're an alien pathologist. Search the Database for alien physiology and dissect bodies to figure out what caused death. Find correct IDs by deceased's features and occupation. Discover weird stuff inside bodies and decide what to do with it. Follow protocols or personal request? Choices matter!

    Why similar: Medical Sim 52% ★, Detective 10.9%, Choices Matter 8.7%, Point & Click 8.6%, Simulation 5.5%

  50. #50 The Scarlet Thread
    68% matchNo user reviews
    Dev: ZeroTick Studio
    Windows

    A Victorian manor mystery in fine 1-bit ink, touched with scarlet. Read the accounts of different narrators, examine clothing and ledgers, and re-enact the night. Spotting lies is only part of the case: how much does an honest account really prove?

    Why similar: Detective 23.3%, Point & Click 14.6%, Choices Matter 9.9%, Puzzle 9.5%, Dark 9.5%

  51. #51 疑義照会ウォーズ
    70% matchMostly Negative30% of 20 reviews2021
    Dev: 薬学ゲーム開発プロジェクト
    Windows

    This is a full-fledged adventure game (selectable type) based on the theme of the pharmacist's job, "checking prescription. Determine if the prescription is correct, and if it is, make a "Questionable Inquiry" to the doctor!

    Why similar: Medical Sim 83% ★, Simulation 11.1%, 2D 3.4%, Indie 1.8%, Singleplayer 0.7%

  52. #52 RATTENTION!
    68% matchNo user reviews
    Dev: Till Night Games
    Windows · Mac · Linux

    RATTENTION! From now on, you manage a rat mafia. Hire the best gangsters from the worst. Earn the trust of the residents of the sewers. Decide who gets paid, whose tail to cover, and what you’ll sacrifice to survive. Just make sure no one finds out who you really work for.

    Why similar: Choices Matter 20.1%, Simulation 15.2%, Visual Novel 11.4%, Point & Click 9.6%, Atmospheric 8.3%

  53. #53 Scrutator Tenebris
    67% matchNo user reviews
    Dev: Empty Die Studio
    Windows

    Become a pathologist in a sinister mansion filled with unsolved mysteries. Examine bodies and make decisions that alter the course of the investigation. Your choices shape multiple story endings in this narrative-driven psychological horror — where every secret could cost your sanity.

    Why similar: Medical Sim 36.7% ★, Detective 20.3%, Simulation 6.9%, Atmospheric 6.6%, Pixel Graphics 6.3%

  54. #54 Good doktor
    69% matchMostly Negative21% of 14 reviews2019
    Dev: Niko Belik
    Windows

    Game simulator of the work of a general practitioner in a hospital. Your goal is to identify diseases in patients and achieve the highest level. Take care of the routine of the physician, control of coupons and carefully check each incoming patient for the presence of certain diseases.

    Why similar: Medical Sim 44.2% ★, Simulation 19.5%, Management 10.6%, Choices Matter 8%, Puzzle 6.8%

  55. #55 Very Human Doctor
    67% matchNo user reviews
    Dev: FreeMind S.A.
    Windows

    A Co(s)mic Medical Simulator where healing humanity is just your cover. Treat patients, secretly harvest DNA, experiment with bizarre alien technology, and keep your true identity hidden.

    Why similar: Medical Sim 70% ★, Simulation 13.2%, Management 7.5%, Stylized 3.9%, Resource Management 3.1%

  56. #56 Until The End
    67% matchMixed50% of 10 reviews2022
    Dev: Red Sorel Games
    Windows

    In Until The End, you play as Zoe, a young nurse who has just graduated. At the Montagne Institute, you will help her make the best decisions for the well-being of her patients in a palliative care unit.

    Why similar: Medical Sim 57.2% ★, Choices Matter 11.9%, Visual Novel 8.6%, Simulation 7.2%, Pixel Graphics 7%

  57. #57 Save Us, Doctor Faust!
    66% matchNo user reviews2027
    Dev: MIWAVV GAMES
    Windows

    Save Us, Doctor Faust! is an immersive medieval doctor simulator where you diagnose diseases, study medicine, and craft remedies from raw ingredients. Examine your patients, grind and distill ingredients, experiment with recipes — and remember: one mistake could cost a life.

    Why similar: Medical Sim 53.4% ★, Management 10.7%, Dark 10%, Resource Management 8.8%, Choices Matter 6.8%

  58. #58 Royal Dental
    65% match3 user reviews100% of 3 reviews2026
    Dev: Visionaire Labs
    Windows

    Rise from peasant dentist to royal healer in this quirky medieval dental simulation RPG. Treat patients, upgrade tools, improve your clinic, expand your knowledge, and restore Princess Penelope’s legendarily awful smile, all while facing sabotage from a jealous prince.

    Why similar: Medical Sim 69.3% ★, Management 9.3%, Simulation 8.3%, Resource Management 6.3%, Stylized 4.9%

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