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Games Like Elixir

60+ similar titles based on shared tags and player behavior. Themes include Medical Sim, Simulation, Singleplayer, Puzzle.

Elixir header art

Welcome to Elixir, a 2D strategic puzzle experience. Become an ancient alchemist with a mysterious past to unlock. Explore & find lost souls who need your help. Uncover Elixirs and experiment on them, and yourself. Embark on a dark journey to solve puzzles, unlock recipes and unearth hidden secrets.

Reviews: Positive — 93% — of 43 reviews
Released: 2024-07-29
Developer: Moxu Projects
Genres: Adventure, Casual, Indie, Simulation
Platforms: Windows

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  1. #1 Opawration!
    97% matchNo user reviews
    Dev: chinchingames
    Windows

    A 2D, veterinarian horror game. In this game, select the appropriate treatment and treat patients with topical products injections, surgeries. Treat patients over the course of 7 days, using the in-game computer to research the best treatment option. Playtime is 30 minutes.

    Why similar: Medical Sim 61.1%, Point & Click 11.6%, Multiple Endings 7.7%, Dark 6.4%, Hand-drawn 5.8%

  2. #2 Do No Harm
    96% matchMostly Positive75% of 901 reviews2025
    Dev: Darts Games
    Windows
    Median: 2.5 hrsMean: 5.9 hrs≥1hr: 76%

    Lovecraftian Doctor Simulator. Diagnose patients by analyzing unsettling symptoms and treat them using your Book of Medicine. Make moral choices — decide who to save or kill, discover whom to trust, and unlock multiple endings! Can you endure 30 days of perilous decisions?

    Why similar: Medical Sim 47.1%, Investigation 14.2%, Medieval 7.6%, Point & Click 7.1%, Multiple Endings 6.2%

  3. #3 Psyhonds
    96% match8 user reviews63% of 8 reviews2026
    Dev: Meriteri GamesPub: Terrabyte Games
    Windows

    A satirical mental hospital survival simulator: control four unstable characters, craft from junk, forge dubious alliances, communicate with patients and staff, and choose between a quiet life in a ward, a riot, or a risky escape to freedom.

    Why similar: Medical Sim 65.8%, Crafting 13.8%, Puzzle 7.5%, Hand-drawn 5%, Simulation 4.8%

  4. #4 The Apothecary
    95% matchNo user reviews
    Dev: Rufalicious Gaming
    Windows

    The realm depends on your help: mix ingredients and create potions to cure wild, fantastical illnesses that befall your fellow citizens. But be warned, you are all on your own. Enjoy figuring out which ingredients work and which don't -- curing or killing those who ask for your help!

    Why similar: Medical Sim 61.7%, Point & Click 8.3%, Medieval 6.9%, Simulation 6%, Dark Fantasy 5.4%

  5. #5 Ice Rescue Simulator VR
    94% matchNo user reviews
    Dev: Sempiternal Rain
    Windows

    Ice Rescue Simulator VR – a fun ice emergency rescue simulator where a victim’s life is in your hands, and any wrong move can lead to failure!

    Why similar: Medical Sim 70.5%, Crafting 15.6%, Puzzle 8.5%, Simulation 5%, Singleplayer 0.4%

  6. #6 Ultrasound
    94% matchNo user reviews
    Dev: Walter Woods
    Windows

    A sci-fi horror 3D point&click game. Use an ultrasound machine to diagnose and do surgery on a grotesque infection spreading aboard a space freighter. Craft meds, upgrade your machine, find new surgical tools, and restore ship systems before you collide with a star. Soon, something will be born.

    Why similar: Medical Sim 54%, Crafting 13.3%, Point & Click 9.2%, Exploration 7.7%, Puzzle 6.6%

  7. #7 Antidote to despair
    93% match6 user reviews83% of 6 reviews2026
    Dev: Gamet
    Windows

    An antidote shop simulator in Paris. Who will you save: your son, who cynically kills unwanted people, or a mad fanatic who poisons people for the sake of "rebirth"?

