- #1 Two Point Hospital
96% matchVery Positive92% of 34,720 reviews2018
Dev: Two Point StudiosPub: SEGA
Windows · Mac · Linux
Median: 5.4 hrsMean: 35.2 hrs≥1hr: 89%
Design stunning hospitals, cure peculiar illnesses and manage troublesome staff as you spread your budding healthcare organisation across Two Point County.
Why similar: Medical Sim 66.4% ★, Management 12.3%, Simulation 9.3%, Funny 4.9%, Comedy 4.1%
- #2 Мне только спросить!
96% matchNo user reviews
Dev: Каракули
Windows
"I just want to ask!" is a medical registrar simulator with time management elements set in a provincial Russian hospital, featuring humorous elements. Your main task is to help patients, but each one has their own story.
Why similar: Medical Sim 65.4% ★, Time Management 12.4%, Management 9.3%, Simulation 6.9%, Comedy 5.1%
- #3 Fable Hospital
94% matchMostly Positive73% of 89 reviews2025
Dev: AMGames TC
Windows
Fable Hospital is a medieval hospital management simulator with a touch of fantasy and humor. Cure hilarious diseases, manage an eccentric team, and gather resources in a world full of satire and fun.
Why similar: Medical Sim 51% ★, Medieval 12%, Management 8.3%, Resource Management 7.4%, Simulation 6.3%
- #4 Hospital Manager
95% matchMixed46% of 255 reviews2015
Dev: CCCPPub: Microids Indie
Windows · Mac
Median: 1.1 hrsMean: 9.5 hrs≥1hr: 56%
Experience something novel, bursting with extraordinary phenomena and strange situations in your hospital! Only you have the power to make the best decisions and to make your hospital the most popular one! But beware: Several events will add some spice to your life! Embark on the career of your life!
Why similar: Medical Sim 75.2% ★, Management 16.6%, Simulation 8.2%
- #5 Vital Signs: Emergency Department
93% matchMixed57% of 74 reviews2020
Dev: BreakAway Games
Windows · Mac
Play a doctor in Vital Signs: Emergency Department and challenge your medical knowledge to help treat a wide array of cases who come into the ER.
Why similar: Medical Sim 63.6% ★, Text-Based 14.6%, Time Management 12.6%, Simulation 5.9%, Stylized 2.7%
- #6 The Apothecary
92% matchNo user reviews
Dev: Rufalicious Gaming
Windows
The realm depends on your help: mix ingredients and create potions to cure wild, fantastical illnesses that befall your fellow citizens. But be warned, you are all on your own. Enjoy figuring out which ingredients work and which don't -- curing or killing those who ask for your help!
Why similar: Medical Sim 62.6% ★, RPG 9.2%, Simulation 7.8%, Text-Based 7.6%, Medieval 6.5%
- #7 Oops! INC. Emergency Center
91% match5 user reviews100% of 5 reviews2026
Dev: CCS
Windows
Run the galaxy’s most chaotic hospital in Oops! INC. Emergency Center! Play as a diploma-free robot doctor, diagnose bizarre space illnesses, craft the right remedies, and treat patients fast before insurance turns you into a fridge. Funny, frantic, and out of this world!
Why similar: Medical Sim 66.6% ★, Management 10.3%, Funny 7.8%, Simulation 7.1%, Comedy 5.7%
- #8 Heart's Medicine - Hospital Heat
91% matchVery Positive96% of 366 reviews2017
Dev: Blue GiraffePub: GameHouse
Windows · Mac
Median: 5.1 hrsMean: 8.7 hrs≥1hr: 93%
The long awaited sequel to "Heart's Medicine - Time to Heal". An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring doctor at Little Creek Hospital!
Why similar: Medical Sim 79.7% ★, Simulation 10.2%, Time Management 8%, Indie 2.2%
- #9 Night Shift Hospital
90% matchNo user reviews
Dev: Knitted CatsPub: Polden Publishing
Windows
A chaotic co-op job sim for up to 4 players about night-shift doctors. Handle a bizarre stream of patients, diagnose illnesses, and assign people to the correct treatment zones. Work as a team, get through nightly crises, and try your best not to get fired!
