- #1 Bacterium / 生命之旅
97% matchPositive84% of 49 reviews2018
Dev: Dragon Whisper GamePub: Zodiac Interactive
Windows
In the coming decades, a huge breakthrough in nano-medical technology will bring a new light to cure terminally ill patients. As a nano-robot operator, you will be involved in a battle between nanobots and diseases!
Why similar: Medical Sim 67.1% ★, Simulation 18.3%, Action 11.4%, Adventure 3.3%
- #2 Dr. Cares - Amy's Pet Clinic
96% matchMostly Positive79% of 75 reviews2018
Dev: NitrealPub: GameHouse
Windows · Mac
Get ready to test your vet skills in Dr. Cares - Amy's Pet Clinic!
Why similar: Medical Sim 74.1% ★, Simulation 22.1%, Adventure 3.8%
- #3 Surgeon Simulator VR: Meet The Medic
96% matchMostly Positive77% of 580 reviews2016
Dev: Bossa Studios
Windows
Median: 18 minMean: 1.7 hrs≥1hr: 14%
Surgeon Simulator VR: Meet the Medic – be the Medic and operate on the Heavy in this free and exclusive teaser for the HTC Vive!
Why similar: Medical Sim 79.8% ★, Simulation 12.5%, Action 5.2%, Funny 2.5%
- #4 Medical verdict
94% matchMixed57% of 53 reviews2018
Dev: Volokitin Andrey
Windows
Here is a fun simulator of passing a medical examination in the Chelyabinsk clinic with realistic graphics and interesting gameplay! Take the coronavirus test! Collect as many virtual health points as you can, but remember ... this is just a game!
Why similar: Medical Sim 79.9% ★, Simulation 20.1%
- #5 Heart's Medicine - Hospital Heat
93% matchVery Positive96% of 364 reviews2017
Dev: Blue GiraffePub: GameHouse
Windows · Mac
Median: 5.1 hrsMean: 8.7 hrs≥1hr: 93%
The long awaited sequel to "Heart's Medicine - Time to Heal". An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring doctor at Little Creek Hospital!
Why similar: Medical Sim 76.3% ★, Simulation 19%, Adventure 3.4%, Story Rich 1.2%
- #6 Reanimation Inc.
92% matchVery Positive84% of 129 reviews2019
Dev: Dmitrii Lomakin
Windows
Reanimation inc is a completely realistic simulation - real urgent conditions and diseases, real protocols of care used in an ambulance, realistic simulation of the body! Do you like realistic games about medicine and simulators, games you need to think about? You 'll be happy!
Why similar: Medical Sim 79.4% ★, Simulation 20.6%
- #7 Psyhonds
91% match5 user reviews80% of 5 reviews2026
Dev: Meriteri GamesPub: Terrabyte Games
Windows
A satirical mental hospital survival simulator: control four unstable characters, craft from junk, forge dubious alliances, communicate with patients and staff, and choose between a quiet life in a ward, a riot, or a risky escape to freedom.
Why similar: Medical Sim 67.3% ★, Visual Novel 14.9%, Simulation 12.2%, Choices Matter 3.5%, Story Rich 1.8%
- #8 Dr Greenstuff
91% matchVery Positive87% of 148 reviews2018
Dev: Black DiskettePub: Black Diskette Studio
Windows
Discover the life of Dr Greenstuff, grow marijuana, coca, make meth', drugs and more to keep your legal/illegal business running.
Why similar: Medical Sim 77.5% ★, Simulation 22.5%
- #9 First Steps in Learning about Childbirth
90% matchNo user reviews
Dev: エムテラス
Windows
An educational serious game where you experience the process of childbirth through story and interactive mini-games, developed with medical professionals.
Why similar: Medical Sim 48.9% ★, Simulation 21.5%, Visual Novel 15.7%, Anime 5.7%, Adventure 4.4%
- #10 On Call
89% match9 user reviews90% of 10 reviews2023
Dev: CelleC Games
Windows · Mac
On Call is a visual novel that takes you through a 3-day rotation at Merritt General Hospital. Build trust with your patients and their families to get them on the road to recovery. Manage your own stress while confronting these challenges or you may just crack under the pressure.