    Why similar: Medical Sim 53.4%, Point & Click 10%, Puzzle 7.2%, Dark 6.1%, Stylized 6%

  8. #8 Dr. Cares - Amy's Pet Clinic
    92% matchMostly Positive79% of 76 reviews2018
    Dev: NitrealPub: GameHouse
    Windows · Mac

    Get ready to test your vet skills in Dr. Cares - Amy's Pet Clinic!

    Why similar: Medical Sim 80.9%, Simulation 9.6%, Casual 5.4%, Adventure 4.1%

  9. #9 S4Game
    91% matchNo user reviews
    Dev: Viral Studios
    Windows

    S4Game aims to provide health professionals with an innovative approach to acquire soft skills to foster their professional development. Their main learning objective is the acquisition of soft skills required during work in an operating room, such as communication or teamwork.

    Why similar: Medical Sim 72.9%, Investigation 21.9%, Simulation 2.8%, Casual 1.5%, Singleplayer 0.9%

  10. #10 Plague M.D.
    91% matchMostly Positive76% of 161 reviews2020
    Dev: CosCom Art Group
    Windows · Linux

    Plague M.D. is a medieval medicine simulator. Become a quack doctor stuck in a backwater village in the 16th century.

    Why similar: Medical Sim 32.7%, Point & Click 13.9%, Hand-drawn 11.5%, Medieval 8.6%, Simulation 8.4%

  11. #11 The Death Handover
    89% matchNo user reviews
    Dev: Micronovae
    Windows

    Play as a novice mortician where every 'Death Handover' hides an unpaid debt. Through 'Soul-Returning,' relive final moments to break a five-life cycle. More than a simulation, it’s a rehearsal for death—until the next name on the list feels terrifyingly familiar.

    Why similar: Medical Sim 56.4%, Investigation 14.7%, Simulation 7.3%, Point & Click 5.3%, Puzzle 4.4%

  12. #12 Medical verdict
    89% matchMixed57% of 53 reviews2018
    Dev: Volokitin Andrey
    Windows

    Here is a fun simulator of passing a medical examination in the Chelyabinsk clinic with realistic graphics and interesting gameplay! Take the coronavirus test! Collect as many virtual health points as you can, but remember ... this is just a game!

    Why similar: Medical Sim 86.6%, Simulation 8.7%, Casual 4.7%

  13. #13 Heart's Medicine - Hospital Heat
    88% matchVery Positive96% of 366 reviews2017
    Dev: Blue GiraffePub: GameHouse
    Windows · Mac
    Median: 5.1 hrsMean: 8.7 hrs≥1hr: 93%

    The long awaited sequel to "Heart's Medicine - Time to Heal". An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring doctor at Little Creek Hospital!

    Why similar: Medical Sim 83.2%, Simulation 8.3%, Casual 4.8%, Adventure 3.7%

  14. #14 Doctor Dash ASMR Hospital
    86% matchVery Positive89% of 94 reviews2024
    Dev: Friedegggames OUPub: Brightika, Inc.
    Windows

    💊 Your dream hospital awaits! 🏥❤️ Addictive levels and unique locations ✈️ Hours of entertainment in the time-management genre ⏰

    Why similar: Medical Sim 66.5%, Point & Click 15.5%, Simulation 8.1%, Casual 5.1%, 2D 4%

  15. #15 CANDY HOUSE in the DARK FOREST
    86% matchNo user reviews
    Dev: CHAyE
    Windows

    An RPG in which you make desserts to uncover mysteries. Choices may affect endings. The abandoned siblings encountered a good witch, a freaky doll, and gingerbread twins, they disclose sugary "lies"—revealing the candy house's rewritten history and a selfish truth related to their past...

    Why similar: Investigation 16.6%, Point & Click 12.3%, Crafting 9.7%, Puzzle 9.6%, Multiple Endings 9.6%

  16. #16 PSY in Apocalypse
    85% matchNo user reviews
    Dev: Quantum Strawberry
    Windows

    PSY in Apocalypse는 사실적인 2D 정신과 어드벤처 게임입니다. 여러분은 게임 속에서 정신과 의사가 되어 환자들을 직접 치료하게 됩니다. 포스트 아포칼립스 세계를 의사의 관점이라는 다소 새로운 시각으로 이야기를 풀어나가게 됩니다.