Why similar: Medical Sim 62.8% ★, Simulation 11%, Comedy 9.9%, Management 5.9%, Funny 3.8%
- #10 Heart's Medicine - Time to Heal
89% matchVery Positive94% of 883 reviews2016
Dev: Blue GiraffePub: GameHouse
Windows · Mac
Median: 6.0 hrsMean: 12.1 hrs≥1hr: 92%
An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring surgeon at Little Creek Hospital!
Why similar: Medical Sim 78% ★, Time Management 13%, Simulation 6.7%, Indie 1.9%, Singleplayer 0.3%
- #11 Medical Diagnostic Simulator
89% matchMostly Negative29% of 17 reviews2024
Dev: Arktos Cat
Windows
Play as a general practitioner in this text-based medical simulation game. Consult, examine, and diagnose your patients in your own medical practice.
Why similar: Medical Sim 65.1% ★, Text-Based 19.5%, Simulation 13.8%, Indie 1.1%, Singleplayer 0.5%
- #12 Mask of the Plague Doctor
88% matchVery Positive86% of 64 reviews2020
Dev: Choice of Games
Windows · Mac · Linux
Stop a deadly plague in a medieval fantasy tale of swords and surgery! Unearth medical knowledge, prevent the town’s purge, or plot your own escape.
Why similar: Medical Sim 52.2% ★, Text-Based 17.1%, Medieval 15%, RPG 12.4%, Indie 2.8%
- #13 Bacterium / 生命之旅
87% matchPositive84% of 49 reviews2018
Dev: Dragon Whisper GamePub: Zodiac Interactive
Windows
In the coming decades, a huge breakthrough in nano-medical technology will bring a new light to cure terminally ill patients. As a nano-robot operator, you will be involved in a battle between nanobots and diseases!
Why similar: Medical Sim 76.3% ★, Simulation 10.7%, RPG 10.5%, Indie 2.5%
- #14 Dr Greenstuff
86% matchVery Positive87% of 149 reviews2018
Dev: Black DiskettePub: Black Diskette Studio
Windows
Discover the life of Dr Greenstuff, grow marijuana, coca, make meth', drugs and more to keep your legal/illegal business running.
Why similar: Medical Sim 79.7% ★, Simulation 11.8%, Resource Management 5.8%, Indie 2.7%
- #15 Surgeon Simulator VR: Meet The Medic
86% matchMostly Positive77% of 589 reviews2016
Dev: Bossa Studios
Windows
Median: 18 minMean: 1.7 hrs≥1hr: 14%
Surgeon Simulator VR: Meet the Medic – be the Medic and operate on the Heavy in this free and exclusive teaser for the HTC Vive!
Why similar: Medical Sim 88.2% ★, Simulation 7.1%, Funny 3.6%, Indie 1.1%
- #16 Medical verdict
85% matchMixed57% of 53 reviews2018
Dev: Volokitin Andrey
Windows
Here is a fun simulator of passing a medical examination in the Chelyabinsk clinic with realistic graphics and interesting gameplay! Take the coronavirus test! Collect as many virtual health points as you can, but remember ... this is just a game!
Why similar: Medical Sim 86.4% ★, Simulation 11.1%, Indie 2.5%
- #17 Reanimation Inc.
84% matchVery Positive84% of 130 reviews2019
Dev: Dmitrii Lomakin
Windows
Reanimation inc is a completely realistic simulation - real urgent conditions and diseases, real protocols of care used in an ambulance, realistic simulation of the body! Do you like realistic games about medicine and simulators, games you need to think about? You 'll be happy!
Why similar: Medical Sim 86.1% ★, Simulation 11.4%, Indie 2.5%
- #18 Fun Hospital
84% matchMixed64% of 600 reviews2018
Dev: OrangesGame Technology Limited
Windows · Mac
Median: 1.2 hrsMean: 32.8 hrs≥1hr: 52%
Build your own theme hospital! Here, you might meet patients with a lot of hair, or no hair; strange aliens, evil guy, super hero…
Why similar: Medical Sim 75.9% ★, Simulation 12.8%, Strategy 4.5%, RPG 4.1%, Indie 2.6%
- #19 Epi Derick
82% matchPositive80% of 10 reviews2025
Dev: Fireslug Studios
Windows
You run the only pharmacy in a rural town. Each face at the counter is the same, each ailment slightly different. Provide Care - Follow Our Rules - Stay Safe.
