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Games Like No Emergency: Pestilence

60+ similar titles based on shared tags and player behavior. Themes include Simulation, Medical Sim, Singleplayer, Indie.

No Emergency: Pestilence header art

No Emergency: Pestilence plunges players into the epicenter of a mysterious epidemic, where every arriving patient could be carrying a mutating pathogen, and a single mistake in a prescription turns the cure into poison.

Reviews: No user reviews — 50%
Released: 2026-09-18
Developer: 20 July
Genres: Indie, Simulation, Early Access
Platforms: Windows

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  2. #2 Before I Turn: Survival Auto Battler
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    Why similar: Medical Sim 39.5% ★, Outbreak Sim 36.9% ★, Time Management 12.4%, Simulation 6.4%, First-Person 2.1%

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    Windows

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    Why similar: Medical Sim 38.2% ★, Outbreak Sim 35.9% ★, Time Management 11.5%, Simulation 9.9%, 3D 2.3%

  4. #4 中国战疫
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    Why similar: Medical Sim 38.8% ★, Outbreak Sim 34.9% ★, Time Management 12.1%, Simulation 7.4%, Resource Management 4.7%

  5. #5 The Book of Plagues 2
    94% matchNo user reviews2027
    Dev: DiaMMax Games
    Windows

    False Death has come to Grizmar. The plague steals souls and turns bodies into soulless puppets, doomed to repeat the final hours of their lives forever. Can you survive as the city turns into a puppet theater?

    Why similar: Outbreak Sim 42.1% ★, Medical Sim 40.6% ★, Simulation 7.5%, Crafting 4.6%, Management 4%

  6. #6 Turbulence - Airplane Survival Simulator
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    Dev: True GamesPub: Idea Labs
    Windows

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    Why similar: Medical Sim 40.8% ★, Outbreak Sim 37.9% ★, Simulation 15.8%, First-Person 3.1%, Resource Management 2.2%

  7. #7 Мне только спросить!
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    Dev: Каракули
    Windows

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  8. #8 Save Us, Doctor Faust!
    92% matchNo user reviews2027
    Dev: MIWAVV GAMES
    Windows

    Save Us, Doctor Faust! is an immersive medieval doctor simulator where you diagnose diseases, study medicine, and craft remedies from raw ingredients. Examine your patients, grind and distill ingredients, experiment with recipes — and remember: one mistake could cost a life.

    Why similar: Medical Sim 41.9% ★, Outbreak Sim 28.8% ★, Simulation 6.5%, Management 6.3%, Crafting 5.9%

  9. #9 Hot Seat Triage
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    Dev: System Two Games
    Windows

    Triage is easy until your own brain starts lying to you. Pick patients from a crowded ER, question them under time pressure, and call NOW, SOON or WAIT before their aura fades. Every case hides a cognitive bias built to fool you. Made by an emergency physician.

    Why similar: Medical Sim 58.8% ★, Time Management 17.5%, Simulation 13.7%, Management 6.6%, Resource Management 2.6%

  10. #10 Heart's Medicine - Hospital Heat
    90% matchVery Positive96% of 366 reviews2017
    Dev: Blue GiraffePub: GameHouse
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    Median: 5.1 hrsMean: 8.7 hrs≥1hr: 93%

    The long awaited sequel to "Heart's Medicine - Time to Heal". An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring doctor at Little Creek Hospital!

    Why similar: Medical Sim 71.5% ★, Simulation 15.7%, Time Management 11%, Indie 1.7%

  11. #11 Bio Inc. Redemption
    89% matchVery Positive88% of 3,261 reviews2018
    Dev: DryGin Studios
    Windows
    Median: 2.4 hrsMean: 5.9 hrs≥1hr: 72%

    Bio Inc.: Redemption is a realistic simulation and strategy game in which you make life or death decisions. Create a deadly illness to infect and torment your victim or play as the head of a medical team and hopefully find a cure to save your human patient. Will you be the plague or preserve humanity?

    Why similar: Medical Sim 45.4% ★, Outbreak Sim 35.6% ★, Simulation 7.5%, Management 5.9%, Atmospheric 2.6%

  12. #12 Heart's Medicine - Time to Heal
    89% matchVery Positive94% of 884 reviews2016
    Dev: Blue GiraffePub: GameHouse
    Windows · Mac
    Median: 6.0 hrsMean: 12.2 hrs≥1hr: 92%

    An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring surgeon at Little Creek Hospital!

