
The city is drowning in Plague. Panic, hunger, and fear are tearing it apart. You are the last one who can change its fate: heal it, hold it back from collapse… or drive it to ruin with your own hands!
60+ similar titles based on shared tags and player behavior. Themes include Simulation, Medical Sim, Outbreak Sim, Singleplayer.

The city is drowning in Plague. Panic, hunger, and fear are tearing it apart. You are the last one who can change its fate: heal it, hold it back from collapse… or drive it to ruin with your own hands!

The Book of Plagues 2
False Death has come to Grizmar. The plague steals souls and turns bodies into soulless puppets, doomed to repeat the final hours of their lives forever. Can you survive as the city turns into a puppet theater?

Plague Doctor: Medieval Apothecary
In a city where death lingers in the air, you are the last one who can resist it. Put on the plague doctor’s mask and fight the plague before it reaches you.
False Death has come to Grizmar. The plague steals souls and turns bodies into soulless puppets, doomed to repeat the final hours of their lives forever. Can you survive as the city turns into a puppet theater?
Why similar: Outbreak Sim 34.5% ★, Medical Sim 32% ★, Idler 10.3%, Dark Humor 7.4%, Choices Matter 4.9%
In a city where death lingers in the air, you are the last one who can resist it. Put on the plague doctor’s mask and fight the plague before it reaches you.
Why similar: Medical Sim 45% ★, Outbreak Sim 38.7% ★, Medieval 7.7%, Simulation 5.2%, Atmospheric 2.3%
A top-down plague simulation RPG set in a living medieval tapestry. Play the last apothecary in a dying town treating the sick, containing the outbreak, and navigating the politics of factions who'd sooner see you burn.
Why similar: Medical Sim 47.8% ★, Outbreak Sim 28.6% ★, Medieval 10.6%, Stylized 4.9%, Multiple Endings 3.7%
Save Us, Doctor Faust! is an immersive medieval doctor simulator where you diagnose diseases, study medicine, and craft remedies from raw ingredients. Examine your patients, grind and distill ingredients, experiment with recipes — and remember: one mistake could cost a life.
Why similar: Medical Sim 45.1% ★, Outbreak Sim 31.8% ★, Medieval 7.2%, Simulation 3.9%, Multiple Endings 3.2%
No Emergency: Pestilence plunges players into the epicenter of a mysterious epidemic, where every arriving patient could be carrying a mutating pathogen, and a single mistake in a prescription turns the cure into poison.
Why similar: Medical Sim 49.3% ★, Outbreak Sim 42% ★, Simulation 6.3%, Atmospheric 2.3%, Singleplayer 0.1%
Live the life of a rookie paramedic through frantic minigame action and a wild, funny story. Juggle waves of patients with a battle-like triage system; master dozens of treatment minigames; and win the city's recognition from the rival fire department!
Why similar: Medical Sim 54.6% ★, Visual Novel 12.5%, Arcade 9.8%, Simulation 7.7%, Funny 5.2%
Have you ever wanted to be a psychiatrist? Now you can! Be a shrink for 14 days. Meet 14 patients with unique story of their lives. Diagnosis, treatment, chosen dialogues have impact on history of patients. The choice is yours.
Why similar: Medical Sim 32.8% ★, Outbreak Sim 30.9% ★, Dark Humor 14%, Funny 5.9%, Choices Matter 5%
Amputations, bloodletting, alchemy - all of which seem unthinkable today - were the treatment options that medieval doctors revered. You must face challenges one after another and experience gains and losses in the course of your constant adventures
Why similar: Medical Sim 48.7% ★, Medieval 11.3%, Dark Humor 10.6%, Idler 8.8%, Multiple Endings 6%
《中国战疫》是一款科普防疫知识的模拟经营类游戏,玩家将临危受命地前往不同地区进行疫情控制,展示中国防疫的成功经验,最终达成疫情控制和经济稳定的双赢。
Why similar: Medical Sim 42.7% ★, Outbreak Sim 39.9% ★, Idler 11.7%, Simulation 3.2%, Funny 2.3%
In the event of a global pandemic, would your first priority be preserving lives or saving the economy?
