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Games Like The Book of Plagues

60+ similar titles based on shared tags and player behavior. Themes include Simulation, Medical Sim, Outbreak Sim, Singleplayer.

Similar Games

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  1. #1 The Book of Plagues 2
    97% matchNo user reviews2027
    Dev: DiaMMax Games
    Windows

    False Death has come to Grizmar. The plague steals souls and turns bodies into soulless puppets, doomed to repeat the final hours of their lives forever. Can you survive as the city turns into a puppet theater?

    Why similar: Outbreak Sim 34.6% ★, Medical Sim 32.3% ★, Idler 10%, Dark Humor 7.4%, Choices Matter 4.9%

  2. #2 Plague Doctor: Medieval Apothecary
    96% matchNo user reviews
    Dev: Immersion Interactive
    Windows

    In a city where death lingers in the air, you are the last one who can resist it. Put on the plague doctor’s mask and fight the plague before it reaches you.

    Why similar: Medical Sim 45.2% ★, Outbreak Sim 38.6% ★, Medieval 7.7%, Simulation 5.2%, Atmospheric 2.3%

  3. #3 Morbus: The Burden Of The Apothecary
    96% matchNo user reviews
    Dev: Viktor PekarPub: Introverse Interactive
    Windows · Linux

    A top-down plague simulation RPG set in a living medieval tapestry. Play the last apothecary in a dying town treating the sick, containing the outbreak, and navigating the politics of factions who'd sooner see you burn.

    Why similar: Medical Sim 48% ★, Outbreak Sim 28.6% ★, Medieval 10.5%, Stylized 4.8%, Multiple Endings 3.7%

  4. #4 Save Us, Doctor Faust!
    95% matchNo user reviews2027
    Dev: MIWAVV GAMES
    Windows

    Save Us, Doctor Faust! is an immersive medieval doctor simulator where you diagnose diseases, study medicine, and craft remedies from raw ingredients. Examine your patients, grind and distill ingredients, experiment with recipes — and remember: one mistake could cost a life.

    Why similar: Medical Sim 43.4% ★, Outbreak Sim 30.9% ★, Medieval 8.1%, Multiple Endings 4.2%, Choices Matter 3.8%

  5. #5 No Emergency: Pestilence
    94% matchNo user reviews2026
    Dev: 20 July
    Windows

    No Emergency: Pestilence plunges players into the epicenter of a mysterious epidemic, where every arriving patient could be carrying a mutating pathogen, and a single mistake in a prescription turns the cure into poison.

    Why similar: Medical Sim 49.5% ★, Outbreak Sim 41.9% ★, Simulation 6.2%, Atmospheric 2.3%, Singleplayer 0.1%

  6. #6 Neo Harbor Rescue Squad
    93% matchMostly Positive77% of 13 reviews2024
    Dev: BancyCo
    Windows

    Live the life of a rookie paramedic through frantic minigame action and a wild, funny story. Juggle waves of patients with a battle-like triage system; master dozens of treatment minigames; and win the city's recognition from the rival fire department!

    Why similar: Medical Sim 54.8% ★, Visual Novel 12.6%, Arcade 9.8%, Simulation 7.6%, Funny 5.2%

  7. #7 Psychiatrist Simulator
    94% matchMostly Negative40% of 129 reviews2018
    Dev: Eathrabaria
    Windows
    Median: 12 minMean: 18.5 hrs≥1hr: 34%

    Have you ever wanted to be a psychiatrist? Now you can! Be a shrink for 14 days. Meet 14 patients with unique story of their lives. Diagnosis, treatment, chosen dialogues have impact on history of patients. The choice is yours.