Why similar: Medical Sim 64.3% ★, Simulation 10%, Management 7.7%, Resource Management 5.2%, Multiple Endings 4.2%
- #20 Dr. Cares - Amy's Pet Clinic
83% matchMostly Positive79% of 76 reviews2018
Dev: NitrealPub: GameHouse
Windows · Mac
Get ready to test your vet skills in Dr. Cares - Amy's Pet Clinic!
Why similar: Medical Sim 86.7% ★, Simulation 13.3%
- #21 小邦迪的奇妙冒险
82% matchPositive89% of 18 reviews2021
Dev: Puyuan YePub: Band-Aid
Windows · Mac
在《小邦迪的奇妙冒险》中与小邦迪一同学习急救知识,拯救吴家于各种急症之中。
Why similar: Medical Sim 72.7% ★, RPG 13.9%, Simulation 7.6%, Linear 4.5%, Indie 1%
- #22 Scalpel, Please!
81% matchNo user reviews
Dev: WoolCat Games
Windows
Scalpel, Please! is a ridiculous medical simulator where you assist a blindfolded surgeon. Provide tools, talk to him, and give your full support. But be careful: he’ll remember everything you do and react accordingly. Will you manage to keep your job?
Why similar: Medical Sim 68.3% ★, Simulation 11.9%, Comedy 8.9%, Funny 7%, Multiple Endings 2.9%
- #23 Cutting Edge: Roots Of Mutation
81% matchNo user reviews2026
Dev: Wizbird Games LLC
Windows
Perform life-saving operations in this fast-paced surgery sim. As lizard surgeon Dr. Peri Maddock, you'll treat injuries, excise tumors, and hack corporate organs with speedy, surgical precision. The patient's life is in your claws!
Why similar: Medical Sim 65.8% ★, Text-Based 11.8%, Time Management 9.5%, Simulation 6.4%, Cartoony 3.1%
- #24 Tell me your Problem
80% matchNo user reviews
Dev: Alzakprod.Games
Windows · Mac
You think you’re healthy? There’re no healthy people — just those who haven’t been checked enough. And you definitely have problems. Try this pill. And, by the way, that’ll be five gold coins from you. A simulator of a rural psychiatrist who badly needs money.
Why similar: Medical Sim 46.6% ★, Simulation 13.1%, Comedy 12.7%, Management 11.3%, Multiple Endings 10.1%
- #25 Over the Counter
79% matchVery Positive91% of 408 reviews2022
Dev: Brody Rampono
Windows · Mac · Linux
A pharmaceutical business management game.
Why similar: Medical Sim 74.6% ★, Resource Management 10.9%, Simulation 10.5%, Strategy 3.6%, Singleplayer 0.4%
- #26 SimShock2025
79% match7 user reviews75% of 8 reviews2025
Dev: Pablo Kessler SaizPub: Pablo Kessler
Windows · Mac
SimShock2025 is a free, bilingual (EN/ES) hemodynamic shock simulator. Treat cardiogenic, hemorrhagic, and septic shock using real drugs and interventions. Written in PureBasic, available for Mac and Windows. Apple-signed and notarized.
Why similar: Medical Sim 61% ★, Simulation 12.5%, Text-Based 12.3%, Funny 6.3%, Resource Management 4.3%
- #27 本草归元录
78% matchVery Positive80% of 155 reviews2025
Dev: Orange Paper StudioPub: CC_Games
Windows
"Herbals tycoon" is a game that combines ancient style with deep management strategy, bringing players into a mysterious and fantastic world of traditional Chinese medicine. Here, you are not only a healer but also an explorer, manager, and inheritor, writing your own herbal legend every moment.
Why similar: Medical Sim 58.1% ★, Time Management 11.5%, RPG 8.1%, Medieval 8%, Simulation 7.9%
- #28 Surgineer
78% matchNo user reviews
Dev: Holonautic
Linux
Have you ever dreamed of being a real surgeon? Well… you will not learn that here. Discover a crazy universe where you get the opportunity to be the greatest or most terrible doctor.
Why similar: Medical Sim 77.2% ★, Simulation 10.1%, Funny 9.8%, Logic 1.8%, Indie 0.8%
- #29 Doctor Dash ASMR Hospital
77% matchVery Positive89% of 97 reviews2024
Dev: Friedegggames OUPub: Brightika, Inc.