Why similar: Outbreak Sim 48.2% ★, Medical Sim 43.7% ★, Simulation 4.4%, 2D 3.3%, Singleplayer 0.5%
Examine and test patients for common and novel infections using sophisticated medical instrumentation and disinfection procedures. All infected patients must be sent to the isolation ward for further evaluation or treatment. Rumors of mysterious diseases and human experimentation are unconfirmed.
Why similar: Outbreak Sim 54.5% ★, Medical Sim 31.1% ★, Simulation 5.9%, Choices Matter 5.5%, 2D 2.2%
Rescue Operations Simulator is a game where you play the role of USAR (Urban Search and Rescue) member and a team leader. You will arrange and execute rescue operations from real life catastrophic events that shocked and changed the whole world.
Why similar: Medical Sim 44.4% ★, Outbreak Sim 43.4% ★, Simulation 4.5%, Emotional 4.1%, Atmospheric 2.2%
Running an international organization called the Global Quarantine Bureau, dealing with pandemics and public health issues worldwide, while also ensuring increasing revenue and personal enrichment.
Why similar: Medical Sim 41% ★, Outbreak Sim 35% ★, Idler 13.7%, Dark Humor 4.5%, Simulation 3.4%
You inherit your father’s tavern in a small, isolated region.By day, life seems ordinaryBut when night falls, someone always knocks on your door.
Why similar: Outbreak Sim 51.8% ★, Medieval 13.4%, Visual Novel 11%, Multiple Endings 6.8%, Choices Matter 5.5%
When your airplane enters a massive storm, you aren’t a passenger anymore. You are a survivor. Trapped at 35,000 feet, you need to keep a cool head and act fast to live through the crisis. Can you make it to a happy landing?
Why similar: Medical Sim 47.2% ★, Outbreak Sim 45.4% ★, Simulation 7.2%, Singleplayer 0.2%
In Until The End, you play as Zoe, a young nurse who has just graduated. At the Montagne Institute, you will help her make the best decisions for the well-being of her patients in a palliative care unit.
Why similar: Medical Sim 52.1% ★, Visual Novel 11.1%, Choices Matter 7.6%, Dark Humor 6.2%, Emotional 5.4%
A satirical mental hospital survival simulator: control four unstable characters, craft from junk, forge dubious alliances, communicate with patients and staff, and choose between a quiet life in a ward, a riot, or a risky escape to freedom.
Why similar: Medical Sim 70.7% ★, Visual Novel 12.9%, Choices Matter 4.9%, Simulation 4.5%, Story Rich 3.9%
Fight ever-mutating bacteria and viruses, collect gene modules from fallen pathogens, evolve and strengthen your immune system, unlock a variety of medical interventions, and create powerful synergistic builds to survive an ever-escalating infection.
Why similar: Medical Sim 47.3% ★, Outbreak Sim 47.1% ★, 2D 2.5%, Simulation 2.2%, Adventure 0.8%
Bio Inc.: Redemption is a realistic simulation and strategy game in which you make life or death decisions. Create a deadly illness to infect and torment your victim or play as the head of a medical team and hopefully find a cure to save your human patient. Will you be the plague or preserve humanity?
Why similar: Medical Sim 51.5% ★, Outbreak Sim 41.9% ★, Simulation 3.4%, Atmospheric 2.8%, Singleplayer 0.4%
You are an apprentice of a traditional Chinese medicine herbalist in South Village. Your task is deceptively simple: Examine the pulse, ask about the symptoms and verify the identity of villagers and outsiders to expose the hidden "false people" from the diagnostic details.