    Why similar: Medical Sim 33% ★, Outbreak Sim 30.8% ★, Dark Humor 13.9%, Funny 5.9%, Choices Matter 5%

  8. #8 Dr. Chatelet: Faith 神医
    92% matchVery Positive85% of 132 reviews2022
    Dev: MuccyGames
    Windows · Mac

    Amputations, bloodletting, alchemy - all of which seem unthinkable today - were the treatment options that medieval doctors revered. You must face challenges one after another and experience gains and losses in the course of your constant adventures

    Why similar: Medical Sim 49% ★, Medieval 11.4%, Dark Humor 10.5%, Idler 8.6%, Multiple Endings 6%

  9. #9 中国战疫
    91% matchMostly Positive75% of 72 reviews2022
    Dev: 不吃蛋黄
    Windows

    《中国战疫》是一款科普防疫知识的模拟经营类游戏,玩家将临危受命地前往不同地区进行疫情控制,展示中国防疫的成功经验,最终达成疫情控制和经济稳定的双赢。

    Why similar: Medical Sim 42.9% ★, Outbreak Sim 40% ★, Idler 11.4%, Simulation 3.2%, Funny 2.3%

  10. #10 Pandemic Crisis
    91% match9 user reviews100% of 9 reviews2020
    Dev: Thor Gaming
    Windows

    In the event of a global pandemic, would your first priority be preserving lives or saving the economy?

    Why similar: Outbreak Sim 48.1% ★, Medical Sim 43.9% ★, Simulation 4.3%, 2D 3.3%, Singleplayer 0.5%

  11. #11 Symptoms of Infection
    89% matchNo user reviews91% of 69 reviews2026
    Dev: ORB Research & Broadcasting
    Windows · Linux

    Examine and test patients for common and novel infections using sophisticated medical instrumentation. Isolate and treat infected patients. Discover the wonders, mysteries, and horrors of medical science. Rumors of mysterious diseases and human experimentation are unconfirmed.

    Why similar: Outbreak Sim 54.5% ★, Medical Sim 31.2% ★, Simulation 5.8%, Choices Matter 5.5%, 2D 2.2%

  12. #12 Rescue Operations Simulator
    89% matchNo user reviews
    Dev: Monuments Games
    Windows

    Rescue Operations Simulator is a game where you play the role of USAR (Urban Search and Rescue) member and a team leader. You will arrange and execute rescue operations from real life catastrophic events that shocked and changed the whole world.

    Why similar: Medical Sim 44.6% ★, Outbreak Sim 43.3% ★, Simulation 4.5%, Emotional 4.2%, Atmospheric 2.2%

  13. #13 The Long Winter: I Am Not an Animal
    88% match7 user reviews29% of 7 reviews2026
    Dev: Playnova
    Windows

    You inherit your father’s tavern in a small, isolated region.By day, life seems ordinaryBut when night falls, someone always knocks on your door.

    Why similar: Outbreak Sim 51.7% ★, Medieval 13.3%, Visual Novel 11.1%, Multiple Endings 6.8%, Choices Matter 5.4%

  14. #14 GlobalQuarantine
    87% match7 user reviews43% of 7 reviews2025
    Dev: ValarFerys
    Windows

    Running an international organization called the Global Quarantine Bureau, dealing with pandemics and public health issues worldwide, while also ensuring increasing revenue and personal enrichment.

    Why similar: Medical Sim 41.3% ★, Outbreak Sim 35% ★, Idler 13.4%, Dark Humor 4.5%, Simulation 3.4%

  15. #15 Turbulence - Airplane Survival Simulator
    86% matchNo user reviews
    Dev: True GamesPub: Idea Labs
    Windows

    When your airplane enters a massive storm, you aren’t a passenger anymore. You are a survivor. Trapped at 35,000 feet, you need to keep a cool head and act fast to live through the crisis. Can you make it to a happy landing?

    Why similar: Medical Sim 47.3% ★, Outbreak Sim 45.3% ★, Simulation 7.1%, Singleplayer 0.2%

  16. #16 Until The End
    86% matchMixed50% of 10 reviews2022
    Dev: Red Sorel Games
    Windows

    In Until The End, you play as Zoe, a young nurse who has just graduated. At the Montagne Institute, you will help her make the best decisions for the well-being of her patients in a palliative care unit.