    Why similar: Medical Sim 76%, Puzzle 7.7%, Atmospheric 4.7%, 2D 4.2%, Simulation 3.6%

  17. #17 Pentamania: Alchemy Madness
    84% match4 user reviews50% of 4 reviews2025
    Dev: Athmyx
    Windows

    Step into a VR alchemy workshop, gather rare ingredients, and combine them with cauldrons, and magical machines to brew fantastical potions. Experiment, discover, and deliver your creations in an immersive fantasy experience!!

    Why similar: Medical Sim 60.5%, Crafting 10.9%, Puzzle 9.7%, Simulation 9.6%, Casual 5.9%

  18. #18 Wound Man
    83% matchPositive95% of 22 reviews2023
    Dev: Aspidochelone Studios
    Windows

    Wound Man is a macabre jigsaw puzzle adventure where you reconstruct a tortured figure from centuries-old anatomical art. Uncover hidden secrets and collect strange curiosities with every piece.

    Why similar: Medical Sim 37.1%, Investigation 18.5%, Multiple Endings 9.7%, Hand-drawn 9.4%, Puzzle 8.5%

  19. #19 Pompiers Simulator
    82% match4 user reviews100% of 4 reviews2025
    Dev: Vincent TartarPub: Oasis Video Games
    Windows

    You’re not a firefighter, but you dream of experiencing the intensity of a real emergency rescue operation? Pompiers Simulator puts you at the heart of first aid missions, in the shoes of a responder, within a simulation designed by real firefighters.

    Why similar: Medical Sim 75.8%, Point & Click 12.1%, Simulation 5.9%, Pixel Graphics 3.1%, 2D 2.7%

  20. #20 Surgeon Simulator VR: Meet The Medic
    84% matchMostly Positive76% of 586 reviews2016
    Dev: Bossa Studios
    Windows
    Median: 18 minMean: 1.7 hrs≥1hr: 14%

    Surgeon Simulator VR: Meet the Medic – be the Medic and operate on the Heavy in this free and exclusive teaser for the HTC Vive!

    Why similar: Medical Sim 94.1%, Simulation 5.9%

  21. #21 Мне только спросить!
    82% matchNo user reviews
    Dev: Каракули
    Windows

    "I just want to ask!" is a medical registrar simulator with time management elements set in a provincial Russian hospital, featuring humorous elements. Your main task is to help patients, but each one has their own story.

    Why similar: Medical Sim 75.4%, Point & Click 12%, Simulation 6.2%, 2D 3.3%, Atmospheric 2.7%

  22. #22 Reanimation Inc.
    81% matchVery Positive84% of 130 reviews2019
    Dev: Dmitrii Lomakin
    Windows

    Reanimation inc is a completely realistic simulation - real urgent conditions and diseases, real protocols of care used in an ambulance, realistic simulation of the body! Do you like realistic games about medicine and simulators, games you need to think about? You 'll be happy!

    Why similar: Medical Sim 90.6%, Simulation 9.4%

  23. #23 Morbus: The Burden Of The Apothecary
    80% matchNo user reviews
    Dev: Viktor PekarPub: Introverse Interactive
    Windows · Linux

    A top-down plague simulation RPG set in a living medieval tapestry. Play the last apothecary in a dying town treating the sick, containing the outbreak, and navigating the politics of factions who'd sooner see you burn.

    Why similar: Medical Sim 63.9%, Medieval 14.1%, Stylized 6.8%, Multiple Endings 5.2%, Simulation 4.2%

  24. #24 Heart's Medicine - Time to Heal
    81% matchVery Positive94% of 883 reviews2016
    Dev: Blue GiraffePub: GameHouse
    Windows · Mac
    Median: 6.0 hrsMean: 12.1 hrs≥1hr: 92%

    An intense, but also funny, medical drama that deals with a lot of life-changing decisions. Become an aspiring surgeon at Little Creek Hospital!