    Why similar: Medical Sim 69.9% ★, Time Management 18%, Simulation 10.4%, Indie 1.5%, Singleplayer 0.3%

  13. #13 Pandemic Crisis
    88% match9 user reviews100% of 9 reviews2020
    Dev: Thor Gaming
    Windows

    In the event of a global pandemic, would your first priority be preserving lives or saving the economy?

    Why similar: Outbreak Sim 42.2% ★, Medical Sim 39.8% ★, Simulation 10%, Resource Management 4.8%, Management 1.9%

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    Windows

    Shark Dentist is a unique horror roguelike where you play as a shark dentist. Your task is to treat the teeth of giant predators in a dark clinic while avoiding their deadly aggression. Balance tactics, luck, and limited resources to heal your patient without losing your own life.

    Why similar: Medical Sim 49.1% ★, Time Management 15.5%, Roguelike 13.2%, Simulation 12.3%, First-Person 4.2%

  15. #15 Hospital Manager
    86% matchMixed46% of 255 reviews2015
    Dev: CCCPPub: Microids Indie
    Windows · Mac
    Median: 1.1 hrsMean: 9.4 hrs≥1hr: 56%

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    Why similar: Medical Sim 72.4% ★, Management 14.1%, Simulation 13.5%

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    Windows

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    Why similar: Medical Sim 42.5% ★, Outbreak Sim 32% ★, Simulation 16.7%, Management 3.4%, Resource Management 2.6%

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    85% matchVery Positive87% of 149 reviews2018
    Dev: Black DiskettePub: Black Diskette Studio
    Windows

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    Why similar: Medical Sim 74.4% ★, Simulation 19%, Resource Management 4.5%, Indie 2.2%

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    Windows
    Median: 4.9 hrsMean: 10.1 hrs≥1hr: 87%

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    Why similar: Medical Sim 51.7% ★, Simulation 17.6%, Time Management 16.1%, Management 4.2%, First-Person 3.9%

  21. #21 Medical verdict
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    Dev: Volokitin Andrey
    Windows

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    Why similar: Medical Sim 80.2% ★, Simulation 17.7%, Indie 2%

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    Why similar: Medical Sim 60.3% ★, Simulation 12.4%, Management 6.4%, Co-op 5.4%, Online Co-Op 4.7%

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    Windows

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    Why similar: Medical Sim 59.5% ★, Simulation 17.9%, Co-op 5.7%, Management 5.1%, 3D 4%

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    Dev: Areas RPub: PeopleFirstAI
    Windows

    “Hero Hospital” is a classic hospital management game: send in undercover agents and fake patient brokers, unleash dogs to cause crashes and chaos, dump trash and throw bombs, and even head into outbreak zones to fight viruses. The gameplay can be expanded endlessly.

    Why similar: Medical Sim 49.5% ★, Outbreak Sim 39.8% ★, Simulation 6.2%, Management 4.5%

  25. #25 The Attending
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    Dev: Abreu Data Works
    Windows

    You are the attending physician on the night shift. Your doctors work the cases — and report what they believe, not what's true. Read their workups, catch the miss before it walks out the door, and spend your trust where it counts. One night. One board. Everyone's yours.

    Why similar: Medical Sim 71.6% ★, Simulation 15.4%, Management 9.6%, Atmospheric 2.6%, Indie 0.6%

  26. #26 Reanimation Inc.
    79% matchVery Positive81% of 134 reviews2019
    Dev: Dmitrii Lomakin
    Windows

    Reanimation inc is a completely realistic simulation - real urgent conditions and diseases, real protocols of care used in an ambulance, realistic simulation of the body! Do you like realistic games about medicine and simulators, games you need to think about? You 'll be happy!

    Why similar: Medical Sim 79.8% ★, Simulation 18.2%, Indie 2%

  27. #27 Pharmacy Simulator: Big Pharma
    75% matchMixed42% of 12 reviews2026
    Dev: Yusuf Islam SeyhanPub: Inspector Studios
    Windows

    Build and manage your own pharmacy! Fulfill prescriptions, order medical supplies, and stock shelves. Experience a realistic life sim: manage your hunger, ride a bike, and sleep in your apartment. Hire staff to automate your retail tycoon business in this immersive open world simulator.