    Why similar: Medical Sim 52.2% ★, Visual Novel 11.1%, Choices Matter 7.5%, Dark Humor 6.2%, Emotional 5.4%

  17. #17 Germ Swarm: Evolution & Mutation
    84% matchNo user reviews
    Dev: Interlink Game Studio
    Windows · Mac

    Fight ever-mutating bacteria and viruses, collect gene modules from fallen pathogens, evolve and strengthen your immune system, unlock a variety of medical interventions, and create powerful synergistic builds to survive an ever-escalating infection.

    Why similar: Medical Sim 47.5% ★, Outbreak Sim 47% ★, 2D 2.5%, Simulation 2.2%, Adventure 0.8%

  18. #18 Bio Inc. Redemption
    85% matchVery Positive88% of 3,261 reviews2018
    Dev: DryGin Studios
    Windows
    Median: 2.4 hrsMean: 5.9 hrs≥1hr: 72%

    Bio Inc.: Redemption is a realistic simulation and strategy game in which you make life or death decisions. Create a deadly illness to infect and torment your victim or play as the head of a medical team and hopefully find a cure to save your human patient. Will you be the plague or preserve humanity?

    Why similar: Medical Sim 51.7% ★, Outbreak Sim 41.8% ★, Simulation 3.3%, Atmospheric 2.7%, Singleplayer 0.4%

  19. #19 Psyhonds
    83% matchMostly Positive70% of 10 reviews2026
    Dev: Meriteri GamesPub: Terrabyte Games
    Windows

    A satirical mental hospital survival simulator: control four unstable characters, craft from junk, forge dubious alliances, communicate with patients and staff, and choose between a quiet life in a ward, a riot, or a risky escape to freedom.

    Why similar: Medical Sim 70.8% ★, Visual Novel 12.9%, Choices Matter 4.9%, Simulation 4.4%, Story Rich 3.9%

  20. #20 Bio Inc. Classic
    84% matchNo user reviews2026
    Dev: DryGin Studios
    Windows

    Relive the original Bio Inc. experience, rebuilt from the ground up for PC to celebrate its 15th anniversary. Develop deadly diseases, cripple your victim’s body, and determine their ultimate fate in this biomedical strategy simulator.

    Why similar: Outbreak Sim 68.2% ★, Idler 13.4%, Simulation 9.6%, Atmospheric 4.1%, 2D 4.1%

  21. #21 Before I Turn: Survival Auto Battler
    81% matchNo user reviews2026
    Dev: fragilentPub: Fragilent
    Windows

    You've been bitten. Hours before you turn. All you have left: a clock running out and a deserted hospital lab. Identify the virus, synthesize your antiviral, and test it. But every win teaches it to resist you. Before I Turn blends survival, auto battler and simulation into one experience.

    Why similar: Medical Sim 48.9% ★, Outbreak Sim 47.1% ★, Simulation 3.1%, Atmospheric 0.9%

  22. #22 The Attending
    81% matchNo user reviews
    Dev: Abreu Data Works
    Windows

    You are the attending physician on the night shift. Your doctors work the cases — and report what they believe, not what's true. Read their workups, catch the miss before it walks out the door, and spend your trust where it counts. One night. One board. Everyone's yours.

    Why similar: Medical Sim 76.2% ★, Choices Matter 8%, Story Rich 6.5%, Simulation 6.4%, Atmospheric 2.5%

  23. #23 英雄荣光医院
    79% matchPositive100% of 11 reviews2026
    Dev: Areas RPub: PeopleFirstAI
    Windows

    “Hero Hospital” is a classic hospital management game: send in undercover agents and fake patient brokers, unleash dogs to cause crashes and chaos, dump trash and throw bombs, and even head into outbreak zones to fight viruses. The gameplay can be expanded endlessly.

    Why similar: Medical Sim 53.2% ★, Outbreak Sim 44.2% ★, Simulation 2.6%

  24. #24 Wrist Catcher-寸关
    80% match3 user reviews0% of 3 reviews2025
    Dev: 昆吾灌灌KWGG
    Windows

    You are an apprentice of a traditional Chinese medicine herbalist in South Village. Your task is deceptively simple: Examine the pulse, ask about the symptoms and verify the identity of villagers and outsiders to expose the hidden "false people" from the diagnostic details.