Why similar: Medical Sim 46.4% ★, Outbreak Sim 45.2% ★, Stylized 4%, 2D 2.6%, Simulation 1.4%
“Hero Hospital” is a classic hospital management game: send in undercover agents and fake patient brokers, unleash dogs to cause crashes and chaos, dump trash and throw bombs, and even head into outbreak zones to fight viruses. The gameplay can be expanded endlessly.
Why similar: Medical Sim 53% ★, Outbreak Sim 44.3% ★, Simulation 2.6%
A 2D, veterinarian horror game. In this game, select the appropriate treatment and treat patients with topical products injections, surgeries. Treat patients over the course of 7 days, using the in-game computer to research the best treatment option.
Why similar: Medical Sim 71.7% ★, Multiple Endings 8.6%, Choices Matter 7.9%, Dark 4.7%, Simulation 4.1%
A young Plague Doctor, only to learn that the Academy sent to a small village, which, like the whole country is gripped by plague
Why similar: Medical Sim 42.1% ★, Outbreak Sim 39% ★, Medieval 9.6%, Choices Matter 4.7%, Simulation 2.4%
You run the only pharmacy in a rural town. Each face at the counter is the same, each ailment slightly different. Provide Care - Follow Our Rules - Stay Safe.
Why similar: Medical Sim 65.3% ★, Dark Humor 15.1%, Simulation 6.9%, Multiple Endings 6.4%, Stylized 5.9%
Patient Zero: Plague Idle is an idle / incremental outbreak builder where you create the perfect pathogen through mutation trees, global infection, long-term upgrades, and new pathogen unlocks. Turn the world into your lab.
Why similar: Outbreak Sim 45.2% ★, Medical Sim 27% ★, Idler 17.7%, Simulation 3.9%, 2D 3.1%
Scalpel, Please! is a ridiculous medical simulator where you assist a blindfolded surgeon. Provide tools, talk to him, and give your full support. But be careful: he’ll remember everything you do and react accordingly. Will you manage to keep your job?
Why similar: Medical Sim 65.8% ★, Dark Humor 12.1%, Simulation 7.8%, Funny 6.5%, Multiple Endings 4.2%
Rise from peasant dentist to royal healer in this quirky medieval dental simulation RPG. Treat patients, upgrade tools, improve your clinic, expand your knowledge, and restore Princess Penelope’s legendarily awful smile, all while facing sabotage from a jealous prince.
Why similar: Medical Sim 65.1% ★, Medieval 13.5%, Funny 8.1%, Multiple Endings 5.3%, Simulation 4.7%
You are the king. Petitioners bring tales of theft, betrayal, and ambition to your throne. Listen to their pleas, issue your decrees, and watch stability tip, shaping a kingdom of grudges, loyalty, and consequence.
Why similar: Medical Sim 55.5% ★, Medieval 13.7%, Visual Novel 9.1%, Choices Matter 6.6%, Funny 6.2%
An antidote shop simulator in Paris. Who will you save: your son, who cynically kills unwanted people, or a mad fanatic who poisons people for the sake of "rebirth"?
Why similar: Medical Sim 57.4% ★, Choices Matter 8%, Visual Novel 7.5%, Stylized 6.2%, Simulation 4.7%
Surgeon Simulator VR: Meet the Medic – be the Medic and operate on the Heavy in this free and exclusive teaser for the HTC Vive!
Why similar: Medical Sim 91.4% ★, Simulation 5%, Funny 3.6%
You think you’re healthy? There’re no healthy people — just those who haven’t been checked enough. And you definitely have problems. Try this pill. And, by the way, that’ll be five gold coins from you. A simulator of a rural psychiatrist who badly needs money.
Why similar: Medical Sim 45.3% ★, Multiple Endings 15%, Visual Novel 10.8%, Dark Humor 9%, Simulation 8.7%
You work the night shift inside a small aid booth. People arrive at your window asking for help. Food. Water. Medicine. Sometimes… things that don’t belong in a donation box. Every box you prepare makes the night worse.