    Why similar: Medical Sim 57.3% ★, Simulation 17.2%, Time Management 10.6%, Management 7.7%, First-Person 2%

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    Dev: 2 Stula Games
    Windows

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    Why similar: Medical Sim 58.9% ★, Simulation 21.2%, Management 10.6%, First-Person 4.5%, 3D 3.8%

  29. #29 Two Point Hospital
    76% matchVery Positive92% of 35,001 reviews2018
    Dev: Two Point StudiosPub: SEGA
    Windows · Mac · Linux
    Median: 5.5 hrsMean: 35.4 hrs≥1hr: 89%

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    Why similar: Medical Sim 70.2% ★, Simulation 16.8%, Management 11.6%, Indie 0.6%, Multiplayer 0.5%

  30. #30 Epi Derick
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    Dev: Fireslug Studios
    Windows

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    Why similar: Medical Sim 62.3% ★, Simulation 16.6%, Management 6.6%, First-Person 5.6%, Resource Management 4.1%

  31. #31 Symptoms of Infection
    73% matchNo user reviews91% of 69 reviews2026
    Dev: ORB Research & Broadcasting
    Windows · Linux

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    Why similar: Outbreak Sim 53% ★, Medical Sim 31.4% ★, Simulation 15%, Singleplayer 0.6%

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    77% matchMostly Positive79% of 77 reviews2018
    Dev: NitrealPub: GameHouse
    Windows · Mac

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    Why similar: Medical Sim 79.2% ★, Simulation 20.8%

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    77% matchMostly Positive77% of 598 reviews2016
    Dev: Bossa Studios
    Windows
    Median: 18 minMean: 1.6 hrs≥1hr: 14%

    Surgeon Simulator VR: Meet the Medic – be the Medic and operate on the Heavy in this free and exclusive teaser for the HTC Vive!

    Why similar: Medical Sim 84.7% ★, Simulation 11.7%, First-Person 1.6%, Multiplayer 1.1%, Indie 0.9%

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    74% matchNo user reviews
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    Windows · Linux

    A top-down plague simulation RPG set in a living medieval tapestry. Play the last apothecary in a dying town treating the sick, containing the outbreak, and navigating the politics of factions who'd sooner see you burn.

    Why similar: Medical Sim 57.9% ★, Outbreak Sim 33.4% ★, Simulation 8.4%, Singleplayer 0.3%

  35. #35 The Book of Plagues
    72% matchPositive90% of 31 reviews2026
    Dev: DiaMMax Games
    Windows

    The city is drowning in Plague. Panic, hunger, and fear are tearing it apart. You are the last one who can change its fate: heal it, hold it back from collapse… or drive it to ruin with your own hands!

    Why similar: Medical Sim 49.5% ★, Outbreak Sim 41.9% ★, Simulation 6.2%, Atmospheric 2.3%, Singleplayer 0.1%

  36. #36 Paws & Patches
    73% matchNo user reviews
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    Windows

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    Why similar: Medical Sim 61.2% ★, Time Management 18.3%, Simulation 8.6%, Management 7.4%, 3D 2.5%

  37. #37 Ice Rescue Simulator VR
    73% matchNo user reviews
    Dev: Sempiternal Rain
    Windows

    Ice Rescue Simulator VR – a fun ice emergency rescue simulator where a victim’s life is in your hands, and any wrong move can lead to failure!

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    74% match5 user reviews60% of 5 reviews2022
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    Windows

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    71% matchVery Positive88% of 99 reviews2024
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    Windows

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  40. #40 Ultrasound
    71% matchNo user reviews
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    Windows

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  41. #41 X-Ray Pet Hospital
    71% matchNo user reviews2026
    Dev: X-Ray Pet Hospital
    Windows

    Run your own animal hospital simulator and diagnose pets using real-time X-ray scanning. Inspect animals, uncover hidden objects, solve medical mysteries, and treat patients in this veterinary simulation game before it’s too late.

    Why similar: Medical Sim 60.6% ★, Simulation 19%, Management 5.2%, First-Person 4.3%, 3D 3.8%

  42. #42 Alarm112: Fire Unit
    69% matchMostly Positive72% of 24 reviews2026
    Dev: Control Room Labs
    Windows

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    Why similar: Outbreak Sim 38.7% ★, Time Management 22.4%, Simulation 22%, Management 8.8%, Resource Management 7.8%

  43. #43 MediSim: Emergency Response
    70% matchNo user reviews
    Dev: Mehmet Hilmi Değirmenci
    Windows

    As a young doctor, save lives in emergencies, advance from a health center to a major hospital, and manage your own facility. Perform first aid, and diagnostics, take on ambulance and helicopter missions, and build your medical team. A realistic medical simulation where every decision matters!