    Why similar: Medical Sim 46.6% ★, Outbreak Sim 45.2% ★, Stylized 4%, 2D 2.6%, Simulation 1.4%

  25. #25 Pestis
    82% matchMostly Positive70% of 109 reviews2018
    Dev: DIEDEMOR STUDIO GAMESPub: Laush Studio
    Windows
    Median: 12 minMean: 3.0 hrs≥1hr: 33%

    A young Plague Doctor, only to learn that the Academy sent to a small village, which, like the whole country is gripped by plague

    Why similar: Medical Sim 42.2% ★, Outbreak Sim 38.9% ★, Medieval 9.6%, Choices Matter 4.7%, Simulation 2.4%

  26. #26 Opawration!
    79% matchNo user reviews
    Dev: chinchingames
    Windows

    A 2D, veterinarian horror game. In this game, select the appropriate treatment and treat patients with topical products injections, surgeries. Treat patients over the course of 7 days, using the in-game computer to research the best treatment option.

    Why similar: Medical Sim 71.9% ★, Multiple Endings 8.5%, Choices Matter 7.8%, Dark 4.7%, Simulation 4%

  27. #27 Epi Derick
    78% matchPositive80% of 10 reviews2025
    Dev: Fireslug Studios
    Windows

    You run the only pharmacy in a rural town. Each face at the counter is the same, each ailment slightly different. Provide Care - Follow Our Rules - Stay Safe.

    Why similar: Medical Sim 65.5% ★, Dark Humor 15%, Simulation 6.8%, Multiple Endings 6.5%, Stylized 5.8%

  28. #28 Patient Zero: Plague Idle
    78% matchNo user reviews
    Dev: Game GangstersPub: Brightika, Inc.
    Windows

    Patient Zero: Plague Idle is an idle / incremental outbreak builder where you create the perfect pathogen through mutation trees, global infection, long-term upgrades, and new pathogen unlocks. Turn the world into your lab.

    Why similar: Outbreak Sim 45.4% ★, Medical Sim 27.3% ★, Idler 17.3%, Simulation 3.9%, 2D 3.1%

  29. #29 Scalpel, Please!
    76% matchNo user reviews
    Dev: WoolCat Games
    Windows

    Scalpel, Please! is a ridiculous medical simulator where you assist a blindfolded surgeon. Provide tools, talk to him, and give your full support. But be careful: he’ll remember everything you do and react accordingly. Will you manage to keep your job?

    Why similar: Medical Sim 66% ★, Dark Humor 12%, Simulation 7.7%, Funny 6.5%, Multiple Endings 4.2%

  30. #30 Royal Dental
    75% match3 user reviews100% of 3 reviews2026
    Dev: Visionaire Labs
    Windows

    Rise from peasant dentist to royal healer in this quirky medieval dental simulation RPG. Treat patients, upgrade tools, improve your clinic, expand your knowledge, and restore Princess Penelope’s legendarily awful smile, all while facing sabotage from a jealous prince.

    Why similar: Medical Sim 65.3% ★, Medieval 13.5%, Funny 8.1%, Multiple Endings 5.3%, Simulation 4.7%

  31. #31 Fool's Court
    75% match3 user reviews67% of 3 reviews2026
    Dev: Veras Studios
    Windows

    You are the king. Petitioners bring tales of theft, betrayal, and ambition to your throne. Listen to their pleas, issue your decrees, and watch stability tip, shaping a kingdom of grudges, loyalty, and consequence.

    Why similar: Medical Sim 55.6% ★, Medieval 13.6%, Visual Novel 9.1%, Choices Matter 6.5%, Funny 6.1%

  32. #32 Antidote to despair
    74% match9 user reviews89% of 9 reviews2026
    Dev: Gamet
    Windows

    An antidote shop simulator in Paris. Who will you save: your son, who cynically kills unwanted people, or a mad fanatic who poisons people for the sake of "rebirth"?