Why similar: Outbreak Sim 67.3% ★, Choices Matter 9.5%, Multiple Endings 9.1%, Simulation 5.1%, Story Rich 4.6%
Awaken the incompetent doctor within you! Diagnose strange patients, examine their absurd symptoms… and prescribe treatments that could change their lives… or cut them short. Your actions will have consequences.
Why similar: Medical Sim 58.4% ★, Multiple Endings 11.1%, Choices Matter 10%, Dark Humor 7.9%, Simulation 4.3%
Manage the night shift of an ER during the apocalypse, solo or with friends online: Diagnose patients. Design and grow your hospital, and defend against the undead while treating the living. If you're a creator, connect the game to Twitch and make the audience your patients for even more fun!
Why similar: Medical Sim 43.3% ★, Outbreak Sim 38.3% ★, Dark Humor 12.6%, Simulation 3%, Atmospheric 2.8%
The long awaited sequel to "Heart's Medicine - Time to Heal". An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring doctor at Little Creek Hospital!
Why similar: Medical Sim 86.6% ★, Simulation 7.5%, Story Rich 3%, Adventure 2.9%
Build and manage your very own Supermarket and make it success, with good offers and best selected products. Attract more customers with an aggressive strategy and grow to become the best Supermarket in town.
Why similar: Medical Sim 49.3% ★, Outbreak Sim 38.6% ★, Simulation 7.7%, Funny 4.2%, Singleplayer 0.2%
Sculpt a tiny pixel world, seed it with life, and watch civilizations rise on their own. Kingdoms war, trade, and crown kings; dynasties fall to rebellion; whole ages turn. A cozy god-game sandbox where the story isn't scripted — it's discovered. No goals, no clock. Just a tiny world that lives.
Why similar: Medical Sim 40.9% ★, Outbreak Sim 36.3% ★, Idler 13.2%, Choices Matter 4.6%, Story Rich 2.9%
PSY in Apocalypse는 사실적인 2D 정신과 어드벤처 게임입니다. 여러분은 게임 속에서 정신과 의사가 되어 환자들을 직접 치료하게 됩니다. 포스트 아포칼립스 세계를 의사의 관점이라는 다소 새로운 시각으로 이야기를 풀어나가게 됩니다.
Why similar: Medical Sim 77.5% ★, Story Rich 7.4%, Atmospheric 4.7%, 2D 4.4%, Simulation 3.2%
Get ready to test your vet skills in Dr. Cares - Amy's Pet Clinic!
Why similar: Medical Sim 87.6% ★, Simulation 9.1%, Adventure 3.3%
Nano Fighter Anti Disease is a flight action game. Controlling a nanoscale fighter, flies over the acid sea of digestive system, passes through the scarred inflammatory lesions, launch a fierce attack towards various pathogens with medicine ammos and biological missiles.
Why similar: Medical Sim 51.5% ★, Outbreak Sim 45.6% ★, Simulation 2.6%, Singleplayer 0.3%
Welcome to Elixir, a 2D strategic puzzle experience. Become an ancient alchemist with a mysterious past to unlock. Explore & find lost souls who need your help. Uncover Elixirs and experiment on them, and yourself. Embark on a dark journey to solve puzzles, unlock recipes and unearth hidden secrets.
Why similar: Medical Sim 60.8% ★, Medieval 13.6%, Multiple Endings 7.9%, Stylized 4.3%, Simulation 3.4%
Here is a fun simulator of passing a medical examination in the Chelyabinsk clinic with realistic graphics and interesting gameplay! Take the coronavirus test! Collect as many virtual health points as you can, but remember ... this is just a game!
Why similar: Medical Sim 92% ★, Simulation 8%
Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.
Why similar: Medical Sim 36.6% ★, Outbreak Sim 33.3% ★, Dark Humor 11.5%, Story Rich 5.4%, Funny 5.3%
A medical simulation where you examine and treat magical girls injured in kaiju disasters. With limited hospital beds and stamina, decide who to accept, who to refuse, and which treatment to choose.