Windows
💊 Your dream hospital awaits! 🏥❤️ Addictive levels and unique locations ✈️ Hours of entertainment in the time-management genre ⏰
Why similar: Medical Sim 72.5% ★, Simulation 11.3%, Management 9.9%, Time Management 5.7%, Singleplayer 0.5%
- #30 Morbus: The Burden Of The Apothecary
77% matchNo user reviews
Dev: Viktor PekarPub: Introverse Interactive
Windows · Linux
A top-down plague simulation RPG set in a living medieval tapestry. Play the last apothecary in a dying town treating the sick, containing the outbreak, and navigating the politics of factions who'd sooner see you burn.
Why similar: Medical Sim 66.3% ★, Medieval 13.5%, RPG 6.2%, Simulation 5.6%, Stylized 4.6%
- #31 Opawration!
76% matchNo user reviews
Dev: chinchingames
Windows
A 2D, veterinarian horror game. In this game, select the appropriate treatment and treat patients with topical products injections, surgeries. Treat patients over the course of 7 days, using the in-game computer to research the best treatment option. Playtime is 2 hours.
Why similar: Medical Sim 78.9% ★, Simulation 6.6%, Multiple Endings 6.2%, RPG 3.7%, Cartoony 3.3%
- #32 Golden Years Nursing Home
76% matchNo user reviews2026
Dev: Iron Tank StudiosPub: Concaide
Windows
A newly hired night‑shift nurse faces unsettling events in the soon‑to‑close Golden Years Nursing Home. Quiet halls, flickering lights, and shifting rooms hint at a past the residents won’t speak of. A slow‑burn psychological horror with no combat—just dread.
Why similar: Medical Sim 69.7% ★, Management 10.5%, Simulation 5.6%, Resource Management 5.2%, Multiple Endings 4.7%
- #33 疑義照会ウォーズ
75% matchMostly Negative30% of 20 reviews2021
Dev: 薬学ゲーム開発プロジェクト
Windows
This is a full-fledged adventure game (selectable type) based on the theme of the pharmacist's job, "checking prescription. Determine if the prescription is correct, and if it is, make a "Questionable Inquiry" to the doctor!
Why similar: Medical Sim 87.9% ★, Simulation 10.6%, Indie 1.1%, Singleplayer 0.4%
- #34 Donor Clinic Simulator
74% matchNo user reviews
Dev: 2 Stula Games
Windows
Manage your own reproductive medicine clinic! Choose donors based on their physical traits, research the effectiveness of biomaterials, upgrade the donor room, improve your laboratory, purchase new equipment, and help couples have a baby and become happy parents!
Why similar: Medical Sim 69.8% ★, Simulation 14.7%, Management 14.3%, Indie 1%, Singleplayer 0.3%
- #35 Prescribe and Pray
72% matchMostly Positive74% of 74 reviews2026
Dev: Nuclear Rabbits
Windows
Awaken the incompetent doctor within you! Diagnose strange patients, examine their absurd symptoms… and prescribe treatments that could change their lives… or cut them short. Your actions will have consequences.
Why similar: Medical Sim 63.1% ★, Comedy 14%, Multiple Endings 7.9%, Management 7.6%, Simulation 6.8%
- #36 Pharmacy Simulator
73% matchMixed59% of 252 reviews2024
Dev: Altai Entertainment
Windows
Experience a realistic pharmacy management experience with Pharmacy Simulator. Set up your shop, decorate it as you wish, and purchase over a hundred types of medications. Pharmacy Simulator offers you an incredibly realistic pharmacy experience. Prove your skills in a challenging economic system.
Why similar: Medical Sim 63.3% ★, Time Management 12.8%, Simulation 12.6%, Management 5.8%, Resource Management 4.4%
- #37 Surgeon Simulator: Experience Reality
74% matchMixed58% of 1,245 reviews2016
Dev: Bossa Studios
Windows
Median: 54 minMean: 2.2 hrs≥1hr: 47%
Surgeon Simulator is bringing the ER to VR! The most critically acclaimed and infamous surgery simulation game as you have never seen it before! Featuring all of the surgeries and twisted humour of the original favourite plus a few new surprises...