    Why similar: Medical Sim 57.5% ★, Choices Matter 8%, Visual Novel 7.6%, Stylized 6.1%, Simulation 4.7%

  33. #33 Tell me your Problem
    74% matchNo user reviews
    Dev: Alzakprod.Games
    Windows · Mac

    You think you’re healthy? There’re no healthy people — just those who haven’t been checked enough. And you definitely have problems. Try this pill. And, by the way, that’ll be five gold coins from you. A simulator of a rural psychiatrist who badly needs money.

    Why similar: Medical Sim 45.5% ★, Multiple Endings 15%, Visual Novel 10.8%, Dark Humor 8.9%, Simulation 8.6%

  34. #34 Surgeon Simulator VR: Meet The Medic
    76% matchMostly Positive77% of 598 reviews2016
    Dev: Bossa Studios
    Windows
    Median: 18 minMean: 1.6 hrs≥1hr: 14%

    Surgeon Simulator VR: Meet the Medic – be the Medic and operate on the Heavy in this free and exclusive teaser for the HTC Vive!

    Why similar: Medical Sim 91.4% ★, Simulation 4.9%, Funny 3.7%

  35. #35 Homeless Kiosk Simulator
    73% matchNo user reviews
    Dev: HKS
    Windows

    You work the night shift inside a small aid booth. People arrive at your window asking for help. Food. Water. Medicine. Sometimes… things that don’t belong in a donation box. Every box you prepare makes the night worse.

    Why similar: Outbreak Sim 67.3% ★, Choices Matter 9.4%, Multiple Endings 9.1%, Simulation 5.1%, Story Rich 4.6%

  36. #36 CURE - A Hospital Simulator
    70% matchVery Positive88% of 1,000 reviews2025
    Dev: Sentinel Games
    Windows
    Median: 4.9 hrsMean: 10.1 hrs≥1hr: 87%

    Manage the night shift of an ER during the apocalypse, solo or with friends online: Diagnose patients. Design and grow your hospital, and defend against the undead while treating the living. If you're a creator, connect the game to Twitch and make the audience your patients for even more fun!

    Why similar: Medical Sim 43.5% ★, Outbreak Sim 38.2% ★, Dark Humor 12.5%, Simulation 3%, Atmospheric 2.8%

  37. #37 Galacticare
    71% matchVery Positive86% of 662 reviews2024
    Dev: Brightrock GamesPub: Mythwright
    Windows
    Median: 5.8 hrsMean: 12.5 hrs≥1hr: 93%

    Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.

    Why similar: Medical Sim 36.7% ★, Outbreak Sim 33.3% ★, Dark Humor 11.4%, Story Rich 5.5%, Funny 5.3%

  38. #38 Prescribe and Pray
    70% matchMostly Positive74% of 81 reviews2026
    Dev: Nuclear Rabbits
    Windows

    Awaken the incompetent doctor within you! Diagnose strange patients, examine their absurd symptoms… and prescribe treatments that could change their lives… or cut them short. Your actions will have consequences.

    Why similar: Medical Sim 58.6% ★, Multiple Endings 11.1%, Choices Matter 9.9%, Dark Humor 7.9%, Simulation 4.2%

  39. #39 Heart's Medicine - Hospital Heat
    73% matchVery Positive96% of 366 reviews2017
    Dev: Blue GiraffePub: GameHouse
    Windows · Mac
    Median: 5.1 hrsMean: 8.7 hrs≥1hr: 93%

    The long awaited sequel to "Heart's Medicine - Time to Heal". An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring doctor at Little Creek Hospital!

    Why similar: Medical Sim 86.7% ★, Simulation 7.4%, Story Rich 3%, Adventure 2.9%

  40. #40 Supermarket Maker
    71% matchNo user reviews
    Dev: El NanPub: La Blen
    Windows

    Build and manage your very own Supermarket and make it success, with good offers and best selected products. Attract more customers with an aggressive strategy and grow to become the best Supermarket in town.