    Why similar: Medical Sim 67.2% ★, Simulation 20.7%, Management 5%, First-Person 3.9%, 3D 2.9%

  44. #44 40 Days [四十天]
    72% matchMixed54% of 13 reviews2017
    Dev: Black Phoenix Studio
    Windows · Mac

    40 Days is a special strategy simulation game related to infectious diseases spread all over the city. You, as ahead of the quarantine department, have been given full authority and manpower to contain the city, deal with different parties, virus in the city and most importantly find out the cure.

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  45. #45 Very Human Doctor
    69% matchNo user reviews
    Dev: FreeMind S.A.
    Windows

    A Co(s)mic Medical Simulator where healing humanity is just your cover. Treat patients, secretly harvest DNA, experiment with bizarre alien technology, and keep your true identity hidden.

    Why similar: Medical Sim 65.1% ★, Simulation 18.9%, First-Person 5.5%, Management 5.2%, 3D 2.2%

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    70% match9 user reviews89% of 9 reviews2021
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    Windows

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  47. #47 Royal Dental
    67% match3 user reviews100% of 3 reviews2026
    Dev: Visionaire Labs
    Windows

    Rise from peasant dentist to royal healer in this quirky medieval dental simulation RPG. Treat patients, upgrade tools, improve your clinic, expand your knowledge, and restore Princess Penelope’s legendarily awful smile, all while facing sabotage from a jealous prince.

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  48. #48 Psyhonds
    67% matchMostly Positive70% of 10 reviews2026
    Dev: Meriteri GamesPub: Terrabyte Games
    Windows

    A satirical mental hospital survival simulator: control four unstable characters, craft from junk, forge dubious alliances, communicate with patients and staff, and choose between a quiet life in a ward, a riot, or a risky escape to freedom.

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  49. #49 Bacterium / 生命之旅
    69% matchPositive84% of 49 reviews2018
    Dev: Dragon Whisper GamePub: Zodiac Interactive
    Windows

    In the coming decades, a huge breakthrough in nano-medical technology will bring a new light to cure terminally ill patients. As a nano-robot operator, you will be involved in a battle between nanobots and diseases!

    Why similar: Medical Sim 78.9% ★, Simulation 18.9%, Indie 2.2%

  50. #50 Clay Clinic
    67% matchNo user reviews
    Dev: Brightika, Inc.
    Windows

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  51. #51 Bio Inc. Classic
    67% matchNo user reviews2026
    Dev: DryGin Studios
    Windows

    Relive the original Bio Inc. experience, rebuilt from the ground up for PC to celebrate its 15th anniversary. Develop deadly diseases, cripple your victim’s body, and determine their ultimate fate in this biomedical strategy simulator.

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  52. #52 Heart's Medicine - Season One
    68% matchVery Positive81% of 121 reviews2020
    Dev: Big Blue StudiosPub: GameHouse
    Windows · Mac

    Can you be counted on in an emergency? 🚑

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  53. #53 Trojan Inc.
    70% matchMostly Negative36% of 33 reviews2017
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    Windows

    Will you be able to infect all devices of the world? «Trojan Inc.» - simulator, which will involve you in a world of computer viruses and trojans.

    Why similar: Outbreak Sim 83.6% ★, Simulation 14.7%, Indie 1.7%

  54. #54 Fun Hospital
    68% matchMixed64% of 614 reviews2018
    Dev: OrangesGame Technology Limited
    Windows · Mac
    Median: 1.2 hrsMean: 32.4 hrs≥1hr: 53%

    Build your own theme hospital! Here, you might meet patients with a lot of hair, or no hair; strange aliens, evil guy, super hero…

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  55. #55 Vital Signs: Emergency Department
    68% matchMixed57% of 75 reviews2020
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    Windows · Mac

    Play a doctor in Vital Signs: Emergency Department and challenge your medical knowledge to help treat a wide array of cases who come into the ER.

    Why similar: Medical Sim 67.9% ★, Time Management 20.7%, Simulation 10.9%, Singleplayer 0.5%

  56. #56 Nursing Simulator—Code Ube
    64% matchNo user reviews100% of 3 reviews2026
    Dev: Mobile Nursing LLC
    Windows · Mac · Linux

    When things aren't as they seem, nobody stands against fate but one nurse. Play as Karen—a nurse who saves lives and kicks butt! Complete tasks, give meds, and document assessments. But when night comes, beware of those who try to steer you away from what's right.

    Why similar: Medical Sim 72.5% ★, Simulation 26%, Indie 1%, Singleplayer 0.6%

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Games Like No Emergency: Pestilence

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