    Why similar: Medical Sim 86.1%, Simulation 5.8%, Casual 5.1%, Adventure 2.4%, Singleplayer 0.6%

  25. #25 Sefton Asylum
    79% matchNo user reviews2026
    Dev: Clever Trickster Productions
    Windows

    Care. Investigate. Survive. Play as a night nurse in a secluded asylum. Every night is a choice: find your missing brother, secretly gather evidence of forbidden experiments or keep your patients alive before they come back to haunt Sefton’s wards.

    Why similar: Medical Sim 48.2%, Investigation 15.3%, Multiple Endings 7.9%, Mystery 6.6%, Exploration 6.4%

  26. #26 Caduceus Quest
    79% match1 user reviews100% of 1 reviews2025
    Dev: Resilient Games Studio, LLC
    Windows

    Caduceus Quest is a single-player RPG in which players use the scientific process to solve a medical mystery that poses a growing threat to your small town. You must learn from and enlist the help of local science professionals and complete strategic mini-games to identify and resolve the threat.

    Why similar: Medical Sim 59%, Investigation 20.2%, Mystery 7.4%, Hand-drawn 7%, Exploration 6.2%

  27. #27 Arcane Eclipse
    78% matchNo user reviews
    Dev: LeinArtLabs
    Windows

    Find a way to bring back the sun from this everlasting eclipse.

    Why similar: Point & Click 21.8%, Puzzle 12.6%, Dark Fantasy 11.8%, Exploration 11.8%, Medieval 11.3%

  28. #28 Scrutator Tenebris
    77% matchNo user reviews
    Dev: Empty Die Studio
    Windows

    Become a pathologist in a sinister mansion filled with unsolved mysteries. Examine bodies and make decisions that alter the course of the investigation. Your choices shape multiple story endings in this narrative-driven psychological horror — where every secret could cost your sanity.

    Why similar: Medical Sim 37.2%, Investigation 20.7%, Mystery 8.7%, Puzzle 5.5%, Simulation 4.9%

  29. #29 Royal Dental
    75% match3 user reviews100% of 3 reviews2026
    Dev: Visionaire Labs
    Windows

    Rise from peasant dentist to royal healer in this quirky medieval dental simulation RPG. Treat patients, upgrade tools, improve your clinic, expand your knowledge, and restore Princess Penelope’s legendarily awful smile, all while facing sabotage from a jealous prince.

    Why similar: Medical Sim 70%, Medieval 14.4%, Multiple Endings 6%, Simulation 5.8%, Stylized 3.4%

  30. #30 The Tooth Fae
    76% matchNo user reviews
    Dev: Ev
    Windows

    A nightmarish dental simulator where you sneak into townsfolks' homes to steal their teeth. An expanded version of the Ludum Dare 58 game of the same name, made by a solo developer.

    Why similar: Medical Sim 69%, Simulation 6.6%, Dark Fantasy 6%, Dark 3.7%, Pixel Graphics 3.4%

  31. #31 A Long Road Home
    78% matchPositive88% of 49 reviews2017
    Dev: One Bit Studio
    Windows
    Median: 3.6 hrsMean: 4.1 hrs≥1hr: 98%

    A Long Road Home is a successor to the point and click adventure games of the past. Explore a mystical fantasy land ruled by a ruthless tyrant, collect items during your travels and test your wit while solving the puzzles in your way. It is up to you to lead an unlikely hero back to his family.

    Why similar: Investigation 17.2%, Point & Click 14.7%, Multiple Endings 10.6%, Dark Fantasy 9.9%, Exploration 9.6%

  32. #32 Dr Greenstuff
    77% matchVery Positive87% of 148 reviews2018
    Dev: Black DiskettePub: Black Diskette Studio
    Windows

    Discover the life of Dr Greenstuff, grow marijuana, coca, make meth', drugs and more to keep your legal/illegal business running.

    Why similar: Medical Sim 89.6%, Simulation 10.4%

  33. #33 Bacterium / 生命之旅
    76% matchPositive84% of 49 reviews2018
    Dev: Dragon Whisper GamePub: Zodiac Interactive
    Windows

    In the coming decades, a huge breakthrough in nano-medical technology will bring a new light to cure terminally ill patients. As a nano-robot operator, you will be involved in a battle between nanobots and diseases!