    Why similar: Medical Sim 49.5% ★, Outbreak Sim 38.5% ★, Simulation 7.6%, Funny 4.2%, Singleplayer 0.2%

  41. #41 PSY in Apocalypse
    71% matchNo user reviews
    Dev: Quantum Strawberry
    Windows

    PSY in Apocalypse는 사실적인 2D 정신과 어드벤처 게임입니다. 여러분은 게임 속에서 정신과 의사가 되어 환자들을 직접 치료하게 됩니다. 포스트 아포칼립스 세계를 의사의 관점이라는 다소 새로운 시각으로 이야기를 풀어나가게 됩니다.

    Why similar: Medical Sim 77.6% ★, Story Rich 7.4%, Atmospheric 4.6%, 2D 4.4%, Simulation 3.2%

  42. #42 Dr. Cares - Amy's Pet Clinic
    73% matchMostly Positive79% of 77 reviews2018
    Dev: NitrealPub: GameHouse
    Windows · Mac

    Get ready to test your vet skills in Dr. Cares - Amy's Pet Clinic!

    Why similar: Medical Sim 87.7% ★, Simulation 9%, Adventure 3.4%

  43. #43 Elixir
    70% matchPositive93% of 44 reviews2024
    Dev: Moxu Projects
    Windows

    Welcome to Elixir, a 2D strategic puzzle experience. Become an ancient alchemist with a mysterious past to unlock. Explore & find lost souls who need your help. Uncover Elixirs and experiment on them, and yourself. Embark on a dark journey to solve puzzles, unlock recipes and unearth hidden secrets.

    Why similar: Medical Sim 61% ★, Medieval 13.5%, Multiple Endings 7.9%, Stylized 4.3%, Simulation 3.4%

  44. #44 Nano Fighter Anti Disease
    72% match9 user reviews89% of 9 reviews2021
    Dev: LBR games
    Windows

    Nano Fighter Anti Disease is a flight action game. Controlling a nanoscale fighter, flies over the acid sea of digestive system, passes through the scarred inflammatory lesions, launch a fierce attack towards various pathogens with medicine ammos and biological missiles.

    Why similar: Medical Sim 51.7% ★, Outbreak Sim 45.5% ★, Simulation 2.6%, Singleplayer 0.3%

  45. #45 Medical verdict
    72% matchMixed57% of 53 reviews2018
    Dev: Volokitin Andrey
    Windows

    Here is a fun simulator of passing a medical examination in the Chelyabinsk clinic with realistic graphics and interesting gameplay! Take the coronavirus test! Collect as many virtual health points as you can, but remember ... this is just a game!

    Why similar: Medical Sim 92.1% ★, Simulation 7.9%

  46. #46 Code Blue Idle
    68% match2 user reviews50% of 2 reviews2026
    Dev: Sulcus Games
    Windows

    A medical idle game with real hospital depth. Treat patients, hire staff, and unlock departments from the ED to the ICU — then watch your hospital run itself while you sleep.

    Why similar: Medical Sim 61.3% ★, Idler 28.2%, Simulation 5.2%, Atmospheric 2.8%, 2D 2.2%

  47. #47 Magical Girl ER
    68% matchNo user reviews2026
    Dev: noranuco
    Windows

    A medical simulation where you examine and treat magical girls injured in kaiju disasters. With limited hospital beds and stamina, decide who to accept, who to refuse, and which treatment to choose.

    Why similar: Medical Sim 62.2% ★, Visual Novel 12.2%, Multiple Endings 8.4%, Story Rich 5.3%, Dark 4.1%

  48. #48 Dino Goodbye
    66% match7 user reviews71% of 7 reviews2026
    Dev: SmogGames
    Windows

    An absurd comedy visual novel about a scientist dinosaur trying to stop a meteor while politicians, media stars, and rich lizards compete to be catastrophically stupid.