Why similar: Medical Sim 83.7% ★, Simulation 10%, Funny 4.4%, Indie 1.8%
- #38 Code Blue Idle
73% matchNo user reviews
Dev: Sulcus Games
Windows · Mac · Linux
A medical idle game with real hospital depth. Treat patients, hire staff, and unlock departments from the ED to the ICU — then watch your hospital run itself while you sleep.
Why similar: Medical Sim 62.7% ★, Management 13.9%, Resource Management 11.4%, Simulation 8%, Strategy 2.9%
- #39 Heart's Medicine - Season One
73% matchVery Positive81% of 121 reviews2020
Dev: Big Blue StudiosPub: GameHouse
Windows · Mac
Can you be counted on in an emergency? 🚑
Why similar: Medical Sim 61.3% ★, Time Management 15%, Simulation 14.7%, Romance 5.9%, Indie 3.2%
- #40 Mind Verge
72% matchNo user reviews
Dev: 岚爱万七
Windows
Step into a psychosomatic clinic as a therapist. Diagnose patients with shooting mechanics and treat them via rhythmic QTEs. Manage dual sanity: you relieve others' mental pain, while endless emotions wear on your own mind. Experience mutual healing — healers carry pain too.
Why similar: Medical Sim 70.1% ★, Simulation 11.9%, RPG 8.5%, Management 5.8%, Strategy 3%
- #41 Dr. Chatelet: Faith 神医
71% matchVery Positive85% of 132 reviews2022
Dev: MuccyGames
Windows · Mac
Amputations, bloodletting, alchemy - all of which seem unthinkable today - were the treatment options that medieval doctors revered. You must face challenges one after another and experience gains and losses in the course of your constant adventures
Why similar: Medical Sim 61.5% ★, Medieval 13.2%, RPG 8.2%, Simulation 7.8%, Multiple Endings 5%
- #42 Psyhonds
70% matchMostly Positive70% of 10 reviews2026
Dev: Meriteri GamesPub: Terrabyte Games
Windows
A satirical mental hospital survival simulator: control four unstable characters, craft from junk, forge dubious alliances, communicate with patients and staff, and choose between a quiet life in a ward, a riot, or a risky escape to freedom.
Why similar: Medical Sim 83.2% ★, Simulation 7.8%, RPG 5.5%, Stylized 2.3%, Indie 0.9%
- #43 Love Hospital
71% matchNo user reviews100% of 1 reviews2026
Dev: KXMstudio
Windows
"Love Hospital" is a comedy romance simulation game where you can enjoy sweet relationships with beautiful nurses. Experience the fun and laughter-filled romance unfolding in the hospital!"
Why similar: Medical Sim 65.2% ★, Text-Based 12.2%, Comedy 10.1%, Romance 6.4%, Simulation 5.6%
- #44 型神:初见
70% matchNo user reviews
Dev: 戏宫科技
Windows
全球首款医美手术模拟与视觉小说相结合的游戏!你将通过神奇的医美技术改变命运,体验30场精密手术,揭开时间与美丽背后的秘密。你的每一次操作,都在重塑他人的人生。
Why similar: Medical Sim 79.5% ★, Comedy 11.1%, Simulation 7.5%, Indie 1.5%, Singleplayer 0.5%
- #45 Human Constructor VR
71% match3 user reviews67% of 3 reviews2020
Dev: Exxit
Windows
Human Constructor VR is a virtual reality application designed for detailed study of the human structure and individual organs, bones, and muscles. This application contains only the anatomy of the male human body.
Why similar: Medical Sim 90.7% ★, Simulation 8.7%, Singleplayer 0.6%
- #46 MediSim: Emergency Response
70% matchNo user reviews
Dev: Mehmet Hilmi Değirmenci
Windows
As a young doctor, save lives in emergencies, advance from a health center to a major hospital, and manage your own facility. Perform first aid, and diagnostics, take on ambulance and helicopter missions, and build your medical team. A realistic medical simulation where every decision matters!
Why similar: Medical Sim 78.9% ★, Simulation 14.2%, Management 6.6%, Singleplayer 0.3%
- #47 Physician Simulator
69% matchNo user reviews
Dev: Pavel Shishkin
Windows · Mac · Linux
A district physician simulator. See patients, review lab results, make diagnoses and write prescriptions. Real doctors say they recognize themselves. Every decision has consequences.