Why similar: Medical Sim 62.4% ★, Visual Novel 12%, Multiple Endings 8.3%, Story Rich 5.3%, Dark 4.1%
An absurd comedy visual novel about a scientist dinosaur trying to stop a meteor while politicians, media stars, and rich lizards compete to be catastrophically stupid.
Why similar: Outbreak Sim 68.3% ★, Visual Novel 16.8%, Multiple Endings 8.2%, Choices Matter 6.3%, Singleplayer 0.5%
Reanimation inc is a completely realistic simulation - real urgent conditions and diseases, real protocols of care used in an ambulance, realistic simulation of the body! Do you like realistic games about medicine and simulators, games you need to think about? You 'll be happy!
Why similar: Medical Sim 91.7% ★, Simulation 8.3%
A medical idle game with real hospital depth. Treat patients, hire staff, and unlock departments from the ED to the ICU — then watch your hospital run itself while you sleep.
Why similar: Medical Sim 60.6% ★, Idler 28.8%, Simulation 5.2%, Atmospheric 2.8%, 2D 2.2%
Collect a 3D puzzle, transferring things to the right places to create a beautiful house.
Why similar: Medical Sim 48.5% ★, Outbreak Sim 43.3% ★, Medieval 8.2%
You don't cure patients; you decide their fate. In this grim medical sim, review records and face impossible bioethical dilemmas. Consult the Medical Bible and choose who gets the bed. Every signature impacts your Ethics, Reputation, and Legal Risk. In a broken system, mercy is a dangerous luxury.
Why similar: Medical Sim 59.6% ★, Visual Novel 13%, Emotional 6.6%, Simulation 5.2%, Dark 3.9%
A story-driven survival visual novel inspired by SCP-610. Face a flesh-spreading outbreak, make brutal moral choices, protect the people you can’t let go of, and uncover the terrifying truth behind the disease.
Why similar: Outbreak Sim 52.8% ★, Visual Novel 17.7%, Emotional 10.6%, 2D 6.4%, Dark 6%
40 Days is a special strategy simulation game related to infectious diseases spread all over the city. You, as ahead of the quarantine department, have been given full authority and manpower to contain the city, deal with different parties, virus in the city and most importantly find out the cure.
Why similar: Outbreak Sim 94.5% ★, Simulation 5.5%
Witness Sickness is a 4–8 player social deduction horror game. Complete cooperative tasks, watch the crew, obey real Sickness commands, ignore fake orders, and find the infected before the station falls apart.
Why similar: Outbreak Sim 51.5% ★, Idler 19.9%, Arcade 9.7%, Multiple Endings 4.8%, Atmospheric 3.7%
Will you be able to infect all devices of the world? «Trojan Inc.» - simulator, which will involve you in a world of computer viruses and trojans.
Why similar: Outbreak Sim 93.7% ★, Simulation 6.3%
An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring surgeon at Little Creek Hospital!
Why similar: Medical Sim 88.6% ★, Simulation 5.2%, Story Rich 3.9%, Adventure 1.9%, Singleplayer 0.4%
Concepts are bombs. Association is death. An cult-like anti-utopian psychological horror puzzle game. The subject has a concept bomb implanted in brain. If a subject thinks of the [Fuse Word], their head detonates. You, as the "cognitive bomb defuser", dismantling the deadly "brain bomb".
Why similar: Medical Sim 80.1% ★, Dark Humor 12.4%, Simulation 5.2%, Atmospheric 2.1%, Singleplayer 0.3%
Operation Pill is the story of a small and brave pill that gets into your body and saves it from pathogenic bacteria. Arm yourself with an electrostatic shield and a germicidal cannon and save your body!
Why similar: Medical Sim 66.1% ★, Idler 24.3%, Arcade 6.4%, Simulation 2.7%, Singleplayer 0.5%