Why similar: Medical Sim 48.3% ★, Simulation 23.3%, Visual Novel 16.2%, Colorful 3.7%, Choices Matter 3.7%
- #11 Cutting Edge: Roots Of Mutation
89% matchNo user reviews2026
Dev: Wizbird Games LLC
Windows
Perform life-saving operations in this fast-paced surgery sim. As lizard surgeon Dr. Peri Maddock, you'll treat injuries, excise tumors, and hack corporate organs with speedy, surgical precision. The patient's life is in your claws!
Why similar: Medical Sim 59.7% ★, Visual Novel 12.2%, Simulation 11.3%, Action 7.1%, Cartoony 5.2%
- #12 Surgeon Simulator: Experience Reality
88% matchMixed57% of 1,197 reviews2016
Dev: Bossa Studios
Windows
Median: 54 minMean: 2.2 hrs≥1hr: 47%
Surgeon Simulator is bringing the ER to VR! The most critically acclaimed and infamous surgery simulation game as you have never seen it before! Featuring all of the surgeries and twisted humour of the original favourite plus a few new surprises...
Why similar: Medical Sim 72.6% ★, Simulation 17.5%, Action 7.1%, Funny 2.8%
- #13 Doctor Simulator
87% matchNo user reviews
Dev: Medic Labs
Windows
If you have ever thought of becoming a doctor – here is your chance! Arm yourself in a stethoscope and do a ward round to keep up to date with your patients’ condition. They may complain and question your authority but remember – you’re the doctor!
Why similar: Medical Sim 46.1% ★, Simulation 33.8%, Action 18.9%, Adventure 0.9%, Singleplayer 0.4%
- #14 疑義照会ウォーズ
86% matchMostly Negative30% of 20 reviews2021
Dev: 薬学ゲーム開発プロジェクト
Windows
This is a full-fledged adventure game (selectable type) based on the theme of the pharmacist's job, "checking prescription. Determine if the prescription is correct, and if it is, make a "Questionable Inquiry" to the doctor!
Why similar: Medical Sim 77.5% ★, Simulation 18.2%, 2D 3.8%, Singleplayer 0.5%
- #15 Two Point Hospital
84% matchVery Positive92% of 34,380 reviews2018
Dev: Two Point StudiosPub: SEGA
Windows · Mac · Linux
Median: 5.5 hrsMean: 34.9 hrs≥1hr: 89%
Design stunning hospitals, cure peculiar illnesses and manage troublesome staff as you spread your budding healthcare organisation across Two Point County.
Why similar: Medical Sim 73.5% ★, Simulation 20%, Funny 4.1%, Cartoony 1.9%, Singleplayer 0.5%
- #16 Love Hospital
86% matchNo user reviews2026
Dev: KXMstudio
Windows
"Love Hospital" is a comedy romance simulation game where you can enjoy sweet relationships with beautiful nurses. Experience the fun and laughter-filled romance unfolding in the hospital!"
Why similar: Medical Sim 57% ★, Visual Novel 15.1%, Simulation 9.5%, Anime 7.4%, Choices Matter 6%
- #17 型神:初见
85% matchNo user reviews
Dev: 戏宫科技
Windows
全球首款医美手术模拟与视觉小说相结合的游戏!你将通过神奇的医美技术改变命运,体验30场精密手术,揭开时间与美丽背后的秘密。你的每一次操作,都在重塑他人的人生。
Why similar: Medical Sim 69.6% ★, Simulation 12.8%, Anime 9.7%, 2D 4.3%, Story Rich 3.1%
- #18 Heart's Medicine - Time to Heal
83% matchVery Positive94% of 878 reviews2016
Dev: Blue GiraffePub: GameHouse
Windows · Mac
Median: 6.0 hrsMean: 12.1 hrs≥1hr: 92%
An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring surgeon at Little Creek Hospital!