    Why similar: Medical Sim 86.4%, Simulation 9.4%, Adventure 4.2%

  34. #34 Dr. Chatelet: Faith 神医
    74% matchVery Positive85% of 132 reviews2022
    Dev: MuccyGames
    Windows · Mac

    Amputations, bloodletting, alchemy - all of which seem unthinkable today - were the treatment options that medieval doctors revered. You must face challenges one after another and experience gains and losses in the course of your constant adventures

    Why similar: Medical Sim 59.1%, Medieval 13.7%, Multiple Endings 7.6%, Stylized 6.4%, Simulation 5.9%

  35. #35 High Mountain Abbey
    73% matchNo user reviews2026
    Dev: David Turner
    Windows · Mac · Linux

    Do you dare to meddle with the mad god? High Mountain Abbey is a stop-motion point-and-click puzzle game that throws you into a strange space. Navigate hand-crafted and photographed dioramas and solve trippy mechanical challenges to contain the forces of madness that have swallowed the abbey.

    Why similar: Point & Click 20.8%, Investigation 18.5%, Exploration 16.4%, Hand-drawn 15.4%, Puzzle 14.3%

  36. #36 Fun Hospital
    75% matchMixed64% of 600 reviews2018
    Dev: OrangesGame Technology Limited
    Windows · Mac
    Median: 1.2 hrsMean: 32.8 hrs≥1hr: 52%

    Build your own theme hospital! Here, you might meet patients with a lot of hair, or no hair; strange aliens, evil guy, super hero…

    Why similar: Medical Sim 82.8%, Simulation 10.9%, Casual 6.3%

  37. #37 疑義照会ウォーズ
    74% matchMostly Negative30% of 20 reviews2021
    Dev: 薬学ゲーム開発プロジェクト
    Windows

    This is a full-fledged adventure game (selectable type) based on the theme of the pharmacist's job, "checking prescription. Determine if the prescription is correct, and if it is, make a "Questionable Inquiry" to the doctor!

    Why similar: Medical Sim 87%, Simulation 8.2%, 2D 4.1%, Singleplayer 0.7%

  38. #38 Smile More
    70% matchVery Positive97% of 217 reviews2026
    Dev: Pixel Poxet
    Windows · Mac

    A short medical simulation horror game with multiple endings where the imperfect are made HAPPY. Perform tasks and operations on sedated patients to fix their defects before submitting your files to the Ministry of Happiness & Peace!

    Why similar: Medical Sim 65%, Multiple Endings 10.5%, Stylized 6.1%, Simulation 5.4%, Atmospheric 3.6%

  39. #39 Field Hospital: Dr. Taylor's Story
    73% matchVery Positive90% of 106 reviews2020
    Dev: Gard Interactive
    Windows · Mac

    Field Hospital is a text-based bureaucratic detective game about hard decisions. Decide who to treat and whom to refuse. Face consequences. Study patients’ info and read their stories. Investigate the tangled case of Dr. Taylor.

    Why similar: Medical Sim 43%, Investigation 12.9%, Point & Click 11.3%, Multiple Endings 8.9%, Puzzle 6.2%

  40. #40 Picot Ether
    73% matchPositive81% of 16 reviews2022
    Dev: Inu to NekoPub: Starship Studio
    Windows

    『ピコエーテル』は新型ウイルスが蔓延した都市を救う薬剤調合シミュレーションゲームです。 プレイヤーは『R-BOWウイルス』が蔓延した都市の診療所医師となり、抗ウイルス薬の開発に勤しみます。

    Why similar: Medical Sim 55.6%, Crafting 14.7%, Medieval 13.1%, Puzzle 7.2%, Simulation 2.7%

  41. #41 Goddess Detective 4
    72% matchMixed69% of 13 reviews2024
    Dev: 2024-NGame
    Windows

    This is a single search for clues to solve the mystery story game, the protagonist of the game called Lucy, is a beautiful detective, there is a house in the home of the mistress of a murder, her daughter died in the bathroom, so she found you, hoping you can investigate the cause here.