Why similar: Medical Sim 55.6% ★, RPG 15.7%, Simulation 13.6%, Comedy 6.8%, Multiple Endings 3.7%
- #48 Nursing Simulator—Code Ube
67% matchNo user reviews100% of 3 reviews2026
Dev: Mobile Nursing LLC
Windows · Mac · Linux
When things aren't as they seem, nobody stands against fate but one nurse. Play as Karen—a nurse who saves lives and kicks butt! Complete tasks, give meds, and document assessments. But when night comes, beware of those who try to steer you away from what's right.
Why similar: Medical Sim 81.1% ★, Simulation 16.9%, Indie 1.2%, Singleplayer 0.7%
- #49 Weedcraft Inc
69% matchVery Positive80% of 1,685 reviews2019
Dev: Vile MonarchPub: Devolver Digital
Windows · Mac
Median: 4.7 hrsMean: 11.2 hrs≥1hr: 89%
Weedcraft Inc explores the business of producing, breeding and selling weed in America, delving deep into the financial, political and cultural aspects of the country's complex relationship with this troublesome and promising plant.
Why similar: Medical Sim 48.8% ★, Simulation 21.3%, Management 15%, Strategy 6.5%, Indie 4%
- #50 Big Pharma
69% matchMostly Positive77% of 1,935 reviews2015
Dev: Twice CircledPub: Positech Games
Windows · Mac · Linux
Median: 5.8 hrsMean: 9.5 hrs≥1hr: 85%
What if you had it in your power to rid the world of disease, to improve the lives of millions, to ease suffering and cure the sick… and earn a tidy profit? As the head of your own Pharmaceutical Conglomerate you have this power resting in your hands. Will you use it for good?
Why similar: Medical Sim 67.5% ★, Management 14.3%, Simulation 8%, Resource Management 6.3%, Strategy 2.2%
- #51 Gaming Burnout Treatment Center
65% matchNo user reviews99% of 517 reviews2026
Dev: Wave Games
Windows
Digital ED Treatment Center is a random launcher for players in a gaming slump. We help you rediscover the joy of play and unearth hidden gems buried in your library. Click to start your treatment and reignite your gaming vigor!
Why similar: Medical Sim 61.9% ★, Funny 9.9%, Comedy 9.6%, Text-Based 9.4%, Simulation 7.7%
- #52 X-Ray Pet Hospital
68% matchNo user reviews2026
Dev: X-Ray Pet Hospital
Windows
Run your own animal hospital simulator and diagnose pets using real-time X-ray scanning. Inspect animals, uncover hidden objects, solve medical mysteries, and treat patients in this veterinary simulation game before it’s too late.
Why similar: Medical Sim 71.6% ★, Simulation 13.1%, Funny 7.2%, Management 6.9%, Indie 0.9%
- #53 PSY in Apocalypse
67% matchNo user reviews
Dev: Quantum Strawberry
Windows
PSY in Apocalypse는 사실적인 2D 정신과 어드벤처 게임입니다. 여러분은 게임 속에서 정신과 의사가 되어 환자들을 직접 치료하게 됩니다. 포스트 아포칼립스 세계를 의사의 관점이라는 다소 새로운 시각으로 이야기를 풀어나가게 됩니다.
Why similar: Medical Sim 86.4% ★, Linear 6.2%, Simulation 5.3%, Indie 1.5%, Singleplayer 0.6%
- #54 中医模拟传承人
67% matchPositive87% of 15 reviews2024
Dev: guizhi0011
Windows
A game where everyone can learn traditional Chinese medicine.
Why similar: Medical Sim 82.4% ★, Simulation 14.8%, Indie 2.4%, Singleplayer 0.4%
- #55 My Universe - Pet Clinic Cats & Dogs
68% matchMixed62% of 29 reviews2020
Dev: It Matters GamesPub: Microids
Windows
Discover the veterinary profession and help cats and dogs that need you. An injury, fever, an animal that refuses to eat: it’s up to you to act!
Why similar: Medical Sim 71.9% ★, Simulation 10.4%, Time Management 9.7%, Management 7.5%, Singleplayer 0.5%