Why similar: Medical Sim 81.7% ★, Simulation 13.8%, Adventure 2.3%, Story Rich 1.7%, Singleplayer 0.5%
- #19 Fun Hospital
84% matchMixed64% of 596 reviews2018
Dev: OrangesGame Technology Limited
Windows · Mac
Median: 1.2 hrsMean: 33.2 hrs≥1hr: 53%
Build your own theme hospital! Here, you might meet patients with a lot of hair, or no hair; strange aliens, evil guy, super hero…
Why similar: Medical Sim 75.5% ★, Simulation 24.5%
- #20 My Universe - Pet Clinic Cats & Dogs
82% matchMixed62% of 29 reviews2020
Dev: It Matters GamesPub: Microids
Windows
Discover the veterinary profession and help cats and dogs that need you. An injury, fever, an animal that refuses to eat: it’s up to you to act!
Why similar: Medical Sim 72.1% ★, Simulation 23.2%, Colorful 4.2%, Singleplayer 0.5%
- #21 Hospital Manager
82% matchMixed46% of 254 reviews2015
Dev: CCCPPub: Microids Indie
Windows · Mac
Median: 1.1 hrsMean: 9.5 hrs≥1hr: 56%
Experience something novel, bursting with extraordinary phenomena and strange situations in your hospital! Only you have the power to make the best decisions and to make your hospital the most popular one! But beware: Several events will add some spice to your life! Embark on the career of your life!
Why similar: Medical Sim 82.5% ★, Simulation 17.5%
- #22 Ice Rescue Simulator VR
81% matchNo user reviews
Dev: Sempiternal Rain
Windows
Ice Rescue Simulator VR – a fun ice emergency rescue simulator where a victim’s life is in your hands, and any wrong move can lead to failure!
Why similar: Medical Sim 76.9% ★, Simulation 13.7%, Arcade 9.1%, Singleplayer 0.3%
- #23 Medical Diagnostic Simulator
80% matchMostly Negative25% of 16 reviews2024
Dev: Arktos Cat
Windows
Play as a general practitioner in this text-based medical simulation game. Consult, examine, and diagnose your patients in your own medical practice.
Why similar: Medical Sim 70.2% ★, Simulation 29%, Singleplayer 0.8%
- #24 中医模拟传承人
79% matchPositive86% of 14 reviews2024
Dev: guizhi0011
Windows
A game where everyone can learn traditional Chinese medicine.
Why similar: Medical Sim 72.1% ★, Simulation 25.3%, 2D 2.1%, Singleplayer 0.5%
- #25 Opawration!
81% matchNo user reviews
Dev: chinchingames
Windows
A 2D, veterinarian horror game. In this game, select the appropriate treatment and treat patients with topical products injections, surgeries. Treat patients over the course of 7 days, using the in-game computer to research the best treatment option. Playtime is 30 minutes.
Why similar: Medical Sim 73% ★, Simulation 11.9%, Choices Matter 6.1%, Cartoony 5.8%, 2D 2.7%
- #26 First Steps in Child Developmental Support
79% match9 user reviews100% of 9 reviews2025
Dev: エムテラス
Windows
Yuuka, a nursing student, is doing a summer practicum at a Child Development Support Center. Explore the facility in a role-playing format and experience child support activities. Learn about medical care, therapeutic interventions, and home healthcare over three days.
Why similar: Medical Sim 77.4% ★, Anime 12.2%, Adventure 5.1%, Choices Matter 4.8%, Singleplayer 0.5%
- #27 VR TKA Surgery Simulator
78% match2 user reviews0% of 2 reviews2024
Dev: Kliniker
Windows
Get ready to learn all the subtleties of the surgery by practicing it in the applied VR TKA training by Prof. Dr. Ertugrul Aksahin, one of the world's leading orthopedic surgeons!
Why similar: Medical Sim 70.6% ★, Simulation 28.7%, Singleplayer 0.6%
- #28 Human Constructor VR
78% match3 user reviews67% of 3 reviews2020
Dev: Exxit
Windows
Human Constructor VR is a virtual reality application designed for detailed study of the human structure and individual organs, bones, and muscles. This application contains only the anatomy of the male human body.
Why similar: Medical Sim 83.6% ★, Simulation 15.6%, Singleplayer 0.8%
- #29 Pompiers Simulator
76% match4 user reviews100% of 4 reviews2025
Dev: Vincent TartarPub: Oasis Video Games
Windows
You’re not a firefighter, but you dream of experiencing the intensity of a real emergency rescue operation? Pompiers Simulator puts you at the heart of first aid missions, in the shoes of a responder, within a simulation designed by real firefighters.