    Why similar: Medical Sim 59.8%, Investigation 17%, Medieval 13.8%, Puzzle 7.6%, Simulation 1.1%

  42. #42 本草归元录
    71% matchVery Positive80% of 152 reviews2025
    Dev: Orange Paper StudioPub: CC_Games
    Windows

    "Herbals tycoon" is a game that combines ancient style with deep management strategy, bringing players into a mysterious and fantastic world of traditional Chinese medicine. Here, you are not only a healer but also an explorer, manager, and inheritor, writing your own herbal legend every moment.

    Why similar: Medical Sim 59.9%, Medieval 8.8%, Multiple Endings 8.7%, Exploration 7.8%, Simulation 6.3%

  43. #43 Alien Morgue
    70% matchPositive93% of 30 reviews2026
    Dev: BurGum Games
    Windows

    You're an alien pathologist. Search the Database for alien physiology and dissect bodies to figure out what caused death. Find correct IDs by deceased's features and occupation. Discover weird stuff inside bodies and decide what to do with it. Follow protocols or personal request? Choices matter!

    Why similar: Medical Sim 54.6%, Investigation 15.5%, Multiple Endings 8.7%, Point & Click 8.6%, Puzzle 5.6%

  44. #44 SHEL: The Cure
    71% matchNo user reviews
    Dev: Team Gramps
    Windows

    SHEL: The Cure is a Replicant Diagnostics Simulator. Perform alchemy with spinal fluid, analyze brain scans, commune with otherworldly beings and prescribe treatments with the help of the Manual - an objective and unbiased* guide provided by your interstellar corporate employer.

    Why similar: Medical Sim 51.9%, Investigation 14.3%, Point & Click 11.9%, Puzzle 7.2%, Stylized 5.7%

  45. #45 Follow the meaning
    68% matchVery Positive94% of 998 reviews2024
    Dev: HiKing Mind StudioPub: Second Maze
    Windows · Mac
    Median: 1.8 hrsMean: 2.0 hrs≥1hr: 89%

    Follow the meaning is a surreal point-and-click puzzle adventure. Join detective Paul Trilby as he works to unravel the mysteries of a peculiar town, seemingly ruled by the local Hospital. Over the wall and behind tightly shut gates, a dark secret lies in wait…

    Why similar: Point & Click 19.1%, Investigation 16.3%, Hand-drawn 13%, Puzzle 12.3%, Multiple Endings 11.6%

  46. #46 Shelter from the Storm
    69% matchVery Positive93% of 92 reviews2025
    Dev: Home Groan Games
    Windows

    Rain lashes down soaking you to the bone, you take shelter in a seemingly abandoned house. Navigate through the rooms solving puzzles and trying to escape in this short point & click adventure game.

    Why similar: Investigation 30.9%, Point & Click 25.6%, Pixel Graphics 9.6%, Mystery 9.2%, Puzzle 8.3%

  47. #47 东方药药灵-Touhou Herbalist
    70% matchNo user reviews
    Dev: 樱桃樱桃嘤
    Windows

    ​As a young girl from the Human Village of Gensokyo, you will enter Eientei to learn medicine-making. By fulfilling the requests of its peculiar residents, you may receive their Spell Cards as a reward. Use potions and Spell Cards to experience an extraordinary life in Gensokyo!​

    Why similar: Medical Sim 48.9%, Crafting 21.2%, Pixel Graphics 7.4%, Puzzle 7.2%, Exploration 6.2%

  48. #48 Tell me your Problem
    69% matchNo user reviews
    Dev: Alzakprod.Games
    Windows · Mac

    You think you’re healthy? There’re no healthy people — just those who haven’t been checked enough. And you definitely have problems. Try this pill. And, by the way, that’ll be five gold coins from you. A simulator of a rural psychiatrist who badly needs money.

    Why similar: Medical Sim 50.2%, Multiple Endings 17.5%, Simulation 11%, Puzzle 7.4%, Casual 5.9%

  49. #49 Hospital Manager
    71% matchMixed46% of 254 reviews2015
    Dev: CCCPPub: Microids Indie
    Windows · Mac
    Median: 1.1 hrsMean: 9.5 hrs≥1hr: 56%

    Experience something novel, bursting with extraordinary phenomena and strange situations in your hospital! Only you have the power to make the best decisions and to make your hospital the most popular one! But beware: Several events will add some spice to your life! Embark on the career of your life!