    Why similar: Outbreak Sim 68.2% ★, Visual Novel 16.9%, Multiple Endings 8.2%, Choices Matter 6.3%, Singleplayer 0.5%

  49. #49 Reanimation Inc.
    69% matchVery Positive81% of 134 reviews2019
    Dev: Dmitrii Lomakin
    Windows

    Reanimation inc is a completely realistic simulation - real urgent conditions and diseases, real protocols of care used in an ambulance, realistic simulation of the body! Do you like realistic games about medicine and simulators, games you need to think about? You 'll be happy!

    Why similar: Medical Sim 91.8% ★, Simulation 8.2%

  50. #50 EverBlock
    67% matchNo user reviews
    Dev: Sun Monster FxxL
    Windows

    EverBlock blends evolving blocks with bullet-hell survival. Choose six craft types, aim manually, dodge, and blink. Battle multiplying blocks, Bosses, and Demon Lords. Earn XP, gather materials, and build your Shelter to unlock craft and upgrades. Adapt and survive.

    Why similar: Outbreak Sim 54.4% ★, Bullet Hell 21.2%, Arcade 7.2%, Simulation 7%, 2D 2.8%

  51. #51 Dilemma
    65% matchPositive95% of 22 reviews2026
    Dev: DrAxelStudio
    Windows

    You don't cure patients; you decide their fate. In this grim medical sim, review records and face impossible bioethical dilemmas. Consult the Medical Bible and choose who gets the bed. Every signature impacts your Ethics, Reputation, and Legal Risk. In a broken system, mercy is a dangerous luxury.

    Why similar: Medical Sim 59.7% ★, Visual Novel 13%, Emotional 6.6%, Simulation 5.1%, Dark 3.9%

  52. #52 3D PUZZLE - Farm House
    68% matchMixed43% of 44 reviews2022
    Dev: AztechPub: Azerbaijan Technology
    Windows · Mac · Linux

    Collect a 3D puzzle, transferring things to the right places to create a beautiful house.

    Why similar: Medical Sim 48.7% ★, Outbreak Sim 43.2% ★, Medieval 8.1%

  53. #53 FLESHBREAK
    65% matchNo user reviews39% of 88 reviews2026
    Dev: Horubrain InteractivePub: Hexapede Engine
    Windows

    A story-driven survival visual novel inspired by SCP-610. Face a flesh-spreading outbreak, make brutal moral choices, protect the people you can’t let go of, and uncover the terrifying truth behind the disease.

    Why similar: Outbreak Sim 52.7% ★, Visual Novel 17.8%, Emotional 10.6%, 2D 6.4%, Dark 6%

  54. #54 40 Days [四十天]
    69% matchMixed54% of 13 reviews2017
    Dev: Black Phoenix Studio
    Windows · Mac

    40 Days is a special strategy simulation game related to infectious diseases spread all over the city. You, as ahead of the quarantine department, have been given full authority and manpower to contain the city, deal with different parties, virus in the city and most importantly find out the cure.

    Why similar: Outbreak Sim 94.5% ★, Simulation 5.5%

  55. #55 Witness Sickness
    66% matchNo user reviews
    Dev: a1rl3ss
    Windows

    Witness Sickness is a 4–8 player social deduction horror game. Complete cooperative tasks, watch the crew, obey real Sickness commands, ignore fake orders, and find the infected before the station falls apart.

    Why similar: Outbreak Sim 51.8% ★, Idler 19.5%, Arcade 9.8%, Multiple Endings 4.9%, Atmospheric 3.8%

  56. #56 Heart's Medicine - Time to Heal
    67% matchVery Positive94% of 884 reviews2016
    Dev: Blue GiraffePub: GameHouse
    Windows · Mac
    Median: 6.0 hrsMean: 12.2 hrs≥1hr: 92%

    An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring surgeon at Little Creek Hospital!

    Why similar: Medical Sim 88.6% ★, Simulation 5.1%, Story Rich 3.9%, Adventure 1.9%, Singleplayer 0.4%

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