Why similar: Medical Sim 77.3% ★, Simulation 15.2%, Choices Matter 4.3%, 2D 2.9%, Singleplayer 0.4%
- #30 Мне только спросить!
77% matchNo user reviews
Dev: Каракули
Windows
"I just want to ask!" is a medical registrar simulator with time management elements set in a provincial Russian hospital, featuring humorous elements. Your main task is to help patients, but each one has their own story.
Why similar: Medical Sim 76% ★, Simulation 15.6%, Choices Matter 4.6%, 2D 3.5%, Singleplayer 0.3%
- #31 Scalpel, Please!
77% matchNo user reviews
Dev: WoolCat Games
Windows
Scalpel, Please! is a ridiculous medical simulator where you assist a blindfolded surgeon. Provide tools, talk to him, and give your full support. But be careful: he’ll remember everything you do and react accordingly. Will you manage to keep your job?
Why similar: Medical Sim 69.1% ★, Simulation 23.5%, Funny 5.4%, Story Rich 1.7%, Singleplayer 0.3%
- #32 Valley General Hospital: NiVR
76% match2 user reviews50% of 2 reviews2021
Dev: Valley General
Windows
An exciting new approach to training and simulation in Healthcare.
Why similar: Medical Sim 72.4% ★, Simulation 23.8%, Choices Matter 3.4%, Singleplayer 0.3%
- #33 PSY in Apocalypse
75% matchNo user reviews
Dev: Quantum Strawberry
Windows
PSY in Apocalypse는 사실적인 2D 정신과 어드벤처 게임입니다. 여러분은 게임 속에서 정신과 의사가 되어 환자들을 직접 치료하게 됩니다. 포스트 아포칼립스 세계를 의사의 관점이라는 다소 새로운 시각으로 이야기를 풀어나가게 됩니다.
Why similar: Medical Sim 78.7% ★, Simulation 9.3%, 2D 4.6%, Story Rich 3.5%, Adventure 3.1%
- #34 Medic Simulator
75% matchNo user reviews
Dev: Eathrabaria
Windows
Become a doctor and treat patients in every area of medicine. Become a cardiologist, psychiatrist, dentist, dermatologist, oncologist, surgeon, ophthalmologist, neurologist…!
Why similar: Medical Sim 67.8% ★, Simulation 27.2%, Choices Matter 4.4%, Singleplayer 0.5%
- #35 Over the Counter
73% matchVery Positive91% of 399 reviews2022
Dev: Brody Rampono
Windows · Mac · Linux
A pharmaceutical business management game.
Why similar: Medical Sim 75.6% ★, Simulation 20.8%, 2D 3%, Singleplayer 0.5%
- #36 Until The End
74% match9 user reviews56% of 9 reviews2022
Dev: Red Sorel Games
Windows
In Until The End, you play as Zoe, a young nurse who has just graduated. At the Montagne Institute, you will help her make the best decisions for the well-being of her patients in a palliative care unit.
Why similar: Medical Sim 57% ★, Visual Novel 14.8%, Simulation 12.5%, Choices Matter 6.3%, Funny 4.1%
- #37 Emergency Room Simulator
74% matchNo user reviews
Dev: Caipirinha GamesPub: Aerosoft
Windows
In Emergency Room Simulator, you become a dedicated doctor in the emergency room, responsible for diagnosing and treating patients as well as saving lives. This professional simulation offers an immersive experience of working in a fast-paced medical environment.
Why similar: Medical Sim 72.3% ★, Simulation 27.3%, Singleplayer 0.4%
- #38 Oops! INC. Emergency Center
72% match4 user reviews100% of 4 reviews2026
Dev: CCS
Windows
Run the galaxy’s most chaotic hospital in Oops! INC. Emergency Center! Play as a diploma-free robot doctor, diagnose bizarre space illnesses, craft the right remedies, and treat patients fast before insurance turns you into a fridge. Funny, frantic, and out of this world!