    Why similar: Medical Sim 92.2%, Simulation 7.8%

  50. #50 Welcome Demon
    68% matchNo user reviews2026
    Dev: NurTab
    Windows

    You are a dungeon warden. Sitting in the chair of the previous warden you killed, you must cleanse yourself of your sins within 666 hours. Place the incoming demons into six different dungeons based on your information, intuition, and limited resources.

    Why similar: Medical Sim 49.5%, Point & Click 11.7%, Medieval 10%, Simulation 7%, Multiple Endings 6%

  51. #51 Dilemma
    66% matchPositive100% of 17 reviews2026
    Dev: DrAxelStudio
    Windows

    You don't cure patients; you decide their fate. In this grim medical sim, review records and face impossible bioethical dilemmas. Consult the Medical Bible and choose who gets the bed. Every signature impacts your Ethics, Reputation, and Legal Risk. In a broken system, mercy is a dangerous luxury.

    Why similar: Medical Sim 62.1%, Hand-drawn 10.5%, Dark 6.5%, Simulation 6.2%, Point & Click 5.4%

  52. #52 Vital Signs: Emergency Department
    69% matchMixed56% of 73 reviews2020
    Dev: BreakAway Games
    Windows · Mac

    Play a doctor in Vital Signs: Emergency Department and challenge your medical knowledge to help treat a wide array of cases who come into the ER.

    Why similar: Medical Sim 76.6%, Hand-drawn 8.3%, Simulation 5.6%, Stylized 5%, 2D 3.6%

  53. #53 Plague Doctor: Life in Pestilence
    68% matchNo user reviews
    Dev: PST Games
    Windows

    From an unknown quack to a reputable Plague Doctor, watch the plague unfold before your eyes. Gather ingredients, brew remedies, expand your clinic, and perform surgeries alone or up to 4 player co-op. Will you uphold the Hippocratic Oath... or watch the world rot and darken with every death.

    Why similar: Medical Sim 54.3%, Crafting 15.3%, Medieval 13.8%, Exploration 6.3%, Simulation 5.2%

  54. #54 Prescribe and Pray
    66% matchMostly Positive77% of 66 reviews2026
    Dev: Nuclear Rabbits
    Windows

    Awaken the incompetent doctor within you! Diagnose strange patients, examine their absurd symptoms… and prescribe treatments that could change their lives… or cut them short. Your actions will have consequences.

    Why similar: Medical Sim 64.4%, Multiple Endings 12.8%, Point & Click 8%, Simulation 5.4%, Puzzle 4.3%

  55. #55 Cutting Edge: Roots Of Mutation
    67% matchNo user reviews2026
    Dev: Wizbird Games LLC
    Windows

    Perform life-saving operations in this fast-paced surgery sim. As lizard surgeon Dr. Peri Maddock, you'll treat injuries, excise tumors, and hack corporate organs with speedy, surgical precision. The patient's life is in your claws!

    Why similar: Medical Sim 72.1%, Point & Click 13.1%, Hand-drawn 6%, Simulation 5.4%, 2D 2.5%

  56. #56 Back To The Collis
    67% matchNo user reviews
    Dev: SollersTech
    Windows · Mac · Linux

    Back To The Collis is a story-rich, fully hand-drawn 2D Point & Click adventure puzzle. Embark on a journey alongside the main character, Benjamin, to solve lots of engaging puzzles and explore the town of Collis, outstanding by its memorable populace.

    Why similar: Investigation 24.1%, Point & Click 17.9%, Hand-drawn 14.2%, Puzzle 10.8%, Exploration 8.9%

  57. #57 BLACKWELL
    67% matchNo user reviews2026
    Dev: PolyDraft Studio
    Windows

    You are a Mech plague doctor treating a family infected by a disease that spreads through emotions, and mutates them into monsters. Your choices decide their fate.

    Why similar: Medical Sim 55.4%, Point & Click 11.3%, Multiple Endings 10.1%, Hand-drawn 9.1%, Dark 5.7%

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