Why similar: Medical Sim 76.8% ★, Simulation 15.9%, Funny 6.9%, Singleplayer 0.4%
- #39 ring of the devil
73% match1 user reviews0% of 1 reviews2024
Dev: ring of the devil
Windows
This is a fighting game.
Why similar: Medical Sim 68.7% ★, Simulation 30.7%, Singleplayer 0.7%
- #40 My Universe - Doctors & Nurses
73% matchMostly Negative29% of 14 reviews2022
Dev: It Matters GamesPub: Microids
Windows · Mac
Take turns to play either a doctor or nurse. Diagnose illnesses and infections so as to treat and help your many patients. Set out on an adventure in a buzzing hospital environment. Meet all sorts of different characters and discover a story full of surprises.
Why similar: Medical Sim 76.7% ★, Simulation 16.3%, Colorful 6.2%, Singleplayer 0.7%
- #41 Sister's Curriculum After Story
71% matchPositive100% of 16 reviews2025
Dev: WAZAZAK
Windows
The Story of Tutoring Top 1% Repeat Students Sisters, After.
Why similar: Simulation 40.1%, Visual Novel 27.2%, Anime 15.6%, Colorful 7.3%, 2D 6.7%
- #42 Doctor Dash ASMR Hospital
70% matchVery Positive90% of 93 reviews2024
Dev: Friedegggames OUPub: Brightika, Inc.
Windows
💊 Your dream hospital awaits! 🏥❤️ Addictive levels and unique locations ✈️ Hours of entertainment in the time-management genre ⏰
Why similar: Medical Sim 72.6% ★, Simulation 22.1%, 2D 4.6%, Singleplayer 0.7%
- #43 Vital Signs: Emergency Department
72% matchMixed56% of 73 reviews2020
Dev: BreakAway Games
Windows · Mac
Play a doctor in Vital Signs: Emergency Department and challenge your medical knowledge to help treat a wide array of cases who come into the ER.
Why similar: Medical Sim 73.4% ★, Simulation 13.4%, Choices Matter 4.9%, Colorful 3.9%, 2D 3.6%
- #44 Wilderness
71% match2 user reviews50% of 2 reviews2024
Dev: chen youzhen
Windows
This game transports you into a vibrant world where numerous players transform into little snakes competing to grow on an expansive map.
Why similar: Medical Sim 69.1% ★, Simulation 28.1%, Story Rich 2.2%, Singleplayer 0.5%
- #45 MediSim: Emergency Response
71% matchNo user reviews
Dev: Mehmet Hilmi Değirmenci
Windows
As a young doctor, save lives in emergencies, advance from a health center to a major hospital, and manage your own facility. Perform first aid, and diagnostics, take on ambulance and helicopter missions, and build your medical team. A realistic medical simulation where every decision matters!
Why similar: Medical Sim 73.3% ★, Simulation 26.3%, Singleplayer 0.4%
- #46 Witch Please: Sex Service
68% matchMostly Positive74% of 88 reviews2025
Dev: AquilonPub: Dreamers Workshop
Windows
Inherit a potion shop, a pile of debt, and a line of horny clients. Brew potions from lust, serve pleasure on demand, and uncover your father’s secret elixir. In this erotic witch sim, sex is currency — and you’re the main provider.
Why similar: Medical Sim 44.6% ★, Visual Novel 12.3%, Simulation 11.7%, Arcade 10.1%, Anime 9.3%
- #47 Donor Clinic Simulator
70% matchNo user reviews
Dev: 2 Stula Games
Windows
Manage your own reproductive medicine clinic! Choose donors based on their physical traits, research the effectiveness of biomaterials, upgrade the donor room, improve your laboratory, purchase new equipment, and help couples have a baby and become happy parents!
Why similar: Medical Sim 68.1% ★, Simulation 27.9%, Choices Matter 3.6%, Singleplayer 0.3%
- #48 SimShock2025
68% match7 user reviews75% of 8 reviews2025
Dev: Pablo Kessler SaizPub: Pablo Kessler
Windows · Mac
SimShock2025 is a free, bilingual (EN/ES) hemodynamic shock simulator. Treat cardiogenic, hemorrhagic, and septic shock using real drugs and interventions. Written in PureBasic, available for Mac and Windows. Apple-signed and notarized.
Why similar: Medical Sim 63.6% ★, Simulation 25.4%, Funny 5%, 2D 3.9%, Story Rich 1.8%
- #49 PST VR (Primary Surgical Treatment)
70% matchMixed55% of 29 reviews2020
Dev: Adelante LTD
Windows
“Primary surgical treatment” is a virtual simulator, designed for education purposes. By immersing yourself with your pair of Oculus VR Headsets, you can experience the task of treating a wound with many available surgical instruments and help the patient to begin the recovery.
Why similar: Simulation 56%, Medical Sim 44% ★
- #50 Antidote to despair
69% matchNo user reviews
Dev: Gamet
Windows
An antidote shop simulator in Paris. Who will you save: your son, who cynically kills unwanted people, or a mad fanatic who poisons people for the sake of "rebirth"?
Why similar: Medical Sim 62% ★, Simulation 14.7%, Visual Novel 9.9%, Choices Matter 6.6%, 2D 3%
- #51 Royal Dental
67% match3 user reviews100% of 3 reviews2026
Dev: Visionaire Labs
Windows
Rise from peasant dentist to royal healer in this quirky medieval dental simulation RPG. Treat patients, upgrade tools, improve your clinic, expand your knowledge, and restore Princess Penelope’s legendarily awful smile, all while facing sabotage from a jealous prince.
Why similar: Medical Sim 72.8% ★, Simulation 15.2%, Funny 7.2%, Cartoony 4.7%, Singleplayer 0.2%
- #52 First Steps in the NICU (Discovery edition)
67% match6 user reviews100% of 6 reviews2025
Dev: エムテラス
Windows
Welcome to “First NICU Experience”! Experience neonatal care in this serious game. As a nursing student, work with medical staff and families to care for infants and tackle post-discharge challenges. With interactive choices and story-driven gameplay, learn key skills in 1 hour.
Why similar: Medical Sim 76.4% ★, Anime 11.9%, Adventure 5.5%, Choices Matter 5.5%, Singleplayer 0.6%
- #53 Flying Circus
69% match3 user reviews67% of 3 reviews2020
Dev: poliko; entertainment
Windows
Parents left sector hotel-oscar-mike-echo, we can proceed with operation Flying Circus. Lead our units to defeat the enemy, and gain control over all toys in the house.
Why similar: Simulation 57%, Action 34.8%, Arcade 8.2%
- #54 Another Bar Game
67% matchPositive95% of 19 reviews2023
Dev: Arik Games
Windows · Linux
A casual action game where you serve craft beer to thirsty bar guests. Become the most popular bartender in town! Wash glasses, clean tables and keep everybody happy!
Why similar: Simulation 24.5%, Arcade 22.4%, Cartoony 15.7%, Action 15.3%, Funny 9.8%
- #55 The Book of Plagues
65% matchPositive91% of 22 reviews2026
Dev: DiaMMax Games
Windows
The city is drowning in Plague. Panic, hunger, and fear are tearing it apart. You are the last one who can change its fate: heal it, hold it back from collapse… or drive it to ruin with your own hands!
Why similar: Medical Sim 54.7% ★, Visual Novel 12.4%, Arcade 9.8%, Simulation 7.8%, Funny 5.2%
- #56 MiM: Meditation Interactive Matrix
68% matchNo user reviews2025
Dev: In Stereo Games
Windows · Linux
A sci-fi wellness playground that invites you to balance mind and body through guided chakra sessions, zero-G arcade mini-games, dynamic rain & thunder simulations, and customizable color-noise soundscapes.
Why similar: Medical Sim 55.7% ★, Simulation 24.1%, Arcade 15.6%, Colorful 4.4%, Singleplayer 0.2%
- #57 Bounce ASMR
66% matchMostly Negative39% of 46 reviews2024
Dev: edybtt Studios
Windows · Mac · Linux
Relax your brain with some geometric bouncing. Bounce ASMR is right here!
Why similar: Simulation 52%, Arcade 28.9%, Colorful 9.1%, 2D 8.4%, Singleplayer 1.5%